Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	L	W	I	N	G	D	W	I	T	G	Q	G	A	S	R	V	K	R	N	P	V	S	G	E	V	L	W	Q	G	N	D	A	D	A	A	Q	V	E	Q	A	C	R	A	A	R	A	A	F	P	R	W	A	R	L	S	F	A	E
Secondary structure
SS confidence
Disorder		?	?																																																					?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	H	A	V	V	E	R	F	A	A	L	L	E	S	N	K	A	E	L	T	A	I	I	A	R	E	T	G	K	P	R	W	E	A	A	T	E	V	T	A	M	I	N	K	I	A	I	S	I	K	A	Y	H	V	R	T	G	E	Q	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	E	M	P	D	G	A	A	S	L	R	H	R	P	H	G	V	L	A	V	F	G	P	Y	N	F	P	G	H	L	P	N	G	H	I	V	P	A	L	L	A	G	N	T	I	I	F	K	P	S	E	L	T	P	W	S	G	E	A	V
Secondary structure
SS confidence
Disorder			?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		M	R	L	W	Q	Q	A	G	L	P	P	G	V	L	N	L	V	Q	G	G	R	E	T	G	Q	A	L	S	A	L	E	D	L	D	G	L	L	F	T	G	S	A	N	T	G	Y	Q	L	H	R	Q	L	S	G	Q	P	E	K	I	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	L	E	M	G	G	N	N	P	L	I	I	D	E	V	A	D	I	D	A	A	V	H	L	T	I	Q	S	A	F	V	T	A	G	Q	R	C	T	C	A	R	R	L	L	L	K	S	G	A	Q	G	D	A	F	L	A	R	L	V	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	S	Q	R	L	T	P	G	N	W	D	D	E	P	Q	P	F	I	G	G	L	I	S	E	Q	A	A	Q	Q	V	V	T	A	W	Q	Q	L	E	A	M	G	G	R	P	L	L	A	P	R	L	L	Q	A	G	T	S	L	L	T	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		G	I	I	E	M	T	G	V	A	G	V	P	D	E	E	V	F	G	P	L	L	R	V	W	R	Y	D	T	F	D	E	A	I	R	M	A	N	N	T	R	F	G	L	S	C	G	L	V	S	P	E	R	E	K	F	D	Q	L	L	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		E	A	R	A	G	I	V	N	W	N	K	P	L	T	G	A	A	S	T	A	P	F	G	G	I	G	A	S	G	N	H	R	P	S	A	W	Y	A	A	D	Y	C	A	W	P	M	A	S	L	E	S	D	S	L	T	L	P	A	T	L
Secondary structure
SS confidence
Disorder																																																						?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.
Sequence		N	P	G	L	D	F	S	D	E	V	V	R
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3ju8 chain B Region: 4 - 484 Aligned: 481 Modelled: 481 Confidence: 100.0% Identity: 62% PDB header:oxidoreductase Chain: B: PDB Molecule:succinylglutamic semialdehyde dehydrogenase; PDBTitle: crystal structure of succinylglutamic semialdehyde dehydrogenase from2 pseudomonas aeruginosa. Phyre2 PDB 2jg7 chain G Region: 2 - 479 Aligned: 474 Modelled: 478 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: G: PDB Molecule:antiquitin; PDBTitle: crystal structure of seabream antiquitin and elucidation of2 its substrate specificity Phyre2 PDB 1a4s chain A Region: 2 - 477 Aligned: 472 Modelled: 476 Confidence: 100.0% Identity: 27% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 1bxs chain A Region: 1 - 469 Aligned: 466 Modelled: 469 Confidence: 100.0% Identity: 28% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 3ed6 chain B Region: 2 - 482 Aligned: 477 Modelled: 481 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: B: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: 1.7 angstrom resolution crystal structure of betaine aldehyde2 dehydrogenase (betb) from staphylococcus aureus Phyre2 PDB 3qan chain B Region: 2 - 473 Aligned: 469 Modelled: 472 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: B: PDB Molecule:1-pyrroline-5-carboxylate dehydrogenase 1; PDBTitle: crystal structure of 1-pyrroline-5-carboxylate dehydrogenase from2 bacillus halodurans Phyre2 PDB 2d4e chain B Region: 1 - 477 Aligned: 473 Modelled: 477 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: B: PDB Molecule:5-carboxymethyl-2-hydroxymuconate semialdehyde PDBTitle: crystal structure of the hpcc from thermus thermophilus hb8 Phyre2 PDB 1uzb chain A Region: 1 - 471 Aligned: 468 Modelled: 471 Confidence: 100.0% Identity: 31% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 2o2q chain A Region: 1 - 469 Aligned: 466 Modelled: 469 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: A: PDB