Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	V	L	H	N	R	I	S	N	D	A	L	K	A	K	M	L	A	E	S	E	P	R	T	T	I	S	F	Y	K	Y	F	H	I	A	D	P	K	A	T	R	D	A	L	Y	Q	L	F	T	A	L	N	V	F	G	R	V	Y	L
Secondary structure
SS confidence
Disorder		?	?	?	?		?	?	?										?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	H	E	G	I	N	A	Q	I	S	V	P	A	S	N	V	E	T	F	R	A	Q	L	Y	A	F	D	P	A	L	E	G	L	R	L	N	I	A	L	D	D	D	G	K	S	F	W	V	L	R	M	K	V	R	D	R	I	V	A	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	I	D	D	P	H	F	D	A	S	N	V	G	E	Y	L	Q	A	A	E	V	N	A	M	L	D	D	P	D	A	L	F	I	D	M	R	N	H	Y	E	Y	E	V	G	H	F	E	N	A	L	E	I	P	A	D	T	F	R	E	Q
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	P	K	A	V	E	M	M	Q	A	H	K	D	K	K	I	V	M	Y	C	T	G	G	I	R	C	E	K	A	S	A	W	M	K	H	N	G	F	N	K	V	W	H	I	E	G	G	I	I	E	Y	A	R	K	A	R	E	Q	G	L
Secondary structure
SS confidence
Disorder																																							?																	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	V	R	F	I	G	K	N	F	V	F	D	E	R	M	G	E	R	I	S	D	E	I	I	A	H	C	H	Q	C	G	A	P	C	D	S	H	T	N	C	K	N	D	G	C	H	L	L	F	I	Q	C	P	V	C	A	E	K	Y	K
Secondary structure
SS confidence
Disorder															?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence		G	C	C	S	E	I	C	C	E	E	S	A	L	P	P	E	E	Q	R	R	R	R	A	G	R	E	N	G	N	K	I	F	N	K	S	R	G	R	L	N	T	T	L	C	I	P	D	P	T	E
Secondary structure
SS confidence
Disorder												?	?	?	?													?	?	?	?	?	?	?	?			?	?						?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2j6p chain F Region: 134 - 253 Aligned: 119 Modelled: 119 Confidence: 99.9% Identity: 21% PDB header:oxidoreductase Chain: F: PDB Molecule:sb(v)-as(v) reductase; PDBTitle: structure of as-sb reductase from leishmania major Phyre2 PDB 3i2v chain A Region: 136 - 243 Aligned: 107 Modelled: 108 Confidence: 99.8% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:adenylyltransferase and sulfurtransferase mocs3; PDBTitle: crystal structure of human mocs3 rhodanese-like domain Phyre2 PDB 3tp9 chain B Region: 136 - 234 Aligned: 93 Modelled: 99 Confidence: 99.8% Identity: 26% PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase and rhodanese domain protein; PDBTitle: crystal structure of alicyclobacillus acidocaldarius protein with2 beta-lactamase and rhodanese domains Phyre2 PDB 1c25 chain A Region: 134 - 237 Aligned: 104 Modelled: 104 Confidence: 99.8% Identity: 22% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Cell cycle control phosphatase, catalytic domain Phyre2 PDB 3d1p chain A Region: 134 - 238 Aligned: 105 Modelled: 105 Confidence: 99.8% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase yor285w; PDBTitle: atomic resolution structure of uncharacterized protein from2 saccharomyces cerevisiae Phyre2 PDB 3f4a chain A Region: 134 - 245 Aligned: 111 Modelled: 112 Confidence: 99.8% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein ygr203w; PDBTitle: structure of ygr203w, a yeast protein tyrosine phosphatase2 of the rhodanese family Phyre2 PDB 2hhg chain A Region: 115 - 234 Aligned: 120 Modelled: 120 Confidence: 99.8% Identity: 25% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein rpa3614; PDBTitle: structure of protein of unknown function rpa3614, possible tyrosine2 phosphatase, from rhodopseudomonas palustris cga009 Phyre2 PDB 1yt8 chain A domain 4 Region: 136 - 231 Aligned: 91 Modelled: 96 Confidence: 99.8% Identity: 22% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Multidomain sulfurtransferase (rhodanese) Phyre2 PDB 1yt8 chain A domain 1 Region: 134 - 234 Aligned: 97 Modelled: 101 Confidence: 99.8% Identity: 21% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Multidomain sulfurtransferase (rhodanese) Phyre2 PDB 3ilm chain D Region: 137 - 234 Aligned: 93 Modelled: 98 Confidence: 99.8% Identity: 23% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:alr3790 protein; PDBTitle: crystal structure of the alr3790 protein from anabaena sp. northeast2 structural genomics consortium target nsr437h Phyre2 PDB 3foj chain A Region: 133 - 231 Aligned: 92 Modelled: 97 Confidence: 99.8% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of ssp1007 from staphylococcus2 saprophyticus subsp. saprophyticus. northeast structural3 genomics target syr101a. Phyre2 PDB 1gmx chain A Region: 134 - 238 Aligned: 98 Modelled: 105 Confidence: 99.8% Identity: 20% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Single-domain sulfurtransferase Phyre2 PDB 3icr chain A Region: 129 - 238 Aligned: 102 Modelled: 110 Confidence: 99.8% Identity: 26% PDB header:oxidoreductase Chain: A: PDB Molecule:coenzyme a-disulfide reductase; PDBTitle: crystal structure of oxidized bacillus anthracis coadr-rhd Phyre2 PDB 1ymk chain A domain 1 Region: 116 - 237 Aligned: 120 Modelled: 122 Confidence: 99.8% Identity: 20% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Cell cycle control phosphatase, catalytic domain Phyre2 PDB 1yt8 chain A Region: 121 - 234 Aligned: 108 Modelled: 114 Confidence: 99.8% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:thiosulfate sulfurtransferase; PDBTitle: crystal structure of thiosulfate sulfurtransferase from pseudomonas2 aeruginosa Phyre2 PDB 2dcq chain A Region: 131 - 234 Aligned: 104 Modelled: 104 Confidence: 99.8% Identity: 15% PDB header:unknown function Chain: A: PDB Molecule:putative protein at4g01050; PDBTitle: fully automated nmr structure determination of the2 rhodanese homology domain at4g01050(175-295) from3 arabidopsis thaliana Phyre2 PDB 2fsx chain A Region: 136 - 245 Aligned: 109 Modelled: 110 Confidence: 99.8% Identity: 14% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:cog0607: rhodanese-related sulfurtransferase; PDBTitle: crystal structure of rv0390 from m. tuberculosis Phyre2 PDB 1yt8 chain A domain 2 Region: 136 - 234 Aligned: 95 Modelled: 99 Confidence: 99.8% Identity: 18% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Multidomain sulfurtransferase (rhodanese) Phyre2 PDB 1qxn chain A Region: 134 - 234 Aligned: 100 Modelled: 101 Confidence: 99.8% Identity: 19% Fold: Rhodanese/Cell cycle control phosphatase Superfamily: Rhodanese/Cell cycle control phosphatase Family: Single-domain sulfurtransferase Phyre2 PDB 1e0c chain A Region: 136 - 234 Aligned: 99 Modelled: 99 Confidence: 99.8% Identity: 20% PDB header:sulfurtransferase Chain: A: PDB Molecule:sulfurtransferase; PDBTitle: sulfurtransferase from azotobacter vinelandii Phyre2 PDB 1urr chain A Region: 41 - 113 Aligned: 73 Modelled: 73 Confidence: 95.8% Identity: 15% Fold: Ferredoxin-like Superfamily: Acylphosphatase/BLUF domain-like Family: Acylphosphatase-like Phyre2 PDB 2gv1 chain A Region: 41 - 112 Aligned: 72 Modelled: 72 Confidence: 95.6% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:probable acylphosphatase; PDBTitle: nmr solution structure of the acylphosphatase from2 eschaerichia coli Phyre2 PDB 2acy chain A Region: 41 - 112 Aligned: 72 Modelled: 72 Confidence: 95.5% Identity: 15% Fold: Ferredoxin-like Superfamily: Acylphosphatase/BLUF domain-like Family: Acylphosphatase-like Phyre2 PDB 3br8 chain A Region: 41 - 113 Aligned: 73 Modelled: 73 Confidence: 94.9% Identity: 10% PDB header:hydrolase Chain: A: PDB Molecule:probable acylphosphatase; PDBTitle: crystal structure of acylphosphatase from bacillus subtilis Phyre2 PDB 1aps chain A Region: 41 - 113 Aligned: 73 Modelled: 73 Confidence: 94.4% Identity: 12% Fold: Ferredoxin-like Superfamily: Acylphosphatase/BLUF domain-like Family: Acylphosphatase-like Phyre2 PDB 1ulr chain A Region: 41 - 111 Aligned: 70 Modelled: 70 Confidence: 94.4% Identity: 14% Fold: Ferredoxin-like Superfamily: Acylphosphatase/BLUF domain-like Family: Acylphosphatase-like Phyre2 PDB 3i32 chain A Region: 181 - 276 Aligned: 94 Modelled: 94 Confidence: 77.4% Identity: 7% PDB header:rna binding protein,hydrolase Chain: A: PDB Molecule:heat resistant rna dependent atpase; PDBTitle: dimeric structure of a hera helicase fragment including the c-terminal2 reca domain, the dimerization domain, and the rna binding domain Phyre2 PDB 1dvp chain A Region: 228 - 295 Aligned: 66 Modelled: 66 Confidence: 63.3% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine PDBTitle: crystal structure of the vhs and fyve tandem domains of hrs,2 a protein involved in membrane trafficking and signal3 transduction Phyre2 1 c2j6pF_ 2 c3i2vA_ 3 c3tp9B_ 4 d1c25a_ 5 c3d1pA_ 6 c3f4aA_ 7 c2hhgA_ 8 d1yt8a4 9 d1yt8a1 10 c3ilmD_ 11 c3fojA_ 12 d1gmxa_ 13 c3icrA_ 14 d1ymka1 15 c1yt8A_ 16 c2dcqA_ 17 c2fsxA_ 18 d1yt8a2 19 d1qxna_ 20 c1e0cA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 d1urra_ 61 62 c2gv1A_ 63 64 d2acya_ 65 c3br8A_ 66 67 d1apsa_ 68 d1ulra_ 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 c3i32A_ 89 90 91 92 93 94 95 96 97 98 99 c1dvpA_ 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2j6pF_ 99.9 21 PDB header:oxidoreductase Chain: F: PDB Molecule:sb(v)-as(v) reductase; PDBTitle: structure of as-sb reductase from leishmania major 2 c3i2vA_ 99.8 21 PDB header:transferase Chain: A: PDB Molecule:adenylyltransferase and sulfurtransferase mocs3; PDBTitle: crystal structure of human mocs3 rhodanese-like domain 3 c3tp9B_ 99.8 26 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase and rhodanese domain protein; PDBTitle: crystal structure of alicyclobacillus acidocaldarius protein with2 beta-lactamase and rhodanese domains 4 d1c25a_ 99.8 22 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Cell cycle control phosphatase, catalytic domain 5 c3d1pA_ 99.8 17 PDB header:transferase Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase yor285w; PDBTitle: atomic resolution structure of uncharacterized protein from2 saccharomyces cerevisiae 6 c3f4aA_ 99.8 15 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein ygr203w; PDBTitle: structure of ygr203w, a yeast protein tyrosine phosphatase2 of the rhodanese family 7 c2hhgA_ 99.8 25 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein rpa3614; PDBTitle: structure of protein of unknown function rpa3614, possible tyrosine2 phosphatase, from rhodopseudomonas palustris cga009 8 d1yt8a4 99.8 22 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 9 d1yt8a1 99.8 21 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 10 c3ilmD_ 99.8 23 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:alr3790 protein; PDBTitle: crystal structure of the alr3790 protein from anabaena sp. northeast2 structural genomics consortium target nsr437h 11 c3fojA_ 99.8 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of ssp1007 from staphylococcus2 saprophyticus subsp. saprophyticus. northeast structural3 genomics target syr101a. 12 d1gmxa_ 99.8 20 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Single-domain sulfurtransferase 13 c3icrA_ 99.8 26 PDB header:oxidoreductase Chain: A: PDB Molecule:coenzyme a-disulfide reductase; PDBTitle: crystal structure of oxidized bacillus anthracis coadr-rhd 14 d1ymka1 99.8 20 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Cell cycle control phosphatase, catalytic domain 15 c1yt8A_ 99.8 14 PDB header:transferase Chain: A: PDB Molecule:thiosulfate sulfurtransferase; PDBTitle: crystal structure of thiosulfate sulfurtransferase from pseudomonas2 aeruginosa 16 c2dcqA_ 99.8 15 PDB header:unknown function Chain: A: PDB Molecule:putative protein at4g01050; PDBTitle: fully automated nmr structure determination of the2 rhodanese homology domain at4g01050(175-295) from3 arabidopsis thaliana 17 c2fsxA_ 99.8 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:cog0607: rhodanese-related sulfurtransferase; PDBTitle: crystal structure of rv0390 from m. tuberculosis 18 d1yt8a2 99.8 18 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 19 d1qxna_ 99.8 19 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Single-domain sulfurtransferase 20 c1e0cA_ 99.8 20 PDB header:sulfurtransferase Chain: A: PDB Molecule:sulfurtransferase; PDBTitle: sulfurtransferase from azotobacter vinelandii 21 c3emeA_ not modelled 99.7 28 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:rhodanese-like domain protein; PDBTitle: crystal structure of rhodanese-like domain protein from2 staphylococcus aureus 22 c3aaxB_ not modelled 99.7 19 PDB header:transferase Chain: B: PDB Molecule:putative thiosulfate sulfurtransferase; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase2 cysa3 (rv3117) from mycobacterium tuberculosis: monoclinic3 form 23 c3gk5A_ not modelled 99.7 25 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized rhodanese-related protein PDBTitle: crystal structure of rhodanese-related protein (tvg0868615)2 from thermoplasma volcanium, northeast structural genomics3 consortium target tvr109a 24 c1urhA_ not modelled 99.7 27 PDB header:transferase Chain: A: PDB Molecule:3-mercaptopyruvate sulfurtransferase; PDBTitle: the "rhodanese" fold and catalytic mechanism of2 3-mercaptopyruvate sulfotransferases: crystal structure3 of ssea from escherichia coli 25 d1yt8a3 not modelled 99.7 15 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 26 c3op3A_ not modelled 99.7 23 PDB header:hydrolase Chain: A: PDB Molecule:m-phase inducer phosphatase 3; PDBTitle: crystal structure of cell division cycle 25c protein isoform a from2 homo sapiens 27 d1tq1a_ not modelled 99.7 22 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Single-domain sulfurtransferase 28 c3hzuA_ not modelled 99.7 20 PDB header:transferase Chain: A: PDB Molecule:thiosulfate sulfurtransferase ssea; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase ssea2 (rhodanese) from mycobacterium tuberculosis 29 c3g5jA_ not modelled 99.7 27 PDB header:nucleotide binding protein Chain: A: PDB Molecule:putative atp/gtp binding protein; PDBTitle: crystal structure of n-terminal domain of putative atp/gtp binding2 protein from clostridium difficile 630 30 c2uzqE_ not modelled 99.7 21 PDB header:hydrolase Chain: E: PDB Molecule:m-phase inducer phosphatase 2; PDBTitle: protein phosphatase, new crystal form 31 c3k9rA_ not modelled 99.7 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:alr3790 protein; PDBTitle: x-ray structure of the rhodanese-like domain of the alr3790 protein2 from anabaena sp. northeast structural genomics consortium target3 nsr437c. 32 c3ntaA_ not modelled 99.7 28 PDB header:oxidoreductase Chain: A: PDB Molecule:fad-dependent pyridine nucleotide-disulphide PDBTitle: structure of the shewanella loihica pv-4 nadh-dependent persulfide2 reductase 33 d1e0ca1 not modelled 99.7 20 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 34 d1uara2 not modelled 99.7 28 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 35 c1uarA_ not modelled 99.7 24 PDB header:transferase Chain: A: PDB Molecule:rhodanese; PDBTitle: crystal structure of rhodanese from thermus thermophilus hb8 36 c1boiA_ not modelled 99.7 16 PDB header:transferase Chain: A: PDB Molecule:rhodanese; PDBTitle: n-terminally truncated rhodanese 37 c3ippA_ not modelled 99.7 20 PDB header:transferase Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase ynje; PDBTitle: crystal structure of sulfur-free ynje 38 d1t3ka_ not modelled 99.7 16 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Cell cycle control phosphatase, catalytic domain 39 c3olhA_ not modelled 99.7 20 PDB header:transferase Chain: A: PDB Molecule:3-mercaptopyruvate sulfurtransferase; PDBTitle: human 3-mercaptopyruvate sulfurtransferase 40 c2jtqA_ not modelled 99.7 25 PDB header:transferase Chain: A: PDB Molecule:phage shock protein e; PDBTitle: rhodanese from e.coli 41 d1rhsa1 not modelled 99.7 15 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 42 c1wv9B_ not modelled 99.6 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:rhodanese homolog tt1651; PDBTitle: crystal structure of rhodanese homolog tt1651 from an2 extremely thermophilic bacterium thermus thermophilus hb8 43 c3nhvE_ not modelled 99.6 26 PDB header:structural genomics, unknown function Chain: E: PDB Molecule:bh2092 protein; PDBTitle: crystal structure of bh2092 protein from bacillus halodurans,2 northeast structural genomics consortium target bhr228f 44 c2k0zA_ not modelled 99.6 29 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein hp1203; PDBTitle: solution nmr structure of protein hp1203 from helicobacter pylori2 26695. northeast structural genomics consortium (nesg) target3 pt1/ontario center for structural proteomics target hp1203 45 d1urha1 not modelled 99.6 24 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 46 d1e0ca2 not modelled 99.6 24 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 47 d1okga2 not modelled 99.6 21 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 48 d1rhsa2 not modelled 99.6 20 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 49 d1uara1 not modelled 99.6 24 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 50 c2vswB_ not modelled 99.6 22 PDB header:hydrolase Chain: B: PDB Molecule:dual specificity protein phosphatase 16; PDBTitle: the structure of the rhodanese domain of the human dual2 specificity phosphatase 16 51 c3r2uC_ not modelled 99.4 24 PDB header:hydrolase Chain: C: PDB Molecule:metallo-beta-lactamase family protein; PDBTitle: 2.1 angstrom resolution crystal structure of metallo-beta-lactamase2 from staphylococcus aureus subsp. aureus col 52 d1urha2 not modelled 99.4 20 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 53 d1okga1 not modelled 99.4 19 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 54 c2oucB_ not modelled 99.4 16 PDB header:hydrolase Chain: B: PDB Molecule:dual specificity protein phosphatase 10; PDBTitle: crystal structure of the map kinase binding domain of mkp5 55 d2gwfa1 not modelled 99.4 16 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Ubiquitin carboxyl-terminal hydrolase 8, USP8 56 c2eg4B_ not modelled 99.4 18 PDB header:transferase Chain: B: PDB Molecule:probable thiosulfate sulfurtransferase; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase 57 d1whba_ not modelled 99.4 15 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Ubiquitin carboxyl-terminal hydrolase 8, USP8 58 c1okgA_ not modelled 99.3 20 PDB header:transferase Chain: A: PDB Molecule:possible 3-mercaptopyruvate sulfurtransferase; PDBTitle: 3-mercaptopyruvate sulfurtransferase from leishmania major 59 d1hzma_ not modelled 99.3 19 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Cell cycle control phosphatase, catalytic domain 60 d1urra_ 95.8 15 Fold:Ferredoxin-like Superfamily:Acylphosphatase/BLUF domain-like Family:Acylphosphatase-like 61 c3flhC_ not modelled 95.7 24 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein lp_1913; PDBTitle: crystal structure of lp_1913 protein from lactobacillus2 plantarum,northeast structural genomics consortium target3 lpr140b 62 c2gv1A_ 95.6 14 PDB header:hydrolase Chain: A: PDB Molecule:probable acylphosphatase; PDBTitle: nmr solution structure of the acylphosphatase from2 eschaerichia coli 63 d1d5ra2 not modelled 95.5 10 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 64 d2acya_ 95.5 15 Fold:Ferredoxin-like Superfamily:Acylphosphatase/BLUF domain-like Family:Acylphosphatase-like 65 c3br8A_ 94.9 10 PDB header:hydrolase Chain: A: PDB Molecule:probable acylphosphatase; PDBTitle: crystal structure of acylphosphatase from bacillus subtilis 66 c3rgqA_ not modelled 94.6 15 PDB header:hydrolase Chain: A: PDB Molecule:protein-tyrosine phosphatase mitochondrial 1; PDBTitle: crystal structure of ptpmt1 in complex with pi(5)p 67 d1apsa_ 94.4 12 Fold:Ferredoxin-like Superfamily:Acylphosphatase/BLUF domain-like Family:Acylphosphatase-like 68 d1ulra_ 94.4 14 Fold:Ferredoxin-like Superfamily:Acylphosphatase/BLUF domain-like Family:Acylphosphatase-like 69 c3gxgA_ not modelled 94.3 13 PDB header:hydrolase Chain: A: PDB Molecule:putative phosphatase (duf442); PDBTitle: crystal structure of putative phosphatase (duf442) (yp_001181608.1)2 from shewanella putrefaciens cn-32 at 1.60 a resolution 70 d1w2ia_ not modelled 94.1 18 Fold:Ferredoxin-like Superfamily:Acylphosphatase/BLUF domain-like Family:Acylphosphatase-like 71 c2f46A_ not modelled 94.1 17 PDB header:hydrolase Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of a putative phosphatase (nma1982) from neisseria2 meningitidis z2491 at 1.41 a resolution 72 c2bjeA_ not modelled 94.0 11 PDB header:hydrolase Chain: A: PDB Molecule:acylphosphatase; PDBTitle: acylphosphatase from sulfolobus solfataricus. monclinic p212 space group 73 c3awfC_ not modelled 93.8 18 PDB header:hydrolase, membrane protein Chain: C: PDB Molecule:voltage-sensor containing phosphatase; PDBTitle: crystal structure of pten-like domain of ci-vsp (236-576) 74 c2imgA_ not modelled 93.5 14 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity protein phosphatase 23; PDBTitle: crystal structure of dual specificity protein phosphatase2 23 from homo sapiens in complex with ligand malate ion 75 d1xria_ not modelled 92.9 11 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 76 c1d5rA_ not modelled 92.0 10 PDB header:hydrolase Chain: A: PDB Molecule:phosphoinositide phosphotase pten; PDBTitle: crystal structure of the pten tumor suppressor 77 c1yn9B_ not modelled 88.6 17 PDB header:hydrolase Chain: B: PDB Molecule:polynucleotide 5'-phosphatase; PDBTitle: crystal structure of baculovirus rna 5'-phosphatase2 complexed with phosphate 78 d1ywfa1 not modelled 87.7 16 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Mycobacterial PtpB-like 79 c3rz2B_ not modelled 87.5 13 PDB header:hydrolase Chain: B: PDB Molecule:protein tyrosine phosphatase type iva 1; PDBTitle: crystal of prl-1 complexed with peptide 80 c1fpzF_ not modelled 87.1 13 PDB header:hydrolase Chain: F: PDB Molecule:cyclin-dependent kinase inhibitor 3; PDBTitle: crystal structure analysis of kinase associated phosphatase2 (kap) with a substitution of the catalytic site cysteine3 (cys140) to a serine 81 d1rxda_ not modelled 86.4 11 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 82 d1jl3a_ not modelled 82.4 29 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 83 d1oywa3 not modelled 81.8 19 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 84 d1fpza_ not modelled 80.7 13 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 85 c3n0aA_ not modelled 80.1 13 PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase auxilin; PDBTitle: crystal structure of auxilin (40-400) 86 c3t38B_ not modelled 79.0 18 PDB header:oxidoreductase Chain: B: PDB Molecule:arsenate reductase; PDBTitle: corynebacterium glutamicum thioredoxin-dependent arsenate reductase2 cg_arsc1' 87 c2c46B_ not modelled 78.2 13 PDB header:transferase Chain: B: PDB Molecule:mrna capping enzyme; PDBTitle: crystal structure of the human rna guanylyltransferase and2 5'-phosphatase 88 c3i32A_ 77.4 7 PDB header:rna binding protein,hydrolase Chain: A: PDB Molecule:heat resistant rna dependent atpase; PDBTitle: dimeric structure of a hera helicase fragment including the c-terminal2 reca domain, the dimerization domain, and the rna binding domain 89 c2l18A_ not modelled 77.0 26 PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: an arsenate reductase in the phosphate binding state 90 c2vxoB_ not modelled 75.1 14 PDB header:ligase Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: human gmp synthetase in complex with xmp 91 d1fuka_ not modelled 75.0 11 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 92 d1a1va2 not modelled 74.1 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RNA helicase 93 d1y4oa1 not modelled 73.8 18 Fold:Profilin-like Superfamily:Roadblock/LC7 domain Family:Roadblock/LC7 domain 94 c1oheA_ not modelled 73.1 17 PDB header:hydrolase Chain: A: PDB Molecule:cdc14b2 phosphatase; PDBTitle: structure of cdc14b phosphatase with a peptide ligand 95 d1jf8a_ not modelled 72.7 26 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 96 c2i6oA_ not modelled 72.1 16 PDB header:hydrolase Chain: A: PDB Molecule:sulfolobus solfataricus protein tyrosine PDBTitle: crystal structure of the complex of the archaeal sulfolobus2 