Found 257 pleiotropic proteins (16.0 %) and 1345 non-pleiotropic proteins (84.0 %).
1602 items found (page 22 of 33)
| Gene | UniProt | Protein Type | Disease |
|---|---|---|---|
| PER2 | O15055 | non-pleiotropic | Advanced sleep phase syndrome, familial, 1 (FASPS1) [MIM:604348] |
| PEX1 | O43933 | pleiotropic | Peroxisome biogenesis disorder 1A (PBD1A) [MIM:214100] Peroxisome biogenesis disorder 1B (PBD1B) [MIM:601539] Peroxisome biogenesis disorder complementation group 1 (PBD-CG1) [MIM:214100] |
| PEX12 | O00623 | pleiotropic | Peroxisome biogenesis disorder 3B (PBD3B) [MIM:266510] Peroxisome biogenesis disorder complementation group 3 (PBD-CG3) [MIM:614859] |
| PEX2 | P28328 | non-pleiotropic | Peroxisome biogenesis disorder 5B (PBD5B) [MIM:614867] |
| PEX26 | Q7Z412 | pleiotropic | Peroxisome biogenesis disorder 7B (PBD7B) [MIM:614873] Peroxisome biogenesis disorder 7A (PBD7A) [MIM:614872] |
| PEX3 | P56589 | non-pleiotropic | Peroxisome biogenesis disorder 10A (PBD10A) [MIM:614882] |
| PEX7 | O00628 | pleiotropic | Rhizomelic chondrodysplasia punctata 1 (RCDP1) [MIM:215100] Peroxisome biogenesis disorder 9B (PBD9B) [MIM:614879] |
| PFKM | P08237 | non-pleiotropic | Glycogen storage disease 7 (GSD7) [MIM:232800] |
| PFN1 | P07737 | non-pleiotropic | Amyotrophic lateral sclerosis 18 (ALS18) [MIM:614808] |
| PGAM2 | P15259 | non-pleiotropic | Glycogen storage disease 10 (GSD10) [MIM:261670] |
| PGAP2 | Q9UHJ9 | non-pleiotropic | Hyperphosphatasia with mental retardation syndrome 3 (HPMRS3) [MIM:614207] |
| PGK1 | P00558 | non-pleiotropic | Phosphoglycerate kinase 1 deficiency (PGK1D) [MIM:300653] |
| PGM1 | P36871 | pleiotropic | Glycogen storage disease 14 (GSD14) [MIM:612934] Congenital disorder of glycosylation 1T (CDG1T) [MIM:614921] |
| PHC1 | P78364 | non-pleiotropic | Microcephaly 11, primary, autosomal recessive (MCPH11) [MIM:615414] |
| PHEX | P78562 | non-pleiotropic | Hypophosphatemic rickets, X-linked dominant (XLHR) [MIM:307800] |
| PHF6 | Q8IWS0 | non-pleiotropic | Boerjeson-Forssman-Lehmann syndrome (BFLS) [MIM:301900] |
| PHF8 | Q9UPP1 | non-pleiotropic | Mental retardation, X-linked, syndromic, Siderius type (MRXSSD) [MIM:300263] |
| PHGDH | O43175 | non-pleiotropic | Phosphoglycerate dehydrogenase deficiency (PHGDH deficiency) [MIM:601815] |
| PHKA1 | P46020 | non-pleiotropic | Glycogen storage disease 9D (GSD9D) [MIM:300559] |
| PHKB | Q93100 | non-pleiotropic | Glycogen storage disease 9B (GSD9B) [MIM:261750] |
| PHKG2 | P15735 | non-pleiotropic | Glycogen storage disease 9C (GSD9C) [MIM:613027] |
| PHOX2A | O14813 | non-pleiotropic | Congenital fibrosis of extraocular muscles 2 (CFEOM2) [MIM:602078] |
| PHOX2B | Q99453 | non-pleiotropic | Congenital central hypoventilation syndrome (CCHS) [MIM:209880] |
| PHYH | O14832 | non-pleiotropic | Refsum disease (RD) [MIM:266500] |
| PHYKPL | Q8IUZ5 | non-pleiotropic | Phosphohydroxylysinuria (PHLU) [MIM:615011] |
| PIEZO1 | Q92508 | non-pleiotropic | Dehydrated hereditary stomatocytosis with or without pseudohyperkalemia and/or perinatal edema (DHS) [MIM:194380] |
