Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	A	L	G	M	I	E	T	R	G	L	V	A	L	I	E	A	S	D	A	M	V	K	A	A	R	V	K	L	V	G	V	K	Q	I	G	G	G	L	C	T	A	M	V	R	G	D	V	A	A	C	K	A	A	T	D	A	G	A
Secondary structure
SS confidence
Disorder		?	?	?							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.
Sequence		A	A	A	Q	R	I	G	E	L	V	S	V	H	V	I	P	R	P	H	G	D	L	E	E	V	F	P	I	G	L	K	G	D	S	S	N	L
Secondary structure
SS confidence
Disorder																											?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3i6p chain F Region: 1 - 90 Aligned: 90 Modelled: 90 Confidence: 100.0% Identity: 100% PDB header:structural protein Chain: F: PDB Molecule:ethanolamine utilization protein eutm; PDBTitle: ethanolamine utilization microcompartment shell subunit, eutm Phyre2 PDB 3ngk chain A Region: 2 - 90 Aligned: 89 Modelled: 89 Confidence: 100.0% Identity: 66% PDB header:unknown function Chain: A: PDB Molecule:propanediol utilization protein pdua; PDBTitle: pdua from salmonella enterica typhimurium Phyre2 PDB 2a10 chain A domain 1 Region: 2 - 95 Aligned: 94 Modelled: 94 Confidence: 100.0% Identity: 38% Fold: Ferredoxin-like Superfamily: CcmK-like Family: CcmK-like Phyre2 PDB 2ewh chain A domain 1 Region: 2 - 91 Aligned: 90 Modelled: 90 Confidence: 100.0% Identity: 53% Fold: Ferredoxin-like Superfamily: CcmK-like Family: CcmK-like Phyre2 PDB 2a1b chain A domain 1 Region: 3 - 95 Aligned: 93 Modelled: 93 Confidence: 100.0% Identity: 54% Fold: Ferredoxin-like Superfamily: CcmK-like Family: CcmK-like Phyre2 PDB 3n79 chain A Region: 1 - 89 Aligned: 89 Modelled: 89 Confidence: 100.0% Identity: 38% PDB header:electron transport Chain: A: PDB Molecule:pdut; PDBTitle: pdut c38s mutant from salmonella enterica typhimurium Phyre2 PDB 3nwg chain A Region: 2 - 94 Aligned: 91 Modelled: 93 Confidence: 100.0% Identity: 27% PDB header:structural protein Chain: A: PDB Molecule:microcompartments protein; PDBTitle: the crystal structure of a microcomparments protein from2 desulfitobacterium hafniense dcb Phyre2 PDB 3io0 chain A Region: 1 - 79 Aligned: 79 Modelled: 79 Confidence: 99.8% Identity: 20% PDB header:structural protein Chain: A: PDB Molecule:etub protein; PDBTitle: crystal structure of etub from clostridium kluyveri Phyre2 PDB 3i82 chain A Region: 2 - 90 Aligned: 89 Modelled: 89 Confidence: 99.6% Identity: 24% PDB header:structural protein Chain: A: PDB Molecule:ethanolamine utilization protein eutl; PDBTitle: ethanolamine utilization microcompartment shell subunit, eutl closed2 form Phyre2 PDB 3cgi chain D Region: 2 - 66 Aligned: 62 Modelled: 65 Confidence: 99.0% Identity: 24% PDB header:unknown function Chain: D: PDB Molecule:propanediol utilization protein pduu; PDBTitle: crystal structure of the pduu shell protein from the pdu2 microcompartment Phyre2 PDB 3ia0 chain C Region: 3 - 66 Aligned: 61 Modelled: 64 Confidence: 99.0% Identity: 25% PDB header:structural protein Chain: C: PDB Molecule:ethanolamine utilization protein euts; PDBTitle: ethanolamine utilization microcompartment shell subunit,2 euts-g39v mutant Phyre2 PDB 3f56 chain F Region: 2 - 69 Aligned: 66 Modelled: 65 Confidence: 97.1% Identity: 21% PDB header:structural protein Chain: F: PDB Molecule:csos1d; PDBTitle: the structure of a previously undetected carboxysome shell2 protein: csos1d from prochlorococcus marinus med4 Phyre2 PDB 2c42 chain A domain 3 Region: 29 - 91 Aligned: 63 Modelled: 63 Confidence: 46.6% Identity: 16% Fold: TK C-terminal domain-like Superfamily: TK C-terminal