Molecule:formyltetrahydrofolate dehydrogenase; PDBTitle: crystal structure of the c-terminal domain of rat2 10'formyltetrahydrofolate dehydrogenase in complex with nadp Phyre2 PDB 1o9j chain A Region: 2 - 471 Aligned: 467 Modelled: 470 Confidence: 100.0% Identity: 28% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 3iwk chain B Region: 2 - 484 Aligned: 479 Modelled: 483 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: B: PDB Molecule:aminoaldehyde dehydrogenase; PDBTitle: crystal structure of aminoaldehyde dehydrogenase 1 from2 pisum sativum (psamadh1) Phyre2 PDB 1o04 chain A Region: 2 - 481 Aligned: 473 Modelled: 480 Confidence: 100.0% Identity: 27% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 2ve5 chain H Region: 2 - 478 Aligned: 474 Modelled: 477 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: H: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystallographic structure of betaine aldehyde2 dehydrogenase from pseudomonas aeruginosa Phyre2 PDB 1ag8 chain A Region: 2 - 471 Aligned: 467 Modelled: 470 Confidence: 100.0% Identity: 27% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 1t90 chain B Region: 1 - 478 Aligned: 473 Modelled: 478 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: B: PDB Molecule:probable methylmalonate-semialdehyde PDBTitle: crystal structure of methylmalonate semialdehyde2 dehydrogenase from bacillus subtilis Phyre2 PDB 2w8q chain A Region: 1 - 472 Aligned: 468 Modelled: 472 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase, PDBTitle: the crystal structure of human ssadh in complex with ssa. Phyre2 PDB 1ky8 chain A Region: 2 - 477 Aligned: 468 Modelled: 476 Confidence: 100.0% Identity: 23% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 3b4w chain A Region: 2 - 476 Aligned: 470 Modelled: 475 Confidence: 100.0% Identity: 30% PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of mycobacterium tuberculosis aldehyde dehydrogenase2 complexed with nad+ Phyre2 PDB 3r31 chain A Region: 1 - 473 Aligned: 469 Modelled: 473 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: A: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystal structure of betaine aldehyde dehydrogenase from agrobacterium2 tumefaciens Phyre2 PDB 1wnd chain A Region: 2 - 472 Aligned: 466 Modelled: 471 Confidence: 100.0% Identity: 27% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 1 c3ju8B_ 2 c2jg7G_ 3 d1a4sa_ 4 d1bxsa_ 5 c3ed6B_ 6 c3qanB_ 7 c2d4eB_ 8 d1uzba_ 9 c2o2qA_ 10 d1o9ja_ 11 c3iwkB_ 12 d1o04a_ 13 c2ve5H_ 14 d1ag8a_ 15 c1t90B_ 16 c2w8qA_ 17 d1ky8a_ 18 c3b4wA_ 19 c3r31A_ 20 d1wnda_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3ju8B_ 100.0 62 PDB header:oxidoreductase Chain: B: PDB Molecule:succinylglutamic semialdehyde dehydrogenase; PDBTitle: crystal structure of succinylglutamic semialdehyde dehydrogenase from2 pseudomonas aeruginosa. 2 c2jg7G_ 100.0 27 PDB header:oxidoreductase Chain: G: PDB Molecule:antiquitin; PDBTitle: crystal structure of seabream antiquitin and elucidation of2 its substrate specificity 3 d1a4sa_ 100.0 27 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 4 d1bxsa_ 100.0 28 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 5 c3ed6B_ 100.0 26 PDB header:oxidoreductase Chain: B: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: 1.7 angstrom resolution crystal structure of betaine aldehyde2 dehydrogenase (betb) from staphylococcus aureus 6 c3qanB_ 100.0 26 PDB header:oxidoreductase Chain: B: PDB Molecule:1-pyrroline-5-carboxylate dehydrogenase 1; PDBTitle: crystal structure of 1-pyrroline-5-carboxylate dehydrogenase from2 bacillus halodurans 7 c2d4eB_ 100.0 29 PDB header:oxidoreductase Chain: B: PDB