Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	L	F	A	D	Y	N	T	P	Y	L	F	A	I	S	F	V	L	L	I	G	L	L	E	I	F	A	L	I	C	G	H	M	L	S	G	A	L	D	A	H	L	D	H	Y	D	S	I	T	T	G	H	I	S	Q	A	L	H	Y
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																?	?	?	?				?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	N	I	G	R	L	P	A	L	V	V	L	C	L	L	A	G	F	F	G	L	I	G	I	L	L	Q	H	A	C	I	M	V	W	Q	S	P	L	S	N	L	F	V	V	P	V	S	L	L	F	T	I	I	A	V	H	Y	T	G	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	V	A	P	W	I	P	R	D	H	S	S	A	I	T	E	E	E	Y	I	G	S	M	A	L	I	T	G	H	Q	A	T	S	G	N	P	C	E	G	K	L	T	D	Q	F	G	Q	I	H	Y	L	L	L	E	P	E	E	G	K	I
Secondary structure
SS confidence
Disorder															?	?	?													?	?	?	?	?	?		?																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.
Sequence		F	T	K	G	D	K	V	L	I	I	C	R	L	S	A	T	R	Y	L	A	E	N	N	P	W	P	Q	I	L
Secondary structure
SS confidence
Disorder																								?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2k14 chain A Region: 129 - 204 Aligned: 74 Modelled: 76 Confidence: 98.7% Identity: 14% PDB header:unknown function Chain: A: PDB Molecule:yuaf protein; PDBTitle: solution structure of the soluble domain of the nfed2 protein yuaf from bacillus subtilis Phyre2 PDB 3cp0 chain A Region: 135 - 201 Aligned: 60 Modelled: 67 Confidence: 97.6% Identity: 15% PDB header:membrane protein Chain: A: PDB Molecule:membrane protein implicated in regulation of membrane PDBTitle: crystal structure of the soluble domain of membrane protein implicated2 in regulation of membrane protease activity from corynebacterium3 glutamicum Phyre2 PDB 2k5h chain A Region: 120 - 203 Aligned: 76 Modelled: 82 Confidence: 97.6% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved protein; PDBTitle: solution nmr structure of protein encoded by mth693 from2 methanobacterium thermoautotrophicum: northeast structural3 genomics consortium target tt824a Phyre2 PDB 2exd chain A domain 1 Region: 128 - 204 Aligned: 67 Modelled: 77 Confidence: 96.5% Identity: 15% Fold: OB-fold Superfamily: NfeD domain-like Family: NfeD domain-like Phyre2 PDB 1l2f chain A Region: 137 - 209 Aligned: 72 Modelled: 73 Confidence: 69.4% Identity: 15% PDB header:transcription Chain: A: PDB Molecule:n utilization substance protein a; PDBTitle: crystal structure of nusa from thermotoga maritima: a2 structure-based role of the n-terminal domain Phyre2 PDB 2ebp chain A Region: 152 - 203 Aligned: 48 Modelled: 52 Confidence: 69.3% Identity: 19% PDB header:cell adhesion Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1; PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1 Phyre2 PDB 2d8j chain A Region: 172 - 206 Aligned: 35 Modelled: 35 Confidence: 61.5% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:fyn-related kinase; PDBTitle: solution structure of the sh3 domain of fyn-related kinase Phyre2 PDB 1wfw chain A Region: 172 - 202 Aligned: 31 Modelled: 31 Confidence: 60.9% Identity: 13% Fold: SH3-like barrel Superfamily: SH3-domain Family: SH3-domain Phyre2 PDB 1hh2 chain P Region: 137 - 209 Aligned: 72 Modelled: 73 Confidence: 59.6% Identity: 15% PDB header:transcription regulation Chain: P: PDB Molecule:n utilization substance protein a; PDBTitle: crystal structure of nusa from thermotoga maritima Phyre2 PDB 2ekh chain A Region: 172 - 203 Aligned: 32 Modelled: 32 Confidence: 58.7% Identity: 9% PDB header:signaling protein Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a; PDBTitle: solution structures of the sh3 domain of human kiaa0418 Phyre2 PDB 1wlp chain B domain 1 Region: 173 - 203 Aligned: 31 Modelled: 31 Confidence: 57.2% Identity: 13% Fold: SH3-like barrel Superfamily: SH3-domain Family: SH3-domain Phyre2 PDB 3dcl chain C Region: 128 - 209 Aligned: 81 Modelled: 82 Confidence: 56.7% Identity: 16% PDB header:structural genomics, unknown function Chain: C: PDB Molecule:tm1086; PDBTitle: crystal