Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP37642
DateThu Jan 5 11:56:15 GMT 2012
Unique Job IDfebf7fdef236c31f

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d2r6gf1
Top template information
Fold:MalF N-terminal region-like
Superfamily:MalF N-terminal region-like
Family:MalF N-terminal region-like
Confidence and coverage
Confidence: 84.2% Coverage: 23%
77 residues ( 23% of your sequence) have been modelled with 84.2% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTQENEIKRPIQDLEHEPIKPLDNSEKGSKVSQALETVTTTAEKVQRQPVIAHLIRATER
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Disorder  ???????????

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   .........70.........80.........90.........100.........110.........120
Sequence  FNDRLGNQFGAAITYFSFLSMIPILMVSFAAGGFVLASHPMLLQDIFDKILQNISDPTLA
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   .........130.........140.........150.........160.........170.........180
Sequence  ATLKNTINTAVQQRTTVGLVGLAVALYSGINWMGNLREAIRAQSRDVWERSPQDQEKFWV
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   .........190.........200.........210.........220.........230.........240
Sequence  KYLRDFISLIGLLIALIVTLSITSVAGSAQQMIISALHLNSIEWLKPTWRLIGLAISIFA
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   .........250.........260.........270.........280.........290.........300
Sequence  NYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGFEVIKIVMTYTLPSLMKSPSGAAFGSVL
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   .........310.........320.........330.......
Sequence  GLMAFFYFFARLTLFCAAWIATAEYKDDPRMPGKTQP
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????????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2r6g chain F domain 1

3D model

Region: 212 - 289
Aligned: 77
Modelled: 78
Confidence: 84.2%
Identity: 12%
Fold: MalF N-terminal region-like
Superfamily: MalF N-terminal region-like
Family: MalF N-terminal region-like

Phyre2

PDB 2qks chain A

3D model

Region: 226 - 313
Aligned: 88
Modelled: 88
Confidence: 41.0%
Identity: 10%
PDB header:metal transport
Chain: A: PDB Molecule:kir3.1-prokaryotic kir channel chimera;
PDBTitle: crystal structure of a kir3.1-prokaryotic kir channel chimera

Phyre2

PDB 1m8l chain A

3D model

Region: 17 - 79
Aligned: 63
Modelled: 63
Confidence: 32.7%
Identity: 13%
PDB header:viral protein
Chain: A: PDB Molecule:vpr protein;
PDBTitle: nmr structure of the hiv-1 regulatory protein vpr

Phyre2

PDB 1xl6 chain B

3D model

Region: 226 - 313
Aligned: 88
Modelled: 88
Confidence: 29.7%
Identity: 6%
PDB header:metal transport
Chain: B: PDB Molecule:inward rectifier potassium channel;
PDBTitle: intermediate gating structure 2 of the inwardly rectifying k+ channel2 kirbac3.1

Phyre2

PDB 3dh4 chain A

3D model

Region: 63 - 278
Aligned: 211
Modelled: 216
Confidence: 21.5%
Identity: 15%
PDB header:transport protein
Chain: A: PDB Molecule:sodium/glucose cotransporter;
PDBTitle: crystal structure of sodium/sugar symporter with bound galactose from2 vibrio parahaemolyticus

Phyre2

PDB 3hie chain A

3D model

Region: 9 - 35
Aligned: 27
Modelled: 27
Confidence: 14.5%
Identity: 26%
PDB header:exocytosis
Chain: A: PDB Molecule:exocyst complex component sec3;
PDBTitle: structure of the membrane-binding domain of the sec3 subunit2 of the exocyst complex

Phyre2

PDB 1w8x chain P

3D model

Region: 292 - 308
Aligned: 17
Modelled: 17
Confidence: 11.1%
Identity: 12%
PDB header:virus
Chain: P: PDB Molecule:protein p16;
PDBTitle: structural analysis of prd1

Phyre2

PDB 3a58 chain A

3D model

Region: 9 - 35
Aligned: 27
Modelled: 27
Confidence: 9.9%
Identity: 26%
PDB header:protein transport/exocytosis
Chain: A: PDB Molecule:exocyst complex component sec3;
PDBTitle: crystal structure of sec3p - rho1p complex from2 saccharomyces cerevisiae

Phyre2

PDB 1bh9 chain B

3D model

Region: 28 - 65
Aligned: 36
Modelled: 38
Confidence: 8.0%
Identity: 28%
Fold: Histone-fold
Superfamily: Histone-fold
Family: TBP-associated factors, TAFs