Molecule:5-carboxymethyl-2-hydroxymuconate semialdehyde PDBTitle: crystal structure of the hpcc from thermus thermophilus hb8 8 d1uzba_ 100.0 31 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 9 c2o2qA_ 100.0 26 PDB header:oxidoreductase Chain: A: PDB Molecule:formyltetrahydrofolate dehydrogenase; PDBTitle: crystal structure of the c-terminal domain of rat2 10'formyltetrahydrofolate dehydrogenase in complex with nadp 10 d1o9ja_ 100.0 28 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 11 c3iwkB_ 100.0 28 PDB header:oxidoreductase Chain: B: PDB Molecule:aminoaldehyde dehydrogenase; PDBTitle: crystal structure of aminoaldehyde dehydrogenase 1 from2 pisum sativum (psamadh1) 12 d1o04a_ 100.0 27 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 13 c2ve5H_ 100.0 29 PDB header:oxidoreductase Chain: H: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystallographic structure of betaine aldehyde2 dehydrogenase from pseudomonas aeruginosa 14 d1ag8a_ 100.0 27 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 15 c1t90B_ 100.0 26 PDB header:oxidoreductase Chain: B: PDB Molecule:probable methylmalonate-semialdehyde PDBTitle: crystal structure of methylmalonate semialdehyde2 dehydrogenase from bacillus subtilis 16 c2w8qA_ 100.0 29 PDB header:oxidoreductase Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase, PDBTitle: the crystal structure of human ssadh in complex with ssa. 17 d1ky8a_ 100.0 23 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 18 c3b4wA_ 100.0 30 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of mycobacterium tuberculosis aldehyde dehydrogenase2 complexed with nad+ 19 c3r31A_ 100.0 27 PDB header:oxidoreductase Chain: A: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystal structure of betaine aldehyde dehydrogenase from agrobacterium2 tumefaciens 20 d1wnda_ 100.0 27 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 21 c3rh9A_ not modelled 100.0 28 PDB header:oxidoreductase Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase (nad(p)(+)); PDBTitle: the crystal structure of oxidoreductase from marinobacter aquaeolei 22 d1euha_ not modelled 100.0 27 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 23 c3ifgH_ not modelled 100.0 31 PDB header:oxidoreductase Chain: H: PDB Molecule:succinate-semialdehyde dehydrogenase (nadp+); PDBTitle: crystal structure of succinate-semialdehyde dehydrogenase from2 burkholderia pseudomallei, part 1 of 2 24 c3i44A_ not modelled 100.0 27 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from bartonella2 henselae at 2.0a resolution 25 c3prlD_ not modelled 100.0 25 PDB header:oxidoreductase Chain: D: PDB Molecule:nadp-dependent glyceraldehyde-3-phosphate dehydrogenase; PDBTitle: crystal structure of nadp-dependent glyceraldehyde-3-phosphate2 dehydrogenase from bacillus halodurans c-125 26 c3ek1C_ not modelled 100.0 30 PDB header:oxidoreductase Chain: C: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from brucella2 melitensis biovar abortus 2308 27 c3jz4C_ not modelled 100.0 31 PDB header:oxidoreductase Chain: C: PDB Molecule:succinate-semialdehyde dehydrogenase [nadp+]; PDBTitle: crystal structure of e. coli nadp dependent enzyme 28 c2hg2A_ not modelled 100.0 28 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase a; PDBTitle: structure of lactaldehyde dehydrogenase 29 c3k2wD_ not modelled 100.0 24 PDB header:oxidoreductase Chain: D: PDB Molecule:betaine-aldehyde dehydrogenase; PDBTitle: crystal structure of betaine-aldehyde dehydrogenase from2 pseudoalteromonas atlantica t6c 30 c3hazA_ not modelled 100.0 29 PDB header:oxidoreductase Chain: A: PDB Molecule:proline dehydrogenase; PDBTitle: crystal structure of bifunctional proline utilization a2 (puta) protein 31 c3rosA_ not modelled 100.0 21 PDB header:oxidoreductase Chain: A: PDB Molecule:nad-dependent aldehyde dehydrogenase; PDBTitle: crystal structure of nad-dependent aldehyde dehydrogenase from2 lactobacillus acidophilus 32 c3efvC_ not modelled 100.0 24 PDB header:oxidoreductase Chain: C: PDB Molecule:putative succinate-semialdehyde dehydrogenase; PDBTitle: crystal structure of a putative succinate-semialdehyde dehydrogenase2 from salmonella typhimurium lt2 with bound nad 33 c2vroB_ not modelled 100.0 23 PDB header:oxidoreductase Chain: B: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from2 burkholderia xenovorans lb400 34 d1bi9a_ not modelled 100.0 28 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 35 c3r64A_ not modelled 100.0 28 PDB header:oxidoreductase Chain: A: PDB Molecule:nad dependent benzaldehyde dehydrogenase; PDBTitle: crystal structure of a nad-dependent benzaldehyde dehydrogenase from2 corynebacterium glutamicum 36 c3pqaA_ not modelled 100.0 27 PDB header:oxidoreductase Chain: A: PDB Molecule:lactaldehyde dehydrogenase; PDBTitle: crystal structure of glyceraldehyde-3-phosphate dehydrogenase gapn2 from methanocaldococcus jannaschii dsm 2661 37 d1ad3a_ not modelled 100.0 22 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 38 c3v4cB_ not modelled 100.0 27 PDB header:oxidoreductase Chain: B: PDB Molecule:aldehyde dehydrogenase (nadp+); PDBTitle: crystal structure of a semialdehyde dehydrogenase from sinorhizobium2 meliloti 1021 39 d1ez0a_ not modelled 100.0 22 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 40 c3lnsD_ not modelled 100.0 24 PDB header:oxidoreductase Chain: D: PDB Molecule:benzaldehyde dehydrogenase; PDBTitle: benzaldehyde dehydrogenase, a class 3 aldehyde dehydrogenase, with2 bound nadp+ and benzoate adduct 41 c3k9dD_ not modelled 100.0 18 PDB header:oxidoreductase Chain: D: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of probable aldehyde dehydrogenase from listeria2 monocytogenes egd-e 42 d1o20a_ not modelled 100.0 16 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 43 c3my7A_ not modelled 100.0 18 PDB header:oxidoreductase Chain: A: PDB Molecule:alcohol dehydrogenase/acetaldehyde dehydrogenase; PDBTitle: the crystal structure of the acdh domain of an alcohol dehydrogenase2 from vibrio parahaemolyticus to 2.25a 44 c2h5gA_ not modelled 100.0 18 PDB header:oxidoreductase Chain: A: PDB Molecule:delta 1-pyrroline-5-carboxylate synthetase; PDBTitle: crystal structure of human pyrroline-5-carboxylate synthetase 45 d1vlua_ not modelled 100.0 15 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 46 c1vluB_ not modelled 100.0 16 PDB header:oxidoreductase Chain: B: PDB Molecule:gamma-glutamyl phosphate reductase; PDBTitle: crystal structure of gamma-glutamyl phosphate reductase (yor323c) from2 saccharomyces cerevisiae at 2.40 a resolution 47 d1k75a_ not modelled 97.8 18 Fold:ALDH-like Superfamily:ALDH-like Family:L-histidinol dehydrogenase HisD 48 c2crjA_ not modelled 33.7 18 PDB header:gene regulation Chain: A: PDB Molecule:swi/snf-related matrix-associated actin- PDBTitle: solution structure of the hmg domain of mouse hmg domain2 protein hmgx2 49 d1a9xa2 not modelled 31.9 21 Fold:Methylglyoxal synthase-like Superfamily:Methylglyoxal synthase-like Family:Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain 50 d1k99a_ not modelled 31.7 8 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 51 c1j3xA_ not modelled 31.4 14 PDB header:dna binding protein Chain: A: PDB Molecule:high mobility group protein 2; PDBTitle: solution structure of the n-terminal domain of the hmgb2 52 d1j3xa_ not modelled 31.4 14 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 53 c2yukA_ not modelled 30.8 19 PDB header:transferase Chain: A: PDB Molecule:myeloid/lymphoid or mixed-lineage leukemia PDBTitle: solution structure of the hmg box of human myeloid/lymphoid2 or mixed-lineage leukemia protein 3 homolog 54 c2eqzA_ not modelled 30.3 18 PDB header:transcription Chain: A: PDB Molecule:high mobility group protein b3; PDBTitle: solution structure of the first hmg-box domain from high2 mobility group protein b3 55 d1u0ta_ not modelled 29.9 15 Fold:NAD kinase/diacylglycerol kinase-like Superfamily:NAD kinase/diacylglycerol kinase-like Family:NAD kinase-like 56 c3jtpB_ not modelled 29.0 27 PDB header:protein binding Chain: B: PDB Molecule:adapter protein meca 1; PDBTitle: crystal structure of the c-terminal domain of meca 57 c3fghA_ not modelled 28.6 13 PDB header:transcription Chain: A: PDB Molecule:transcription factor a, mitochondrial; PDBTitle: human mitochondrial transcription factor a box b 58 d2lefa_ not modelled 26.6 17 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 59 d2bona1 not modelled 25.0 14 Fold:NAD kinase/diacylglycerol kinase-like Superfamily:NAD kinase/diacylglycerol kinase-like Family:Diacylglycerol kinase-like 60 d1j46a_ not modelled 24.9 14 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 61 c2cs1A_ not modelled 22.6 21 PDB header:dna binding protein Chain: A: PDB Molecule:pms1 protein homolog 1; PDBTitle: solution structure of the hmg domain of human dna mismatch2 repair protein 62 d1hsma_ not modelled 22.4 16 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 63 d1lwma_ not modelled 21.7 13 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 64 c2yvqA_ not modelled 21.3 8 PDB header:ligase Chain: A: PDB Molecule:carbamoyl-phosphate synthase; PDBTitle: crystal structure of mgs domain of carbamoyl-phosphate2 synthetase from homo sapiens 65 c3u2bC_ not modelled 20.9 14 PDB header:transcription/dna Chain: C: PDB Molecule:transcription factor sox-4; PDBTitle: structure of the sox4 hmg domain bound to dna 66 c3nrlB_ not modelled 20.9 9 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein rumgna_01417; PDBTitle: crystal structure of protein rumgna_01417 from ruminococcus gnavus,2 northeast structural genomics consortium target ugr76 67 d1gt0d_ not modelled 20.2 17 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 68 d1ckta_ not modelled 19.5 17 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 69 d1u2ca2 not modelled 19.5 14 Fold:Dystroglycan, domain 2 Superfamily:Dystroglycan, domain 2 Family:Dystroglycan, domain 2 70 d1v64a_ not modelled 19.4 18 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 71 d1s7ia_ not modelled 19.2 11 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:DGPF domain (Pfam 04946) 72 d1v63a_ not modelled 19.1 16 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 73 c2co9A_ not modelled 18.5 15 PDB header:transcription Chain: A: PDB Molecule:thymus high mobility group box protein tox; PDBTitle: solution structure of the hmg_box domain of thymus high2 mobility group box protein tox from mouse 74 c1hmfA_ not modelled 18.3 14 PDB header:dna-binding Chain: A: PDB Molecule:high mobility group protein fragment-b; PDBTitle: structure of the hmg box motif in the b-domain of hmg1 75 d1hmfa_ not modelled 18.3 14 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 76 c2yulA_ not modelled 18.2 19 PDB header:transcription Chain: A: PDB Molecule:transcription factor sox-17; PDBTitle: solution structure of the hmg box of human transcription2 factor sox-17 77 d1j3da_ not modelled 18.0 18 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 78 c3g5oC_ not modelled 17.7 24 PDB