Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	I	S	R	E	T	L	H	Q	L	I	E	N	K	L	C	Q	A	G	L	K	R	E	H	A	A	T	V	A	E	V	L	V	Y	A	D	A	R	G	I	H	S	H	G	A	V	R	V	E	Y	Y	A	E	R	I	S	K	G	G
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	N	R	E	P	E	F	R	L	E	E	T	G	P	C	S	A	I	L	H	A	D	N	A	A	G	Q	V	A	A	K	M	G	M	E	H	A	I	K	T	A	Q	Q	N	G	V	A	V	V	G	I	S	R	M	G	H	S	G	A	I
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	Y	F	V	Q	Q	A	A	R	A	G	F	I	G	I	S	M	C	Q	S	D	P	M	V	V	P	F	G	G	A	E	I	Y	Y	G	T	N	P	L	A	F	A	A	P	G	E	G	D	E	I	L	T	F	D	M	A	T	T	V	Q
Secondary structure
SS confidence
Disorder																																																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	W	G	K	V	L	D	A	R	S	R	N	M	S	I	P	D	T	W	A	V	D	K	N	G	V	P	T	T	D	P	F	A	V	H	A	L	L	P	A	A	G	P	K	G	Y	G	L	M	M	M	I	D	V	L	S	G	V	L	L
Secondary structure
SS confidence
Disorder		?										?																																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	L	P	F	G	R	Q	V	S	S	M	Y	D	D	L	H	A	G	R	N	L	G	Q	L	H	I	V	I	N	P	N	F	F	S	S	S	E	L	F	R	Q	H	L	S	Q	T	M	R	E	L	N	A	I	T	P	A	P	G	F	N
Secondary structure
SS confidence
Disorder			?	?	?		?		?	?	?	?	?	?	?	?	?																			?																							?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.
Sequence		Q	V	Y	Y	P	G	Q	D	Q	D	I	K	Q	R	K	A	A	V	E	G	I	E	I	V	D	D	I	Y	Q	Y	L	I	S	D	A	L	Y	N	T	S	Y	E	T	K	N	P	F	A	Q
Secondary structure
SS confidence
Disorder																				?	?		?																?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1xrh chain A Region: 2 - 342 Aligned: 341 Modelled: 341 Confidence: 100.0% Identity: 96% Fold: L-sulfolactate dehydrogenase-like Superfamily: L-sulfolactate dehydrogenase-like Family: L-sulfolactate dehydrogenase-like Phyre2 PDB 1vbi chain A Region: 1 - 347 Aligned: 340 Modelled: 347 Confidence: 100.0% Identity: 36% PDB header:oxidoreductase Chain: A: PDB Molecule:type 2 malate/lactate dehydrogenase; PDBTitle: crystal structure of type 2 malate/lactate dehydrogenase from thermus2 thermophilus hb8 Phyre2 PDB 1z2i chain A Region: 1 - 345 Aligned: 344 Modelled: 345 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of agrobacterium tumefaciens malate2 dehydrogenase, new york structural genomics consortium Phyre2 PDB 3i0p chain A Region: 1 - 347 Aligned: 343 Modelled: 347 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of malate dehydrogenase from entamoeba histolytica Phyre2 PDB 2g8y chain B Region: 2 - 349 Aligned: 344 Modelled: 344 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: B: PDB Molecule:malate/l-lactate dehydrogenases; PDBTitle: the structure of a putative malate/lactate dehydrogenase from e. coli. Phyre2 PDB 1rfm chain A Region: 3 - 339 Aligned: 332 Modelled: 337 Confidence: 100.0% Identity: 34% Fold: L-sulfolactate dehydrogenase-like Superfamily: L-sulfolactate dehydrogenase-like Family: L-sulfolactate dehydrogenase-like Phyre2 PDB 1wtj chain B Region: 1 - 335 Aligned: 328 Modelled: 335 Confidence: 100.0% Identity: 30% PDB header:oxidoreductase Chain: B: PDB Molecule:ureidoglycolate dehydrogenase; PDBTitle: crystal structure of delta1-piperideine-2-carboxylate2 reductase from pseudomonas syringae pvar.tomato Phyre2 PDB 1nxu chain A Region: 1 - 334 Aligned: 329 Modelled: 329 Confidence: 100.0% Identity: 22% Fold: L-sulfolactate dehydrogenase-like Superfamily: L-sulfolactate dehydrogenase-like Family: L-sulfolactate dehydrogenase-like Phyre2 PDB 3uoe chain B Region: 2 - 335 Aligned: 313 Modelled: 317 Confidence: 100.0% Identity: 30% PDB header:oxidoreductase Chain: B: PDB Molecule:dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from sinorhizobium