Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	I	S	E	L	L	Q	Y	C	M	A	K	P	G	A	E	Q	S	V	H	N	D	W	K	A	T	Q	I	K	V	E	D	V	L	F	A	M	V	K	E	V	E	N	R	P	A	V	S	L	K	T	S	P	E	L	A	E	L	L
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.
Sequence		R	Q	Q	H	S	D	V	R	P	S	R	H	L	N	K	A	H	W	S	T	V	Y	L	D	G	S	L	P	D	S	Q	I	Y	Y	L	V	D	A	S	Y	Q	Q	A	V	N	L	L	P	E	E	K	R	K	L	L	V	Q	L
Secondary structure
SS confidence
Disorder																																																										?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2fki chain A domain 1 Region: 1 - 118 Aligned: 118 Modelled: 118 Confidence: 100.0% Identity: 100% Fold: Secretion chaperone-like Superfamily: YjbR-like Family: YjbR-like Phyre2 PDB 2a1v chain A domain 1 Region: 1 - 115 Aligned: 115 Modelled: 115 Confidence: 100.0% Identity: 33% Fold: Secretion chaperone-like Superfamily: YjbR-like Family: YjbR-like Phyre2 PDB 3h9x chain B Region: 2 - 103 Aligned: 101 Modelled: 102 Confidence: 100.0% Identity: 27% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein pspto_3016; PDBTitle: crystal structure of the pspto_3016 protein from2 pseudomonas syringae, northeast structural genomics3 consortium target psr293 Phyre2 PDB 2oc6 chain A domain 1 Region: 3 - 99 Aligned: 90 Modelled: 97 Confidence: 96.9% Identity: 7% Fold: Secretion chaperone-like Superfamily: YdhG-like Family: YdhG-like Phyre2 PDB 2i8d chain A domain 1 Region: 3 - 99 Aligned: 89 Modelled: 97 Confidence: 96.7% Identity: 9% Fold: Secretion chaperone-like Superfamily: YdhG-like Family: YdhG-like Phyre2 PDB 2kl4 chain A Region: 3 - 99 Aligned: 90 Modelled: 95 Confidence: 96.0% Identity: 8% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:bh2032 protein; PDBTitle: nmr structure of the protein nb7804a Phyre2 PDB 2od0 chain A domain 1 Region: 3 - 103 Aligned: 94 Modelled: 96 Confidence: 95.6% Identity: 7% Fold: Secretion chaperone-like Superfamily: YgaC/TfoX-N like Family: TfoX N-terminal domain-like Phyre2 PDB 3n0k chain A Region: 24 - 79 Aligned: 49 Modelled: 56 Confidence: 52.4% Identity: 18% PDB header:hydrolase inhibitor Chain: A: PDB Molecule:serine protease inhibitor 1; PDBTitle: proteinase inhibitor from coprinopsis cinerea Phyre2 PDB 3rpj chain A Region: 46 - 118 Aligned: 69 Modelled: 73 Confidence: 24.5% Identity: 10% PDB header:transcription regulator Chain: A: PDB Molecule:curlin genes transcriptional regulator; PDBTitle: structure of a curlin genes transcriptional regulator protein from2 proteus mirabilis hi4320. Phyre2 PDB 3s83 chain A Region: 53 - 100 Aligned: 38 Modelled: 48 Confidence: 22.9% Identity: 18% PDB header:signaling protein Chain: A: PDB Molecule:ggdef family protein; PDBTitle: crystal structure of eal domain from caulobacter crescentus cb15 Phyre2 PDB 2rax chain Y Region: 90 - 113 Aligned: 24 Modelled: 24 Confidence: 22.8% Identity: 25% PDB header:cell cycle Chain: Y: PDB Molecule:borealin; PDBTitle: crystal structure of borealin (20-78) bound to survivin (1-120) Phyre2 PDB 1ybx chain A Region: 79 - 118 Aligned: 40 Modelled: 40 Confidence: 17.5% Identity: 10% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: conserved hypothetical protein cth-383 from clostridium thermocellum Phyre2 PDB 2gkp chain A domain 1 Region: 67 - 100 Aligned: 34 Modelled: 