Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP77495
DateThu Jan 5 12:29:54 GMT 2012
Unique Job IDea2a3c3ac7b6bb48

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1pg4a_
Top template information
Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
Confidence and coverage
Confidence:100.0% Coverage: 96%
604 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFARWFCEGRTNLCHNAIDR
Secondary structure 
SS confidence 
Disorder  ??
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  WLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRSLGVQRGDRVLVYMPMIAE
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  AHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIVSADAGARGGKIIPYKKLLDD
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  AISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQHIGARVPVAWLESNETSCILYT
Secondary structure 
SS confidence 
Disorder 
???
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  SGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGSVFFCASDIGWVVGHSYIVYAPLLAG
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  MATIVYEGLPTWPDCGVWWTIVEKYQVSRMFSAPTAIRVLKKFPTAEIRKHDLSSLEVLY
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  LAGEPLDEPTASWVSNTLDVPVIDNYWQTESGWPIMAIARGLDDRPTRLGSPGVPMYGYN
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  VQLLNEVTGEPCGVNEKGMLVVEGPLPPGCIQTIWGDDGRFVKTYWSLFSRPVYATFDWG
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  IRDADGYHFILGRTDDVINVAGHRLGTREIEESISSHPGVAEVAVVGVKDALKGQVAVAF
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  VIPKESDSLEDRDVAHSQEKAIMALVDSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQA
Secondary structure 
SS confidence 
Disorder 
?????????
Disorder confidence 
 
   .........610.........620........
Sequence  ICEGRDPGDLTTIDDPASLDQIRQAMEE
Secondary structure 
SS confidence 
Disorder 
??
??
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1pg4 chain A

3D model

Region: 3 - 624
Aligned: 604
Modelled: 617
Confidence: 100.0%
Identity: 37%
Fold: Acetyl-CoA synthetase-like
Superfamily: Acetyl-CoA synthetase-like
Family: Acetyl-CoA synthetase-like

Phyre2

PDB 1ry2 chain A

3D model

Region: 3 - 627
Aligned: 600
Modelled: 625
Confidence: 100.0%
Identity: 39%
Fold: Acetyl-CoA synthetase-like
Superfamily: Acetyl-CoA synthetase-like
Family: Acetyl-CoA synthetase-like

Phyre2

PDB 2vsq chain A

3D model

Region: 3 - 627
Aligned: 559
Modelled: 584
Confidence: 100.0%
Identity: 20%
PDB header:ligase
Chain: A: PDB Molecule:surfactin synthetase subunit 3;
PDBTitle: structure of surfactin a synthetase c (srfa-c), a2 nonribosomal peptide synthetase termination module

Phyre2

PDB 3etc chain B

3D model

Region: 44 - 587
Aligned: 513
Modelled: 537
Confidence: 100.0%
Identity: 24%
PDB header:ligase
Chain: B: PDB Molecule:amp-binding protein;
PDBTitle: 2.1 a structure of acyl-adenylate synthetase from methanosarcina2 acetivorans containing a link between lys256 and cys298

Phyre2

PDB 3cw9 chain A domain 1

3D model

Region: 52 - 603
Aligned: 500
Modelled: 527
Confidence: 100.0%
Identity: 24%
Fold: Acetyl-CoA synthetase-like
Superfamily: Acetyl-CoA synthetase-like
Family: Acetyl-CoA synthetase-like

Phyre2

PDB 3e7w chain A

3D model

Region: 53 - 602
Aligned: 497
Modelled: 514
Confidence: 100.0%
Identity: 20%
PDB header:ligase
Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1;
PDBTitle: crystal structure of dlta: implications for the reaction2 mechanism of non-ribosomal peptide synthetase (nrps)3 adenylation domains

Phyre2

PDB 3tsy chain A

3D model

Region: 53 - 595
Aligned: 500
Modelled: 524
Confidence: 100.0%
Identity: 17%
PDB header:ligase, transferase
Chain: A: PDB Molecule:fusion protein 4-coumarate--coa ligase 1, resveratrol
PDBTitle: 4-coumaroyl-coa ligase::stilbene synthase fusion protein

