Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	M	P	R	I	K	P	L	L	V	L	C	A	A	L	L	T	V	T	P	A	A	S	A	D	V	N	S	D	M	N	Q	F	F	N	K	L	G	F	A	S	N	T	T	Q	P	G	V	W	Q	G	Q	A	A	G	Y	A	Y	G	G
Secondary structure
SS confidence
Disorder		?	?	?	?														?	?	?	?	?	?	?	?												?		?	?	?	?	?	?	?	?	?	?	?	?		?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	L	Y	A	R	T	Q	V	K	N	V	Q	L	I	S	M	T	L	P	D	I	N	A	G	C	G	G	I	D	A	Y	L	G	S	F	S	F	I	N	G	E	Q	L	Q	R	F	V	K	Q	I	M	S	N	A	A	G	Y	F	F	D
Secondary structure
SS confidence
Disorder																		?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	A	L	Q	T	T	V	P	E	I	K	T	A	K	D	F	L	Q	K	M	A	S	D	I	N	S	M	N	L	S	S	C	Q	A	A	Q	G	I	I	G	G	L	F	P	R	T	Q	V	S	Q	Q	K	V	C	Q	D	I	A	G	E
Secondary structure
SS confidence
Disorder																																											?	?	?	?												?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	N	I	F	A	D	W	A	A	S	R	Q	G	C	T	V	G	G	K	S	D	S	V	R	D	K	A	S	D	K	D	K	E	R	V	T	K	N	I	N	I	M	W	N	A	L	S	K	N	R	M	F	D	G	N	K	E	L	K	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?	?										?	?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		F	V	M	T	L	T	G	S	L	V	F	G	P	N	G	E	I	T	P	L	S	A	R	T	T	D	R	S	I	I	R	A	M	M	E	G	G	T	A	K	I	S	H	C	N	D	S	D	K	C	L	K	V	V	A	D	T	P	V	T
Secondary structure
SS confidence
Disorder																		?		?					?		?																													?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		I	S	R	D	N	A	L	K	S	Q	I	T	K	L	L	A	S	I	Q	N	K	A	V	S	D	T	P	L	D	D	K	E	K	G	F	I	S	S	T	T	I	P	V	F	K	Y	L	V	D	P	Q	M	L	G	V	S	N	S	M	I
Secondary structure
SS confidence
Disorder		?	?	?																			?		?			?										?			?	?	?											?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		Y	Q	L	T	D	Y	I	G	Y	D	I	L	L	Q	Y	I	Q	E	L	I	Q	Q	A	R	A	M	V	A	T	G	N	Y	D	E	A	V	I	G	H	I	N	D	N	M	N	D	A	T	R	Q	I	A	A	F	Q	S	Q	V	Q	V
Secondary structure
SS confidence
Disorder																													?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.
Sequence		Q	Q	D	A	L	L	V	V	D	R	Q	M	S	Y	M	R	Q	Q	L	S	A	R	M	L	S	R	Y	Q	N	N	Y	H	F	G	G	S	T	L
Secondary structure
SS confidence
Disorder																							?	?	?									?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1z6n chain A domain 1 Region: 125 - 149 Aligned: 25 Modelled: 25 Confidence: 41.0% Identity: 12% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 3pwx chain B Region: 2 - 147 Aligned: 125 Modelled: 133 Confidence: 36.0% Identity: 11% PDB header:structural protein Chain: B: PDB Molecule:putative flagellar hook-associated protein; PDBTitle: structure of putative flagellar hook-associated protein from vibrio2 parahaemolyticus Phyre2 PDB 2kuj chain A Region: 83 - 90 Aligned: 8 Modelled: 8 Confidence: 32.3% Identity: 75% PDB header:antimicrobial protein Chain: A: PDB Molecule:acanthaporin; PDBTitle: the solution structure of the dimeric acanthaporin Phyre2 PDB 2f8a chain A domain 1 Region: 125 - 146 Aligned: 22 Modelled: 22 Confidence: 28.7% Identity: 0% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Glutathione peroxidase-like Phyre2 PDB 1mqs chain A Region: 84 - 114 Aligned: 31 Modelled: 31 Confidence: 25.9% Identity: 6% Fold: Sec1/munc18-like (SM) proteins Superfamily: Sec1/munc18-like (SM) proteins Family: Sec1/munc18-like (SM) proteins Phyre2 PDB 2he3 chain A Region: 125 - 146 Aligned: 22 Modelled: 22 Confidence: 21.4% Identity: 5% PDB header:oxidoreductase Chain: A: PDB Molecule:glutathione peroxidase 2; PDBTitle: crystal structure of the selenocysteine to cysteine mutant of human2 glutathionine peroxidase 2 (gpx2) Phyre2 PDB 1fui chain A domain 1 Region: 46 - 86 Aligned: 41 Modelled: 41 Confidence: 21.3% Identity: 