Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	G	N	N	L	L	S	A	K	A	T	L	P	V	Y	D	L	N	N	L	A	P	R	I	V	H	L	G	F	G	A	F	H	R	A	H	Q	G	V	Y	A	D	I	L	A	T	E	H	F	S	D	W	G	Y	Y	E	V	N	L	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?		?																																							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	G	E	Q	Q	I	A	D	L	Q	Q	Q	D	N	L	Y	T	V	A	E	M	S	A	D	V	W	T	A	R	V	V	G	V	V	K	K	A	L	H	V	Q	I	D	G	L	E	T	V	L	A	A	M	C	E	P	Q	I	A	I	V
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	L	T	I	T	E	K	G	Y	F	H	S	P	A	T	G	Q	L	M	L	D	H	P	M	V	A	A	D	V	Q	N	P	H	Q	P	K	T	A	T	G	V	I	V	E	A	L	A	R	R	K	A	A	G	L	P	A	F	T	V	M
Secondary structure
SS confidence
Disorder																															?					?																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	C	D	N	M	P	E	N	G	H	V	M	R	D	V	V	T	S	Y	A	Q	A	V	D	V	K	L	A	Q	W	I	E	D	N	V	T	F	P	S	T	M	V	D	R	I	V	P	A	V	T	E	D	T	L	A	K	I	E	Q	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	G	V	R	D	P	A	G	V	A	C	E	P	F	R	Q	W	V	I	E	D	N	F	V	A	G	R	P	E	W	E	K	A	G	A	E	L	V	S	D	V	L	P	Y	E	E	M	K	L	R	M	L	N	G	S	H	S	F	L	A
Secondary structure
SS confidence
Disorder																									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		Y	L	G	Y	L	A	G	Y	Q	H	I	N	D	C	M	E	D	E	H	Y	R	Y	A	A	Y	G	L	M	L	Q	E	Q	A	P	T	L	K	V	Q	G	V	D	L	Q	D	Y	A	N	R	L	I	A	R	Y	S	N	P	A	L	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		H	R	T	W	Q	I	A	M	D	G	S	Q	K	L	P	Q	R	M	L	D	S	V	R	W	H	L	A	H	D	S	K	F	D	L	L	A	L	G	V	A	G	W	M	R	Y	V	G	G	V	D	E	Q	G	N	P	I	E	I	S	D
Secondary structure
SS confidence
Disorder							?		?	?					?																																							?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		P	L	L	P	V	I	Q	K	A	V	Q	S	S	A	E	G	K	A	R	V	Q	S	L	L	A	I	K	A	I	F	G	D	D	L	P	D	N	S	L	F	T	A	R	V	T	E	T	Y	L	S	L	L	A	H	G	A	K	A	T	V
Secondary structure
SS confidence
Disorder															?	?
Disorder confidence
		.	.	.	.	.	.