Phyre2

PDB 1mdb chain A

3D model

Region: 25 - 603
Aligned: 527
Modelled: 558
Confidence: 100.0%
Identity: 21%
Fold: Acetyl-CoA synthetase-like
Superfamily: Acetyl-CoA synthetase-like
Family: Acetyl-CoA synthetase-like

Phyre2

PDB 3eyn chain B

3D model

Region: 43 - 602
Aligned: 521
Modelled: 551
Confidence: 100.0%
Identity: 25%
PDB header:ligase
Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a;
PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa

Phyre2

PDB 3ni2 chain A

3D model

Region: 53 - 600
Aligned: 504
Modelled: 520
Confidence: 100.0%
Identity: 24%
PDB header:ligase
Chain: A: PDB Molecule:4-coumarate:coa ligase;
PDBTitle: crystal structures and enzymatic mechanisms of a populus tomentosa 4-2 coumarate:coa ligase

Phyre2

PDB 3kxw chain A

3D model

Region: 53 - 612
Aligned: 521
Modelled: 530
Confidence: 100.0%
Identity: 18%
PDB header:ligase
Chain: A: PDB Molecule:saframycin mx1 synthetase b;
PDBTitle: the crystal structure of fatty acid amp ligase from legionella2 pneumophila

Phyre2

PDB 3gqw chain B

3D model

Region: 51 - 603
Aligned: 502
Modelled: 524
Confidence: 100.0%
Identity: 17%
PDB header:ligase
Chain: B: PDB Molecule:fatty acid amp ligase;
PDBTitle: crystal structure of a fatty acid amp ligase from e. coli with an acyl2 adenylate product bound

Phyre2

PDB 3ite chain B

3D model

Region: 55 - 599
Aligned: 486
Modelled: 511
Confidence: 100.0%
Identity: 19%
PDB header:ligase
Chain: B: PDB Molecule:sidn siderophore synthetase;
PDBTitle: the third adenylation domain of the fungal sidn non-2 ribosomal peptide synthetase

Phyre2

PDB 2d1t chain A

3D model

Region: 36 - 605
Aligned: 533
Modelled: 559
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: A: PDB Molecule:luciferin 4-monooxygenase;
PDBTitle: crystal structure of the thermostable japanese firefly2 luciferase red-color emission s286n mutant complexed with3 high-energy intermediate analogue

Phyre2

PDB 2v7b chain B

3D model

Region: 53 - 600
Aligned: 487
Modelled: 532
Confidence: 100.0%
Identity: 20%
PDB header:ligase
Chain: B: PDB Molecule:benzoate-coenzyme a ligase;
PDBTitle: crystal structures of a benzoate coa ligase from2 burkholderia xenovorans lb400

Phyre2

PDB 1amu chain A

3D model

Region: 29 - 600
Aligned: 496
Modelled: 541
Confidence: 100.0%
Identity: 17%
Fold: Acetyl-CoA synthetase-like
Superfamily: Acetyl-CoA synthetase-like
Family: Acetyl-CoA synthetase-like

Phyre2

PDB 1amu chain B

3D model

Region: 31 - 600
Aligned: 493
Modelled: 533
Confidence: 100.0%
Identity: 16%
PDB header:peptide synthetase
Chain: B: PDB Molecule:gramicidin synthetase 1;
PDBTitle: phenylalanine activating domain of gramicidin synthetase 12 in a complex with amp and phenylalanine

Phyre2

PDB 3l8c chain A

3D model

Region: 50 - 603
Aligned: 499
Modelled: 521
Confidence: 100.0%
Identity: 17%
PDB header:ligase
Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1;
PDBTitle: structure of probable d-alanine--poly(phosphoribitol) ligase2 subunit-1 from streptococcus pyogenes

Phyre2

PDB 3dhv chain A

3D model

Region: 54 - 604
Aligned: 497
Modelled: 520
Confidence: 100.0%
Identity: 19%
PDB header:ligase
Chain: A: PDB Molecule:d-alanine-poly(phosphoribitol) ligase;
PDBTitle: crystal structure of dlta protein in complex with d-alanine2 adenylate

Phyre2

PDB 1lci chain A

3D model

Region: 33 - 600
Aligned: 515
Modelled: 564
Confidence: 100.0%
Identity: 17%
Fold: Acetyl-CoA synthetase-like
Superfamily: Acetyl-CoA synthetase-like
Family: Acetyl-CoA synthetase-like