meliloti Phyre2 PDB 1v9n chain A Region: 1 - 343 Aligned: 327 Modelled: 343 Confidence: 100.0% Identity: 34% PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: structure of malate dehydrogenase from pyrococcus horikoshii ot3 Phyre2 PDB 2ebf chain X domain 2 Region: 33 - 130 Aligned: 67 Modelled: 69 Confidence: 54.3% Identity: 18% Fold: EreA/ChaN-like Superfamily: EreA/ChaN-like Family: PMT domain-like Phyre2 PDB 3b8i chain F Region: 10 - 118 Aligned: 93 Modelled: 106 Confidence: 50.4% Identity: 13% PDB header:lyase Chain: F: PDB Molecule:pa4872 oxaloacetate decarboxylase; PDBTitle: crystal structure of oxaloacetate decarboxylase from pseudomonas2 aeruginosa (pa4872) in complex with oxalate and mg2+. Phyre2 PDB 2qiw chain A Region: 10 - 116 Aligned: 88 Modelled: 97 Confidence: 46.3% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:pep phosphonomutase; PDBTitle: crystal structure of a putative phosphoenolpyruvate phosphonomutase2 (ncgl1015, cgl1060) from corynebacterium glutamicum atcc 13032 at3 1.80 a resolution Phyre2 PDB 1mum chain A Region: 10 - 118 Aligned: 92 Modelled: 109 Confidence: 45.7% Identity: 22% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Phosphoenolpyruvate mutase/Isocitrate lyase-like Phyre2 PDB 2ze3 chain A Region: 10 - 116 Aligned: 91 Modelled: 96 Confidence: 41.8% Identity: 13% PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus Phyre2 PDB 2hjp chain A Region: 10 - 111 Aligned: 85 Modelled: 92 Confidence: 40.4% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++ Phyre2 PDB 3irv chain A Region: 62 - 116 Aligned: 55 Modelled: 55 Confidence: 40.2% Identity: 7% PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a Phyre2 PDB 3ih1 chain A Region: 10 - 111 Aligned: 85 Modelled: 90 Confidence: 40.1% Identity: 19% PDB header:lyase Chain: A: PDB Molecule:methylisocitrate lyase; PDBTitle: crystal structure of carboxyvinyl-carboxyphosphonate phosphorylmutase2 from bacillus anthracis Phyre2 PDB 3eef chain A Region: 73 - 116 Aligned: 44 Modelled: 44 Confidence: 39.7% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum Phyre2 PDB 3kl2 chain K Region: 73 - 116 Aligned: 44 Modelled: 44 Confidence: 35.9% Identity: 16% PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis Phyre2 1 d1xrha_ 2 c1vbiA_ 3 c1z2iA_ 4 c3i0pA_ 5 c2g8yB_ 6 d1rfma_ 7 c1wtjB_ 8 d1nxua_ 9 c3uoeB_ 10 c1v9nA_ 11 d2ebfx2 12 c3b8iF_ 13 c2qiwA_ 14 d1muma_ 15 c2ze3A_ 16 c2hjpA_ 17 c3irvA_ 18 c3ih1A_ 19 c3eefA_ 20 c3kl2K_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1xrha_ 100.0 96 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 2 c1vbiA_ 100.0 36 PDB header:oxidoreductase Chain: A: PDB Molecule:type 2 malate/lactate dehydrogenase; PDBTitle: crystal structure of type 2 malate/lactate dehydrogenase from thermus2 thermophilus hb8 3 c1z2iA_ 100.0 27 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of agrobacterium tumefaciens malate2 dehydrogenase, new york structural genomics consortium 4 c3i0pA_ 100.0 27 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of malate dehydrogenase from entamoeba histolytica 5 c2g8yB_ 100.0 28 PDB header:oxidoreductase Chain: B: PDB Molecule:malate/l-lactate dehydrogenases; PDBTitle: the structure of a putative malate/lactate dehydrogenase from e. coli. 6 d1rfma_ 100.0 34 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 7 c1wtjB_ 100.0 30 PDB header:oxidoreductase Chain: B: PDB Molecule:ureidoglycolate dehydrogenase; PDBTitle: crystal structure of delta1-piperideine-2-carboxylate2 reductase from pseudomonas syringae pvar.tomato 8 d1nxua_ 100.0 22 