Found 257 pleiotropic proteins (16.0 %) and 1345 non-pleiotropic proteins (84.0 %).
1602 items found (page 17 of 33)
| Gene | UniProt | Protein Type | Disease |
|---|---|---|---|
| LAMP2 | P13473 | non-pleiotropic | Danon disease (DAND) [MIM:300257] |
| LARS | Q9P2J5 | non-pleiotropic | Infantile liver failure syndrome 1 (ILFS1) [MIM:615438] |
| LARS2 | Q15031 | non-pleiotropic | Perrault syndrome 4 (PRLTS4) [MIM:615300] |
| LCT | P09848 | non-pleiotropic | Congenital lactase deficiency (COLACD) [MIM:223000] |
| LDLRAP1 | Q5SW96 | non-pleiotropic | Hypercholesterolemia, autosomal recessive (ARH) [MIM:603813] |
| LEFTY2 | O00292 | non-pleiotropic | Left-right axis malformations (LRAM) [MIM:601877] |
| LEP | P41159 | non-pleiotropic | Leptin deficiency (LEPD) [MIM:614962] |
| LEPREL1 | Q8IVL5 | non-pleiotropic | Myopia, high, with cataract and vitreoretinal degeneration (MCVD) [MIM:614292] |
| LFNG | Q8NES3 | non-pleiotropic | Spondylocostal dysostosis 3, autosomal recessive (SCDO3) [MIM:609813] |
| LGI1 | O95970 | non-pleiotropic | Epilepsy, familial temporal lobe, 1 (ETL1) [MIM:600512] |
| LHB | P01229 | non-pleiotropic | Hypogonadism LHB-related (HGON-LHB) [MIM:152780] |
| LHCGR | P22888 | pleiotropic | Luteinizing hormone resistance (LHR) [MIM:238320] Familial male precocious puberty (FMPP) [MIM:176410] |
| LHFPL5 | Q8TAF8 | non-pleiotropic | Deafness, autosomal recessive, 67 (DFNB67) [MIM:610265] |
| LHX3 | Q9UBR4 | non-pleiotropic | Pituitary hormone deficiency, combined, 3 (CPHD3) [MIM:221750] |
| LHX4 | Q969G2 | non-pleiotropic | Pituitary hormone deficiency, combined, 4 (CPHD4) [MIM:262700] |
| LIAS | O43766 | non-pleiotropic | Pyruvate dehydrogenase lipoic acid synthetase deficiency (PDHLD) [MIM:614462] |
| LIFR | P42702 | non-pleiotropic | Stueve-Wiedemann syndrome (STWS) [MIM:601559] |
| LIM2 | P55344 | non-pleiotropic | Cataract 19 (CTRCT19) [MIM:615277] |
| LITAF | Q99732 | non-pleiotropic | Charcot-Marie-Tooth disease 1C (CMT1C) [MIM:601098] |
| LMNA | P02545 | pleiotropic | Emery-Dreifuss muscular dystrophy 2, autosomal dominant (EDMD2) [MIM:181350] Muscular dystrophy congenital LMNA-related (MDCL) [MIM:613205] Cardiomyopathy, dilated 1A (CMD1A) [MIM:115200] Lipodystrophy, familial partial, 2 (FPLD2) [MIM:151660] Limb-girdle muscular dystrophy 1B (LGMD1B) [MIM:159001] Cardiomyopathy, dilated, with hypergonadotropic hypogonadism (CMDHH) [MIM:212112] Hutchinson-Gilford progeria syndrome (HGPS) [MIM:176670] Charcot-Marie-Tooth disease 2B1 (CMT2B1) [MIM:605588] Mandibuloacral dysplasia with type A lipodystrophy (MADA) [MIM:248370] Emery-Dreifuss muscular dystrophy 3, autosomal recessive (EDMD3) [MIM:181350] |
| LMNB2 | Q03252 | non-pleiotropic | Partial acquired lipodystrophy (APLD) [MIM:608709] |
| LMX1B | O60663 | non-pleiotropic | Nail-patella syndrome (NPS) [MIM:161200] |
| LPIN2 | Q92539 | non-pleiotropic | Majeed syndrome (MAJEEDS) [MIM:609628] |