header:toxin/antitoxin Chain: C: PDB Molecule:uncharacterized protein rv2866; PDBTitle: the crystal structure of the toxin-antitoxin complex relbe2 (rv2865-2 2866) from mycobacterium tuberculosis 79 d1s99a_ not modelled 17.1 11 Fold:Ferredoxin-like Superfamily:MTH1187/YkoF-like Family:Putative thiamin/HMP-binding protein YkoF 80 d1t0tv_ not modelled 16.7 28 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Chlorite dismutase-like 81 d1vdha_ not modelled 16.5 21 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Chlorite dismutase-like 82 c3labA_ not modelled 16.4 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate) PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica 83 c2lhjA_ not modelled 15.7 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:high mobility group protein homolog nhp1; PDBTitle: nmr structure of the high mobility group protein-like protein nhp12 from babesia bovis t2bo (baboa.00841.a) 84 c3v4gA_ not modelled 15.1 13 PDB header:dna binding protein Chain: A: PDB Molecule:arginine repressor; PDBTitle: 1.60 angstrom resolution crystal structure of an arginine repressor2 from vibrio vulnificus cmcp6 85 c3gyyC_ not modelled 14.9 11 PDB header:transport protein Chain: C: PDB Molecule:periplasmic substrate binding protein; PDBTitle: the ectoine binding protein of the teaabc trap transporter teaa in the2 apo-state 86 d2jgra1 not modelled 14.5 14 Fold:NAD kinase/diacylglycerol kinase-like Superfamily:NAD kinase/diacylglycerol kinase-like Family:Diacylglycerol kinase-like 87 d2tpta3 not modelled 14.5 23 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 88 d2gzka2 not modelled 14.4 14 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 89 c1hrzA_ not modelled 14.4 14 PDB header:dna binding protein/dna Chain: A: PDB Molecule:human sry; PDBTitle: the 3d structure of the human sry-dna complex solved by2 multi-dimensional heteronuclear-edited and-filtered nmr 90 c1hryA_ not modelled 14.4 14 PDB header:dna binding protein/dna Chain: A: PDB Molecule:human sry; PDBTitle: the 3d structure of the human sry-dna complex solved by2 multid-dimensional heteronuclear-edited and-filtered nmr 91 c2e6oA_ not modelled 13.6 23 PDB header:transcription, cell cycle Chain: A: PDB Molecule:hmg box-containing protein 1; PDBTitle: solution structure of the hmg box domain from human hmg-box2 transcription factor 1 92 c3e7hA_ not modelled 13.4 17 PDB header:transferase Chain: A: PDB Molecule:dna-directed rna polymerase subunit beta; PDBTitle: the crystal structure of the beta subunit of the dna-2 directed rna polymerase from vibrio cholerae o1 biovar3 eltor 93 d1xxaa_ not modelled 13.2 19 Fold:DCoH-like Superfamily:C-terminal domain of arginine repressor Family:C-terminal domain of arginine repressor 94 d1wu2a3 not modelled 13.2 16 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MoeA central domain-like 95 c2bonB_ not modelled 13.0 14 PDB header:transferase Chain: B: PDB Molecule:lipid kinase; PDBTitle: structure of an escherichia coli lipid kinase (yegs) 96 c3qwuA_ not modelled 13.0 18 PDB header:ligase Chain: A: PDB Molecule:dna ligase; PDBTitle: putative atp-dependent dna ligase from aquifex aeolicus. 97 d1y5ea1 not modelled 12.6 26 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 98 c1usdA_ not modelled 12.5 21 PDB header:signaling protein Chain: A: PDB Molecule:vasodilator-stimulated phosphoprotein; PDBTitle: human vasp tetramerisation domain l352m 99 c2ec4A_ not modelled 12.1 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:fas-associated factor 1; PDBTitle: solution structure of the uas domain from human fas-2 associated factor 1

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0