24% Fold: Reductase/isomerase/elongation factor common domain Superfamily: FucI/AraA C-terminal domain-like Family: L-fucose isomerase, C-terminal domain Phyre2 PDB 1v9w chain A Region: 125 - 143 Aligned: 19 Modelled: 19 Confidence: 19.7% Identity: 11% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Txnl5-like Phyre2 PDB 1udx chain A domain 1 Region: 59 - 87 Aligned: 29 Modelled: 29 Confidence: 19.7% Identity: 28% Fold: Obg-fold Superfamily: Obg GTP-binding protein N-terminal domain Family: Obg GTP-binding protein N-terminal domain Phyre2 PDB 2ehh chain E Region: 81 - 116 Aligned: 36 Modelled: 36 Confidence: 18.8% Identity: 19% PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus Phyre2 PDB 1lnz chain A domain 1 Region: 59 - 87 Aligned: 29 Modelled: 29 Confidence: 18.7% Identity: 17% Fold: Obg-fold Superfamily: Obg GTP-binding protein N-terminal domain Family: Obg GTP-binding protein N-terminal domain Phyre2 PDB 3emx chain B Region: 125 - 145 Aligned: 21 Modelled: 21 Confidence: 18.0% Identity: 14% PDB header:oxidoreductase Chain: B: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from aeropyrum pernix Phyre2 PDB 2c49 chain A Region: 56 - 97 Aligned: 34 Modelled: 42 Confidence: 17.7% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:sugar kinase mj0406; PDBTitle: crystal structure of methanocaldococcus jannaschii2 nucleoside kinase - an archaeal member of the ribokinase3 family Phyre2 PDB 2hyx chain A Region: 125 - 144 Aligned: 20 Modelled: 20 Confidence: 17.7% Identity: 5% PDB header:unknown function Chain: A: PDB Molecule:protein dipz; PDBTitle: structure of the c-terminal domain of dipz from mycobacterium2 tuberculosis Phyre2 PDB 1m3v chain A domain 1 Region: 78 - 87 Aligned: 10 Modelled: 10 Confidence: 17.5% Identity: 50% Fold: Glucocorticoid receptor-like (DNA-binding domain) Superfamily: Glucocorticoid receptor-like (DNA-binding domain) Family: LIM domain Phyre2 PDB 2j9g chain A domain 2 Region: 96 - 119 Aligned: 24 Modelled: 24 Confidence: 17.0% Identity: 25% Fold: PreATP-grasp domain Superfamily: PreATP-grasp domain Family: BC N-terminal domain-like Phyre2 PDB 2b5e chain A domain 1 Region: 125 - 150 Aligned: 26 Modelled: 26 Confidence: 16.0% Identity: 12% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: PDI-like Phyre2 PDB 1ulz chain A domain 2 Region: 96 - 119 Aligned: 24 Modelled: 24 Confidence: 15.8% Identity: 21% Fold: PreATP-grasp domain Superfamily: PreATP-grasp domain Family: BC N-terminal domain-like Phyre2 PDB 1w96 chain A domain 2 Region: 96 - 119 Aligned: 24 Modelled: 24 Confidence: 15.7% Identity: 17% Fold: PreATP-grasp domain Superfamily: PreATP-grasp domain Family: BC N-terminal domain-like Phyre2 PDB 1wou chain A Region: 125 - 142 Aligned: 18 Modelled: 18 Confidence: 15.2% Identity: 11% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Txnl5-like Phyre2 1 d1z6na1 2 c3pwxB_ 3 c2kujA_ 4 d2f8aa1 5 d1mqsa_ 6 c2he3A_ 7 d1fuia1 8 d1v9wa_ 9 d1udxa1 10 c2ehhE_ 11 d1lnza1 12 c3emxB_ 13 c2c49A_ 14 c2hyxA_ 15 d1m3va1 16 d2j9ga2 17 d2b5ea1 18 d1ulza2 19 d1w96a2 20 d1woua_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1z6na1 41.0 12 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 2 c3pwxB_ 36.0 11 PDB header:structural protein Chain: B: PDB Molecule:putative flagellar hook-associated protein; PDBTitle: structure of putative flagellar hook-associated protein from vibrio2 parahaemolyticus 3 c2kujA_ 32.3 75 PDB header:antimicrobial protein Chain: A: PDB Molecule:acanthaporin; PDBTitle: the solution structure of the dimeric acanthaporin 4 d2f8aa1 28.7 0 