34 Confidence: 16.5% Identity: 24% Fold: NMB0488-like Superfamily: NMB0488-like Family: NMB0488-like Phyre2 PDB 1iic chain A domain 1 Region: 4 - 48 Aligned: 42 Modelled: 45 Confidence: 14.1% Identity: 19% Fold: Acyl-CoA N-acyltransferases (Nat) Superfamily: Acyl-CoA N-acyltransferases (Nat) Family: N-myristoyl transferase, NMT Phyre2 PDB 1iyk chain A domain 1 Region: 4 - 48 Aligned: 42 Modelled: 45 Confidence: 13.7% Identity: 19% Fold: Acyl-CoA N-acyltransferases (Nat) Superfamily: Acyl-CoA N-acyltransferases (Nat) Family: N-myristoyl transferase, NMT Phyre2 PDB 2fyf chain B Region: 54 - 107 Aligned: 53 Modelled: 54 Confidence: 11.9% Identity: 13% PDB header:transferase Chain: B: PDB Molecule:phosphoserine aminotransferase; PDBTitle: structure of a putative phosphoserine aminotransferase from2 mycobacterium tuberculosis Phyre2 PDB 2j7q chain A domain 1 Region: 28 - 101 Aligned: 71 Modelled: 74 Confidence: 11.5% Identity: 11% Fold: Cysteine proteinases Superfamily: Cysteine proteinases Family: M48USP-like Phyre2 PDB 1rxt chain A domain 1 Region: 4 - 48 Aligned: 42 Modelled: 45 Confidence: 10.6% Identity: 14% Fold: Acyl-CoA N-acyltransferases (Nat) Superfamily: Acyl-CoA N-acyltransferases (Nat) Family: N-myristoyl transferase, NMT Phyre2 PDB 1xx6 chain A domain 1 Region: 71 - 106 Aligned: 35 Modelled: 36 Confidence: 10.6% Identity: 11% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Type II thymidine kinase Phyre2 PDB 2pst chain X domain 1 Region: 62 - 115 Aligned: 48 Modelled: 54 Confidence: 10.5% Identity: 15% Fold: MbtH/L9 domain-like Superfamily: MbtH-like Family: MbtH-like Phyre2 1 d2fkia1 2 d2a1va1 3 c3h9xB_ 4 d2oc6a1 5 d2i8da1 6 c2kl4A_ 7 d2od0a1 8 c3n0kA_ 9 c3rpjA_ 10 c3s83A_ 11 c2raxY_ 12 c1ybxA_ 13 d2gkpa1 14 d1iica1 15 d1iyka1 16 c2fyfB_ 17 d2j7qa1 18 d1rxta1 19 d1xx6a1 20 d2pstx1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2fkia1 100.0 100 Fold:Secretion chaperone-like Superfamily:YjbR-like Family:YjbR-like 2 d2a1va1 100.0 33 Fold:Secretion chaperone-like Superfamily:YjbR-like Family:YjbR-like 3 c3h9xB_ 100.0 27 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein pspto_3016; PDBTitle: crystal structure of the pspto_3016 protein from2 pseudomonas syringae, northeast structural genomics3 consortium target psr293 4 d2oc6a1 96.9 7 Fold:Secretion chaperone-like Superfamily:YdhG-like Family:YdhG-like 5 d2i8da1 96.7 9 Fold:Secretion chaperone-like Superfamily:YdhG-like Family:YdhG-like 6 c2kl4A_ 96.0 8 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:bh2032 protein; PDBTitle: nmr structure of the protein nb7804a 7 d2od0a1 95.6 7 Fold:Secretion chaperone-like Superfamily:YgaC/TfoX-N like Family:TfoX N-terminal domain-like 8 c3n0kA_ 52.4 18 PDB header:hydrolase inhibitor Chain: A: PDB Molecule:serine protease inhibitor 1; PDBTitle: proteinase inhibitor from coprinopsis cinerea 9 c3rpjA_ 24.5 10 PDB header:transcription regulator Chain: A: PDB Molecule:curlin genes transcriptional regulator; PDBTitle: structure of a curlin genes transcriptional regulator protein from2 proteus mirabilis hi4320. 