structure of tm1086 Phyre2 PDB 1e6h chain A Region: 163 - 203 Aligned: 41 Modelled: 41 Confidence: 51.9% Identity: 22% Fold: SH3-like barrel Superfamily: SH3-domain Family: SH3-domain Phyre2 PDB 2dmo chain A Region: 172 - 203 Aligned: 32 Modelled: 32 Confidence: 51.5% Identity: 16% PDB header:signaling protein Chain: A: PDB Molecule:neutrophil cytosol factor 2; PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2) Phyre2 PDB 1x2p chain A Region: 172 - 203 Aligned: 32 Modelled: 32 Confidence: 50.9% Identity: 25% PDB header:transferase Chain: A: PDB Molecule:protein arginine n-methyltransferase 2; PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2 Phyre2 PDB 1uti chain A Region: 173 - 203 Aligned: 31 Modelled: 31 Confidence: 49.5% Identity: 13% Fold: SH3-like barrel Superfamily: SH3-domain Family: SH3-domain Phyre2 PDB 2djq chain A Region: 173 - 203 Aligned: 31 Modelled: 31 Confidence: 47.8% Identity: 29% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sh3 domain containing ring finger 2; PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2 Phyre2 PDB 1gri chain A Region: 172 - 203 Aligned: 32 Modelled: 32 Confidence: 47.6% Identity: 9% PDB header:signal transduction adaptor Chain: A: PDB Molecule:growth factor bound protein 2; PDBTitle: grb2 Phyre2 PDB 2fo0 chain A domain 1 Region: 172 - 203 Aligned: 32 Modelled: 32 Confidence: 47.5% Identity: 13% Fold: SH3-like barrel Superfamily: SH3-domain Family: SH3-domain Phyre2 PDB 2xmf chain A Region: 172 - 203 Aligned: 32 Modelled: 32 Confidence: 46.3% Identity: 13% PDB header:motor protein Chain: A: PDB Molecule:myosin 1e sh3; PDBTitle: myosin 1e sh3 Phyre2 1 c2k14A_ 2 c3cp0A_ 3 c2k5hA_ 4 d2exda1 5 c1l2fA_ 6 c2ebpA_ 7 c2d8jA_ 8 d1wfwa_ 9 c1hh2P_ 10 c2ekhA_ 11 d1wlpb1 12 c3dclC_ 13 d1e6ha_ 14 c2dmoA_ 15 c1x2pA_ 16 d1utia_ 17 c2djqA_ 18 c1griA_ 19 d2fo0a1 20 c2xmfA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2k14A_ 98.7 14 PDB header:unknown function Chain: A: PDB Molecule:yuaf protein; PDBTitle: solution structure of the soluble domain of the nfed2 protein yuaf from bacillus subtilis 2 c3cp0A_ 97.6 15 PDB header:membrane protein Chain: A: PDB Molecule:membrane protein implicated in regulation of membrane PDBTitle: crystal structure of the soluble domain of membrane protein implicated2 in regulation of membrane protease activity from corynebacterium3 glutamicum 3 c2k5hA_ 97.6 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved protein; PDBTitle: solution nmr structure of protein encoded by mth693 from2 methanobacterium thermoautotrophicum: northeast structural3 genomics consortium target tt824a 4 d2exda1 96.5 15 Fold:OB-fold Superfamily:NfeD domain-like Family:NfeD domain-like 5 c1l2fA_ 69.4 15 PDB header:transcription Chain: A: PDB Molecule:n utilization substance protein a; PDBTitle: crystal structure of nusa from thermotoga maritima: a2 structure-based role of the n-terminal domain 6 c2ebpA_ 69.3 19 PDB header:cell adhesion Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1; PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1 7 c2d8jA_ 61.5 20 PDB header:transferase Chain: A: PDB Molecule:fyn-related kinase; PDBTitle: solution structure of the sh3 domain of fyn-related kinase 8 d1wfwa_ 60.9 13 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 9 c1hh2P_ 59.6 15 PDB header:transcription regulation Chain: P: PDB Molecule:n utilization substance protein a; PDBTitle: crystal structure of nusa from thermotoga maritima 10 c2ekhA_ 58.7 9 PDB header:signaling protein Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a; PDBTitle: solution structures of the sh3 domain of human kiaa0418 11 d1wlpb1 57.2 13 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 12 c3dclC_ 56.7 16 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:tm1086; PDBTitle: crystal structure of tm1086 13 d1e6ha_ 51.9 22 