Phyre2
1
d1pg4a_
2
d1ry2a_
3
c2vsqA_
4
c3etcB_
5
d3cw9a1
6
c3e7wA_
7
c3tsyA_
8
d1mdba_
9
c3eynB_
10
c3ni2A_
11
c3kxwA_
12
c3gqwB_
13
c3iteB_
14
c2d1tA_
15
c2v7bB_
16
d1amua_
17
c1amuB_
18
c3l8cA_
19
c3dhvA_
20
d1lcia_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
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53
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1pg4a_
100.0 37 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
2d1ry2a_
100.0 39 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
3c2vsqA_
100.0 20 PDB header:ligase
Chain: A: PDB Molecule:surfactin synthetase subunit 3;
PDBTitle: structure of surfactin a synthetase c (srfa-c), a2 nonribosomal peptide synthetase termination module
4c3etcB_
100.0 24 PDB header:ligase
Chain: B: PDB Molecule:amp-binding protein;
PDBTitle: 2.1 a structure of acyl-adenylate synthetase from methanosarcina2 acetivorans containing a link between lys256 and cys298
5d3cw9a1
100.0 24 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
6c3e7wA_
100.0 20 PDB header:ligase
Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1;
PDBTitle: crystal structure of dlta: implications for the reaction2 mechanism of non-ribosomal peptide synthetase (nrps)3 adenylation domains
7c3tsyA_
100.0 17 PDB header:ligase, transferase
Chain: A: PDB Molecule:fusion protein 4-coumarate--coa ligase 1, resveratrol
PDBTitle: 4-coumaroyl-coa ligase::stilbene synthase fusion protein
8d1mdba_
100.0 21 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
9c3eynB_
100.0 25 PDB header:ligase
Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a;
PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa
10c3ni2A_
100.0 24 PDB header:ligase
Chain: A: PDB Molecule:4-coumarate:coa ligase;
PDBTitle: crystal structures and enzymatic mechanisms of a populus tomentosa 4-2 coumarate:coa ligase
11c3kxwA_
100.0 18 PDB header:ligase
Chain: A: PDB Molecule:saframycin mx1 synthetase b;
PDBTitle: the crystal structure of fatty acid amp ligase from legionella2 pneumophila
12c3gqwB_
100.0 17 PDB header:ligase
Chain: B: PDB Molecule:fatty acid amp ligase;
PDBTitle: crystal structure of a fatty acid amp ligase from e. coli with an acyl2 adenylate product bound
13c3iteB_
100.0 19 PDB header:ligase
Chain: B: PDB Molecule:sidn siderophore synthetase;
PDBTitle: the third adenylation domain of the fungal sidn non-2 ribosomal peptide synthetase
14c2d1tA_
100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:luciferin 4-monooxygenase;
PDBTitle: crystal structure of the thermostable japanese firefly2 luciferase red-color emission s286n mutant complexed with3 high-energy intermediate analogue
15c2v7bB_
100.0 20 PDB header:ligase
Chain: B: PDB Molecule:benzoate-coenzyme a ligase;
PDBTitle: crystal structures of a benzoate coa ligase from2 burkholderia xenovorans lb400
16d1amua_
100.0 17 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
17c1amuB_
100.0 16 PDB header:peptide synthetase
Chain: B: PDB Molecule:gramicidin synthetase 1;
PDBTitle: phenylalanine activating domain of gramicidin synthetase 12 in a complex with amp and phenylalanine
18c3l8cA_
100.0 17 PDB header:ligase
Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1;
PDBTitle: structure of probable d-alanine--poly(phosphoribitol) ligase2 subunit-1 from streptococcus pyogenes
19c3dhvA_
100.0 19 PDB header:ligase
Chain: A: PDB Molecule:d-alanine-poly(phosphoribitol) ligase;
PDBTitle: crystal structure of dlta protein in complex with d-alanine2 adenylate
20d1lcia_
100.0 17 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
21c3g7sA_
not modelled 100.0 21 PDB header:ligase
Chain: A: PDB Molecule:long-chain-fatty-acid--coa ligase (fadd-1);
PDBTitle: crystal structure of a long-chain-fatty-acid-coa ligase2 (fadd1) from archaeoglobus fulgidus
22d1v25a_
not modelled 100.0 16 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