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 5 d1mqsa_ 25.9 6 Fold:Sec1/munc18-like (SM) proteins Superfamily:Sec1/munc18-like (SM) proteins Family:Sec1/munc18-like (SM) proteins 6 c2he3A_ 21.4 5 PDB header:oxidoreductase Chain: A: PDB Molecule:glutathione peroxidase 2; PDBTitle: crystal structure of the selenocysteine to cysteine mutant of human2 glutathionine peroxidase 2 (gpx2) 7 d1fuia1 21.3 24 Fold:Reductase/isomerase/elongation factor common domain Superfamily:FucI/AraA C-terminal domain-like Family:L-fucose isomerase, C-terminal domain 8 d1v9wa_ 19.7 11 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Txnl5-like 9 d1udxa1 19.7 28 Fold:Obg-fold Superfamily:Obg GTP-binding protein N-terminal domain Family:Obg GTP-binding protein N-terminal domain 10 c2ehhE_ 18.8 19 PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus 11 d1lnza1 18.7 17 Fold:Obg-fold Superfamily:Obg GTP-binding protein N-terminal domain Family:Obg GTP-binding protein N-terminal domain 12 c3emxB_ 18.0 14 PDB header:oxidoreductase Chain: B: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from aeropyrum pernix 13 c2c49A_ 17.7 26 PDB header:transferase Chain: A: PDB Molecule:sugar kinase mj0406; PDBTitle: crystal structure of methanocaldococcus jannaschii2 nucleoside kinase - an archaeal member of the ribokinase3 family 14 c2hyxA_ 17.7 5 PDB header:unknown function Chain: A: PDB Molecule:protein dipz; PDBTitle: structure of the c-terminal domain of dipz from mycobacterium2 tuberculosis 15 d1m3va1 17.5 50 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:LIM domain 16 d2j9ga2 17.0 25 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 17 d2b5ea1 16.0 12 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 18 d1ulza2 15.8 21 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 19 d1w96a2 15.7 17 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 20 d1woua_ 15.2 11 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Txnl5-like 21 c3qdnA_ not modelled 14.8 9 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin protein; PDBTitle: putative thioredoxin protein from salmonella typhimurium 22 c3bf5A_ not modelled 14.6 11 PDB header:transferase Chain: A: PDB Molecule:ribokinase related protein; PDBTitle: crystal structure of putative ribokinase (10640157) from thermoplasma2 acidophilum at 1.91 a resolution 23 c3b1qD_ not modelled 14.1 29 PDB header:transferase Chain: D: PDB Molecule:ribokinase, putative; PDBTitle: structure of burkholderia thailandensis nucleoside kinase (bthnk) in2 complex with inosine 24 d1epua_ not modelled 13.8 26 Fold:Sec1/munc18-like (SM) proteins Superfamily:Sec1/munc18-like (SM) proteins Family:Sec1/munc18-like (SM) proteins 25 d1o73a_ not modelled 13.7 9 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 26 d1nhoa_ not modelled 12.6 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 27 c3cynC_ not modelled 12.5 5 PDB header:oxidoreductase Chain: C: PDB Molecule:probable glutathione peroxidase 8; PDBTitle: the structure of human gpx8 28 c3me5A_ not modelled 12.4 63 PDB header:transferase Chain: A: PDB Molecule:cytosine-specific methyltransferase; PDBTitle: crystal structure of putative dna cytosine methylase from shigella2 flexneri 2a str. 301 29 d1st6a4 not modelled 12.1 12 Fold:Four-helical up-and-down bundle Superfamily:alpha-catenin/vinculin-like Family:alpha-catenin/vinculin 30 d2gs4a1 not modelled 11.5 14 Fold:Ferritin-like Superfamily:Ferritin-like Family:YciF-like 31 c2l5lA_ not modelled 11.2 14 PDB header:transport protein Chain: A: PDB Molecule:thioredoxin; PDBTitle: solution structure of