| PIEZO2 | Q9H5I5 | non-pleiotropic | Arthrogryposis, distal, 5 (DA5) [MIM:108145] |
| PIGA | P37287 | pleiotropic | Paroxysmal nocturnal hemoglobinuria 1 (PNH1) [MIM:300818] Multiple congenital anomalies-hypotonia-seizures syndrome 2 (MCAHS2) [MIM:300868] |
| PIGL | Q9Y2B2 | non-pleiotropic | Coloboma, congenital heart disease, ichthyosiform dermatosis, mental retardation and ear anomalies syndrome (CHIME) [MIM:280000] |
| PIGN | O95427 | non-pleiotropic | Multiple congenital anomalies-hypotonia-seizures syndrome 1 (MCAHS1) [MIM:614080] |
| PIGO | Q8TEQ8 | non-pleiotropic | Hyperphosphatasia with mental retardation syndrome 2 (HPMRS2) [MIM:614749] |
| PIGT | Q969N2 | non-pleiotropic | Multiple congenital anomalies-hypotonia-seizures syndrome 3 (MCAHS3) [MIM:615398] |
| PIGV | Q9NUD9 | non-pleiotropic | Hyperphosphatasia with mental retardation syndrome 1 (HPMRS1) [MIM:239300] |
| PIK3CA | P42336 | pleiotropic | Colorectal cancer (CRC) [MIM:114500] Megalencephaly-capillary malformation-polymicrogyria syndrome (MCAP) [MIM:602501] Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi (CLOVE) [MIM:612918] Breast cancer (BC) [MIM:114480] Keratosis, seborrheic (KERSEB) [MIM:182000] Cowden syndrome 5 (CWS5) [MIM:615108] Hepatocellular carcinoma (HCC) [MIM:114550] Ovarian cancer (OC) [MIM:167000] |
| PIK3CD | O00329 | non-pleiotropic | Activated PI3K-delta syndrome (APDS) [MIM:615513] |
| PIK3R1 | P27986 | non-pleiotropic | SHORT syndrome (SHORTS) [MIM:269880] |
| PIK3R2 | O00459 | non-pleiotropic | Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH) [MIM:603387] |
| PIK3R5 | Q8WYR1 | non-pleiotropic | Ataxia-oculomotor apraxia 3 (AOA3) [MIM:615217] |
| PIKFYVE | Q9Y2I7 | non-pleiotropic | Corneal dystrophy, fleck (CFD) [MIM:121850] |
| PINK1 | Q9BXM7 | non-pleiotropic | Parkinson disease 6 (PARK6) [MIM:605909] |
| PIP5K1C | O60331 | non-pleiotropic | Lethal congenital contracture syndrome 3 (LCCS3) [MIM:611369] |
| PITPNM3 | Q9BZ71 | non-pleiotropic | Cone-rod dystrophy 5 (CORD5) [MIM:600977] |
| PITX2 | Q99697 | pleiotropic | Iridogoniodysgenesis 2 (IRID2) [MIM:137600] Axenfeld-Rieger syndrome 1 (RIEG1) [MIM:180500] Ring dermoid of cornea (RDC) [MIM:180550] |
| PKD1 | P98161 | non-pleiotropic | Polycystic kidney disease 1 (PKD1) [MIM:173900] |
| PKD2 | Q13563 | non-pleiotropic | Polycystic kidney disease 2 (PKD2) [MIM:613095] |
| PKHD1 | P08F94 | non-pleiotropic | Polycystic kidney disease, autosomal recessive (ARPKD) [MIM:263200] |
| PKP2 | Q99959 | non-pleiotropic | Arrhythmogenic right ventricular dysplasia, familial, 9 (ARVD9) [MIM:609040] |
| PLA2G5 | P39877 | non-pleiotropic | Fleck retina, familial benign (FRFB) [MIM:228980] |
| PLA2G6 | O60733 | pleiotropic | Neurodegeneration with brain iron accumulation 2A (NBIA2A) [MIM:256600] Neurodegeneration with brain iron accumulation 2B (NBIA2B) [MIM:610217] Parkinson disease 14 (PARK14) [MIM:612953] |
| PLCB4 | Q15147 | non-pleiotropic | Auriculocondylar syndrome 2 (ARCND2) [MIM:614669] |