Phyre 2 Results for P77579

Email	l.a.kelley@imperial.ac.uk
Description	P77579
Date	Thu Jan 5 12:30:44 GMT 2012
Unique Job ID	f5e17a38d761092e

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c3qnqD_

Top template information

PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system

Confidence and coverage

Confidence:

100.0%

Coverage:

91%

379 residues ( 91% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M A I K K R S A T V V P G A S G A A A A V K N P Q A S K T S F W G E L P Q H V M S G I S R M V P T L I M G G V I L A F S

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence Q L I A Y S W L K I P A E I G I M D A L N S G K F S G F D L S L L K F A W L S Q S F G G V L F G F A I P M F A A F V A N

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ? ? ? ?
?
? ?
? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence S I G G K L A F P A G F I G G L M S T Q P T Q L L N F D P S T M Q W A T S S P V P S T F I G A L I I S I V A G Y L V K W

Secondary structure

SS confidence

Disorder
? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence M N Q K I Q L P D F L L A F K T T F L L P I L S A I F V M L A M Y Y V I T P F G G W I N G G I R T V L T A A G E K G A L

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence M Y A M G I A A A T A I D L G G P I N K A A G F V A F S F T T D H V L P V T A R S I A I V I P P I G L G L A T I I D R R

Secondary structure

SS confidence

Disorder
? ? ?
?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence L T G K R L F N A Q L Y P Q G K T A M F L A F M G I S E G A I P F A L E S P I T A I P S Y M V G A I V G S T A A V W L G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ?
? ? ? ?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . .

Sequence A V Q W F P E S A I W A W P L V T N L G V Y M A G I A L G A V I T A L M V V F L R L M M F R K G K L L I D S L

Secondary structure

SS confidence

Disorder ? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 3qnq chain D

Region: 20 - 414
Aligned: 379
Modelled: 379
Confidence: 100.0%
Identity: 14%
PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system

Phyre2

PDB 2voy chain B

Region: 20 - 58
Aligned: 39
Modelled: 39
Confidence: 30.1%
Identity: 15%
PDB header:hydrolase
Chain: B: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium
PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus

Phyre2

PDB 1u7g chain A

Region: 337 - 406
Aligned: 70
Modelled: 70
Confidence: 27.9%
Identity: 16%
Fold: Ammonium transporter
Superfamily: Ammonium transporter
Family: Ammonium transporter

Phyre2

PDB 3dtu chain B domain 2

Region: 378 - 409
Aligned: 32
Modelled: 32
Confidence: 9.4%
Identity: 13%
Fold: Transmembrane helix hairpin
Superfamily: Cytochrome c oxidase subunit II-like, transmembrane region
Family: Cytochrome c oxidase subunit II-like, transmembrane region

Phyre2

PDB 1ffy chain A domain 1

Region: 17 - 51
Aligned: 35
Modelled: 35
Confidence: 9.0%
Identity: 3%
Fold: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases

Phyre2

PDB 1fft chain B domain 2

Region: 379 - 409
Aligned: 31
Modelled: 31
Confidence: 8.1%
Identity: 10%
Fold: Transmembrane helix hairpin
Superfamily: Cytochrome c oxidase subunit II-like, transmembrane region
Family: Cytochrome c oxidase subunit II-like, transmembrane region

Phyre2

PDB 2ket chain A

Region: 32 - 50
Aligned: 19
Modelled: 19
Confidence: 6.3%
Identity: 16%
PDB header:antibiotic
Chain: A: PDB Molecule:cathelicidin-6;
PDBTitle: solution structure of bmap-27

Phyre2

PDB 3ehb chain B domain 2

Region: 378 - 409
Aligned: 32
Modelled: 32
Confidence: 6.2%
Identity: 13%
Fold: Transmembrane helix hairpin
Superfamily: Cytochrome c oxidase subunit II-like, transmembrane region
Family: Cytochrome c oxidase subunit II-like, transmembrane region