Sequence		A	K	Y	S	V	K
Secondary structure
SS confidence
Disorder					?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1m2w chain A Region: 1 - 483 Aligned: 479 Modelled: 483 Confidence: 100.0% Identity: 38% PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol dehydrogenase; PDBTitle: pseudomonas fluorescens mannitol 2-dehydrogenase ternary complex with2 nad and d-mannitol Phyre2 PDB 3h2z chain A Region: 23 - 472 Aligned: 369 Modelled: 403 Confidence: 100.0% Identity: 25% PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol-1-phosphate 5-dehydrogenase; PDBTitle: the crystal structure of mannitol-1-phosphate dehydrogenase from2 shigella flexneri Phyre2 PDB 1lj8 chain A domain 4 Region: 4 - 279 Aligned: 275 Modelled: 276 Confidence: 100.0% Identity: 39% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain Phyre2 PDB 1lj8 chain A domain 3 Region: 280 - 483 Aligned: 201 Modelled: 204 Confidence: 100.0% Identity: 36% Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like Family: Mannitol 2-dehydrogenase Phyre2 PDB 2axq chain A Region: 23 - 125 Aligned: 73 Modelled: 79 Confidence: 53.5% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine dehydrogenase; PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae Phyre2 PDB 3mtj chain A Region: 21 - 123 Aligned: 98 Modelled: 103 Confidence: 44.1% Identity: 11% PDB header:oxidoreductase Chain: A: PDB Molecule:homoserine dehydrogenase; PDBTitle: the crystal structure of a homoserine dehydrogenase from thiobacillus2 denitrificans to 2.15a Phyre2 PDB 1k4i chain A Region: 164 - 214 Aligned: 50 Modelled: 51 Confidence: 43.7% Identity: 12% Fold: YrdC/RibB Superfamily: YrdC/RibB Family: 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB Phyre2 PDB 2ph5 chain A Region: 20 - 204 Aligned: 144 Modelled: 152 Confidence: 39.5% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:homospermidine synthase; PDBTitle: crystal structure of the homospermidine synthase hss from legionella2 pneumophila in complex with nad, northeast structural genomics target3 lgr54 Phyre2 PDB 1gzs chain B Region: 319 - 362 Aligned: 44 Modelled: 44 Confidence: 37.8% Identity: 11% Fold: SopE-like GEF domain Superfamily: SopE-like GEF domain Family: SopE-like GEF domain Phyre2 PDB 3e59 chain A Region: 282 - 381 Aligned: 75 Modelled: 80 Confidence: 35.8% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:pyoverdine biosynthesis protein pvca; PDBTitle: crystal structure of the pvca (pa2254) protein from pseudomonas2 aeruginosa Phyre2 PDB 1snn chain A Region: 164 - 210 Aligned: 46 Modelled: 47 Confidence: 34.7% Identity: 22% Fold: YrdC/RibB Superfamily: YrdC/RibB Family: 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB Phyre2 PDB 3euw chain B Region: 20 - 196 Aligned: 134 Modelled: 148 Confidence: 32.9% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:myo-inositol dehydrogenase; PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032 Phyre2 PDB 1qus chain A Region: 316 - 468 Aligned: 118 Modelled: 136 Confidence: 32.7% Identity: 12% Fold: Lysozyme-like Superfamily: Lysozyme-like Family: Bacterial muramidase, catalytic domain Phyre2 PDB 3mio chain A Region: 164 - 214 Aligned: 50 Modelled: 51 Confidence: 32.5% Identity: 20% PDB header:lyase Chain: A: PDB Molecule:3,4-dihydroxy-2-butanone 4-phosphate synthase; PDBTitle: crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase2 domain from mycobacterium tuberculosis at ph 6.00 Phyre2 PDB 3fgg chain A Region: 301 - 354 Aligned: 54 Modelled: 54 Confidence: 28.4% Identity: 13% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein bce2196; PDBTitle: crystal structure of putative ecf-type sigma factor negative effector2 