thioredoxin from bacteroides vulgatus 32 c3ia1A_ not modelled 10.8 14 PDB header:oxidoreductase Chain: A: PDB Molecule:thio-disulfide isomerase/thioredoxin; PDBTitle: crystal structure of thio-disulfide isomerase from thermus2 thermophilus 33 d1vl6a2 not modelled 10.7 26 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Malic enzyme N-domain 34 d1j08a2 not modelled 10.5 25 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 35 d2fy6a1 not modelled 10.2 15 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 36 c3fkfC_ not modelled 10.2 9 PDB header:oxidoreductase Chain: C: PDB Molecule:thiol-disulfide oxidoreductase; PDBTitle: thiol-disulfide oxidoreductase from bacteroides fragilis nctc 9343 37 c2l57A_ not modelled 10.2 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of an uncharacterized thioredoin-like protein from2 clostridium perfringens 38 c3fvwA_ not modelled 10.1 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative nad(p)h-dependent fmn reductase; PDBTitle: crystal structure of the q8dwd8_strmu protein from2 streptococcus mutans. northeast structural genomics3 consortium target smr99. 39 c2vimA_ not modelled 10.1 8 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: x-ray structure of fasciola hepatica thioredoxin 40 c1ylaB_ not modelled 10.0 15 PDB header:ligase Chain: B: PDB Molecule:ubiquitin-conjugating enzyme e2-25 kda; PDBTitle: ubiquitin-conjugating enzyme e2-25 kda (huntington interacting protein2 2) 41 c3go6B_ not modelled 10.0 27 PDB header:transferase Chain: B: PDB Molecule:ribokinase rbsk; PDBTitle: crystal structure of m. tuberculosis ribokinase (rv2436) in2 complex with ribose and amp-pnp 42 d2dcna1 not modelled 9.9 22 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 43 c3dwvB_ not modelled 9.9 9 PDB header:oxidoreductase Chain: B: PDB Molecule:glutathione peroxidase-like protein; PDBTitle: glutathione peroxidase-type tryparedoxin peroxidase,2 oxidized form 44 d1xwaa_ not modelled 9.8 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 45 c2h2yA_ not modelled 9.7 6 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ubiquitin-conjugating enzyme; PDBTitle: crystal structure of ubiquitin conjugating enzyme e2 from2 plasmodium falciparum 46 c3lhxA_ not modelled 9.6 21 PDB header:transferase Chain: A: PDB Molecule:ketodeoxygluconokinase; PDBTitle: crystal structure of a ketodeoxygluconokinase (kdgk) from2 shigella flexneri 47 c3kp8A_ not modelled 9.6 10 PDB header:oxidoreductase Chain: A: PDB Molecule:vkorc1/thioredoxin domain protein; PDBTitle: the thioredoxin-like domain of a vkor homolog from2 synechococcus sp. 48 d1dn1a_ not modelled 9.5 17 Fold:Sec1/munc18-like (SM) proteins Superfamily:Sec1/munc18-like (SM) proteins Family:Sec1/munc18-like (SM) proteins 49 c3lwaA_ not modelled 9.5 15 PDB header:isomerase Chain: A: PDB Molecule:secreted thiol-disulfide isomerase; PDBTitle: the crystal structure of a secreted thiol-disulfide2 isomerase from corynebacterium glutamicum to 1.75a 50 c2dmlA_ not modelled 9.3 9 PDB header:isomerase Chain: A: PDB Molecule:protein disulfide-isomerase a6; PDBTitle: the solution structure of the first thioredoxin domain of2 mouse protein disulfide-isomerase a6 51 d2djja1 not modelled 9.1 5 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 52 c2p31B_ not modelled 9.1 14 PDB header:oxidoreductase Chain: B: PDB Molecule:glutathione peroxidase 7; PDBTitle: crystal structure of human glutathione peroxidase 7 53 c2ywiA_ not modelled 9.0 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical conserved protein; PDBTitle: crystal structure of