domain-like Family: Pyruvate-ferredoxin oxidoreductase, PFOR, domain II Phyre2 PDB 1m5s chain A domain 2 Region: 41 - 73 Aligned: 33 Modelled: 33 Confidence: 15.7% Identity: 27% Fold: Ferredoxin-like Superfamily: Formylmethanofuran:tetrahydromethanopterin formyltransferase Family: Formylmethanofuran:tetrahydromethanopterin formyltransferase Phyre2 PDB 2c3y chain A Region: 27 - 91 Aligned: 65 Modelled: 65 Confidence: 14.5% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate-ferredoxin oxidoreductase; PDBTitle: crystal structure of the radical form of2 pyruvate:ferredoxin oxidoreductase from desulfovibrio3 africanus Phyre2 PDB 1ftr chain A domain 2 Region: 41 - 73 Aligned: 33 Modelled: 33 Confidence: 12.5% Identity: 24% Fold: Ferredoxin-like Superfamily: Formylmethanofuran:tetrahydromethanopterin formyltransferase Family: Formylmethanofuran:tetrahydromethanopterin formyltransferase Phyre2 PDB 2qrr chain A domain 1 Region: 27 - 74 Aligned: 47 Modelled: 48 Confidence: 10.7% Identity: 19% Fold: Ferredoxin-like Superfamily: ACT-like Family: NIL domain-like Phyre2 PDB 1m5h chain A domain 2 Region: 41 - 73 Aligned: 33 Modelled: 33 Confidence: 10.3% Identity: 30% Fold: Ferredoxin-like Superfamily: Formylmethanofuran:tetrahydromethanopterin formyltransferase Family: Formylmethanofuran:tetrahydromethanopterin formyltransferase Phyre2 PDB 2ctm chain A domain 1 Region: 19 - 66 Aligned: 48 Modelled: 48 Confidence: 10.2% Identity: 10% Fold: Eukaryotic type KH-domain (KH-domain type I) Superfamily: Eukaryotic type KH-domain (KH-domain type I) Family: Eukaryotic type KH-domain (KH-domain type I) Phyre2 PDB 3dhx chain A domain 1 Region: 27 - 74 Aligned: 47 Modelled: 48 Confidence: 9.1% Identity: 15% Fold: Ferredoxin-like Superfamily: ACT-like Family: NIL domain-like Phyre2 1 c3i6pF_ 2 c3ngkA_ 3 d2a10a1 4 d2ewha1 5 d2a1ba1 6 c3n79A_ 7 c3nwgA_ 8 c3io0A_ 9 c3i82A_ 10 c3cgiD_ 11 c3ia0c_ 12 c3f56F_ 13 d2c42a3 14 d1m5sa2 15 c2c3yA_ 16 d1ftra2 17 d2qrra1 18 d1m5ha2 19 d2ctma1 20 d3dhxa1 21 22 23 24 25 26 27 28 29 30

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3i6pF_ 100.0 100 PDB header:structural protein Chain: F: PDB Molecule:ethanolamine utilization protein eutm; PDBTitle: ethanolamine utilization microcompartment shell subunit, eutm 2 c3ngkA_ 100.0 66 PDB header:unknown function Chain: A: PDB Molecule:propanediol utilization protein pdua; PDBTitle: pdua from salmonella enterica typhimurium 3 d2a10a1 100.0 38 Fold:Ferredoxin-like Superfamily:CcmK-like Family:CcmK-like 4 d2ewha1 100.0 53 Fold:Ferredoxin-like Superfamily:CcmK-like Family:CcmK-like 5 d2a1ba1 100.0 54 Fold:Ferredoxin-like Superfamily:CcmK-like Family:CcmK-like 6 c3n79A_ 100.0 38 PDB header:electron transport Chain: A: PDB Molecule:pdut; PDBTitle: pdut c38s mutant from salmonella enterica typhimurium 7 c3nwgA_ 100.0 27 PDB header:structural protein Chain: A: PDB Molecule:microcompartments protein; PDBTitle: the crystal structure of a microcomparments protein from2 desulfitobacterium hafniense dcb 8 c3io0A_ 99.8 20 PDB header:structural protein Chain: A: PDB Molecule:etub protein; PDBTitle: crystal structure of etub from clostridium kluyveri 9 c3i82A_ 99.6 24 PDB header:structural protein Chain: A: PDB Molecule:ethanolamine utilization protein eutl; PDBTitle: ethanolamine utilization microcompartment shell subunit, eutl closed2 form 10 c3cgiD_ 99.0 24 PDB header:unknown function Chain: D: PDB Molecule:propanediol utilization protein pduu; PDBTitle: crystal structure of the pduu shell protein from the pdu2 microcompartment 11 c3ia0c_ 99.0 25 PDB header:structural protein Chain: C: PDB Molecule:ethanolamine utilization protein euts; PDBTitle: ethanolamine utilization microcompartment shell subunit,2 euts-g39v mutant 12 c3f56F_ 97.1 21 PDB header:structural protein Chain: F: PDB Molecule:csos1d; PDBTitle: the structure of a previously undetected carboxysome shell2 protein: csos1d from prochlorococcus marinus med4 13 d2c42a3 46.6 16 Fold:TK C-terminal domain-like Superfamily:TK C-terminal domain-like Family:Pyruvate-ferredoxin oxidoreductase, PFOR, domain II 14 d1m5sa2 15.7 27 Fold:Ferredoxin-like Superfamily:Formylmethanofuran:tetrahydromethanopterin formyltransferase Family:Formylmethanofuran:tetrahydromethanopterin formyltransferase 15 c2c3yA_ 14.5 15 PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate-ferredoxin oxidoreductase; PDBTitle: crystal structure of the radical form of2 pyruvate:ferredoxin oxidoreductase from desulfovibrio3 africanus 16 d1ftra2 12.5 24 Fold:Ferredoxin-like Superfamily:Formylmethanofuran:tetrahydromethanopterin formyltransferase Family:Formylmethanofuran:tetrahydromethanopterin formyltransferase 17 d2qrra1 10.7 19 Fold:Ferredoxin-like Superfamily:ACT-like Family:NIL domain-like 18 d1m5ha2 10.3 30 Fold:Ferredoxin-like Superfamily:Formylmethanofuran:tetrahydromethanopterin formyltransferase Family:Formylmethanofuran:tetrahydromethanopterin formyltransferase 19 d2ctma1 10.2 10 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 20 d3dhxa1 9.1 15 Fold:Ferredoxin-like Superfamily:ACT-like Family:NIL domain-like 21 c1m5sC_ not modelled 7.7 27 PDB header:transferase Chain: C: PDB Molecule:formylmethanofuran--tetrahydromethanopterin PDBTitle: formylmethanofuran:tetrahydromethanopterin2 fromyltransferase from methanosarcina barkeri 22 c2fhjD_ not modelled 6.7 24 PDB header:transferase Chain: D: PDB Molecule:formylmethanofuran--tetrahydromethanopterin PDBTitle: crystal structure of formylmethanofuran:2 tetrahydromethanopterin formyltransferase in complex with3 its coenzymes 23 d2qn6b1 not modelled 6.6 16 Fold:Ferredoxin-like Superfamily:eIF-2-alpha, C-terminal domain Family:eIF-2-alpha, C-terminal domain 24 d1qd1a1 not modelled 6.3 16 Fold:Ferredoxin-like Superfamily:Formiminotransferase domain of formiminotransferase-cyclodeaminase. Family:Formiminotransferase domain of formiminotransferase-cyclodeaminase. 25 c1qd1A_ not modelled 6.1 16 PDB header:transferase Chain: A: PDB Molecule:formiminotransferase-cyclodeaminase; PDBTitle: the crystal structure of the formiminotransferase domain of2 formiminotransferase-cyclodeaminase. 26 d1j9ba_ not modelled 6.0 17 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:ArsC-like 27 d1xhja_ not modelled 6.0 26 Fold:Alpha-lytic protease prodomain-like Superfamily:Fe-S cluster assembly (FSCA) domain-like Family:NifU C-terminal domain-like 28 d1t23a_ not modelled 5.9 50 Fold:Chromosomal protein MC1 Superfamily:Chromosomal protein MC1 Family:Chromosomal protein MC1 29 c2c1lA_ not modelled 5.6 30 PDB header:hydrolase Chain: A: PDB Molecule:restriction endonuclease; PDBTitle: structure of the bfii restriction endonuclease 30 c1m5hF_ not modelled 5.4 30 PDB header:transferase Chain: F: PDB Molecule:formylmethanofuran--tetrahydromethanopterin PDBTitle: formylmethanofuran:tetrahydromethanopterin2 formyltransferase from archaeoglobus fulgidus

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0