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 9 c3uoeB_ 100.0 30 PDB header:oxidoreductase Chain: B: PDB Molecule:dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from sinorhizobium meliloti 10 c1v9nA_ 100.0 34 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: structure of malate dehydrogenase from pyrococcus horikoshii ot3 11 d2ebfx2 54.3 18 Fold:EreA/ChaN-like Superfamily:EreA/ChaN-like Family:PMT domain-like 12 c3b8iF_ 50.4 13 PDB header:lyase Chain: F: PDB Molecule:pa4872 oxaloacetate decarboxylase; PDBTitle: crystal structure of oxaloacetate decarboxylase from pseudomonas2 aeruginosa (pa4872) in complex with oxalate and mg2+. 13 c2qiwA_ 46.3 13 PDB header:transferase Chain: A: PDB Molecule:pep phosphonomutase; PDBTitle: crystal structure of a putative phosphoenolpyruvate phosphonomutase2 (ncgl1015, cgl1060) from corynebacterium glutamicum atcc 13032 at3 1.80 a resolution 14 d1muma_ 45.7 22 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 15 c2ze3A_ 41.8 13 PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus 16 c2hjpA_ 40.4 13 PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++ 17 c3irvA_ 40.2 7 PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a 18 c3ih1A_ 40.1 19 PDB header:lyase Chain: A: PDB Molecule:methylisocitrate lyase; PDBTitle: crystal structure of carboxyvinyl-carboxyphosphonate phosphorylmutase2 from bacillus anthracis 19 c3eefA_ 39.7 18 PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum 20 c3kl2K_ 35.9 16 PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis 21 c3eooL_ not modelled 31.1 17 PDB header:lyase Chain: L: PDB Molecule:methylisocitrate lyase; PDBTitle: 2.9a crystal structure of methyl-isocitrate lyase from2 burkholderia pseudomallei 22 d1nf9a_ not modelled 29.2 7 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 23 c3ot4F_ not modelled 29.0 22 PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf 24 c3fa4D_ not modelled 27.4 18 PDB header:lyase Chain: D: PDB Molecule:2,3-dimethylmalate lyase; PDBTitle: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate2 lyase superfamily member, triclinic crystal form 25 c2b34C_ not modelled 27.3 10 PDB header:hydrolase Chain: C: PDB Molecule:mar1 ribonuclease; PDBTitle: structure of mar1 ribonuclease from caenorhabditis elegans 26 d1nbaa_ not modelled 26.6 18 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 27 c1zlpA_ not modelled 26.5 21 PDB header:lyase Chain: A: PDB Molecule:petal death protein; PDBTitle: petal death protein psr132 with cysteine-linked glutaraldehyde forming2 a thiohemiacetal adduct 28 c1e0mA_ not modelled 25.7 29 PDB header:de novo protein Chain: A: PDB Molecule:wwprototype; PDBTitle: prototype ww domain 29 c1yiuA_ not modelled 25.1 36 PDB header:ligase Chain: A: PDB Molecule:itchy e3 ubiquitin protein ligase; PDBTitle: itch e3 ubiquitin ligase ww3 domain 30 c2uygF_ not modelled 25.0 21 PDB header:lyase Chain: F: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystallogaphic structure of the typeii 3-dehydroquinase2 from thermus thermophilus 31 c3l4hA_ not modelled 24.0 17 PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase hecw1; PDBTitle: helical box domain and second ww domain of the human e3 ubiquitin-2 protein ligase hecw1 32 c3bzrA_ not modelled 23.9 18 PDB header:membrane protein, protein transport Chain: A: PDB Molecule:escu; PDBTitle: crystal structure of escu c-terminal domain with n262d mutation, space2 group p 41 21 2 33 d3bzra1 not modelled 23.9 18 Fold:EscU C-terminal domain-like Superfamily:EscU C-terminal domain-like Family:EscU