uncharacterized conserved protein from2 geobacillus kaustophilus 54 c2e0qA_ not modelled 8.9 8 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of k53e thioredoxin from sulfolobus2 tokodaii strain7 55 d1i5ga_ not modelled 8.8 9 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 56 d1t6ex_ not modelled 8.8 19 Fold:Acid proteases Superfamily:Acid proteases Family:Pepsin-like 57 d1y76a1 not modelled 8.8 22 Fold:L27 domain Superfamily:L27 domain Family:L27 domain 58 d2akja4 not modelled 8.7 24 Fold:Nitrite and sulphite reductase 4Fe-4S domain-like Superfamily:Nitrite and sulphite reductase 4Fe-4S domain-like Family:Nitrite and sulphite reductase 4Fe-4S domain-like 59 c3ha9A_ not modelled 8.6 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized thioredoxin-like protein; PDBTitle: the 1.7a crystal structure of a thioredoxin-like protein from2 aeropyrum pernix 60 c1s6xA_ not modelled 8.5 33 PDB header:toxin Chain: A: PDB Molecule:kvap channel; PDBTitle: solution structure of vstx 61 c2wx4C_ not modelled 8.4 17 PDB header:structural protein Chain: C: PDB Molecule:decapping protein 1; PDBTitle: asymmetric trimer of the drosophila melanogaster dcp1 c-2 terminal domain 62 d1beta_ not modelled 8.2 38 Fold:Cystine-knot cytokines Superfamily:Cystine-knot cytokines Family:Neurotrophin 63 c3hypB_ not modelled 8.2 9 PDB header:electron transport Chain: B: PDB Molecule:thioredoxin; PDBTitle: crystal structure of bacteroides fragilis trxp_s105g mutant 64 c3h8qB_ not modelled 8.1 17 PDB header:oxidoreductase Chain: B: PDB Molecule:thioredoxin reductase 3; PDBTitle: crystal structure of glutaredoxin domain of human thioredoxin2 reductase 3 65 d1jb0j_ not modelled 8.0 19 Fold:Single transmembrane helix Superfamily:Subunit IX of photosystem I reaction centre, PsaJ Family:Subunit IX of photosystem I reaction centre, PsaJ 66 c3fxaA_ not modelled 8.0 23 PDB header:sugar binding protein Chain: A: PDB Molecule:sis domain protein; PDBTitle: crystal structure of a putative sugar-phosphate isomerase2 (lmof2365_0531) from listeria monocytogenes str. 4b f2365 at 1.60 a3 resolution 67 c3pp5A_ not modelled 8.0 17 PDB header:structural protein Chain: A: PDB Molecule:brk1; PDBTitle: high-resolution structure of the trimeric scar/wave complex precursor2 brk1 68 d1uj4a1 not modelled 7.9 24 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:D-ribose-5-phosphate isomerase (RpiA), catalytic domain 69 d1qgva_ not modelled 7.9 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:spliceosomal protein U5-15Kd 70 c3s5oA_ not modelled 7.8 14 PDB header:lyase Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase, mitochondrial; PDBTitle: crystal structure of human 4-hydroxy-2-oxoglutarate aldolase bound to2 pyruvate 71 c3r74B_ not modelled 7.8 18 PDB header:lyase, biosynthetic protein Chain: B: PDB Molecule:anthranilate/para-aminobenzoate synthases component i; PDBTitle: crystal structure of 2-amino-2-desoxyisochorismate synthase (adic)2 synthase phze from burkholderia lata 383 72 d1lk5a1 not modelled 7.8 21 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:D-ribose-5-phosphate isomerase (RpiA), catalytic domain 73 c2dj0A_ not modelled 7.8 8 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:thioredoxin-related transmembrane protein 2; PDBTitle: the solution structure of the thioredoxin domain of human2 thioredoxin-related transmembrane protein 2 74 c3hz4A_ not modelled 7.7 18 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from methanosarcina mazei 75 c3ij2B_ not modelled 7.6 38 PDB header:hormone/protein binding Chain: B: PDB