|   |
1 | . | . | . | . | . | . | . | . | 10 | |
|
. | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | |
. | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | R | I | L | H | T | S | D | W | H | . |
. |
L | G | Q | N | F | Y | S | K | S | R | E | A | E | H | Q | A | F | L | D | W | L | L | E | T | A | Q | T | H | Q | V | D | A | I | I | V | . |
A | G | D | V | F | D | T | G | S | P | P | S | Y | A | R | T | L | Y | N | R | F | V | V | N | L | Q | Q | T | G | C | H | L |
Query Conservation |   |
|
|
|
|
|   |
|
|
|
| . | . |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|
|   |
|
|
| . |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |
|
| . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |
|   |
Template Sequence |   |
I | T | V | L | H | T | N | D | H | H | G | H | F | W | R | N | E | Y | G | E | Y | G | L | A | A | Q | K | T | L | V | D | G | I | R | K | E | V | A | A | E | G | G | S | V | L | L | L | S | G | G | D | I | N | T | G | V | . |
. |
P | E | S | D | L | Q | D | A | E | P | D | F | R | G | M | N | L | V | G | Y | D | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |
|
|
| T | T |
|
| S |
|
| T | T | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
| S |
|
| S | S | S |
| . | . |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |  | T |
|
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . | . |
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
34 | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | |
|
90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | V | L | A | G | N | H | D | S | V | A | T | L | N | E | S | R | D | I | M | A | F | L | N | T | T | V | V | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | A | G | H | A | P | Q | I | L | P | R | R | D | G | T | P | G | A | V | L | C | P | I | P | F | L | R | P | R | D | I | I | T | S | Q | A | G | L | N | G | I |
Query Conservation |   |
  |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . |   |   |
|
|
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
M | . |
A | I | G | N | H | E | F | D | N | P | L | T | V | L | R | Q | Q | E | K | W | A | K | F | P | L | L | S | A | N | I | Y | Q | K | S | T | G | E | R | L | F | K | P | W | A | L | F | K | R | Q | D | L | K | I | A | V | I | G | L | T | T | D | D | T | A | K | I | G | N | P | E | Y | F | T | D | I | E | F | R |
Template Known Secondary structure |   |
 | . |  |
|
| G | G | G | G | S | S |
|  |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |
| S | S |  |  |  | T | T | T |
|
| B | S | S |
|
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |
| T | T |  |  |  |  | S |
| G | G | G | G | T | T |  |  |  |
|
Template Predicted Secondary structure |   |
 | . |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
112 | |
. | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 |
  |
  |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | K | Q | Q | H | L | L | A | A | I | T | D | Y | Y | Q | Q | H | Y | A | D | A | C | K | L | R | G | D | Q | P | L | P | I | I | A | T | G | H | L | T | T | V | G | A | S | K | S | D | A | V | R | D | I | Y | I | G | T | L | D | A | F | P | A | Q | N | F | P | P | A | D | Y | I | A | L | G | H | I | H | R | A | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |
|
|   |
|
|   |
|
|   |
|   |   |   |
Template Sequence |   |
K | P | A | D | E | A | K | L | V | I | Q | E | L | Q | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | E | K | P | D | I | I | I | A | A | T | H | M | G | H | Y | D | N | G | E | H | G | C | N | A | P | G | D | V | E | M | A | R | A | L | P | A | G | . |
. |
. |
S | L | A | M | I | V | G | G | H | S | Q | D | P | V |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | T | T |
|
| S |  |  |  |  |  |  |  | S |
|
|
| G | G | G |
|
| T | T | S |
|
|
|  |  |  |  |  |  |  | S |
| T | T | . | . | . | S | S | S |  |  |  |
|
| S | S |
|
| B |
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|  |  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
191 | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
|
|
. | . | . | . | . | . | 250 | . | . | . | . | . | . | . |
  |
  |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | I | G | G | M | E | H | V | R | Y | C | G | S | P | I | P | L | S | F | D | E | C | G | K | S | K | Y | V | H | L | V | T | F | S | N | G | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |
|   |
|   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
Template Sequence |   |
C | M | A | A | E | . |
. |
N | K | K | Q | V | D | Y | V | P | G | T | P | C | K | P | D | Q | Q | N | G | I | W | I | V | Q | A | H | E | W | G |
Template Known Secondary structure |   |
|  |  |  | T | . | . | T |  |  |
| S | S |
|
| T | T | S |
|
|
|
|  |  |  | T | T |  |  |  |  |
| B |
| S | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
258 | . | 260 | . | . | |
|
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . |
  |