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 14 c2dmoA_ 51.5 16 PDB header:signaling protein Chain: A: PDB Molecule:neutrophil cytosol factor 2; PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2) 15 c1x2pA_ 50.9 25 PDB header:transferase Chain: A: PDB Molecule:protein arginine n-methyltransferase 2; PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2 16 d1utia_ 49.5 13 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 17 c2djqA_ 47.8 29 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sh3 domain containing ring finger 2; PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2 18 c1griA_ 47.6 9 PDB header:signal transduction adaptor Chain: A: PDB Molecule:growth factor bound protein 2; PDBTitle: grb2 19 d2fo0a1 47.5 13 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 20 c2xmfA_ 46.3 13 PDB header:motor protein Chain: A: PDB Molecule:myosin 1e sh3; PDBTitle: myosin 1e sh3 21 d1u06a1 not modelled 45.7 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 22 d1k4us_ not modelled 45.3 19 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 23 c3nmzD_ not modelled 44.2 9 PDB header:cell adhesion/cell cycle Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crytal structure of apc complexed with asef 24 d1efna_ not modelled 43.9 23 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 25 c2drmB_ not modelled 43.4 19 PDB header:contractile protein Chain: B: PDB Molecule:acanthamoeba myosin ib; PDBTitle: acanthamoeba myosin i sh3 domain bound to acan125 26 c2egcA_ not modelled 42.9 17 PDB header:signaling protein Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a; PDBTitle: solution structure of the fifth sh3 domain from human2 kiaa0418 protein 27 c2dl4A_ not modelled 42.7 9 PDB header:signaling protein Chain: A: PDB Molecule:protein stac; PDBTitle: solution structure of the first sh3 domain of stac protein 28 c2cubA_ not modelled 42.5 25 PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1 29 d1opka1 not modelled 42.5 13 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 30 c2ysqA_ not modelled 42.3 9 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9; PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9 31 d1jo8a_ not modelled 41.1 19 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 32 c1x69A_ not modelled 40.5 9 PDB header:signaling protein Chain: A: PDB Molecule:cortactin isoform a; PDBTitle: solution structures of the sh3 domain of human src2 substrate cortactin 33 c2ed0A_ not modelled 40.5 19 PDB header:signaling protein Chain: A: PDB Molecule:abl interactor 2; PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2) 34 d1oeba_ not modelled 40.3 13 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 35 c2kymA_ not modelled 40.3 13 PDB header:signaling protein Chain: A: PDB Molecule:bud emergence protein 1; PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide 36 c2ct4A_ not modelled 40.0 6 PDB header:signaling protein Chain: A: PDB Molecule:cdc42-interacting protein 4; PDBTitle: solution strutcure of the sh3 domain of the cdc42-2 interacting protein 4 37 d1hh2p1 not modelled 39.8 15 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 38 c2dl8A_ not modelled 39.7 23 PDB header:signaling protein Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2; PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2 39 c3m3hA_ not modelled 39.2 18 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.75 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase from bacillus anthracis str. 