from bacillus cereus Phyre2 PDB 1r0k chain A domain 2 Region: 21 - 131 Aligned: 104 Modelled: 111 Confidence: 27.6% Identity: 11% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 3ego chain B Region: 275 - 401 Aligned: 120 Modelled: 127 Confidence: 26.7% Identity: 10% PDB header:oxidoreductase Chain: B: PDB Molecule:probable 2-dehydropantoate 2-reductase; PDBTitle: crystal structure of probable 2-dehydropantoate 2-reductase2 pane from bacillus subtilis Phyre2 PDB 3nt5 chain B Region: 20 - 75 Aligned: 50 Modelled: 56 Confidence: 23.2% Identity: 22% PDB header:oxidoreductase Chain: B: PDB Molecule:inositol 2-dehydrogenase/d-chiro-inositol 3-dehydrogenase; PDBTitle: crystal structure of myo-inositol dehydrogenase from bacillus subtilis2 with bound cofactor and product inosose Phyre2 PDB 1r0l chain D Region: 21 - 261 Aligned: 180 Modelled: 187 Confidence: 21.7% Identity: 13% PDB header:oxidoreductase Chain: D: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase; PDBTitle: 1-deoxy-d-xylulose 5-phosphate reductoisomerase from2 zymomonas mobilis in complex with nadph Phyre2 PDB 2o8r chain A domain 3 Region: 23 - 33 Aligned: 11 Modelled: 11 Confidence: 21.5% Identity: 36% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Polyphosphate kinase C-terminal domain Phyre2 1 c1m2wA_ 2 c3h2zA_ 3 d1lj8a4 4 d1lj8a3 5 c2axqA_ 6 c3mtjA_ 7 d1k4ia_ 8 c2ph5A_ 9 d1gzsb_ 10 c3e59A_ 11 d1snna_ 12 c3euwB_ 13 d1qusa_ 14 c3mioA_ 15 c3fggA_ 16 d1r0ka2 17 c3egoB_ 18 c3nt5B_ 19 c1r0lD_ 20 d2o8ra3 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1m2wA_ 100.0 38 PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol dehydrogenase; PDBTitle: pseudomonas fluorescens mannitol 2-dehydrogenase ternary complex with2 nad and d-mannitol 2 c3h2zA_ 100.0 25 PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol-1-phosphate 5-dehydrogenase; PDBTitle: the crystal structure of mannitol-1-phosphate dehydrogenase from2 shigella flexneri 3 d1lj8a4 100.0 39 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 4 d1lj8a3 100.0 36 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like Family:Mannitol 2-dehydrogenase 5 c2axqA_ 53.5 15 PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine dehydrogenase; PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae 6 c3mtjA_ 44.1 11 PDB header:oxidoreductase Chain: A: PDB Molecule:homoserine dehydrogenase; PDBTitle: the crystal structure of a homoserine dehydrogenase from thiobacillus2 denitrificans to 2.15a 7 d1k4ia_ 43.7 12 Fold:YrdC/RibB Superfamily:YrdC/RibB Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB 8 c2ph5A_ 39.5 17 PDB header:transferase Chain: A: PDB Molecule:homospermidine synthase; PDBTitle: crystal structure of the homospermidine synthase hss from legionella2 pneumophila in complex with nad, northeast structural genomics target3 lgr54 9 d1gzsb_ 37.8 11 Fold:SopE-like GEF domain Superfamily:SopE-like GEF domain Family:SopE-like GEF domain 10 c3e59A_ 35.8 16 PDB header:transferase Chain: A: PDB Molecule:pyoverdine biosynthesis protein pvca; PDBTitle: crystal structure of the pvca (pa2254) protein from pseudomonas2 aeruginosa 11 d1snna_ 34.7 22 Fold:YrdC/RibB Superfamily:YrdC/RibB Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB 12 c3euwB_ 32.9 19 PDB header:oxidoreductase Chain: B: PDB Molecule:myo-inositol dehydrogenase; PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032 13 d1qusa_ 32.7 12 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:Bacterial muramidase, catalytic domain 14 c3mioA_ 32.5 20 PDB header:lyase Chain: A: PDB Molecule:3,4-dihydroxy-2-butanone 4-phosphate synthase; PDBTitle: crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase2 domain from mycobacterium tuberculosis at ph 6.00 15 c3fggA_ 28.4 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein bce2196; PDBTitle: crystal structure of putative ecf-type sigma factor negative effector2 from bacillus cereus 16 d1r0ka2 27.6 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 17 c3egoB_ 26.7 10 PDB header:oxidoreductase Chain: B: PDB Molecule:probable 2-dehydropantoate 2-reductase; PDBTitle: crystal structure of probable 2-dehydropantoate 2-reductase2 pane from bacillus subtilis 18 c3nt5B_ 23.2 22 PDB header:oxidoreductase Chain: B: PDB Molecule:inositol 2-dehydrogenase/d-chiro-inositol 3-dehydrogenase; PDBTitle: crystal structure of myo-inositol dehydrogenase from bacillus subtilis2 with bound cofactor and product inosose 19 c1r0lD_ 21.7 13 PDB header:oxidoreductase Chain: D: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase; PDBTitle: 1-deoxy-d-xylulose 5-phosphate reductoisomerase from2 zymomonas mobilis in complex with nadph 20 d2o8ra3 21.5 36 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 21 c1z9bA_ not modelled 21.2 13 PDB header:translation Chain: A: PDB Molecule:translation initiation factor if-2; PDBTitle: solution structure of the c1-subdomain of bacillus2 stearothermophilus translation initiation factor if2 22 c3ceaA_ not modelled 21.0 8 PDB header:oxidoreductase Chain: A: PDB Molecule:myo-inositol 2-dehydrogenase; PDBTitle: crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from2 lactobacillus plantarum at 2.40 a resolution 23 c2qytA_ not modelled 21.0 21 PDB header:oxidoreductase Chain: A: PDB Molecule:2-dehydropantoate 2-reductase; PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from porphyromonas2 gingivalis w83 24 c1e5lA_ not modelled 21.0 16 PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine reductase; PDBTitle: apo saccharopine reductase from magnaporthe grisea 25 c1ceuA_ not modelled 19.7 44 PDB header:viral protein Chain: A: PDB Molecule:protein (hiv-1 regulatory protein n-terminal PDBTitle: nmr structure of the (1-51) n-terminal domain of the hiv-12 regulatory protein 26 c2o8rA_ not modelled 18.6 36 PDB header:transferase Chain: A: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of polyphosphate kinase from2 porphyromonas gingivalis 27 d1v8fa_ not modelled 16.7 25 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) 28 c2cu2A_ not modelled 16.6 17 PDB header:transferase Chain: A: PDB Molecule:putative mannose-1-phosphate guanylyl transferase; PDBTitle: crystal structure of mannose-1-phosphate geranyltransferase from2 thermus thermophilus hb8 29 d1ftaa_ not modelled 15.8 25 Fold:Carbohydrate phosphatase Superfamily:Carbohydrate phosphatase Family:Inositol monophosphatase/fructose-1,6-bisphosphatase-like 30 c2q4eB_ not modelled 15.6 16 PDB header:oxidoreductase Chain: B: PDB Molecule:probable oxidoreductase at4g09670; PDBTitle: ensemble refinement of the protein crystal structure of gene product2 from arabidopsis thaliana at4g09670 31 d2py6a1 not modelled 15.0 30 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:FkbM-like 32 c2gq1A_ not modelled 14.8 17 PDB header:hydrolase Chain: A: PDB Molecule:fructose-1,6-bisphosphatase; PDBTitle: crystal structure of recombinant type i fructose-1,6-bisphosphatase2 from escherichia coli complexed with sulfate ions 33 c2fhyL_ not modelled 14.7 25 PDB header:hydrolase Chain: L: PDB Molecule:fructose-1,6-bisphosphatase 1; PDBTitle: structure of human liver fpbase complexed with a novel2 benzoxazole as allosteric inhibitor 34 c3ghyA_ not modelled 14.4 14 PDB header:oxidoreductase Chain: A: PDB Molecule:ketopantoate reductase protein; PDBTitle: crystal structure of a putative ketopantoate reductase from ralstonia2 solanacearum molk2 35 d2v0fa1 not modelled 13.2 40 Fold:GYF/BRK domain-like Superfamily:BRK domain-like Family:BRK domain-like 36 c3dapB_ not modelled 12.9 17 PDB header:oxidoreductase Chain: B: PDB Molecule:diaminopimelic acid dehydrogenase; PDBTitle: c. glutamicum dap dehydrogenase in complex with nadp+ and2 the inhibitor 5s-isoxazoline 37 d1e5qa1 not modelled 12.4 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 38 c3guzB_ not modelled 12.0 21 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: structural and substrate-binding studies of pantothenate2 synthenate (ps)provide insights into homotropic inhibition3 by pantoate in ps's 39 c3hn2A_ not modelled 12.0 13 PDB header:oxidoreductase Chain: A: PDB Molecule:2-dehydropantoate 2-reductase; PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from geobacter2 metallireducens gs-15 40 c3c7cB_ not modelled 11.8 16 PDB header:oxidoreductase Chain: B: PDB Molecule:octopine dehydrogenase; PDBTitle: a structural basis for substrate and stereo selectivity in2 octopine dehydrogenase (odh-nadh-l-arginine) 41 c3omdB_ not modelled 11.6 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of unknown function protein from leptospirillum2 rubarum 42 d1uj8a1 not modelled 11.2 16 Fold:Another 3-helical bundle Superfamily:IscX-like Family:IscX-like 43 c3n8hA_ not modelled 10.6 25 PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine ligase from francisella2 tularensis 44 d2a1jb1 not modelled 10.5 16 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 45 d1r6ea_ not modelled 10.4 14 Fold:SopE-like GEF domain Superfamily:SopE-like GEF domain Family:SopE-like GEF domain 46 c3tbiA_ not modelled 10.4 21 PDB header:transcription Chain: A: PDB Molecule:rna polymerase-associated protein gp33; PDBTitle: crystal structure of t4 gp33 bound to e. coli rnap beta-flap domain 47 c2k0rA_ not modelled 10.1 14 PDB header:oxidoreductase Chain: A: PDB Molecule:thiol:disulfide interchange protein dsbd; PDBTitle: solution structure of the c103s mutant of the n-terminal2 domain of dsbd from neisseria meningitidis 48 d1bk4a_ not modelled 10.0 25 Fold:Carbohydrate phosphatase Superfamily:Carbohydrate phosphatase Family:Inositol monophosphatase/fructose-1,6-bisphosphatase-like 49 c2c9lZ_ not modelled 9.8 40 PDB header:viral protein Chain: Z: PDB Molecule:bzlf1 trans-activator protein; PDBTitle: structure of the epstein-barr virus zebra protein 50 c2ejcA_ not modelled 9.7 18 PDB header:ligase Chain: A: PDB Molecule:pantoate--beta-alanine ligase; PDBTitle: crystal structure of pantoate--beta-alanine ligase (panc)2 from thermotoga maritima 51 d1f06a1 not modelled 9.4 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 52 d2cu2a2 not modelled 9.3 13 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:mannose-1-phosphate guanylyl transferase 53 d1nuwa_ not modelled 9.3 25 Fold:Carbohydrate phosphatase Superfamily:Carbohydrate phosphatase Family:Inositol monophosphatase/fructose-1,6-bisphosphatase-like 54 c3innB_ not modelled 9.2 18 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine-ligase in complex2 with atp at low occupancy at 2.1 a resolution 55 d2oc5a1 not modelled 9.0 24 Fold:Ferritin-like Superfamily:Ferritin-like Family:PMT1231-like 56 c1yy3A_ not modelled 9.0 22 PDB header:isomerase Chain: A: PDB Molecule:s-adenosylmethionine:trna ribosyltransferase- PDBTitle: structure of s-adenosylmethionine:trna ribosyltransferase-2 isomerase (quea) 57 d2ouxa1 not modelled 8.9 10 Fold:alpha-alpha superhelix Superfamily:MgtE N-terminal domain-like Family:MgtE N-terminal domain-like 58 c3ketA_ not modelled 8.8 12 PDB header:transcription/dna Chain: A: PDB Molecule:redox-sensing transcriptional repressor rex; PDBTitle: crystal structure of a rex-family transcriptional regulatory protein2 from streptococcus agalactiae bound to a palindromic operator 59 c3bjrA_ not modelled 8.8 13 PDB header:hydrolase Chain: A: PDB Molecule:putative carboxylesterase; PDBTitle: crystal structure of a putative carboxylesterase (lp_1002) from2 lactobacillus plantarum wcfs1 at 2.09 a resolution 60 c2qpqC_ not modelled 8.7 19 PDB header:transport protein Chain: C: PDB Molecule:protein bug27; PDBTitle: structure of bug27 from bordetella pertussis 61 c1fi0A_ not modelled 8.6 44 PDB header:viral protein Chain: A: PDB Molecule:vpr protein; PDBTitle: solution structure of hiv-1 vpr (13-33) peptide in micells 62 c3g17H_ not modelled 8.6 12 PDB header:structural genomics, unknown function Chain: H: PDB Molecule:similar to 2-dehydropantoate 2-reductase; PDBTitle: structure of putative 2-dehydropantoate 2-reductase from2 staphylococcus aureus 63 c2x41A_ not modelled 8.3 7 PDB header:hydrolase Chain: A: PDB Molecule:beta-glucosidase; PDBTitle: structure of beta-glucosidase 3b from thermotoga neapolitana2 in complex with glucose 64 c2x5sB_ not modelled 8.2 14 PDB header:transferase Chain: B: PDB Molecule:mannose-1-phosphate guanylyltransferase; PDBTitle: crystal structure of t. maritima gdp-mannose2 pyrophosphorylase in apo state. 65 d1g7sa3 not modelled 8.2 16 Fold:Initiation factor IF2/eIF5b, domain 3 Superfamily:Initiation factor IF2/eIF5b, domain 3 Family:Initiation factor IF2/eIF5b, domain 3 66 d1xdpa3 not modelled 8.2 50 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 67 d2dt5a2 not modelled 8.0 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Transcriptional repressor Rex, C-terminal domain 68 c3b20R_ not modelled 7.4 19 PDB header:oxidoreductase Chain: R: PDB Molecule:glyceraldehyde 3-phosphate dehydrogenase (nadp+); PDBTitle: crystal structure analysis of dehydrogenase complexed with nad 69 d1u2ka_ not modelled 7.3 26 Fold:Heme-dependent peroxidases Superfamily:Heme-dependent peroxidases Family:Catalase-peroxidase KatG 70 c2k2iB_ not modelled 7.3 36 PDB header:cell cycle Chain: B: PDB Molecule:sfi1 peptide; PDBTitle: nmr solution structure of the c-terminal domain (t94-y172)2 of the human centrin 2 in complex with a repeat sequence of3 human sfi1 (r641-t660) 71 c3h8gC_ not modelled 7.3 15 PDB header:hydrolase Chain: C: PDB Molecule:cytosol aminopeptidase; PDBTitle: bestatin complex structure of leucine aminopeptidase from pseudomonas2 putida 72 d1ihoa_ not modelled 7.2 21 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) 73 c3rrlC_ not modelled 7.2 18 PDB header:transferase Chain: C: PDB Molecule:succinyl-coa:3-ketoacid-coenzyme a transferase subunit a; PDBTitle: complex structure of 3-oxoadipate coa-transferase subunit a and b from2 helicobacter pylori 26695 74 c1txgA_ not modelled 7.2 14 PDB header:oxidoreductase Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+]; PDBTitle: structure of glycerol-3-phosphate dehydrogenase from archaeoglobus2 fulgidus 75 d1o7fa1 not modelled 7.0 17 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:DEP domain 76 c3r24A_ not modelled 7.0 50 PDB header:transferase, viral protein Chain: A: PDB Molecule:2'-o-methyl transferase; PDBTitle: crystal structure of nsp10/nsp16 complex of sars coronavirus" if2 possible 77 c1u2jC_ not modelled 6.9 26 PDB header:oxidoreductase Chain: C: PDB Molecule:peroxidase/catalase hpi; PDBTitle: crystal structure of the c-terminal domain from the2 catalase-peroxidase katg of escherichia coli (p21 21 21) 78 d1t0la_ not modelled 6.9 11 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 79 c3ogiC_ not modelled 6.8 20 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:putative esat-6-like protein 6; PDBTitle: crystal structure of the mycobacterium tuberculosis h37rv esxop2 complex (rv2346c-rv2347c) 80 c2d2iO_ not modelled 6.7 19 PDB header:oxidoreductase Chain: O: PDB Molecule:glyceraldehyde 3-phosphate dehydrogenase; PDBTitle: crystal structure of nadp-dependent glyceraldehyde-3-2 phosphate dehydrogenase from synechococcus sp. complexed3 with nadp+ 81 d1mrza2 not modelled 6.7 24 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 82 c3tevA_ not modelled 6.6 10 PDB header:hydrolase Chain: A: PDB Molecule:glycosyl hyrolase, family 3; PDBTitle: the crystal structure of glycosyl hydrolase from deinococcus2 radiodurans r1 83 d1m9dc_ not modelled 6.6 15 Fold:Retrovirus capsid protein, N-terminal core domain Superfamily:Retrovirus capsid protein, N-terminal core domain Family:Retrovirus capsid protein, N-terminal core domain 84 c3fk4A_ not modelled 6.3 16 PDB header:isomerase Chain: A: PDB Molecule:rubisco-like protein; PDBTitle: crystal structure of rubisco-like protein from bacillus2 cereus atcc 14579 85 c2xvtC_ not modelled 6.2 33 PDB header:membrane protein Chain: C: PDB Molecule:receptor activity-modifying protein 2; PDBTitle: structure of the extracellular domain of human ramp2 86 c3ag5A_ not modelled 6.2 21 PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantothenate synthetase from staphylococcus2 aureus 87 d1veha_ not modelled 6.1 25 Fold:Alpha-lytic protease prodomain-like Superfamily:Fe-S cluster assembly (FSCA) domain-like Family:NifU C-terminal domain-like 88 d2hiqa1 not modelled 6.0 16 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Hypothetical protein YdhR 89 c3q2kB_ not modelled 5.9 15 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of the wlba dehydrogenase from bordetella pertussis2 in complex with nadh and udp-glcnaca 90 c2o8sA_ not modelled 5.9 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:agr_c_984p; PDBTitle: x-ray crystal structure of protein agr_c_984 from agrobacterium2 tumefaciens. northeast structural genomics consortium target atr120. 91 d1f0xa1 not modelled 5.8 38 Fold:Ferredoxin-like Superfamily:FAD-linked oxidases, C-terminal domain Family:D-lactate dehydrogenase 92 c2k8sA_ not modelled 5.7 46 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: solution nmr structure of dimeric thioredoxin-like protein2 ne0084 from nitrosomonas europea: northeast structural3 genomics target net6 93 c2ew2B_ not modelled 5.6 12 PDB header:oxidoreductase Chain: B: PDB Molecule:2-dehydropantoate 2-reductase, putative; PDBTitle: crystal structure of the putative 2-dehydropantoate 2-reductase from2 enterococcus faecalis 94 d2pg4a1 not modelled 5.6 15 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:F93-like 95 c3f3mA_ not modelled 5.5 12 PDB header:transferase Chain: A: PDB Molecule:phosphopantetheine adenylyltransferase; PDBTitle: six crystal structures of two phosphopantetheine2 adenylyltransferases reveal an alternative ligand binding3 mode and an associated structural change 96 c1lanA_ not modelled 5.5 13 PDB header:hydrolase (alpha-aminoacylpeptide) Chain: A: PDB Molecule:leucine aminopeptidase; PDBTitle: leucine aminopeptidase complex with l-leucinal 97 d1vm6a3 not modelled 5.5 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 98 d2ahua2 not modelled 5.5 13 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:CoA transferase alpha subunit-like 99 d1hcia1 not modelled 5.4 26 Fold:Spectrin repeat-like Superfamily:Spectrin repeat Family:Spectrin repeat

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0