Email l.a.kelley@imperial.ac.uk Description C6Y4D0 Date Sun Jul 8 11:45:10 BST 2012 Unique Job ID 715da638b24e05b9

Summary

Top model
Image coloured by rainbow N → C terminus Close Jmol	Model (left) based on template d1n1jb_ Top template information Fold:Histone-fold Superfamily:Histone-fold Family:TBP-associated factors, TAFs Confidence and coverage Confidence: 99.9% Coverage: 89% 77 residues ( 89% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template. 3D viewing Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1n1j chain B Region: 10 - 86 Aligned: 77 Modelled: 77 Confidence: 99.9% Identity: 35% Fold: Histone-fold Superfamily: Histone-fold Family: TBP-associated factors, TAFs Phyre2 PDB 1hio chain A Region: 6 - 87 Aligned: 82 Modelled: 82 Confidence: 99.8% Identity: 17% Fold: Histone-fold Superfamily: Histone-fold Family: Nucleosome core histones Phyre2 PDB 2byk chain A Region: 19 - 86 Aligned: 68 Modelled: 68 Confidence: 99.8% Identity: 31% PDB header:dna-binding protein Chain: A: PDB Molecule:chrac-16; PDBTitle: histone fold heterodimer of the chromatin accessibility2 complex Phyre2 PDB 2byk chain A domain 1 Region: 19 - 86 Aligned: 68 Modelled: 68 Confidence: 99.8% Identity: 31% Fold: Histone-fold Superfamily: Histone-fold Family: TBP-associated factors, TAFs Phyre2 PDB 2byk chain B domain 1 Region: 11 - 84 Aligned: 74 Modelled: 74 Confidence: 99.7% Identity: 23% Fold: Histone-fold Superfamily: Histone-fold Family: TBP-associated factors, TAFs Phyre2 PDB 2byk chain B Region: 11 - 84 Aligned: 74 Modelled: 74 Confidence: 99.7% Identity: 23% PDB header:dna-binding protein Chain: B: PDB Molecule:chrac-14; PDBTitle: histone fold heterodimer of the chromatin accessibility2 complex Phyre2 PDB 1jfi chain B Region: 7 - 84 Aligned: 78 Modelled: 78 Confidence: 99.7% Identity: 15% PDB header:transcription/dna Chain: B: PDB Molecule:transcription regulator nc2 beta chain; PDBTitle: crystal structure of the nc2-tbp-dna ternary complex Phyre2 PDB 1jfi chain B Region: 7 - 84 Aligned: 78 Modelled: 78 Confidence: 99.7% Identity: 15% Fold: Histone-fold Superfamily: Histone-fold Family: TBP-associated factors, TAFs Phyre2 PDB 1jfi chain A Region: 8 - 73 Aligned: 63 Modelled: 66 Confidence: 99.7% Identity: 27% Fold: Histone-fold Superfamily: Histone-fold Family: TBP-associated factors, TAFs Phyre2 PDB 1jfi chain A Region: 8 - 73 Aligned: 63 Modelled: 66 Confidence: 99.7% Identity: 27% PDB header:transcription/dna Chain: A: PDB Molecule:transcription regulator nc2 alpha chain; PDBTitle: crystal structure of the nc2-tbp-dna ternary complex Phyre2 PDB 1n1j chain A Region: 8 - 84 Aligned: 77 Modelled: 77 Confidence: 99.7% Identity: 19% Fold: Histone-fold Superfamily: Histone-fold Family: TBP-associated factors, TAFs Phyre2 PDB 1tzy chain A Region: 6 - 87 Aligned: 82 Modelled: 82 Confidence: 99.7% Identity: 17% Fold: Histone-fold Superfamily: Histone-fold Family: Nucleosome core histones Phyre2 PDB 1kx3 chain C Region: 6 - 87 Aligned: 82 Modelled: 82 Confidence: 99.7% Identity: 18% Fold: Histone-fold Superfamily: Histone-fold Family: Nucleosome core histones Phyre2 PDB 1f66 chain C Region: 6 - 86 Aligned: 81 Modelled: 81 Confidence: 99.7% Identity: 19% Fold: Histone-fold Superfamily: Histone-fold Family: Nucleosome core histones Phyre2 PDB 1f66 chain C Region: 6 - 86 Aligned: 81 Modelled: 81 Confidence: 99.7% Identity: 19% PDB header:structural protein/dna Chain: C: PDB Molecule:histone h2a.z; PDBTitle: 2.6 a crystal structure of a nucleosome core particle2 containing the variant histone h2a.z Phyre2 PDB 1aoi chain C Region: 6 - 87 Aligned: 82 Modelled: 82 Confidence: 99.7% Identity: 18% Fold: Histone-fold Superfamily: Histone-fold Family: Nucleosome core histones Phyre2 PDB 1u35 chain C domain 1 Region: 6 - 87 Aligned: 82 Modelled: 82 Confidence: 99.7% Identity: 17% Fold: Histone-fold Superfamily: Histone-fold Family: Nucleosome core histones Phyre2 PDB 2f8n chain K Region: 6 - 87 Aligned: 82 Modelled: 82 Confidence: 99.7% Identity: 17% PDB header:structural protein/dna Chain: K: PDB Molecule:histone h2a type 1; PDBTitle: 2.9 angstrom x-ray structure of hybrid macroh2a nucleosomes Phyre2 PDB 2bym chain A domain 1 Region: 26 - 86 Aligned: 61 Modelled: 61 Confidence: 99.7% Identity: 30% Fold: Histone-fold Superfamily: Histone-fold Family: TBP-associated factors, TAFs Phyre2 PDB 2jss chain A domain 1 Region: 6 - 85 Aligned: 80 Modelled: 80 Confidence: 99.6% Identity: 23% Fold: Histone-fold Superfamily: Histone-fold Family: Nucleosome core histones Phyre2 1 d1n1jb_ 2 d1hioa_ 3 c2bykA_ 4 d2byka1 5 d2bykb1 6 c2bykB_ 7 c1jfiB_ 8 d1jfib_ 9 d1jfia_ 10 c1jfiA_ 11 d1n1ja_ 12 d1tzya_ 13 d1kx3c_ 14 d1f66c_ 15 c1f66C_ 16 d1aoic_ 17 d1u35c1 18 c2f8nK_ 19 d2byma1 20 d2jssa1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0