C-terminal domain-like 34 d1vp8a_ not modelled 23.1 13 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 35 c1bmxA_ not modelled 22.8 22 PDB header:viral protein Chain: A: PDB Molecule:human immunodeficiency virus type 1 capsid; PDBTitle: hiv-1 capsid protein major homology region peptide analog,2 nmr, 8 structures 36 c2ysbA_ not modelled 22.7 18 PDB header:protein binding Chain: A: PDB Molecule:salvador homolog 1 protein; PDBTitle: solution structure of the first ww domain from the mouse2 salvador homolog 1 protein (sav1) 37 c3t7yB_ not modelled 22.4 20 PDB header:protein transport Chain: B: PDB Molecule:yop proteins translocation protein u; PDBTitle: structure of an autocleavage-inactive mutant of the cytoplasmic domain2 of ct091, the yscu homologue of chlamydia trachomatis 38 d1bdga1 not modelled 22.2 13 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Hexokinase 39 c1ymzA_ not modelled 22.1 29 PDB header:unknown function Chain: A: PDB Molecule:cc45; PDBTitle: cc45, an artificial ww domain designed using statistical2 coupling analysis 40 c2ysdA_ not modelled 21.6 33 PDB header:protein binding Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz PDBTitle: solution structure of the first ww domain from the human2 membrane-associated guanylate kinase, ww and pdz domain-3 containing protein 1. magi-1 41 c3hb7G_ not modelled 21.1 7 PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a 42 d1f8ab1 not modelled 20.3 20 Fold:WW domain-like Superfamily:WW domain Family:WW domain 43 c2jlhA_ not modelled 20.2 23 PDB header:protein transport Chain: A: PDB Molecule:yop proteins translocation protein u; PDBTitle: crystal structure of the cytoplasmic domain of yersinia2 pestis yscu n263a mutant 44 c1wr7A_ not modelled 19.8 33 PDB header:ligase Chain: A: PDB Molecule:nedd4-2; PDBTitle: solution structure of the third ww domain of nedd4-2 45 d2csua3 not modelled 19.8 11 Fold:Flavodoxin-like Superfamily:Succinyl-CoA synthetase domains Family:Succinyl-CoA synthetase domains 46 d1yaca_ not modelled 19.7 9 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 47 d1ujqa_ not modelled 19.5 18 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 48 d1t57a_ not modelled 19.4 16 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 49 c2hg2A_ not modelled 19.4 14 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase a; PDBTitle: structure of lactaldehyde dehydrogenase 50 d1k9ra_ not modelled 18.9 27 Fold:WW domain-like Superfamily:WW domain Family:WW domain 51 c2djyA_ not modelled 18.9 21 PDB header:ligase/signaling protein Chain: A: PDB Molecule:smad ubiquitination regulatory factor 2; PDBTitle: solution structure of smurf2 ww3 domain-smad7 py peptide2 complex 52 c2lawA_ not modelled 18.5 36 PDB header:signaling protein/transcription Chain: A: PDB Molecule:yorkie homolog; PDBTitle: structure of the second ww domain from human yap in complex with a2 human smad1 derived peptide 53 c3mcwA_ not modelled 17.7 11 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution 54 c1wmvA_ not modelled 17.6 28 PDB header:oxidoreductase, apoptosis Chain: A: PDB Molecule:ww domain containing oxidoreductase; PDBTitle: solution structure of the second ww domain of wwox 55 c1wr4A_ not modelled 17.5 29 PDB header:ligase Chain: A: PDB Molecule:ubiquitin-protein ligase nedd4-2; PDBTitle: solution structure of the second ww domain of nedd4-2 56 d1tk7a1 not modelled 17.2 21 Fold:WW domain-like Superfamily:WW domain Family:WW domain 57 d1j2ra_ not modelled 17.2 10 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 58 c3gveB_ not modelled 17.0 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:yfkn protein; PDBTitle: crystal structure of calcineurin-like phosphoesterase yfkn from2 bacillus subtilis 59 d2cfua2 not modelled 16.8 12 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Alkylsulfatase-like 60 c2kykA_ not modelled 16.5 36 PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog; PDBTitle: the sandwich region between two lmp2a py motif regulates the2 interaction between aip4ww2domain and py motif 61 d1a4sa_ not modelled 16.1 19 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 62 c2jmfA_ not modelled 16.0 20 PDB header:ligase/signaling protein Chain: A: PDB Molecule:e3 ubiquitin-protein ligase suppressor of deltex; PDBTitle: solution structure of the su(dx) ww4- notch py peptide2 complex 63 d2jmfa1 not modelled 14.9 21 Fold:WW domain-like Superfamily:WW domain Family:WW domain 64 d1i5hw_ not modelled 14.5 20 Fold:WW domain-like Superfamily:WW domain Family:WW domain 65 d3djba1 not modelled 14.4 17 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 66 c2ez5W_ not modelled 14.0 33 PDB header:signalling protein,ligase Chain: W: PDB Molecule:e3 ubiquitin-protein ligase nedd4; PDBTitle: solution structure of the dnedd4 ww3* domain- comm lpsy2 peptide complex 67 d3ci0k2 not modelled 14.0 19 Fold:SAM domain-like Superfamily:GspK insert domain-like Family:GspK insert domain-like 68 c2fq1A_ not modelled 13.9 7 PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains 69 c2h0rD_ not modelled 13.8 7 PDB header:hydrolase Chain: D: PDB Molecule:nicotinamidase; PDBTitle: structure of the yeast nicotinamidase pnc1p 70 d1wjfa_ not modelled 13.4 16 Fold:DNA/RNA-binding 3-helical bundle Superfamily:N-terminal Zn binding domain of HIV integrase Family:N-terminal Zn binding domain of HIV integrase 71 c2yshA_ not modelled 13.4 20 PDB header:protein binding Chain: A: PDB Molecule:growth-arrest-specific protein 7; PDBTitle: solution structure of the ww domain from the human growth-2 arrest-specific protein 7, gas-7 72 c2nu9E_ not modelled 13.0 18 PDB header:ligase Chain: E: PDB Molecule:succinyl-coa synthetase beta chain; PDBTitle: c123at mutant of e. coli succinyl-coa synthetase2 orthorhombic crystal form 73 c3oqpA_ not modelled 12.9 15 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution 74 c2k29A_ not modelled 12.7 19 PDB header:transcription Chain: A: PDB Molecule:antitoxin relb; PDBTitle: structure of the dbd domain of e. coli antitoxin relb 75 d1sgma2 not modelled 12.4 16 Fold:Tetracyclin repressor-like, C-terminal domain Superfamily:Tetracyclin repressor-like, C-terminal domain Family:Tetracyclin repressor-like, C-terminal domain 76 c3jz4C_ not modelled 12.0 18 PDB header:oxidoreductase Chain: C: PDB Molecule:succinate-semialdehyde dehydrogenase [nadp+]; PDBTitle: crystal structure of e. coli nadp dependent enzyme 77 c2pmzF_ not modelled 11.5 23 PDB header:translation, transferase Chain: F: PDB Molecule:dna-directed rna polymerase subunit f; PDBTitle: archaeal rna polymerase from sulfolobus solfataricus 78 c3ifgH_ not modelled 11.3 19 PDB header:oxidoreductase Chain: H: PDB Molecule:succinate-semialdehyde dehydrogenase (nadp+); PDBTitle: crystal structure of succinate-semialdehyde dehydrogenase from2 burkholderia pseudomallei, part 1 of 2 79 c3k2wD_ not modelled 11.2 15 PDB header:oxidoreductase Chain: D: PDB Molecule:betaine-aldehyde dehydrogenase; PDBTitle: crystal structure of betaine-aldehyde dehydrogenase from2 pseudoalteromonas atlantica t6c 80 d1lvaa3 not modelled 11.2 18 