Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP31827
DateThu Jan 5 11:48:51 GMT 2012
Unique Job IDf3497155bd904f79

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2iahA_
Top template information
PDB header:membrane protein
Chain: A: PDB Molecule:ferripyoverdine receptor;
PDBTitle: crystal structure of the ferripyoverdine receptor of the outer2 membrane of pseudomonas aeruginosa bound to ferripyoverdine.
Confidence and coverage
Confidence:100.0% Coverage: 84%
664 residues ( 84% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
721 residues ( 91%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKRVLIPGVILCGADVAQAVDDKNMYMHFFEEMTVYAPVPVPVNGNTHYTSESIERLPTG
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   .........70.........80.........90.........100.........110.........120
Sequence  NGNISDLLRTNPAVRMDSTQSTSLNQGDIRPEKISIHGASPYQNAYLIDGISATNNLNPA
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   .........130.........140.........150.........160.........170.........180
Sequence  NESDASSATNISGMSQGYYLDVSLLDNVTLYDSFVPVEFGRFNGGVIDAKIKRFNADDSK
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   .........190.........200.........210.........220.........230.........240
Sequence  VKLGYRTTRSDWLTSHIDENNKSAFNQGSSGSTYYSPDFKKNFYTLSFNQELADNFGVTA
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   .........250.........260.........270.........280.........290.........300
Sequence  GLSRRQSDITRADYVSNDGIVAGRAQYKNVIDTALSKFTWFASDRFTHDLTLKYTGSSRD
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   .........310.........320.........330.........340.........350.........360
Sequence  YNTSTFPQSDREMGNKSYGLAWDMDTQLAWAKLRTTVGWDHISDYTRHDHDIWYTELSCT
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   .........370.........380.........390.........400.........410.........420
Sequence  YGDITGRCTRGGLGHISQAVDNYTFKTRLDWQKFAVGNVSHQPYFGAEYIYSDAWTERHN
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   .........430.........440.........450.........460.........470.........480
Sequence  QSESYVINAAGKKTNHTIYHKGKGRLGIDNYTLYMADRISWRNVSLMPGVRYDYDNYLSN
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   .........490.........500.........510.........520.........530.........540
Sequence  HNISPRFMTEWDIFANQTSMITAGYNRYYGGNILDMGLRDIRNSWTESVSGNKTLTRYQD
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   .........550.........560.........570.........580.........590.........600
Sequence  LKTPYNDELAMGLQQKIGKNVIARANYVYREAHDQISKSSRTDSATKTTITEYNNDGKTK
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   .........610.........620.........630.........640.........650.........660
Sequence  THSFSLSFELAEPLHIRQVDINPQIVFSYIKSKGNLSLNNGYEESNTGDNQVVYNGNLVS
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   .........670.........680.........690.........700.........710.........720
Sequence  YDSVPVADFNNPLKISLNMDFTHQPSGLVWANTLAWQEARKARIILGKTNAQYISEYSDY
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   .........730.........740.........750.........760.........770.........780
Sequence  KQYVDEKLDSSLTWDTRLSWTPQFLQQQNLTISADILNVLDSKTAVDTTNTGVATYASGR
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   .........790
Sequence  TFWLDVSMKF
Secondary structure 
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?
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2iah chain A

3D model

Region: 18 - 790
Aligned: 664
Modelled: 697
Confidence: 100.0%
Identity: 13%
PDB header:membrane protein
Chain: A: PDB Molecule:ferripyoverdine receptor;
PDBTitle: crystal structure of the ferripyoverdine receptor of the outer2 membrane of pseudomonas aeruginosa bound to ferripyoverdine.

Phyre2

PDB 1by5 chain A

3D model

Region: 19 - 790
Aligned: 685
Modelled: 699
Confidence: 100.0%
Identity: 11%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 2grx chain B

3D model

Region: 20 - 790
Aligned: 678
Modelled: 678
Confidence: 100.0%
Identity: 12%
PDB header:metal transport
Chain: B: PDB Molecule:ferrichrome-iron receptor;
PDBTitle: crystal structure of tonb in complex with fhua, e. coli2 outer membrane receptor for ferrichrome

