Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionC6Y4B3
DateSun Jul 8 11:45:06 BST 2012
Unique Job ID7722aa44661935f5

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2rqxA_
Top template information
PDB header:signaling protein
Chain: A: PDB Molecule:polymyxin b resistance protein;
PDBTitle: solution nmr structure of pmrd from klebsiella pneumoniae
Confidence and coverage
Confidence: 30.3% Coverage: 25%
36 residues ( 25% of your sequence) have been modelled with 30.3% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MREFRLIFVLLFFLPSFAIANTEIINVETGDSNKLLTSNSVCDIELSNNSSIPLLLKPNP
Secondary structure 
























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Disorder  ????




















































?
?
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   .........70.........80.........90.........100.........110.........120
Sequence  TIPQAAGAPQQSKYTFSVCGLKPLQKYQIRASWPAVYPSDIILNYNITHIIVEINASFYS
Secondary structure 





















SS confidence 



























































Disorder  ???????????
















































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   .........130.........140..
Sequence  HNESLMKRPPLVPLRLGMFYRV
Secondary structure 






SS confidence 





















Disorder 

?


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????
??
Disorder confidence 





















 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2rqx chain A

3D model

Region: 88 - 123
Aligned: 36
Modelled: 36
Confidence: 30.3%
Identity: 31%
PDB header:signaling protein
Chain: A: PDB Molecule:polymyxin b resistance protein;
PDBTitle: solution nmr structure of pmrd from klebsiella pneumoniae

Phyre2

PDB 1jl6 chain A

3D model

Region: 80 - 100
Aligned: 21
Modelled: 21
Confidence: 18.5%
Identity: 29%
Fold: Globin-like
Superfamily: Globin-like
Family: Globins

Phyre2

PDB 1q8c chain A

3D model

Region: 7 - 18
Aligned: 12
Modelled: 12
Confidence: 15.8%
Identity: 75%
Fold: NusB-like
Superfamily: NusB-like
Family: Hypothetical protein MG027

Phyre2

PDB 3fvc chain A

3D model

Region: 70 - 81
Aligned: 12
Modelled: 12
Confidence: 15.2%
Identity: 50%
PDB header:viral protein
Chain: A: PDB Molecule:glycoprotein gp110;
PDBTitle: crystal structure of a trimeric variant of the epstein-barr virus2 glycoprotein b

Phyre2

PDB 1yhu chain X

3D model

Region: 80 - 99
Aligned: 20
Modelled: 20
Confidence: 12.5%
Identity: 10%
PDB header:oxygen storage/transport
Chain: X: PDB Molecule:hemoglobin b2 chain;
PDBTitle: crystal structure of riftia pachyptila c1 hemoglobin reveals novel2 assembly of 24 subunits.

Phyre2

PDB 1vpq chain A

3D model

Region: 111 - 120
Aligned: 10
Modelled: 10
Confidence: 11.9%
Identity: 50%
Fold: TIM beta/alpha-barrel
Superfamily: TM1631-like
Family: TM1631-like

Phyre2

PDB 1bqu chain A domain 2

3D model

Region: 70 - 90
Aligned: 21
Modelled: 21
Confidence: 11.6%
Identity: 33%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Fibronectin type III
Family: Fibronectin type III

Phyre2

PDB 3coo chain B

3D model

Region: 77 - 128
Aligned: 50
Modelled: 52
Confidence: 9.5%
Identity: 22%
PDB header:cell adhesion
Chain: B: PDB Molecule:spondin-1;
PDBTitle: the crystal structure of reelin-n domain of f-spondin

Phyre2

PDB 1wis chain A domain 1

3D model

Region: 72 - 92
Aligned: 21
Modelled: 21
Confidence: 9.3%
Identity: 24%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Fibronectin type III
Family: Fibronectin type III

Phyre2

PDB 1hds chain A

3D model

Region: 81 - 99
Aligned: 19
Modelled: 19
Confidence: 9.2%
Identity: 26%
Fold: Globin-like
Superfamily: Globin-like
Family: Globins

Phyre2

PDB 1jl7 chain A

3D model

Region: 80 - 100
Aligned: 21
Modelled: 21
Confidence: 8.9%
Identity: 24%
Fold: Globin-like
Superfamily: Globin-like
Family: Globins

Phyre2

PDB 2dtg chain E domain 3

3D model

Region: 72 - 90
Aligned: 19
Modelled: 19
Confidence: 8.5%
Identity: 32%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Fibronectin type III
Family: Fibronectin type III

Phyre2

PDB 1v5j chain A

3D model

Region: 72 - 90
Aligned: 19
Modelled: 19
Confidence: 8.2%
Identity: 26%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Fibronectin type III
Family: Fibronectin type III