Molecule:beta-nerve growth factor; PDBTitle: ligand-receptor structure 76 d1m0sa1 not modelled 7.5 14 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:D-ribose-5-phosphate isomerase (RpiA), catalytic domain 77 d1rpua_ not modelled 7.5 44 Fold:Tombusvirus P19 core protein, VP19 Superfamily:Tombusvirus P19 core protein, VP19 Family:Tombusvirus P19 core protein, VP19 78 c1rpuA_ not modelled 7.5 44 PDB header:rna binding protein/rna Chain: A: PDB Molecule:19 kda protein; PDBTitle: crystal structure of cirv p19 bound to sirna 79 d1o8xa_ not modelled 7.5 9 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 80 d1fp1d1 not modelled 7.4 14 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Plant O-methyltransferase, N-terminal domain 81 c1xbsA_ not modelled 7.4 27 PDB header:transcription, cell cycle Chain: A: PDB Molecule:dim1-like protein; PDBTitle: crystal structure of human dim2: a dim1-like protein 82 c2nwhA_ not modelled 7.4 21 PDB header:signaling protein,transferase Chain: A: PDB Molecule:carbohydrate kinase; PDBTitle: carbohydrate kinase from agrobacterium tumefaciens 83 c1v98A_ not modelled 7.4 14 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure analysis of thioredoxin from thermus thermophilus 84 c2vc6A_ not modelled 7.3 19 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of mosa from s. meliloti with pyruvate bound 85 c2diyA_ not modelled 7.2 8 PDB header:protein binding Chain: A: PDB Molecule:thioredoxin-like protein 2; PDBTitle: the solution structure of the thioredoxin domain of human2 thioredoxin-like protein 2 86 d2elba1 not modelled 7.2 11 Fold:BAR/IMD domain-like Superfamily:BAR/IMD domain-like Family:BAR domain 87 c1lnzA_ not modelled 7.0 17 PDB header:cell cycle Chain: A: PDB Molecule:spo0b-associated gtp-binding protein; PDBTitle: structure of the obg gtp-binding protein 88 c2vocA_ not modelled 7.0 9 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: thioredoxin a active site mutants form mixed disulfide2 dimers that resemble enzyme-substrate reaction3 intermediate 89 d2gyqa1 not modelled 7.0 15 Fold:Ferritin-like Superfamily:Ferritin-like Family:YciF-like 90 c3etnD_ not modelled 6.8 4 PDB header:isomerase Chain: D: PDB Molecule:putative phosphosugar isomerase involved in capsule PDBTitle: crystal structure of putative phosphosugar isomerase involved in2 capsule formation (yp_209877.1) from bacteroides fragilis nctc 93433 at 1.70 a resolution 91 c3dxbE_ not modelled 6.8 14 PDB header:splicing, transcription Chain: E: PDB Molecule:thioredoxin n-terminally fused to puf60(uhm); PDBTitle: structure of the uhm domain of puf60 fused to thioredoxin 92 d1bndb_ not modelled 6.7 38 Fold:Cystine-knot cytokines Superfamily:Cystine-knot cytokines Family:Neurotrophin 93 d2ucza_ not modelled 6.7 19 Fold:UBC-like Superfamily:UBC-like Family:UBC-related 94 d2b5xa1 not modelled 6.6 10 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 95 c2e7pC_ not modelled 6.5 19 PDB header:electron transport Chain: C: PDB Molecule:glutaredoxin; PDBTitle: crystal structure of the holo form of glutaredoxin c1 from populus2 tremula x tremuloides 96 c2j6pF_ not modelled 6.5 20 PDB header:oxidoreductase Chain: F: PDB Molecule:sb(v)-as(v) reductase; PDBTitle: structure of as-sb reductase from leishmania major 97 d1zmaa1 not modelled 6.5 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 98 c1t00A_ not modelled 6.5 9 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: the structure of thioredoxin from s. coelicolor 99 d2ifqa1 not modelled 6.4 18 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0