Phyre2

PDB 3nd0 chain A

Region: 284 - 409
Aligned: 126
Modelled: 126
Confidence: 6.2%
Identity: 11%
PDB header:transport protein
Chain: A: PDB Molecule:sll0855 protein;
PDBTitle: x-ray crystal structure of a slow cyanobacterial cl-/h+ antiporter

Phyre2

PDB 2ht2 chain B

Region: 164 - 409
Aligned: 237
Modelled: 240
Confidence: 6.2%
Identity: 10%
PDB header:membrane protein
Chain: B: PDB Molecule:h(+)/cl(-) exchange transporter clca;
PDBTitle: structure of the escherichia coli clc chloride channel2 y445h mutant and fab complex

Phyre2

Detailed template information

#	Template	Alignment Coverage	3D Model	Confidence	% i.d.	Template Information

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

If you use the binding site predictions from 3DLigandSite, please also cite:

3DLigandSite: predicting ligand-binding sites using similar structures.

Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]

Imperial College London

Lawrence Kelley, Benjamin Jefferys

Disclaimer

Terms and Conditions

Component software

Template detection: HHpred 1.51

Secondary structure prediction: Psi-pred 2.5

Disorder prediction: Disopred 2.4

Transmembrane prediction: Memsat_SVM

Multi-template modelling and ab initio: Poing 1.0

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	A	I	K	K	R	S	A	T	V	V	P	G	A	S	G	A	A	A	A	V	K	N	P	Q	A	S	K	T	S	F	W	G	E	L	P	Q	H	V	M	S	G	I	S	R	M	V	P	T	L	I	M	G	G	V	I	L	A	F	S
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	Q	L	I	A	Y	S	W	L	K	I	P	A	E	I	G	I	M	D	A	L	N	S	G	K	F	S	G	F	D	L	S	L	L	K	F	A	W	L	S	Q	S	F	G	G	V	L	F	G	F	A	I	P	M	F	A	A	F	V	A	N
Secondary structure
SS confidence
Disorder			?		?	?	?	?	?	?	?	?	?										?			?	?		?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	S	I	G	G	K	L	A	F	P	A	G	F	I	G	G	L	M	S	T	Q	P	T	Q	L	L	N	F	D	P	S	T	M	Q	W	A	T	S	S	P	V	P	S	T	F	I	G	A	L	I	I	S	I	V	A	G	Y	L	V	K	W
Secondary structure
SS confidence
Disorder																						?	?	?	?	?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	M	N	Q	K	I	Q	L	P	D	F	L	L	A	F	K	T	T	F	L	L	P	I	L	S	A	I	F	V	M	L	A	M	Y	Y	V	I	T	P	F	G	G	W	I	N	G	G	I	R	T	V	L	T	A	A	G	E	K	G	A	L
Secondary structure
SS confidence
Disorder										?
Disorder confidence

	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence	M	Y	A	M	G	I	A	A	A	T	A	I	D	L	G	G	P	I	N	K	A	A	G	F	V	A	F	S	F	T	T	D	H	V	L	P	V	T	A	R	S	I	A	I	V	I	P	P	I	G	L	G	L	A	T	I	I	D	R	R
Secondary structure
SS confidence
Disorder																																?	?	?																										?
Disorder confidence

	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence	L	T	G	K	R	L	F	N	A	Q	L	Y	P	Q	G	K	T	A	M	F	L	A	F	M	G	I	S	E	G	A	I	P	F	A	L	E	S	P	I	T	A	I	P	S	Y	M	V	G	A	I	V	G	S	T	A	A	V	W	L	G
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?							?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.
Sequence	A	V	Q	W	F	P	E	S	A	I	W	A	W	P	L	V	T	N	L	G	V	Y	M	A	G	I	A	L	G	A	V	I	T	A	L	M	V	V	F	L	R	L	M	M	F	R	K	G	K	L	L	I	D	S	L
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?		?																																					?	?	?	?	?	?	?	?	?	?	?
Disorder confidence