Phyre2

PDB 1hbg chain A

3D model

Region: 80 - 100
Aligned: 21
Modelled: 21
Confidence: 8.1%
Identity: 33%
Fold: Globin-like
Superfamily: Globin-like
Family: Globins

Phyre2

PDB 3pmb chain A

3D model

Region: 79 - 84
Aligned: 6
Modelled: 6
Confidence: 8.0%
Identity: 83%
PDB header:hydrolase
Chain: A: PDB Molecule:thrombin light chain;
PDBTitle: 2.9 angstrom crystal structure of bovine thrombin in tetragonal2 spacegroup

Phyre2

PDB 2jso chain A

3D model

Region: 70 - 123
Aligned: 53
Modelled: 54
Confidence: 7.9%
Identity: 26%
PDB header:signaling protein
Chain: A: PDB Molecule:polymyxin resistance protein pmrd;
PDBTitle: antimicrobial resistance protein

Phyre2

PDB 1vpy chain A

3D model

Region: 111 - 120
Aligned: 10
Modelled: 10
Confidence: 7.8%
Identity: 30%
Fold: TIM beta/alpha-barrel
Superfamily: TM1631-like
Family: TM1631-like

Phyre2

PDB 1yhu chain J

3D model

Region: 83 - 99
Aligned: 17
Modelled: 17
Confidence: 7.8%
Identity: 35%
PDB header:oxygen storage/transport
Chain: J: PDB Molecule:giant hemoglobins b chain;
PDBTitle: crystal structure of riftia pachyptila c1 hemoglobin reveals novel2 assembly of 24 subunits.

Phyre2

PDB 3pt8 chain B

3D model

Region: 80 - 98
Aligned: 19
Modelled: 19
Confidence: 7.7%
Identity: 32%
PDB header:oxygen transport
Chain: B: PDB Molecule:hemoglobin iii;
PDBTitle: structure of hbii-iii-cn from lucina pectinata at ph 5.0

Phyre2

PDB 2lhb chain A

3D model

Region: 77 - 99
Aligned: 23
Modelled: 23
Confidence: 7.7%
Identity: 39%
Fold: Globin-like
Superfamily: Globin-like
Family: Globins

Phyre2
1

c2rqxA_
2

d1jl6a_
3

d1q8ca_
4

c3fvcA_
5

c1yhuX_
6

d1vpqa_
7

d1bqua2
8

c3cooB_
9

d1wisa1
10

d1hdsa_
11

d1jl7a_
12

d2dtge3
13

d1v5ja_
14

d1hbga_
15

c3pmbA_
16

c2jsoA_
17

d1vpya_
18

c1yhuJ_
19

c3pt8B_
20

d2lhba_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2rqxA_



30.3 31 PDB header:signaling protein
Chain: A: PDB Molecule:polymyxin b resistance protein;
PDBTitle: solution nmr structure of pmrd from klebsiella pneumoniae
2d1jl6a_



18.5 29 Fold:Globin-like
Superfamily:Globin-like
Family:Globins
3d1q8ca_



15.8 75 Fold:NusB-like
Superfamily:NusB-like
Family:Hypothetical protein MG027
4c3fvcA_



15.2 50 PDB header:viral protein
Chain: A: PDB Molecule:glycoprotein gp110;
PDBTitle: crystal structure of a trimeric variant of the epstein-barr virus2 glycoprotein b
5c1yhuX_



12.5 10 PDB header:oxygen storage/transport
Chain: X: PDB Molecule:hemoglobin b2 chain;
PDBTitle: crystal structure of riftia pachyptila c1 hemoglobin reveals novel2 assembly of 24 subunits.
6d1vpqa_



11.9 50 Fold:TIM beta/alpha-barrel
Superfamily:TM1631-like
Family:TM1631-like
7d1bqua2



11.6 33 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Fibronectin type III
Family:Fibronectin type III
8c3cooB_



9.5 22 PDB header:cell adhesion
Chain: B: PDB Molecule:spondin-1;
PDBTitle: the crystal structure of reelin-n domain of f-spondin
9d1wisa1



9.3 24 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Fibronectin type III
Family:Fibronectin type III
10d1hdsa_



9.2 26 Fold:Globin-like
Superfamily:Globin-like
Family:Globins
11d1jl7a_



8.9 24 Fold:Globin-like
Superfamily:Globin-like
Family:Globins
12d2dtge3



8.5 32 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Fibronectin type III
Family:Fibronectin type III
13d1v5ja_



8.2 26 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Fibronectin type III
Family:Fibronectin type III
14d1hbga_



8.1 33 Fold:Globin-like
Superfamily:Globin-like
Family:Globins
15c3pmbA_



8.0 83 PDB header:hydrolase
Chain: A: PDB Molecule:thrombin light chain;
PDBTitle: 2.9 angstrom crystal structure of bovine thrombin in tetragonal2 spacegroup
16c2jsoA_