23c3iplB_
not modelled 100.0 18 PDB header:ligase
Chain: B: PDB Molecule:2-succinylbenzoate--coa ligase;
PDBTitle: crystal structure of o-succinylbenzoic acid-coa ligase from2 staphylococcus aureus subsp. aureus mu50
24c3nyrA_
not modelled 100.0 21 PDB header:ligase
Chain: A: PDB Molecule:malonyl-coa ligase;
PDBTitle: malonyl-coa ligase ternary product complex with malonyl-coa and amp2 bound
25c3o82B_
not modelled 100.0 19 PDB header:ligase
Chain: B: PDB Molecule:peptide arylation enzyme;
PDBTitle: structure of base n-terminal domain from acinetobacter baumannii bound2 to 5'-o-[n-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine
26c3o82A_
not modelled 100.0 18 PDB header:ligase
Chain: A: PDB Molecule:peptide arylation enzyme;
PDBTitle: structure of base n-terminal domain from acinetobacter baumannii bound2 to 5'-o-[n-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine
27c3ivrA_
not modelled 100.0 20 PDB header:ligase
Chain: A: PDB Molecule:putative long-chain-fatty-acid coa ligase;
PDBTitle: crystal structure of putative long-chain-fatty-acid coa ligase from2 rhodopseudomonas palustris cga009
28c3e53A_
not modelled 100.0 19 PDB header:ligase
Chain: A: PDB Molecule:fatty-acid-coa ligase fadd28;
PDBTitle: crystal structure of n-terminal domain of a fatty acyl amp2 ligase faal28 from mycobacterium tuberculosis
29c2y4oA_
not modelled 100.0 18 PDB header:ligase
Chain: A: PDB Molecule:phenylacetate-coenzyme a ligase;
PDBTitle: crystal structure of paak2 in complex with phenylacetyl adenylate
30c2y27B_
not modelled 100.0 19 PDB header:ligase
Chain: B: PDB Molecule:phenylacetate-coenzyme a ligase;
PDBTitle: crystal structure of paak1 in complex with atp from2 burkholderia cenocepacia
31c3qovD_
not modelled 100.0 15 PDB header:ligase
Chain: D: PDB Molecule:phenylacetate-coenzyme a ligase;
PDBTitle: crystal structure of a hypothetical acyl-coa ligase (bt_0428) from2 bacteroides thetaiotaomicron vpi-5482 at 2.20 a resolution
32c3hguB_
not modelled 100.0 14 PDB header:biosynthetic protein
Chain: B: PDB Molecule:ehpf;
PDBTitle: structure of phenazine antibiotic biosynthesis protein
33c3laxA_
not modelled 99.6 14 PDB header:ligase
Chain: A: PDB Molecule:phenylacetate-coenzyme a ligase;
PDBTitle: the crystal structure of a domain of phenylacetate-coenzyme2 a ligase from bacteroides vulgatus atcc 8482
34d2ayia1
not modelled 74.2 27 Fold:Thermophilic metalloprotease-like
Superfamily:Thermophilic metalloprotease-like
Family:Thermophilic metalloprotease (M29)
35c3smaD_
not modelled 63.8 25 PDB header:transferase
Chain: D: PDB Molecule:frbf;
PDBTitle: a new n-acetyltransferase fold in the structure and mechanism of the2 phosphonate biosynthetic enzyme frbf
36d2nyga1
not modelled 58.9 30 Fold:TTHA0583/YokD-like
Superfamily:TTHA0583/YokD-like
Family:Aminoglycoside 3-N-acetyltransferase-like
37c3e4fB_
not modelled 53.4 23 PDB header:transferase
Chain: B: PDB Molecule:aminoglycoside n3-acetyltransferase;
PDBTitle: crystal structure of ba2930- a putative aminoglycoside n3-2 acetyltransferase from bacillus anthracis
38d1pl8a2
not modelled 52.4 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
39d1piwa2
not modelled 48.8 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
40d1e3ja2
not modelled 47.6 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
41c3ippA_
not modelled 44.0 17 PDB header:transferase
Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase ynje;
PDBTitle: crystal structure of sulfur-free ynje
42c1uarA_
not modelled 43.2 17 PDB header:transferase
Chain: A: PDB Molecule:rhodanese;
PDBTitle: crystal structure of rhodanese from thermus thermophilus hb8
43d1z7wa1
not modelled 40.0 12 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
44d1zjca1
not modelled 38.4 20 Fold:Thermophilic metalloprotease-like
Superfamily:Thermophilic metalloprotease-like
Family:Thermophilic metalloprotease (M29)
45c2ywiA_
not modelled 34.9 22 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical conserved protein;
PDBTitle: crystal structure of uncharacterized conserved protein from2 geobacillus kaustophilus
46c3olhA_
not modelled 33.9 10 PDB header:transferase
Chain: A: PDB Molecule:3-mercaptopyruvate sulfurtransferase;
PDBTitle: human 3-mercaptopyruvate sulfurtransferase
47d1kola2
not modelled 33.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
48c3pdiG_
not modelled 28.6 14 PDB header:protein binding
Chain: G: PDB Molecule:nitrogenase mofe cofactor biosynthesis protein nife;
PDBTitle: precursor bound nifen
49d1udxa3
not modelled 28.1 24 Fold:Obg GTP-binding protein C-terminal domain
Superfamily:Obg GTP-binding protein C-terminal domain
Family:Obg GTP-binding protein C-terminal domain
50d1d1ta2
not modelled 27.9 7 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
51c3pc3A_
not modelled 26.9 13 PDB header:lyase
Chain: A: PDB Molecule:cg1753, isoform a;
PDBTitle: full length structure of cystathionine beta-synthase from drosophila2 in complex with aminoacrylate
52c3aaxB_
not modelled 25.3 13 PDB header:transferase
Chain: B: PDB Molecule:putative thiosulfate sulfurtransferase;
PDBTitle: crystal structure of probable thiosulfate sulfurtransferase2 cysa3 (rv3117) from mycobacterium tuberculosis: monoclinic3 form
53c3bcxA_
not modelled 25.0 23 PDB header:transferase
Chain: A: PDB Molecule:cdp-6-deoxy-l-threo-d-glycero-4-hexulose-3-
PDBTitle: e1 dehydrase
54d1ykfa2
not modelled 24.6 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
55d1vkma_
not modelled 24.5 12 Fold:Indigoidine synthase A-like
Superfamily:Indigoidine synthase A-like
Family:Indigoidine synthase A-like
56d1uufa2
not modelled 24.5 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
57d1nula_
not modelled 24.3 15 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
58d1e3ia2
not modelled 23.8 7 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
59c2k85A_
not modelled 23.8 8 PDB header:protein binding
Chain: A: PDB Molecule:glucocorticoid receptor dna-binding factor 1;
PDBTitle: p190-a rhogap ff1 domain
60c3nnkC_
not modelled 22.6 16 PDB header:transferase
Chain: C: PDB Molecule:ureidoglycine-glyoxylate aminotransferase;
PDBTitle: biochemical and structural characterization of a ureidoglycine2 aminotransferase in the klebsiella pneumoniae uric acid catabolic3 pathway
61d1qz9a_
not modelled 22.2 8 Fold:PLP-dependent transferase-like
Superfamily:PLP-dependent transferases
Family:Cystathionine synthase-like
62d1f20a1
not modelled 22.2 19 Fold:Reductase/isomerase/elongation factor common domain
Superfamily:Riboflavin synthase domain-like
Family:NADPH-cytochrome p450 reductase FAD-binding domain-like
63d1v74a_
not modelled 21.9 28 Fold:Colicin D/E5 nuclease domain
Superfamily:Colicin D/E5 nuclease domain
Family:Colicin D nuclease domain
64d1ja1a1
not modelled 21.7 17 Fold:Reductase/isomerase/elongation factor common domain
Superfamily:Riboflavin synthase domain-like
Family:NADPH-cytochrome p450 reductase FAD-binding domain-like
65d1iz0a2
not modelled 21.3 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
66d1jqba2
not modelled 20.6 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
67d1okga1
not modelled 19.8 20 Fold:Rhodanese/Cell cycle control phosphatase
Superfamily:Rhodanese/Cell cycle control phosphatase
Family:Multidomain sulfurtransferase (rhodanese)
68c1okgA_
not modelled 19.6 20 PDB header:transferase
Chain: A: PDB Molecule:possible 3-mercaptopyruvate sulfurtransferase;
PDBTitle: 3-mercaptopyruvate sulfurtransferase from leishmania major
69d1p0fa2
not modelled 19.3 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
70d1uara2
not modelled 19.2 17 Fold:Rhodanese/Cell cycle control phosphatase
Superfamily:Rhodanese/Cell cycle control phosphatase
Family:Multidomain sulfurtransferase (rhodanese)