10 c3s83A_ 22.9 18 PDB header:signaling protein Chain: A: PDB Molecule:ggdef family protein; PDBTitle: crystal structure of eal domain from caulobacter crescentus cb15 11 c2raxY_ 22.8 25 PDB header:cell cycle Chain: Y: PDB Molecule:borealin; PDBTitle: crystal structure of borealin (20-78) bound to survivin (1-120) 12 c1ybxA_ 17.5 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: conserved hypothetical protein cth-383 from clostridium thermocellum 13 d2gkpa1 16.5 24 Fold:NMB0488-like Superfamily:NMB0488-like Family:NMB0488-like 14 d1iica1 14.1 19 Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-myristoyl transferase, NMT 15 d1iyka1 13.7 19 Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-myristoyl transferase, NMT 16 c2fyfB_ 11.9 13 PDB header:transferase Chain: B: PDB Molecule:phosphoserine aminotransferase; PDBTitle: structure of a putative phosphoserine aminotransferase from2 mycobacterium tuberculosis 17 d2j7qa1 11.5 11 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:M48USP-like 18 d1rxta1 10.6 14 Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-myristoyl transferase, NMT 19 d1xx6a1 10.6 11 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Type II thymidine kinase 20 d2pstx1 10.5 15 Fold:MbtH/L9 domain-like Superfamily:MbtH-like Family:MbtH-like 21 d1pu1a_ not modelled 9.9 30 Fold:Hypothetical protein MTH677 Superfamily:Hypothetical protein MTH677 Family:Hypothetical protein MTH677 22 d1o4sa_ not modelled 8.7 13 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:AAT-like 23 d1iwga1 not modelled 8.4 23 Fold:Ferredoxin-like Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 24 d1j98a_ not modelled 8.3 25 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:Autoinducer-2 production protein LuxS 25 d1vjea_ not modelled 8.1 13 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:Autoinducer-2 production protein LuxS 26 d1lq9a_ not modelled 7.7 9 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Actinorhodin biosynthesis monooxygenase ActVa-Orf6 27 c2khrA_ not modelled 7.5 22 PDB header:biosynthetic protein Chain: A: PDB Molecule:protein mbth; PDBTitle: solution structure of rv2377c, a mbth-like protein from mycobacterium2 tuberculosis 28 c2p6fA_ not modelled 7.5 17 PDB header:transferase Chain: A: PDB Molecule:glycylpeptide n-tetradecanoyltransferase; PDBTitle: crystal structures of saccharomyces cerevisiae n-myristoyltransferase2 with bound myristoyl-coa and inhibitors 29 d1j8ba_ not modelled 7.3 16 Fold:YbaB-like Superfamily:YbaB-like Family:YbaB-like 30 c2wuuA_ not modelled 7.2 24 PDB header:transferase Chain: A: PDB Molecule:n-myristoyltransferase; PDBTitle: structure of n-myristoyltransferase from l. donovani 31 c1iylC_ not modelled 7.1 19 PDB header:transferase Chain: C: PDB Molecule:myristoyl-coa:protein n-myristoyltransferase; PDBTitle: crystal structure of candida albicans n-myristoyltransferase with non-2 peptidic inhibitor 32 d157la_ not modelled 7.0 19 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:Phage lysozyme 33 c3ouiA_ not modelled 7.0 20 PDB header:oxidoreductase Chain: A: PDB Molecule:egl nine homolog 1; PDBTitle: phd2-r717 with 40787422 34 d2gpfa1 not modelled 7.0 14 Fold:MbtH/L9 domain-like Superfamily:MbtH-like Family:MbtH-like 35 d1dxha1 not modelled 6.9 17 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 36 d2f2qa1 not modelled 6.7 22 