Found 257 pleiotropic proteins (16.0 %) and 1345 non-pleiotropic proteins (84.0 %).
1602 items found (page 15 of 33)
Gene | UniProt | Protein Type | Disease |
---|---|---|---|
IL10RA | Q13651 | non-pleiotropic | Inflammatory bowel disease 28 (IBD28) [MIM:613148] |
IL11RA | Q14626 | non-pleiotropic | Craniosynostosis and dental anomalies (CRSDA) [MIM:614188] |
IL12RB1 | P42701 | non-pleiotropic | Mendelian susceptibility to mycobacterial disease (MSMD) [MIM:209950] |
IL17F | Q96PD4 | non-pleiotropic | Candidiasis, familial, 6 (CANDF6) [MIM:613956] |
IL17RD | Q8NFM7 | non-pleiotropic | Hypogonadotropic hypogonadism 18 with or without anosmia (HH18) [MIM:615267] |
IL31RA | Q8NI17 | non-pleiotropic | Amyloidosis, primary localized cutaneous, 2 (PLCA2) [MIM:613955] |
IL36RN | Q9UBH0 | non-pleiotropic | Psoriasis generalized pustular (PSORP) [MIM:614204] |
ILDR1 | Q86SU0 | non-pleiotropic | Deafness, autosomal recessive, 42 (DFNB42) [MIM:609646] |
IMPAD1 | Q9NX62 | non-pleiotropic | Chondrodysplasia with joint dislocations, GPAPP type (CDP-GPAPP) [MIM:614078] |
ING1 | Q9UK53 | non-pleiotropic | Squamous cell carcinoma of the head and neck (HNSCC) [MIM:275355] |
ING3 | Q9NXR8 | non-pleiotropic | Squamous cell carcinoma of the head and neck (HNSCC) [MIM:275355] |
INPPL1 | O15357 | non-pleiotropic | Opsismodysplasia (OPSMD) [MIM:258480] |
INS | P01308 | pleiotropic | Hyperproinsulinemia, familial (FHPRI) [MIM:176730] Maturity-onset diabetes of the young 10 (MODY10) [MIM:613370] Diabetes mellitus, permanent neonatal (PNDM) [MIM:606176] Diabetes mellitus, insulin-dependent, 2 (IDDM2) [MIM:125852] |
INSL3 | P51460 | non-pleiotropic | Cryptorchidism (CRYPTO) [MIM:219050] |
INSR | P06213 | pleiotropic | Rabson-Mendenhall syndrome (RMS) [MIM:262190] Leprechaunism (LEPRCH) [MIM:246200] Insulin-resistant diabetes mellitus with acanthosis nigricans type A (IRAN type A) [MIM:610549] Diabetes mellitus, non-insulin-dependent (NIDDM) [MIM:125853] Familial hyperinsulinemic hypoglycemia 5 (HHF5) [MIM:609968] |
INVS | Q9Y283 | non-pleiotropic | Nephronophthisis 2 (NPHP2) [MIM:602088] |
IQSEC2 | Q5JU85 | non-pleiotropic | Mental retardation, X-linked 1 (MRX1) [MIM:309530] |
IRF6 | O14896 | pleiotropic | Van der Woude syndrome 1 (VWS1) [MIM:119300] Popliteal pterygium syndrome (PPS) [MIM:119500] Non-syndromic orofacial cleft 6 (OFC6) [MIM:608864] |
IRS1 | P35568 | non-pleiotropic | Diabetes mellitus, non-insulin-dependent (NIDDM) [MIM:125853] |
IRX5 | P78411 | non-pleiotropic | Hamamy syndrome (HMMS) [MIM:611174] |
ISPD | A4D126 | non-pleiotropic | Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A7 (MDDGA7) [MIM:614643] |
ITGA3 | P26006 | non-pleiotropic | Interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital (ILNEB) [MIM:614748] |
ITGA8 | P53708 | non-pleiotropic | Renal hypodysplasia/aplasia 1 (RHDA1) [MIM:191830] |
ITGB2 | P05107 | non-pleiotropic | Leukocyte adhesion deficiency 1 (LAD1) [MIM:116920] |
ITK | Q08881 | non-pleiotropic | Lymphoproliferative syndrome 1 (LPFS1) [MIM:613011] |
ITPA | Q9BY32 | non-pleiotropic | Inosine triphosphate pyrophosphohydrolase deficiency (ITPAD) [MIM:613850] |
IVD | P26440 | non-pleiotropic | Isovaleric acidemia (IVA) [MIM:243500] |
IYD | Q6PHW0 | non-pleiotropic | Thyroid dyshormonogenesis 4 (TDH4) [MIM:274800] |
JAG1 | P78504 | pleiotropic | Alagille syndrome 1 (ALGS1) [MIM:118450] Tetralogy of Fallot (TOF) [MIM:187500] |
JAK2 | O60674 | pleiotropic | Leukemia, acute myelogenous (AML) [MIM:601626] Polycythemia vera (PV) [MIM:263300] Thrombocythemia 3 (THCYT3) [MIM:614521] |
JAM3 | Q9BX67 | non-pleiotropic | Hemorrhagic destruction of the brain with subependymal calcification and cataracts (HDBSCC) [MIM:613730] |
JPH2 | Q9BR39 | non-pleiotropic | Cardiomyopathy, familial hypertrophic 17 (CMH17) [MIM:613873] |
KAL1 | P23352 | non-pleiotropic | Hypogonadotropic hypogonadism 1 with or without anosmia (HH1) [MIM:308700] |
KARS | Q15046 | pleiotropic | Charcot-Marie-Tooth disease, recessive, intermediate type, B (CMTRIB) [MIM:613641] Deafness, autosomal recessive, 89 (DFNB89) [MIM:613916] |
KBTBD13 | C9JR72 | non-pleiotropic | Nemaline myopathy 6 (NEM6) [MIM:609273] |
KCNA1 | Q09470 | non-pleiotropic | Episodic ataxia 1 (EA1) [MIM:160120] Myokymia isolated 1 (MK1) [MIM:160120] |
KCNC3 | Q14003 | non-pleiotropic | Spinocerebellar ataxia 13 (SCA13) [MIM:605259] |
KCND3 | Q9UK17 | non-pleiotropic | Spinocerebellar ataxia 19 (SCA19) [MIM:607346] |
KCNE2 | Q9Y6J6 | pleiotropic | Long QT syndrome 6 (LQT6) [MIM:613693] Atrial fibrillation, familial, 4 (ATFB4) [MIM:611493] |
KCNE3 | Q9Y6H6 | non-pleiotropic | Brugada syndrome 6 (BRGDA6) [MIM:613119] |
KCNJ1 | P48048 | non-pleiotropic | Bartter syndrome 2 (BS2) [MIM:241200] |
KCNJ11 | Q14654 | pleiotropic | Familial hyperinsulinemic hypoglycemia 2 (HHF2) [MIM:601820] Diabetes mellitus, permanent neonatal (PNDM) [MIM:606176] Transient neonatal diabetes mellitus 3 (TNDM3) [MIM:610582] |
KCNJ18 | B7U540 | non-pleiotropic | Thyrotoxic periodic paralysis 2 (TTPP2) [MIM:613239] |
KCNJ2 | P63252 | pleiotropic | Long QT syndrome 7 (LQT7) [MIM:170390] Short QT syndrome 3 (SQT3) [MIM:609622] Atrial fibrillation, familial, 9 (ATFB9) [MIM:613980] |
KCNJ5 | P48544 | pleiotropic | Long QT syndrome 13 (LQT13) [MIM:613485] Familial hyperaldosteronism 3 (FH3) [MIM:613677] |
KCNJ8 | Q15842 | non-pleiotropic | Sudden infant death syndrome (SIDS) [MIM:272120] |
KCNK3 | O14649 | non-pleiotropic | Pulmonary hypertension, primary, 4 (PPH4) [MIM:615344] |
KCNK9 | Q9NPC2 | non-pleiotropic | Birk-Barel mental retardation dysmorphism syndrome (BIBAS) [MIM:612292] |
KCNMA1 | Q12791 | non-pleiotropic | Generalized epilepsy and paroxysmal dyskinesia (GEPD) [MIM:609446] |
KCNQ1 | P51787 | pleiotropic | Long QT syndrome 1 (LQT1) [MIM:192500] Jervell and Lange-Nielsen syndrome 1 (JLNS1) [MIM:220400] Atrial fibrillation, familial, 3 (ATFB3) [MIM:607554] Short QT syndrome 2 (SQT2) [MIM:609621] |