| LRBA | P50851 | non-pleiotropic | Immunodeficiency, common variable, 8, with autoimmunity (CVID8) [MIM:614700] |
| LRIT3 | Q3SXY7 | non-pleiotropic | Night blindness, congenital stationary, 1F (CSNB1F) [MIM:615058] |
| LRP2 | P98164 | non-pleiotropic | Donnai-Barrow syndrome (DBS) [MIM:222448] |
| LRP4 | O75096 | pleiotropic | Cenani-Lenz syndactyly syndrome (CLSS) [MIM:212780] Sclerosteosis 2 (SOST2) [MIM:614305] |
| LRP5 | O75197 | pleiotropic | Vitreoretinopathy, exudative 4 (EVR4) [MIM:601813] Osteopetrosis, autosomal dominant 1 (OPTA1) [MIM:607634] High bone mass trait (HBM) [MIM:601884] Endosteal hyperostosis, Worth type (WENHY) [MIM:144750] Van Buchem disease 2 (VBCH2) [MIM:607636] Osteoporosis-pseudoglioma syndrome (OPPG) [MIM:259770] |
| LRP6 | O75581 | non-pleiotropic | Coronary artery disease, autosomal dominant, 2 (ADCAD2) [MIM:610947] |
| LRPPRC | P42704 | non-pleiotropic | Leigh syndrome French-Canadian type (LSFC) [MIM:220111] |
| LRRC6 | Q86X45 | non-pleiotropic | Ciliary dyskinesia, primary, 19 (CILD19) [MIM:614935] |
| LRRK2 | Q5S007 | non-pleiotropic | Parkinson disease 8 (PARK8) [MIM:607060] |
| LRTOMT | Q8WZ04 | non-pleiotropic | Deafness, autosomal recessive, 63 (DFNB63) [MIM:611451] |
| LTBP4 | Q8N2S1 | non-pleiotropic | Urban-Rifkin-Davis syndrome (URDS) [MIM:613177] |
| LYRM4 | Q9HD34 | non-pleiotropic | Combined oxidative phosphorylation deficiency 19 (COXPD19) [MIM:615595] |
| LYST | Q99698 | non-pleiotropic | Chediak-Higashi syndrome (CHS) [MIM:214500] |
| LYZ | P61626 | non-pleiotropic | Amyloidosis 8 (AMYL8) [MIM:105200] |
| LZTFL1 | Q9NQ48 | non-pleiotropic | Bardet-Biedl syndrome 17 (BBS17) [MIM:209900] |
| MAF | O75444 | non-pleiotropic | Cataract 21, multiple types (CTRCT21) [MIM:610202] |
| MAFB | Q9Y5Q3 | non-pleiotropic | Multicentric carpotarsal osteolysis syndrome (MCTO) [MIM:166300] |
| MAK | P20794 | non-pleiotropic | Retinitis pigmentosa 62 (RP62) [MIM:614181] |
| MALT1 | Q9UDY8 | non-pleiotropic | Immunodeficiency 12 (IMD12) [MIM:615468] |
| MAN1B1 | Q9UKM7 | non-pleiotropic | Mental retardation, autosomal recessive 15 (MRT15) [MIM:614202] |
| MAN2B1 | O00754 | non-pleiotropic | Mannosidosis, alpha B, lysosomal (MANSA) [MIM:248500] |
| MAP2K1 | Q02750 | non-pleiotropic | Cardiofaciocutaneous syndrome 3 (CFC3) [MIM:615279] |
| MAP2K2 | P36507 | non-pleiotropic | Cardiofaciocutaneous syndrome 4 (CFC4) [MIM:615280] |
| MAP3K1 | Q13233 | non-pleiotropic | 46,XY sex reversal 6 (SRXY6) [MIM:613762] |
| MAPK8IP1 | Q9UQF2 | non-pleiotropic | Diabetes mellitus, non-insulin-dependent (NIDDM) [MIM:125853] |
| MAPT | P10636 | pleiotropic | Pick disease of the brain (PIDB) [MIM:172700] Frontotemporal dementia (FTD) [MIM:600274] Progressive supranuclear palsy 1 (PSNP1) [MIM:601104] |
| MARS | P56192 | non-pleiotropic | Infantile liver failure syndrome 2 (ILFS2) [MIM:615486] |