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:Phage lysozyme 37 c3jvvA_ not modelled 6.7 26 PDB header:atp binding protein Chain: A: PDB Molecule:twitching mobility protein; PDBTitle: crystal structure of p. aeruginosa pilt with bound amp-pcp 38 c1ij3A_ not modelled 6.6 21 PDB header:transcription Chain: A: PDB Molecule:general control protein gcn4; PDBTitle: gcn4-pvsl coiled-coil trimer with serine at the a(16)2 position 39 d2glza1 not modelled 6.4 12 Fold:FwdE/GAPDH domain-like Superfamily:FwdE-like Family:FwdE-like 40 c2e8mA_ not modelled 6.3 30 PDB header:signaling protein Chain: A: PDB Molecule:epidermal growth factor receptor kinase PDBTitle: solution structure of the c-terminal sam-domain of2 epidermal growth receptor pathway substrate 8 41 d1igna1 not modelled 6.2 17 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:DNA-binding domain of rap1 42 c1iicA_ not modelled 6.1 19 PDB header:transferase Chain: A: PDB Molecule:peptide n-myristoyltransferase; PDBTitle: crystal structure of saccharomyces cerevisiae n-myristoyltransferase2 with bound myristoylcoa 43 c1wwuA_ not modelled 5.9 30 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein flj21935; PDBTitle: solution structure of the sam_pnt domain of human protein2 flj21935 44 d1ix1a_ not modelled 5.8 33 Fold:Peptide deformylase Superfamily:Peptide deformylase Family:Peptide deformylase 45 c2wzlA_ not modelled 5.7 29 PDB header:viral protein Chain: A: PDB Molecule:phosphoprotein; PDBTitle: the structure of the n-rna binding domain of the mokola2 virus phosphoprotein 46 c1ws1A_ not modelled 5.5 33 PDB header:hydrolase Chain: A: PDB Molecule:peptide deformylase 1; PDBTitle: structure analysis of peptide deformylase from bacillus2 cereus 47 c3qu1B_ not modelled 5.5 25 PDB header:hydrolase, metal binding protein Chain: B: PDB Molecule:peptide deformylase 2; PDBTitle: peptide deformylase from vibrio cholerae 48 c1rxtB_ not modelled 5.4 14 PDB header:transferase Chain: B: PDB Molecule:glycylpeptide n-tetradecanoyltransferase 1; PDBTitle: crystal structure of human myristoyl-coa:protein n-2 myristoyltransferase. 49 d1nyra3 not modelled 5.4 8 Fold:RRF/tRNA synthetase additional domain-like Superfamily:ThrRS/AlaRS common domain Family:Threonyl-tRNA synthetase (ThrRS), second 'additional' domain 50 c3iu2B_ not modelled 5.4 14 PDB header:transferase Chain: B: PDB Molecule:glycylpeptide n-tetradecanoyltransferase 1; PDBTitle: crystal structure of human type-i n-myristoyltransferase with bound2 myristoyl-coa and inhibitor ddd90096 51 c2w3tA_ not modelled 5.4 25 PDB header:hydrolase Chain: A: PDB Molecule:peptide deformylase; PDBTitle: chloro complex of the ni-form of e.coli deformylase 52 d1vyia_ not modelled 5.4 18 Fold:Phosphoprotein M1, C-terminal domain Superfamily:Phosphoprotein M1, C-terminal domain Family:Phosphoprotein M1, C-terminal domain 53 c3oa1B_ not modelled 5.3 18 PDB header:chaperone Chain: B: PDB Molecule:phosphoprotein; PDBTitle: crystal structure of phosphoprotein/protein p/protein m1 residues 69-2 297 from rabies virus reveals degradation to c-terminal domain only 54 d189la_ not modelled 5.2 21 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:Phage lysozyme

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0