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:C-terminal fragment of elongation factor SelB 81 c2kxqA_ not modelled 11.1 13 PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf2; PDBTitle: solution structure of smurf2 ww2 and ww3 bound to smad7 py motif2 containing peptide 82 c2d4eB_ not modelled 11.0 16 PDB header:oxidoreductase Chain: B: PDB Molecule:5-carboxymethyl-2-hydroxymuconate semialdehyde PDBTitle: crystal structure of the hpcc from thermus thermophilus hb8 83 c2l4jA_ not modelled 10.7 27 PDB header:transcription Chain: A: PDB Molecule:yes-associated protein 2 (yap2); PDBTitle: yap ww2 84 d1f61a_ not modelled 10.6 17 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 85 c2ve5H_ not modelled 10.3 18 PDB header:oxidoreductase Chain: H: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystallographic structure of betaine aldehyde2 dehydrogenase from pseudomonas aeruginosa 86 d1o5ha_ not modelled 10.2 25 Fold:Methenyltetrahydrofolate cyclohydrolase-like Superfamily:Methenyltetrahydrofolate cyclohydrolase-like Family:Methenyltetrahydrofolate cyclohydrolase-like 87 c2ysgA_ not modelled 10.1 29 PDB header:protein binding Chain: A: PDB Molecule:syntaxin-binding protein 4; PDBTitle: solution structure of the ww domain from the human syntaxin-2 binding protein 4 88 c3iwkB_ not modelled 10.0 19 PDB header:oxidoreductase Chain: B: PDB Molecule:aminoaldehyde dehydrogenase; PDBTitle: crystal structure of aminoaldehyde dehydrogenase 1 from2 pisum sativum (psamadh1) 89 d2f21a1 not modelled 9.9 23 Fold:WW domain-like Superfamily:WW domain Family:WW domain 90 c2lazA_ not modelled 9.9 14 PDB header:signaling protein/transcription Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1; PDBTitle: structure of the first ww domain of human smurf1 in complex with a2 mono-phosphorylated human smad1 derived peptide 91 c2lb0A_ not modelled 9.9 14 PDB header:signaling protein/transcription Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1; PDBTitle: structure of the first ww domain of human smurf1 in complex with a di-2 phosphorylated human smad1 derived peptide 92 c3hazA_ not modelled 9.9 22 PDB header:oxidoreductase Chain: A: PDB Molecule:proline dehydrogenase; PDBTitle: crystal structure of bifunctional proline utilization a2 (puta) protein 93 c2a67C_ not modelled 9.8 7 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein 94 d1wdja_ not modelled 9.8 14 Fold:Restriction endonuclease-like Superfamily:Restriction endonuclease-like Family:Hypothetical protein TT1808 (TTHA1514) 95 c3lqyA_ not modelled 9.7 20 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase hydrolase; PDBTitle: crystal structure of putative isochorismatase hydrolase from2 oleispira antarctica 96 c2cfuA_ not modelled 9.6 12 PDB header:hydrolase Chain: A: PDB Molecule:sdsa1; PDBTitle: crystal structure of sdsa1, an alkylsulfatase from2 pseudomonas aeruginosa, in complex with 1-decane-sulfonic-3 acid. 97 c2dmvA_ not modelled 9.5 33 PDB header:ligase Chain: A: PDB Molecule:itchy homolog e3 ubiquitin protein ligase; PDBTitle: solution structure of the second ww domain of itchy homolog2 e3 ubiquitin protein ligase (itch) 98 c2ysfA_ not modelled 9.5 27 PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog; PDBTitle: solution structure of the fourth ww domain from the human2 e3 ubiquitin-protein ligase itchy homolog, itch 99 c2w8qA_ not modelled 9.4 25 PDB header:oxidoreductase Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase, PDBTitle: the crystal structure of human ssadh in complex with ssa.

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0