Phyre2

PDB 3gqn chain A

3D model

Region: 7 - 30
Aligned: 24
Modelled: 24
Confidence: 6.2%
Identity: 21%
PDB header:viral protein
Chain: A: PDB Molecule:preneck appendage protein;
PDBTitle: crystal structure of the pre-mature bacteriophage phi29 gene product2 12

Phyre2

PDB 1bm4 chain A

3D model

Region: 36 - 61
Aligned: 26
Modelled: 26
Confidence: 5.9%
Identity: 19%
PDB header:viral protein
Chain: A: PDB Molecule:protein (moloney murine leukemia virus capsid);
PDBTitle: momlv capsid protein major homology region peptide analog

Phyre2

PDB 2xl1 chain A

3D model

Region: 52 - 68
Aligned: 17
Modelled: 9
Confidence: 5.2%
Identity: 24%
PDB header:translation
Chain: A: PDB Molecule:arginine attenuator peptide;
PDBTitle: structural basis of translational stalling by human cytomegalovirus2 (hcmv) and fungal arginine attenuator peptide (aap)

Phyre2

PDB 3ixz chain B

3D model

Region: 220 - 261
Aligned: 42
Modelled: 42
Confidence: 5.1%
Identity: 7%
PDB header:hydrolase
Chain: B: PDB Molecule:potassium-transporting atpase subunit beta;
PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride

Phyre2
1

d2r6gf1
2

c2qksA_
3

c1m8lA_
4

c1xl6B_
5

c3dh4A_
6

c3hieA_
7

c1w8xP_
8

c3a58A_
9

d1bh9b_
10

c3gqnA_
11

c1bm4A_
12

c2xl1A_
13

c3ixzB_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d2r6gf1



84.2 12 Fold:MalF N-terminal region-like
Superfamily:MalF N-terminal region-like
Family:MalF N-terminal region-like
2c2qksA_



41.0 10 PDB header:metal transport
Chain: A: PDB Molecule:kir3.1-prokaryotic kir channel chimera;
PDBTitle: crystal structure of a kir3.1-prokaryotic kir channel chimera
3c1m8lA_



32.7 13 PDB header:viral protein
Chain: A: PDB Molecule:vpr protein;
PDBTitle: nmr structure of the hiv-1 regulatory protein vpr
4c1xl6B_



29.7 6 PDB header:metal transport
Chain: B: PDB Molecule:inward rectifier potassium channel;
PDBTitle: intermediate gating structure 2 of the inwardly rectifying k+ channel2 kirbac3.1
5c3dh4A_



21.5 15 PDB header:transport protein
Chain: A: PDB Molecule:sodium/glucose cotransporter;
PDBTitle: crystal structure of sodium/sugar symporter with bound galactose from2 vibrio parahaemolyticus
6c3hieA_



14.5 26 PDB header:exocytosis
Chain: A: PDB Molecule:exocyst complex component sec3;
PDBTitle: structure of the membrane-binding domain of the sec3 subunit2 of the exocyst complex
7c1w8xP_



11.1 12 PDB header:virus
Chain: P: PDB Molecule:protein p16;
PDBTitle: structural analysis of prd1
8c3a58A_



9.9 26 PDB header:protein transport/exocytosis
Chain: A: PDB Molecule:exocyst complex component sec3;
PDBTitle: crystal structure of sec3p - rho1p complex from2 saccharomyces cerevisiae
9d1bh9b_



8.0 28 Fold:Histone-fold
Superfamily:Histone-fold
Family:TBP-associated factors, TAFs
10c3gqnA_



6.2 21 PDB header:viral protein
Chain: A: PDB Molecule:preneck appendage protein;
PDBTitle: crystal structure of the pre-mature bacteriophage phi29 gene product2 12
11c1bm4A_



5.9 19 PDB header:viral protein
Chain: A: PDB Molecule:protein (moloney murine leukemia virus capsid);
PDBTitle: momlv capsid protein major homology region peptide analog
12c2xl1A_



5.2 24 PDB header:translation
Chain: A: PDB Molecule:arginine attenuator peptide;
PDBTitle: structural basis of translational stalling by human cytomegalovirus2 (hcmv) and fungal arginine attenuator peptide (aap)
13c3ixzB_



5.1 7 PDB header:hydrolase
Chain: B: PDB Molecule:potassium-transporting atpase subunit beta;
PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0