'ames3 ancestor' 40 c2jmcA_ not modelled 39.1 16 PDB header:signaling protein Chain: A: PDB Molecule:spectrin alpha chain, brain and p41 peptide PDBTitle: chimer between spc-sh3 and p41 41 d1ov3a1 not modelled 38.6 9 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 42 d1ujya_ not modelled 38.3 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 43 c1x2qA_ not modelled 38.1 16 PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 2; PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2 44 d2pyta1 not modelled 37.4 17 Fold:Double-stranded beta-helix Superfamily:RmlC-like cupins Family:EutQ-like 45 c2epdA_ not modelled 37.3 22 PDB header:protein binding Chain: A: PDB Molecule:rho gtpase-activating protein 4; PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4 46 d1ov3a2 not modelled 37.2 13 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 47 c2yuoA_ not modelled 37.0 23 PDB header:signaling protein Chain: A: PDB Molecule:run and tbc1 domain containing 3; PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3 48 c2dbmA_ not modelled 36.9 19 PDB header:transferase, signaling protein Chain: A: PDB Molecule:sh3-containing grb2-like protein 2; PDBTitle: solution structures of the sh3 domain of human sh3-2 containing grb2-like protein 2 49 d1ue9a_ not modelled 36.8 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 50 c2yunA_ not modelled 36.5 19 PDB header:protein transport Chain: A: PDB Molecule:nostrin; PDBTitle: solution structure of the sh3 domain of human nostrin 51 d1h8ka_ not modelled 36.3 13 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 52 c2ed1A_ not modelled 36.3 8 PDB header:signaling protein Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate- PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein 53 c2ct3A_ not modelled 36.2 13 PDB header:signaling protein Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the sh3 domain of the vinexin protein 54 c1u3oA_ not modelled 36.0 19 PDB header:signaling protein Chain: A: PDB Molecule:huntingtin-associated protein-interacting PDBTitle: solution structure of rat kalirin n-terminal sh3 domain 55 c2dnuA_ not modelled 36.0 16 PDB header:structural genomics, structural protein Chain: A: PDB Molecule:sh3 multiple domains 1; PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human 56 c3zvkG_ not modelled 35.8 19 PDB header:antitoxin/toxin/dna Chain: G: PDB Molecule:antitoxin of toxin-antitoxin system vapb; PDBTitle: crystal structure of vapbc2 from rickettsia felis bound to2 a dna fragment from their promoter 57 c2fpeB_ not modelled 35.5 19 PDB header:signaling protein Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein PDBTitle: conserved dimerization of the ib1 src-homology 3 domain 58 c1h9sA_ not modelled 35.1 19 PDB header:transcription regulator Chain: A: PDB Molecule:molybdenum transport protein mode; PDBTitle: molybdate bound complex of dimop domain of mode from e.coli 59 d1nega_ not modelled 34.9 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 60 c1negA_ not modelled 34.9 16 PDB header:structural protein Chain: A: PDB Molecule:spectrin alpha chain, brain; PDBTitle: crystal structure analysis of n-and c-terminal labeled sh3-2 domain of alpha-chicken spectrin 61 d1qlya_ not modelled 34.8 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 62 d1gria2 not modelled 34.8 10 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 63 c1x6gA_ not modelled 34.7 23 PDB header:signaling protein Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase; PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase. 64 c2yupA_ not modelled 34.6 19 PDB header:cell adhesion Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the second sh3 domain of human vinexin 65 d1wiea_ not modelled 34.5 18 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 66 d1pwta_ not modelled 34.2 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 67 d1udla_ not modelled 34.1 19 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 68 c2rqrA_ not modelled 34.1 13 PDB header:protein binding Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex 69 d1sema_ not modelled 34.0 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 70 d1ug1a_ not modelled 34.0 17 