Phyre 2 Results for A1A4F0

Email	l.a.kelley@imperial.ac.uk
Description	A1A4F0
Date	Tue Apr 3 15:02:45 BST 2012
Unique Job ID	4319bedaf065a33c

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template d1r7ma2

Top template information

Fold:Homing endonuclease-like
Superfamily:Homing endonucleases
Family:Group I mobile intron endonuclease

Confidence and coverage

Confidence:

34.8%

Coverage:

10%

13 residues ( 10% of your sequence) have been modelled with 34.8% confidence by the single highest scoring template.

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3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M K V V G N Y R V N T A N S S T D T S G E H L T C L R S Q L F V A Y R N G R V D E A V S L G F L D C W I G G D L T N F K

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ?
? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence G C Y L T N Q L P I Q I F T A I F D M N T D V I I L S Q F M Y Y R L K N Q K K K M I F Q P Q L F K D S I T R E K V R L S

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . .

Sequence L W G V L C P V Y I P Y S F R

Secondary structure

SS confidence

Disorder
? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 1r7m chain A domain 2

Region: 43 - 55
Aligned: 13
Modelled: 13
Confidence: 34.8%
Identity: 23%
Fold: Homing endonuclease-like
Superfamily: Homing endonucleases
Family: Group I mobile intron endonuclease

Phyre2

PDB 1r7m chain A

Region: 43 - 55
Aligned: 13
Modelled: 13
Confidence: 30.8%
Identity: 23%
PDB header:hydrolase/dna
Chain: A: PDB Molecule:intron-encoded endonuclease i-scei;
PDBTitle: the homing endonuclease i-scei bound to its dna recognition2 region

Phyre2

PDB 2l35 chain B

Region: 42 - 79
Aligned: 28
Modelled: 38
Confidence: 16.5%
Identity: 36%
PDB header:protein binding
Chain: B: PDB Molecule:tyro protein tyrosine kinase-binding protein;
PDBTitle: structure of the dap12-nkg2c transmembrane heterotrimer

Phyre2

PDB 2l34 chain B

Region: 42 - 79
Aligned: 28
Modelled: 38
Confidence: 16.1%
Identity: 36%
PDB header:protein binding
Chain: B: PDB Molecule:tyro protein tyrosine kinase-binding protein;
PDBTitle: structure of the dap12 transmembrane homodimer

Phyre2

PDB 2l34 chain A

Region: 42 - 79
Aligned: 28
Modelled: 38
Confidence: 16.1%
Identity: 36%
PDB header:protein binding
Chain: A: PDB Molecule:tyro protein tyrosine kinase-binding protein;
PDBTitle: structure of the dap12 transmembrane homodimer

Phyre2

PDB 1gnw chain A domain 1

Region: 78 - 124
Aligned: 46
Modelled: 47
Confidence: 10.8%
Identity: 17%
Fold: GST C-terminal domain-like
Superfamily: GST C-terminal domain-like
Family: Glutathione S-transferase (GST), C-terminal domain

Phyre2

PDB 1pw4 chain A

Region: 20 - 105
Aligned: 86
Modelled: 86
Confidence: 9.7%
Identity: 7%
Fold: MFS general substrate transporter
Superfamily: MFS general substrate transporter
Family: Glycerol-3-phosphate transporter

Phyre2

PDB 2uz8 chain A

Region: 78 - 125
Aligned: 47
Modelled: 48
Confidence: 9.0%
Identity: 4%
PDB header:rna-binding protein
Chain: A: PDB Molecule:eukaryotic translation elongation factor 1
PDBTitle: the crystal structure of p18, human translation elongation2 factor 1 epsilon 1

Phyre2

PDB 3iyd chain C

Region: 119 - 131
Aligned: 13
Modelled: 13
Confidence: 8.7%
Identity: 31%
PDB header:transcription/dna
Chain: C: PDB Molecule:dna-directed rna polymerase subunit beta;
PDBTitle: three-dimensional em structure of an intact activator-dependent2 transcription initiation complex

Phyre2

PDB 1axd chain A domain 1

Region: 78 - 125
Aligned: 47
Modelled: 48
Confidence: 8.7%
Identity: 15%
Fold: GST C-terminal domain-like
Superfamily: GST C-terminal domain-like
Family: Glutathione S-transferase (GST), C-terminal domain

Phyre2

PDB 1nhy chain A domain 1

Region: 78 - 125
Aligned: 48
Modelled: 48
Confidence: 8.6%
Identity: 13%
Fold: GST C-terminal domain-like
Superfamily: GST C-terminal domain-like
Family: Glutathione S-transferase (GST), C-terminal domain

Phyre2

PDB 3qag chain A

Region: 78 - 125
Aligned: 47
Modelled: 48
Confidence: 7.8%
Identity: 15%
PDB header:transferase
Chain: A: PDB Molecule:glutathione s-transferase omega-2;
PDBTitle: human glutathione transferase o2 with glutathione -new crystal form

Phyre2

PDB 2rdd chain B

Region: 83 - 109
Aligned: 27
Modelled: 27
Confidence: 7.1%
Identity: 22%
PDB header:membrane protein/transport protein
Chain: B: PDB Molecule:upf0092 membrane protein yajc;
PDBTitle: x-ray crystal structure of acrb in complex with a novel2 transmembrane helix.

Phyre2

PDB 2l35 chain A

Region: 59 - 79
Aligned: 21
Modelled: 21
Confidence: 6.0%
Identity: 19%
PDB header:protein binding
Chain: A: PDB Molecule:dap12-nkg2c_tm;
PDBTitle: structure of the dap12-nkg2c transmembrane heterotrimer

Phyre2

PDB 1aw9 chain A domain 1

Region: 78 - 131
Aligned: 53
Modelled: 54
Confidence: 5.7%
Identity: 13%
Fold: GST C-terminal domain-like
Superfamily: GST C-terminal domain-like
Family: Glutathione S-transferase (GST), C-terminal domain

Phyre2

PDB 2w3c chain A

Region: 45 - 116
Aligned: 71
Modelled: 72
Confidence: 5.6%
Identity: 18%
PDB header:transport protein
Chain: A: PDB Molecule:general vesicular transport factor p115;
PDBTitle: globular head region of the human general vesicular2 transport factor p115

Phyre2

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	K	V	V	G	N	Y	R	V	N	T	A	N	S	S	T	D	T	S	G	E	H	L	T	C	L	R	S	Q	L	F	V	A	Y	R	N	G	R	V	D	E	A	V	S	L	G	F	L	D	C	W	I	G	G	D	L	T	N	F	K
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?		?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	G	C	Y	L	T	N	Q	L	P	I	Q	I	F	T	A	I	F	D	M	N	T	D	V	I	I	L	S	Q	F	M	Y	Y	R	L	K	N	Q	K	K	K	M	I	F	Q	P	Q	L	F	K	D	S	I	T	R	E	K	V	R	L	S
Secondary structure
SS confidence
Disorder																																			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.
Sequence	L	W	G	V	L	C	P	V	Y	I	P	Y	S	F	R
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?
Disorder confidence