Phyre 2 Results for P60639

Email	l.a.kelley@imperial.ac.uk
Description	P60639
Date	Tue Jul 17 17:05:12 BST 2012
Unique Job ID	3be8ecaf5ed46f4e

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c2yvxD_

Top template information

PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte

Confidence and coverage

Confidence:

93.0%

Coverage:

62%

143 residues ( 62% of your sequence) have been modelled with 93.0% confidence by the single highest scoring template.

You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M N D Y V Q A L L M I L L T V V L Y Y F A K R L Q Q K Y P N P F L N P A L I A S L G I I F V L L I F G I S Y N G Y M K G

Secondary structure

SS confidence

Disorder ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence G S W I N H I L N A T V V C L A Y P L Y K N R E K I K D N V S I I F A S V L T G V M L N F M L V F L T L K A F G Y S K D

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence V I V T L L P R S I T A A V G I E V S H E L G G T D T M T V L F I I T T G L I G S I L G S M L L R F G R F E S S I A K G

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . .

Sequence L T Y G N A S H A F G T A K A L E M D I E S G A F S S I G M I L T A V I S S V L I P V L I L L F Y

Secondary structure

SS confidence

Disorder
? ?
? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 2yvx chain D

Region: 27 - 192
Aligned: 143
Modelled: 144
Confidence: 93.0%
Identity: 17%
PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte

Phyre2

PDB 2yvx chain A domain 3

Region: 27 - 174
Aligned: 125
Modelled: 126
Confidence: 56.5%
Identity: 18%
Fold: MgtE membrane domain-like
Superfamily: MgtE membrane domain-like
Family: MgtE membrane domain-like

Phyre2

PDB 3rfu chain C

Region: 25 - 110
Aligned: 86
Modelled: 86
Confidence: 24.0%
Identity: 17%
PDB header:hydrolase, membrane protein
Chain: C: PDB Molecule:copper efflux atpase;
PDBTitle: crystal structure of a copper-transporting pib-type atpase

Phyre2

PDB 3zv0 chain A

Region: 74 - 100
Aligned: 27
Modelled: 27
Confidence: 14.8%
Identity: 22%
PDB header:cell cycle
Chain: A: PDB Molecule:protein shq1;
PDBTitle: structure of the shq1p-cbf5p complex

Phyre2

PDB 1z0k chain B domain 1

Region: 78 - 91
Aligned: 14
Modelled: 14
Confidence: 14.3%
Identity: 21%
Fold: Long alpha-hairpin
Superfamily: Rabenosyn-5 Rab-binding domain-like
Family: Rabenosyn-5 Rab-binding domain-like

Phyre2

PDB 1yzm chain A domain 1

Region: 78 - 91
Aligned: 14
Modelled: 14
Confidence: 13.5%
Identity: 21%
Fold: Long alpha-hairpin
Superfamily: Rabenosyn-5 Rab-binding domain-like
Family: Rabenosyn-5 Rab-binding domain-like

Phyre2

PDB 1cii chain A

Region: 124 - 172
Aligned: 49
Modelled: 49
Confidence: 12.0%
Identity: 14%
PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia

Phyre2

PDB 1ckx chain A

Region: 49 - 58
Aligned: 10
Modelled: 10
Confidence: 7.9%
Identity: 60%
PDB header:metal transport
Chain: A: PDB Molecule:cystic fibrosis transmembrane conductance
PDBTitle: cystic fibrosis transmembrane conductance regulator:2 solution structures of peptides based on the phe508 region,3 the most common site of disease-causing delta-f508 mutation

Phyre2

PDB 2ks1 chain B

Region: 60 - 86
Aligned: 27
Modelled: 27
Confidence: 7.3%
Identity: 26%
PDB header:transferase
Chain: B: PDB Molecule:epidermal growth factor receptor;
PDBTitle: heterodimeric association of transmembrane domains of erbb1 and erbb22 receptors enabling kinase activation

Phyre2

PDB 3syj chain A

Region: 50 - 59
Aligned: 10
Modelled: 10
Confidence: 6.9%
Identity: 50%
PDB header:cell adhesion
Chain: A: PDB Molecule:adhesion and penetration protein autotransporter;
PDBTitle: crystal structure of the haemophilus influenzae hap adhesin

Phyre2

PDB 1l7v chain A

Region: 22 - 202
Aligned: 162
Modelled: 162
Confidence: 6.8%
Identity: 14%
Fold: ABC transporter involved in vitamin B12 uptake, BtuC
Superfamily: ABC transporter involved in vitamin B12 uptake, BtuC
Family: ABC transporter involved in vitamin B12 uptake, BtuC

Phyre2

PDB 2akz chain A domain 2

Region: 74 - 89
Aligned: 16
Modelled: 16
Confidence: 6.6%
Identity: 25%
Fold: Enolase N-terminal domain-like
Superfamily: Enolase N-terminal domain-like
Family: Enolase N-terminal domain-like

Phyre2

PDB 3p5n chain A

Region: 7 - 89
Aligned: 83
Modelled: 83
Confidence: 5.8%
Identity: 16%
PDB header:transport protein
Chain: A: PDB Molecule:riboflavin uptake protein;
PDBTitle: structure and mechanism of the s component of a bacterial ecf2 transporter

Phyre2

PDB 1ckw chain A

Region: 49 - 58
Aligned: 10
Modelled: 10
Confidence: 5.3%
Identity: 50%
PDB header:metal transport
Chain: A: PDB Molecule:protein (cystic fibrosis transmembrane
PDBTitle: cystic fibrosis transmembrane conductance regulator:2 solution structures of peptides based on the phe508 region,3 the most common site of disease-causing delta-f508 mutation

Phyre2

PDB 1uny chain A

Region: 163 - 180
Aligned: 18
Modelled: 18
Confidence: 5.2%
Identity: 28%
PDB header:four helix bundle
Chain: A: PDB Molecule:general control protein gcn4;
PDBTitle: structure based engineering of internal molecular surfaces2 of four helix bundles

Phyre2

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	N	D	Y	V	Q	A	L	L	M	I	L	L	T	V	V	L	Y	Y	F	A	K	R	L	Q	Q	K	Y	P	N	P	F	L	N	P	A	L	I	A	S	L	G	I	I	F	V	L	L	I	F	G	I	S	Y	N	G	Y	M	K	G
Secondary structure
SS confidence
Disorder	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	G	S	W	I	N	H	I	L	N	A	T	V	V	C	L	A	Y	P	L	Y	K	N	R	E	K	I	K	D	N	V	S	I	I	F	A	S	V	L	T	G	V	M	L	N	F	M	L	V	F	L	T	L	K	A	F	G	Y	S	K	D
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	V	I	V	T	L	L	P	R	S	I	T	A	A	V	G	I	E	V	S	H	E	L	G	G	T	D	T	M	T	V	L	F	I	I	T	T	G	L	I	G	S	I	L	G	S	M	L	L	R	F	G	R	F	E	S	S	I	A	K	G
Secondary structure
SS confidence
Disorder																						?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.
Sequence	L	T	Y	G	N	A	S	H	A	F	G	T	A	K	A	L	E	M	D	I	E	S	G	A	F	S	S	I	G	M	I	L	T	A	V	I	S	S	V	L	I	P	V	L	I	L	L	F	Y
Secondary structure
SS confidence
Disorder																				?	?																											?	?
Disorder confidence