71d1jvba2
not modelled 19.2 8 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
72d1k92a1
not modelled 17.5 15 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
73d1ddga1
not modelled 17.2 19 Fold:Reductase/isomerase/elongation factor common domain
Superfamily:Riboflavin synthase domain-like
Family:NADPH-cytochrome p450 reductase FAD-binding domain-like
74c2vrgA_
not modelled 16.2 5 PDB header:transport
Chain: A: PDB Molecule:multiple coagulation factor deficiency protein 2;
PDBTitle: structure of human mcfd2
75c2l66B_
not modelled 16.1 23 PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulator, abrb family;
PDBTitle: the dna-recognition fold of sso7c4 suggests a new member of spovt-abrb2 superfamily from archaea.
76d1w36b2
not modelled 15.7 16 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
77d1uaaa2
not modelled 15.7 6 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
78d1h2ba2
not modelled 15.3 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
79d1aisa1
not modelled 15.0 24 Fold:TBP-like
Superfamily:TATA-box binding protein-like
Family:TATA-box binding protein (TBP), C-terminal domain
80c2jkzB_
not modelled 14.9 6 PDB header:transferase
Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase;
PDBTitle: saccharomyces cerevisiae hypoxanthine-guanine2 phosphoribosyltransferase in complex with gmp (guanosine 5'3 -monophosphate) (orthorhombic crystal form)
81c2zy3A_
not modelled 14.2 15 PDB header:lyase
Chain: A: PDB Molecule:l-aspartate beta-decarboxylase;
PDBTitle: dodecameric l-aspartate beta-decarboxylase
82d1y7la1
not modelled 14.1 11 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
83d2fzwa2
not modelled 14.0 7 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
84d1a9xa4
not modelled 14.0 14 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:BC N-terminal domain-like
85d1wkva1
not modelled 14.0 13 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
86d1fcja_
not modelled 13.7 11 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
87d2ch1a1
not modelled 13.2 12 Fold:PLP-dependent transferase-like
Superfamily:PLP-dependent transferases
Family:Cystathionine synthase-like
88d1a3xa3
not modelled 13.2 13 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:Pyruvate kinase, C-terminal domain
89d1liua3
not modelled 13.2 20 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:Pyruvate kinase, C-terminal domain
90d2jhfa2
not modelled 13.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
91d2c5sa1
not modelled 12.9 15 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:ThiI-like
92d1u3wa2
not modelled 12.7 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
93c2wh7A_
not modelled 12.7 73 PDB header:hydrolase
Chain: A: PDB Molecule:hyaluronidase-phage associated;
PDBTitle: the partial structure of a group a streptpcoccal phage-2 encoded tail fibre hyaluronate lyase hylp2
94d1i1ga2
not modelled 12.2 22 Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Lrp/AsnC-like transcriptional regulator C-terminal domain
95c1pzmB_
not modelled 12.1 10 PDB header:transferase
Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase;
PDBTitle: crystal structure of hgprt-ase from leishmania tarentolae in complex2 with gmp
96c1b74A_
not modelled 12.1 11 PDB header:isomerase
Chain: A: PDB Molecule:glutamate racemase;
PDBTitle: glutamate racemase from aquifex pyrophilus
97d1cdoa2
not modelled 12.0 8 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
98c2diuA_
not modelled 12.0 19 PDB header:rna binding protein
Chain: A: PDB Molecule:kiaa0430 protein;
PDBTitle: solution structure of the rrm domain of kiaa0430 protein
99c1oftC_
not modelled 11.9 29 PDB header:bacterial cell division inhibitor
Chain: C: PDB Molecule:hypothetical protein pa3008;
PDBTitle: crystal structure of sula from pseudomonas aeruginosa

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0