7.9 26 PDB header:signaling protein
Chain: A: PDB Molecule:polymyxin resistance protein pmrd;
PDBTitle: antimicrobial resistance protein
17d1vpya_



7.8 30 Fold:TIM beta/alpha-barrel
Superfamily:TM1631-like
Family:TM1631-like
18c1yhuJ_



7.8 35 PDB header:oxygen storage/transport
Chain: J: PDB Molecule:giant hemoglobins b chain;
PDBTitle: crystal structure of riftia pachyptila c1 hemoglobin reveals novel2 assembly of 24 subunits.
19c3pt8B_



7.7 32 PDB header:oxygen transport
Chain: B: PDB Molecule:hemoglobin iii;
PDBTitle: structure of hbii-iii-cn from lucina pectinata at ph 5.0
20d2lhba_



7.7 39 Fold:Globin-like
Superfamily:Globin-like
Family:Globins
21d1tena_



not modelled 7.1 26 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Fibronectin type III
Family:Fibronectin type III
22d2d9qb2



not modelled 6.8 24 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Fibronectin type III
Family:Fibronectin type III
23c2r2mA_



not modelled 6.7 83 PDB header:hydrolase/hydrolase inhibitor
Chain: A: PDB Molecule:thrombin light chain;
PDBTitle: 2-(2-chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors
24c1t4uL_



not modelled 6.7 83 PDB header:hydrolase/hydrolase inhibitor
Chain: L: PDB Molecule:prothrombin;
PDBTitle: crystal structure analysis of a novel oxyguanidine bound to thrombin
25c3c27A_



not modelled 6.7 83 PDB header:hydrolase/hydrolase inhibitor
Chain: A: PDB Molecule:thrombin light chain;
PDBTitle: cyanofluorophenylacetamides as orally efficacious thrombin inhibitors
26c1t4vL_



not modelled 6.7 83 PDB header:hydrolase/hydrolase inhibitor
Chain: L: PDB Molecule:prothrombin;
PDBTitle: crystal structure analysis of a novel oxyguanidine bound to thrombin
27d1d8ua_



not modelled 6.7 16 Fold:Globin-like
Superfamily:Globin-like
Family:Globins
28c1p8vB_



not modelled 6.3 83 PDB header:membrane protein/hydrolase
Chain: B: PDB Molecule:prothrombin;
PDBTitle: crystal structure of the complex of platelet receptor gpib-alpha and2 alpha-thrombin at 2.6a
29c2vy8A_



not modelled 6.3 35 PDB header:transcription
Chain: A: PDB Molecule:polymerase basic protein 2;
PDBTitle: the 627-domain from influenza a virus polymerase pb22 subunit with glu-627
30d1p9ma3



not modelled 6.2 33 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Fibronectin type III
Family:Fibronectin type III
31c2bbdA_



not modelled 6.2 45 PDB header:viral protein
Chain: A: PDB Molecule:coat protein;
PDBTitle: crystal structure of the stiv mcp
32c2ajwA_



not modelled 6.1 64 PDB header:toxin
Chain: A: PDB Molecule:alpha-conotoxin mii;
PDBTitle: structure of the cyclic conotoxin mii-6
33d1v4wa_



not modelled 5.9 25 Fold:Globin-like
Superfamily:Globin-like
Family:Globins
34d1bpva_



not modelled 5.9 38 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Fibronectin type III
Family:Fibronectin type III
35c1o1nA_



not modelled 5.8 30 PDB header:oxygen storage/transport
Chain: A: PDB Molecule:hemoglobin alpha chain;
PDBTitle: deoxy hemoglobin (a-glyglygly-c:v1m,l29w; b,d:v1m)
36c2ck2B_



not modelled 5.7 42 PDB header:signaling protein
Chain: B: PDB Molecule:human fibronectin;
PDBTitle: structure of core-swapped mutant of fibronectin
37c3mvcB_



not modelled 5.5 19 PDB header:electron transport
Chain: B: PDB Molecule:globin protein 6;
PDBTitle: high resolution crystal structure of the heme domain of glb-6 from c.2 elegans
38d2dn3b1



not modelled 5.5 29 Fold:Globin-like
Superfamily:Globin-like
Family:Globins
39c3h8hA_



not modelled 5.5 38 PDB header:transcription
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase ring2;
PDBTitle: structure of the c-terminal domain of human rnf2/ring1b;
40c1x3kA_



not modelled 5.2 21 PDB header:oxygen storage/transport
Chain: A: PDB Molecule:hemoglobin component v;
PDBTitle: crystal structure of a hemoglobin component (ta-v) from2 tokunagayusurika akamusi
41d1spgb_



not modelled 5.2 18 Fold:Globin-like
Superfamily:Globin-like
Family:Globins

Binding site prediction 

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If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite