Email l.a.kelley@imperial.ac.uk Description P76176 Date Thu Jan 5 12:20:09 GMT 2012 Unique Job ID cd424b4f9ecebf9d

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3nxpA_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:prethrombin-1; PDBTitle: crystal structure of human prethrombin-1 2 c2b9lA_ 100.0 17 PDB header:immune system/protein binding Chain: A: PDB Molecule:prophenoloxidase activating factor; PDBTitle: crystal structure of prophenoloxidase activating factor-ii from the2 beetle holotrichia diomphalia 3 c2f83A_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:coagulation factor xi; PDBTitle: crystal structure at 2.9 angstroms resolution of human plasma2 coagulation factor xi zymogen 4 c1z8gA_ 100.0 19 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:serine protease hepsin; PDBTitle: crystal structure of the extracellular region of the transmembrane2 serine protease hepsin with covalently bound preferred substrate. 5 c1zjkA_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:mannan-binding lectin serine protease 2; PDBTitle: crystal structure of the zymogen catalytic region of human masp-2 6 c2i6sA_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:complement c2a fragment; PDBTitle: complement component c2a 7 c1rs0A_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: crystal structure analysis of the bb segment of factor b2 complexed with di-isopropyl-phosphate (dip) 8 c2ok5A_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: human complement factor b 9 c3f1sB_ 100.0 18 PDB header:hydrolase inhibitor/hydrolase Chain: B: PDB Molecule:vitamin k-dependent protein z; PDBTitle: crystal structure of protein z complexed with protein z-dependent2 inhibitor 10 d1p3ca_ 100.0 19 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Prokaryotic proteases 11 c3h5cB_ 100.0 18 PDB header:hydrolase inhibitor/blood clotting Chain: B: PDB Molecule:vitamin k-dependent protein z; PDBTitle: x-ray structure of protein z-protein z inhibitor complex 12 c2xrcD_ 100.0 19 PDB header:immune system Chain: D: PDB Molecule:human complement factor i; PDBTitle: human complement factor i 13 c1gpzB_ 100.0 16 PDB header:hydrolase Chain: B: PDB Molecule:complement c1r component; PDBTitle: the crystal structure of the zymogen catalytic domain of2 complement protease c1r 14 c2xxlB_ 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:gram-positive specific serine protease, isoform b; PDBTitle: crystal structure of drosophila grass clip serine protease2 of toll pathway 15 d1a5ia_ 100.0 18 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 16 c1z71A_ 100.0 20 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:thrombin; PDBTitle: thrombin and p2 pyridine n-oxide inhibitor complex structure 17 d1mzaa_ 100.0 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 18 c1md7A_ 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:c1r complement serine protease; PDBTitle: monomeric structure of the zymogen of complement protease2 c1r 19 d1rjxb_ 100.0 21 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 20 c1q3xA_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:mannan-binding lectin serine protease 2; PDBTitle: crystal structure of the catalytic region of human masp-2 21 d1pytd_ not modelled 100.0 20 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 22 c1wczA_ not modelled 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:glutamyl endopeptidase; PDBTitle: crystal structure of an alkaline form of v8 protease from2 staphylococcus aureus 23 c1elvA_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:complement c1s component; PDBTitle: crystal structure of the catalytic domain of human complement c1s2 protease 24 c2w7uC_ not modelled 100.0 16 PDB header:hydrolase Chain: C: PDB Molecule:serine protease spla; PDBTitle: spla serine protease of staphylococcus aureus (2.4a) 25 c2vntE_ not modelled 100.0 20 PDB header:hydrolase Chain: E: PDB Molecule:urokinase-type plasminogen activator; PDBTitle: urokinase-type plasminogen activator inhibitor complex with2 a 1-(7-sulphoamidoisoquinolinyl)guanidine 26 d1z8ga1 not modelled 100.0 19 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 27 c2asuB_ not modelled 100.0 14 PDB header:hydrolase Chain: B: PDB Molecule:hepatocyte growth factor-like protein; PDBTitle: crystal structure of the beta-chain of hgfl/msp 28 d1agja_ not modelled 100.0 23 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Prokaryotic proteases 29 d1rrka1 not modelled 100.0 20 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 30 c1ybwA_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:hepatocyte growth factor activator precursor; PDBTitle: protease domain of hgfa with no inhibitor 31 c2olgA_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:pro-phenoloxidase activating enzyme-i; PDBTitle: crystal structure of the serine protease domain of prophenoloxidase2 activating factor-i in a zymogen form 32 d2o8la1 not modelled 100.0 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Prokaryotic proteases 33 c2o8lA_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:v8 protease; PDBTitle: structure of v8 protease from staphylococcus aureus 34 c1fizA_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:beta-acrosin heavy chain; PDBTitle: three dimensional structure of beta-acrosin from boar2 spermatozoa 35 c1w0zU_ not modelled 100.0 19 PDB header:hydrolase Chain: U: PDB Molecule:urokinase-type plasminogen activator; PDBTitle: urokinase type plasminogen activator 36 c1ghwH_ not modelled 100.0 20 PDB header:hydrolase/hydrolase inhibitor Chain: H: PDB Molecule:thrombin; PDBTitle: a novel serine protease inhibition motif involving a multi-centered2 short hydrogen bonding network at the active site 37 c2vidA_ not modelled 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:serine protease splb; PDBTitle: serine protease splb from staphylococcus aureus at 1.8a2 resolution 38 c1qy6A_ not modelled 100.0 15 PDB header:protease Chain: A: PDB Molecule:serine protease; PDBTitle: structue of v8 protease from staphylococcus aureus 39 d1gvza_ not modelled 100.0 15 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 40 c3cp7B_ not modelled 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:alkaline serine protease al20; PDBTitle: crystal structure of a thermostable serine protease al202 from extremophilic microoganism 41 c2r0lA_ not modelled 100.0 16 PDB header:hydrolase, immune system Chain: A: PDB Molecule:hepatocyte growth factor activator; PDBTitle: short form hgfa with inhibitory fab75 42 c3e16B_ not modelled 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:prostasin; PDBTitle: x-ray structure of human prostasin in complex with benzoxazole warhead2 peptidomimic, lysine in p3 43 d1xx9a_ not modelled 100.0 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 44 c3govB_ not modelled 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:masp-1; PDBTitle: crystal structure of the catalytic region of human masp-1 45 d1npma_ not modelled 100.0 18 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 46 d3rp2a_ not modelled 100.0 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 47 c3h7tB_ not modelled 100.0 13 PDB header:hydrolase Chain: B: PDB Molecule:group 3 allergen smipp-s yvt004a06; PDBTitle: crystal structure of scabies mite inactivated protease paralogue s-d12 (smipp-s-d1) 48 d1gvkb_ not modelled 100.0 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 49 c3s9cA_ not modelled 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:vipera russelli proteinase rvv-v gamma; PDBTitle: russell's viper venom serine proteinase, rvv-v in complex with the2 fragment (residues 1533-1546) of human factor v 50 d2f91a1 not modelled 100.0 19 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 51 d1rfna_ not modelled 100.0 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 52 d1si5h_ not modelled 100.0 14 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 53 c1gl1C_ not modelled 100.0 16 PDB header:hydrolase/inhibitor Chain: C: PDB Molecule:alpha-chymotrypsin; PDBTitle: structure of the complex between bovine alpha-chymotrypsin2 and pmp-c, an inhibitor from the insect locusta migratoria 54 d1elta_ not modelled 100.0 20 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 55 d1eaxa_ not modelled 100.0 19 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 56 d1ekbb_ not modelled 100.0 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 57 c3h7oB_ not modelled 100.0 13 PDB header:hydrolase Chain: B: PDB Molecule:group 3 allergen smipp-s yv6023a04; PDBTitle: crystal structure of scabies mite inactivated protease paralogue s-i12 (smipp-s-i1) 58 d1bioa_ not modelled 99.9 21 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 59 d1t32a1 not modelled 99.9 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 60 d1ao5a_ not modelled 99.9 18 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 61 c2zghA_ not modelled 99.9 19 PDB header:hydrolase Chain: A: PDB Molecule:granzyme m; PDBTitle: crystal structure of active granzyme m bound to its product 62 c1ym0A_ not modelled 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:fibrinotic enzyme component b; PDBTitle: crystal structure of earthworm fibrinolytic enzyme component b: a2 novel, glycosylated two-chained trypsin 63 d2bz6h1 not modelled 99.9 20 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 64 d1ltoa_ not modelled 99.9 19 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 65 d1fi8a_ not modelled 99.9 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 66 c3fzzB_ not modelled 99.9 15 PDB header:hydrolase Chain: B: PDB Molecule:granzyme c; PDBTitle: structure of grc 67 c2aiqA_ not modelled 99.9 19 PDB header:hydrolase Chain: A: PDB Molecule:protein c activator; PDBTitle: crystal structure of benzamidine-inhibited protein c activator from2 the venom of copperhead snake agkistrodon contortrix contortrix 68 d1elva1 not modelled 99.9 15 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 69 d1eufa_ not modelled 99.9 17 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 70 c2zchP_ not modelled 99.9 16 PDB header:immune system Chain: P: PDB Molecule:prostate-specific antigen; PDBTitle: crystal structure of human prostate specific antigen2 complexed with an activating antibody 71 d1iaua_ not modelled 99.9 14 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 72 d1gdna_ not modelled 99.9 20 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 73 d1kigh_ not modelled 99.9 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 74 c1fiwA_ not modelled 99.9 20 PDB header:hydrolase Chain: A: PDB Molecule:beta-acrosin heavy chain; PDBTitle: three-dimensional structure of beta-acrosin from ram spermatozoa 75 d1brup_ not modelled 99.9 14 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 76 d1lo6a_ not modelled 99.9 24 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 77 d2p3ub1 not modelled 99.9 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 78 c2oq5A_ not modelled 99.9 19 PDB header:hydrolase Chain: A: PDB Molecule:transmembrane protease, serine 11e; PDBTitle: crystal structure of desc1, a new member of the type ii2 transmembrane serine proteinases family 79 d1fxya_ not modelled 99.9 18 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 80 d2fpza1 not modelled 99.9 20 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 81 c2qxhA_ not modelled 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:kallikrein-7; PDBTitle: crystal structure of human kallikrein 7 in complex with suc-2 ala-ala-pro-phe-chloromethylketone 82 d1autc_ not modelled 99.9 21 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 83 d1m9ua_ not modelled 99.9 19 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 84 d1os8a_ not modelled 99.9 19 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Prokaryotic proteases 85 d1op0a_ not modelled 99.9 19 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 86 d1sgfg_ not modelled 99.9 18 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 87 d1qtfa_ not modelled 99.9 19 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Prokaryotic proteases 88 c2anyA_ not modelled 99.9 16 PDB header:blood clotting, hydrolase Chain: A: PDB Molecule:plasma kallikrein, light chain; PDBTitle: expression, crystallization and the three-dimensional2 structure of the catalytic domain of human plasma3 kallikrein: implications for structure-based design of4 protease inhibitors 89 c2bdiO_ not modelled 99.9 16 PDB header:hydrolase Chain: O: PDB Molecule:kallikrein-4; PDBTitle: human kallikrein 4 complex with cobalt and p-2 aminobenzamidine 90 d1arba_ not modelled 99.9 22 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Prokaryotic proteases 91 d1sgfa_ not modelled 99.9 18 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 92 d1v2lt_ not modelled 99.9 15 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 93 d1trna_ not modelled 99.9 18 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 94 c1spjA_ not modelled 99.9 18 PDB header:hydrolase Chain: A: PDB Molecule:kallikrein 1; PDBTitle: structure of mature human tissue kallikrein (human kallikrein 1 or2 klk1) at 1.70 angstrom resolution with vacant active site 95 d1eq9a_ not modelled 99.9 20 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 96 d1pfxc_ not modelled 99.9 15 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 97 d1a7sa_ not modelled 99.9 21 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 98 d1fuja_ not modelled 99.9 19 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 99 d1nn6a_ not modelled 99.9 18 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 100 d1tona_ not modelled 99.9 17 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 101 d2hlca_ not modelled 99.9 19 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 102 d1dpoa_ not modelled 99.9 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 103 d1hj9a_ not modelled 99.9 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 104 d1q3xa1 not modelled 99.9 19 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 105 d1hj8a_ not modelled 99.9 12 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 106 d1a0ja_ not modelled 99.9 17 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 107 d2qy0b1 not modelled 99.9 16 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 108 d1h4wa_ not modelled 99.9 18 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 109 d1orfa_ not modelled 99.9 18 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 110 c2as9B_ not modelled 99.9 15 PDB header:hydrolase Chain: B: PDB Molecule:serine protease; PDBTitle: functional and structural characterization of spl proteases2 from staphylococcus aureus 111 d2a31a1 not modelled 99.9 18 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 112 c2psxA_ not modelled 99.9 18 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:kallikrein-5; PDBTitle: crystal structure of human kallikrein 5 in complex with leupeptin 113 d1pytc_ not modelled 99.9 17 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 114 c1bhxB_ not modelled 99.9 22 PDB header:serine protease Chain: B: PDB Molecule:alpha thrombin; PDBTitle: x-ray structure of the complex of human alpha thrombin with the2 inhibitor sdz 229-357 115 d1bqya_ not modelled 99.9 22 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 116 d1azza_ not modelled 99.9 17 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 117 d2z7fe1 not modelled 99.9 19 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 118 c1uhbA_ not modelled 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:trypsin; PDBTitle: crystal structure of porcine alpha trypsin bound with auto2 catalyticaly produced native peptide at 2.15 a resolution 119 d1fona_ not modelled 99.9 18 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Eukaryotic proteases 120 c2ea3A_ not modelled 99.8 16 PDB header:hydrolase Chain: A: PDB Molecule:chymotrypsin; PDBTitle: crystal structure of cellulomonas bogoriensis chymotrypsin