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 71 c3zv0D_ not modelled 33.9 10 PDB header:cell cycle Chain: D: PDB Molecule:h/aca ribonucleoprotein complex subunit 4; PDBTitle: structure of the shq1p-cbf5p complex 72 d2q07a1 not modelled 33.7 14 Fold:PUA domain-like Superfamily:PUA domain-like Family:PUA domain 73 d1uj0a_ not modelled 33.6 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 74 c1zuyB_ not modelled 33.5 18 PDB header:contractile protein Chain: B: PDB Molecule:myosin-5 isoform; PDBTitle: high-resolution structure of yeast myo5 sh3 domain 75 c1zx6A_ not modelled 33.1 25 PDB header:protein binding Chain: A: PDB Molecule:ypr154wp; PDBTitle: high-resolution crystal structure of yeast pin3 sh3 domain 76 c2dl5A_ not modelled 33.0 6 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:kiaa0769 protein; PDBTitle: solution structure of the first sh3 domain of human2 kiaa0769 protein 77 c1w70A_ not modelled 32.7 13 PDB header:sh3 domain Chain: A: PDB Molecule:neutrophil cytosol factor 4; PDBTitle: sh3 domain of p40phox complexed with c-terminal polyproline2 region of p47phox 78 d1uuea_ not modelled 32.7 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 79 c1zlmA_ not modelled 32.5 13 PDB header:signaling protein Chain: A: PDB Molecule:osteoclast stimulating factor 1; PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor 80 d1e6ga_ not modelled 32.3 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 81 c2pqhA_ not modelled 32.3 16 PDB header:structural protein Chain: A: PDB Molecule:spectrin alpha chain, brain; PDBTitle: structure of sh3 chimera with a type ii ligand linked to the chain c-2 terminal 82 d1ng2a1 not modelled 32.3 9 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 83 d1ng2a2 not modelled 32.1 13 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 84 c2eczA_ not modelled 31.8 13 PDB header:signaling protein Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1; PDBTitle: solution structure of the sh3 domain of sorbin and sh32 domain-containing protein 1 85 c1wxbA_ not modelled 31.7 6 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:epidermal growth factor receptor pathway PDBTitle: solution structure of the sh3 domain from human epidermal2 growth factor receptor pathway substrate 8-like protein 86 d1h9ra2 not modelled 31.5 17 Fold:OB-fold Superfamily:MOP-like Family:BiMOP, duplicated molybdate-binding domain 87 d1gcqa_ not modelled 31.1 10 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 88 c2df6A_ not modelled 30.9 19 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7; PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2 89 c2krnA_ not modelled 30.6 16 PDB header:signaling protein Chain: A: PDB Molecule:cd2-associated protein; PDBTitle: high resolution structure of the second sh3 domain of cd2ap 90 c2l0aA_ not modelled 30.0 9 PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 1; PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e 91 c2js0A_ not modelled 29.9 26 PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: solution structure of second sh3 domain of adaptor nck 92 c1iq8B_ not modelled 29.8 11 PDB header:transferase Chain: B: PDB Molecule:archaeosine trna-guanine transglycosylase; PDBTitle: crystal structure of archaeosine trna-guanine2 transglycosylase from pyrococcus horikoshii 93 d1wlpb2 not modelled 29.8 9 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 94 c1wi7A_ not modelled 29.1 10 PDB header:protein binding Chain: A: PDB Molecule:sh3-domain kinase binding protein 1; PDBTitle: solution structure of the sh3 domain of sh3-domain kinase2 binding protein 1 95 c2bz8B_ not modelled 28.9 10 PDB header:sh3 domain Chain: B: PDB Molecule:sh3-domain kinase binding protein 1; PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide 96 c1yn8E_ not modelled 28.7 27 PDB header:unknown function Chain: E: PDB Molecule:nap1-binding protein 2; PDBTitle: sh3 domain of yeast nbp2 97 c2yt6A_ not modelled 28.6 23 PDB header:cell cycle Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full- PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1 98 d1j6qa_ not modelled 28.4 11 Fold:OB-fold Superfamily:Heme chaperone CcmE Family:Heme chaperone CcmE 99 c1j6qA_ not modelled 28.4 11 PDB header:chaperone Chain: A: PDB Molecule:cytochrome c maturation protein e; PDBTitle: solution structure and characterization of the heme2 chaperone ccme 100 c1z9qA_ not modelled 28.1 13 PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosol factor 4; PDBTitle: solution structure of sh3 domain of p40phox 101 c2eyxA_ not modelled 27.7 14 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: c-terminal sh3 domain of ct10-regulated kinase 102 c1s1nA_ not modelled 27.7 20 PDB header:cell adhesion Chain: A: PDB Molecule:nephrocystin 1; PDBTitle: sh3 domain of human nephrocystin 103 c2kgtA_ not modelled 27.7 13 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase 6; PDBTitle: solution structure of sh3 domain of ptk6 104 c3cqtA_ not modelled 27.5 22 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn; PDBTitle: n53i v55l mutant of fyn sh3 domain 105 d1g2ba_ not modelled 27.5 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 106 c2ckkA_ not modelled 27.0 16 PDB header:nuclear protein Chain: A: PDB Molecule:kin17; PDBTitle: high resolution crystal structure of the human kin172 c-terminal domain containing a kow motif3 kin17. 107 d1ckaa_ not modelled 26.7 28 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 108 c2k6dA_ not modelled 26.6 17 PDB header:sh3 domain/ubiquitin Chain: A: PDB Molecule:sh3 domain-containing kinase-binding protein 1; PDBTitle: cin85 sh3-c domain in complex with ubiquitin 109 c2nwmA_ not modelled 26.3 19 PDB header:cell adhesion Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin 110 c2eqiA_ not modelled 25.7 6 PDB header:immune system, hydrolase Chain: A: PDB Molecule:phospholipase c, gamma 2; PDBTitle: solution structure of the sh3 domain from phospholipase c,2 gamma 2 111 d1fmka1 not modelled 25.5 22 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 112 d1tuca_ not modelled 25.4 18 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 113 c3es4B_ not modelled 25.1 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein duf861 with a rmlc-like cupin fold; PDBTitle: crystal structure of protein of unknown function (duf861) with a rmlc-2 like cupin fold (17741406) from agrobacterium tumefaciens str. c583 (dupont) at 1.64 a resolution 114 c2dilA_ not modelled 24.8 16 PDB header:cell adhesion Chain: A: PDB Molecule:proline-serine-threonine phosphatase-interacting PDBTitle: solution structure of the sh3 domain of the human proline-2 serine-threonine phosphatase-interacting protein 1 115 c2dl3A_ not modelled 24.7 25 PDB header:cell adhesion, signaling protein Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1; PDBTitle: solution structure of the first sh3 domain of human sorbin2 and sh3 domain-containing protein 1 116 d1lcka1 not modelled 24.6 17 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 117 c2k2mA_ not modelled 24.6 3 PDB header:signaling protein Chain: A: PDB Molecule:eps8-like protein 1; PDBTitle: structural basis of pxxdy motif recognition in sh3 binding 118 c2d1xD_ not modelled 24.5 10 PDB header:cell invasion Chain: D: PDB Molecule:cortactin isoform a; PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex 119 d1uffa_ not modelled 24.4 10 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 120 c2x3wD_ not modelled 24.1 10 PDB header:endocytosis Chain: D: PDB Molecule:protein kinase c and casein kinase substrate in neurons PDBTitle: structure of mouse syndapin i (crystal form 2)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0