Phyre2

PDB 1xkh chain C

3D model

Region: 14 - 790
Aligned: 673
Modelled: 662
Confidence: 100.0%
Identity: 11%
PDB header:membrane protein
Chain: C: PDB Molecule:ferripyoverdine receptor;
PDBTitle: pyoverdine outer membrane receptor fpva from pseudomonas aeruginosa2 pao1 bound to pyoverdine

Phyre2

PDB 3fhh chain A

3D model

Region: 31 - 790
Aligned: 607
Modelled: 626
Confidence: 100.0%
Identity: 18%
PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane heme receptor shua;
PDBTitle: crystal structure of the heme/hemoglobin outer membrane2 transporter shua from shigella dysenteriae

Phyre2

PDB 1xkw chain A

3D model

Region: 24 - 790
Aligned: 644
Modelled: 675
Confidence: 100.0%
Identity: 11%
PDB header:membrane protein
Chain: A: PDB Molecule:fe(iii)-pyochelin receptor;
PDBTitle: pyochelin outer membrane receptor fpta from pseudomonas2 aeruginosa

Phyre2

PDB 3qlb chain A

3D model

Region: 21 - 790
Aligned: 657
Modelled: 676
Confidence: 100.0%
Identity: 11%
PDB header:metal transport
Chain: A: PDB Molecule:enantio-pyochelin receptor;
PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin

Phyre2

PDB 3csl chain B

3D model

Region: 39 - 790
Aligned: 689
Modelled: 708
Confidence: 100.0%
Identity: 13%
PDB header:membrane protein/heme binding protein
Chain: B: PDB Molecule:hasr protein;
PDBTitle: structure of the serratia marcescens hemophore receptor hasr in2 complex with its hemophore hasa and heme

Phyre2

PDB 1fep chain A

3D model

Region: 31 - 790
Aligned: 660
Modelled: 689
Confidence: 100.0%
Identity: 13%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 1kmo chain A

3D model

Region: 32 - 790
Aligned: 646
Modelled: 672
Confidence: 100.0%
Identity: 14%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 1po3 chain A

3D model

Region: 38 - 790
Aligned: 635
Modelled: 658
Confidence: 100.0%
Identity: 13%
PDB header:membrane protein
Chain: A: PDB Molecule:iron(iii) dicitrate transport protein feca
PDBTitle: crystal structure of ferric citrate transporter feca in2 complex with ferric citrate

Phyre2

PDB 2guf chain A domain 1

3D model

Region: 31 - 790
Aligned: 540
Modelled: 602
Confidence: 100.0%
Identity: 18%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 2hdi chain A

3D model

Region: 31 - 790
Aligned: 570
Modelled: 599
Confidence: 100.0%
Identity: 15%
PDB header:protein transport,antimicrobial protein
Chain: A: PDB Molecule:colicin i receptor;
PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia.

Phyre2

PDB 3efm chain A

3D model

Region: 18 - 769
Aligned: 552
Modelled: 573
Confidence: 100.0%
Identity: 14%
PDB header:membrane protein
Chain: A: PDB Molecule:ferric alcaligin siderophore receptor;
PDBTitle: structure of the alcaligin outer membrane recepteur faua from2 bordetella pertussis

Phyre2

PDB 1t16 chain A

3D model

Region: 485 - 790
Aligned: 277
Modelled: 286
Confidence: 99.2%
Identity: 8%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Outer membrane protein transport protein

Phyre2

PDB 3dwo chain X

3D model

Region: 377 - 742
Aligned: 309
Modelled: 324
Confidence: 94.9%
Identity: 9%
PDB header:membrane protein
Chain: X: PDB Molecule:probable outer membrane protein;
PDBTitle: crystal structure of a pseudomonas aeruginosa fadl homologue

Phyre2

PDB 3brz chain A

3D model

Region: 469 - 742
Aligned: 213
Modelled: 223
Confidence: 90.0%
Identity: 10%
PDB header:transport protein
Chain: A: PDB Molecule:todx;
PDBTitle: crystal structure of the pseudomonas putida toluene2 transporter todx

Phyre2

PDB 3k07 chain A

3D model

Region: 4 - 75
Aligned: 63
Modelled: 70
Confidence: 29.9%
Identity: 6%
PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa

Phyre2

PDB 1oy8 chain A

3D model

Region: 4 - 74
Aligned: 62
Modelled: 71
Confidence: 24.8%
Identity: 15%
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump

Phyre2

PDB 2a1j chain A domain 1

3D model

Region: 66 - 75
Aligned: 10
Modelled: 10
Confidence: 20.0%
Identity: 40%
Fold: SAM domain-like
Superfamily: RuvA domain 2-like
Family: Hef domain-like

Phyre2
1

c2iahA_
2

d1by5a_
3

c2grxB_
4

c1xkhC_
5

c3fhhA_
6

c1xkwA_
7

c3qlbA_
8

c3cslB_
9

d1fepa_
10

d1kmoa_
11

c1po3A_
12

d2gufa1
13

c2hdiA_
14

c3efmA_
15

d1t16a_
16

c3dwoX_
17

c3brzA_
18

c3k07A_
19

c1oy8A_
20

d2a1ja1
21



22



23



24






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2iahA_



100.0 13 PDB header:membrane protein
Chain: A: PDB Molecule:ferripyoverdine receptor;
PDBTitle: crystal structure of the ferripyoverdine receptor of the outer2 membrane of pseudomonas aeruginosa bound to ferripyoverdine.
2d1by5a_



100.0 11 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
3c2grxB_



100.0 12 PDB header:metal transport
Chain: B: PDB Molecule:ferrichrome-iron receptor;
PDBTitle: crystal structure of tonb in complex with fhua, e. coli2 outer membrane receptor for ferrichrome
4c1xkhC_



100.0 11 PDB header:membrane protein
Chain: C: PDB Molecule:ferripyoverdine receptor;
PDBTitle: pyoverdine outer membrane receptor fpva from pseudomonas aeruginosa2 pao1 bound to pyoverdine
5c3fhhA_



100.0 18 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane heme receptor shua;
PDBTitle: crystal structure of the heme/hemoglobin outer membrane2 transporter shua from shigella dysenteriae
6c1xkwA_



100.0 11 PDB header:membrane protein
Chain: A: PDB Molecule:fe(iii)-pyochelin receptor;
PDBTitle: pyochelin outer membrane receptor fpta from pseudomonas2 aeruginosa
7c3qlbA_



100.0 11 PDB header:metal transport
Chain: A: PDB Molecule:enantio-pyochelin receptor;
PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin
8c3cslB_



100.0 13 PDB header:membrane protein/heme binding protein
Chain: B: PDB Molecule:hasr protein;
PDBTitle: structure of the serratia marcescens hemophore receptor hasr in2 complex with its hemophore hasa and heme
9d1fepa_



100.0 13 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
10d1kmoa_



100.0 14 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
11c1po3A_



100.0 13 PDB header:membrane protein
Chain: A: PDB Molecule:iron(iii) dicitrate transport protein feca
PDBTitle: crystal structure of ferric citrate transporter feca in2 complex with ferric citrate
12d2gufa1



100.0 18 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
13c2hdiA_



100.0 15 PDB header:protein transport,antimicrobial protein
Chain: A: PDB Molecule:colicin i receptor;
PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia.
14c3efmA_



100.0 14 PDB header:membrane protein
Chain: A: PDB Molecule:ferric alcaligin siderophore receptor;
PDBTitle: structure of the alcaligin outer membrane recepteur faua from2 bordetella pertussis
15d1t16a_



99.2 8 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Outer membrane protein transport protein
16c3dwoX_



94.9 9 PDB header:membrane protein
Chain: X: PDB Molecule:probable outer membrane protein;
PDBTitle: crystal structure of a pseudomonas aeruginosa fadl homologue
17c3brzA_



90.0 10 PDB header:transport protein
Chain: A: PDB Molecule:todx;
PDBTitle: crystal structure of the pseudomonas putida toluene2 transporter todx
18c3k07A_



29.9 6 PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa
19c1oy8A_



24.8 15 PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
20d2a1ja1



20.0 40 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
21d2jnaa1



not modelled 7.8 16 Fold:Dodecin subunit-like
Superfamily:YdgH-like
Family:YdgH-like
22c2e6zA_



not modelled 6.5 21 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor spt5;
PDBTitle: solution structure of the second kow motif of human2 transcription elongation factor spt5
23c1n0wB_



not modelled 6.5 38 PDB header:gene regulation/antitumor protein
Chain: B: PDB Molecule:breast cancer type 2 susceptibility protein;
PDBTitle: crystal structure of a rad51-brca2 brc repeat complex
24d2aq0a1



not modelled 6.0 36 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0