ptp-fold phosphatase with phosphopeptides n-g-(p)y-k-n 97 d1yrxa1 not modelled 64.9 11 Fold:Ferredoxin-like Superfamily:Acylphosphatase/BLUF domain-like Family:BLUF domain 98 c3rofA_ not modelled 63.7 18 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine-phosphatase ptpa; PDBTitle: crystal structure of the s. aureus protein tyrosine phosphatase ptpa 99 c1dvpA_ 63.3 17 PDB header:transferase Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine PDBTitle: crystal structure of the vhs and fyve tandem domains of hrs,2 a protein involved in membrane trafficking and signal3 transduction 100 d1ni5a1 not modelled 63.2 14 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PP-loop ATPase 101 c1yz4A_ not modelled 62.5 10 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity phosphatase-like 15 isoform a; PDBTitle: crystal structure of dusp15 102 c2hcmA_ not modelled 62.3 13 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity protein phosphatase; PDBTitle: crystal structure of mouse putative dual specificity phosphatase2 complexed with zinc tungstate, new york structural genomics3 consortium 103 c1k97A_ not modelled 62.2 18 PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of e. coli argininosuccinate synthetase in complex2 with aspartate and citrulline 104 c3ptwA_ not modelled 61.1 14 PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: crystal structure of malonyl coa-acyl carrier protein transacylase2 from clostridium perfringens atcc 13124 105 c2f55C_ not modelled 60.2 17 PDB header:hydrolase/dna Chain: C: PDB Molecule:polyprotein; PDBTitle: two hepatitis c virus ns3 helicase domains complexed with2 the same strand of dna 106 c1oywA_ not modelled 59.9 19 PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent dna helicase; PDBTitle: structure of the recq catalytic core 107 c2jgnB_ not modelled 58.2 12 PDB header:hydrolase Chain: B: PDB Molecule:atp-dependent rna helicase ddx3x; PDBTitle: ddx3 helicase domain 108 d1gxua_ not modelled 58.2 22 Fold:Ferredoxin-like Superfamily:Acylphosphatase/BLUF domain-like Family:Acylphosphatase-like 109 c2v1xB_ not modelled 58.1 11 PDB header:hydrolase Chain: B: PDB Molecule:atp-dependent dna helicase q1; PDBTitle: crystal structure of human recq-like dna helicase 110 d1m3ga_ not modelled 58.0 10 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 111 c1wrmA_ not modelled 58.0 11 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity phosphatase 22; PDBTitle: crystal structure of jsp-1 112 d1v3aa_ not modelled 57.9 13 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 113 d2g2ja1 not modelled 57.6 10 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 114 c2fekA_ not modelled 57.6 18 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine- PDBTitle: structure of a protein tyrosine phosphatase 115 c2gi4A_ not modelled 57.5 39 PDB header:hydrolase Chain: A: PDB Molecule:possible phosphotyrosine protein phosphatase; PDBTitle: solution structure of the low molecular weight protein2 tyrosine phosphatase from campylobacter jejuni. 116 c2wmyH_ not modelled 56.6 21 PDB header:hydrolase Chain: H: PDB Molecule:putative acid phosphatase wzb; PDBTitle: crystal structure of the tyrosine phosphatase wzb from2 escherichia coli k30 in complex with sulphate. 117 c2oz5A_ not modelled 55.9 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:phosphotyrosine protein phosphatase ptpb; PDBTitle: crystal structure of mycobacterium tuberculosis protein tyrosine2 phosphatase ptpb in complex with the specific inhibitor omts 118 d2j0sa2 not modelled 54.3 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 119 d1y1la_ not modelled 54.2 22 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 120 c2cwdA_ not modelled 53.2 15 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight phosphotyrosine protein phosphatase; PDBTitle: crystal structure of tt1001 protein from thermus thermophilus hb8

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0