Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0AD30
DateThu Jan 5 11:19:49 GMT 2012
Unique Job ID80889a71e50457b8

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3lrcC_
Top template information
PDB header:transport protein
Chain: C: PDB Molecule:arginine/agmatine antiporter;
PDBTitle: structure of e. coli adic (p1)
Confidence and coverage
Confidence: 14.9% Coverage: 30%
80 residues ( 30% of your sequence) have been modelled with 14.9% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Please note: You must be registered and logged in to use Phyrealarm.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  METFNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALMAAGMSPANALATNKLQ
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   .........70.........80.........90.........100.........110.........120
Sequence  ACGGSISATIYFIRRKVVSLSDQKLNIAMTFVGSMSGALLVQYVQADVLRQILPILVICI
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   .........130.........140.........150.........160.........170.........180
Sequence  GLYFLLMPKLGEEDRQRRMYGLPFALIAGGCVGFYDGFFGPAAGSFYALAFVTLCGFNLA
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   .........190.........200.........210.........220.........230.........240
Sequence  KATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARMGSRLVLSKGQKLIRP
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   .........250.........260.........
Sequence  MIVIVSAVMSAKLLYDSHGQEILHWLGMN
Secondary structure 



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????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3lrc chain C

3D model

Region: 54 - 134
Aligned: 80
Modelled: 81
Confidence: 14.9%
Identity: 10%
PDB header:transport protein
Chain: C: PDB Molecule:arginine/agmatine antiporter;
PDBTitle: structure of e. coli adic (p1)

Phyre2

PDB 3gia chain A

3D model

Region: 36 - 140
Aligned: 105
Modelled: 105
Confidence: 13.6%
Identity: 10%
PDB header:transport protein
Chain: A: PDB Molecule:uncharacterized protein mj0609;
PDBTitle: crystal structure of apct transporter

Phyre2

PDB 1j4n chain A

3D model

Region: 65 - 157
Aligned: 93
Modelled: 93
Confidence: 11.7%
Identity: 11%
Fold: Aquaporin-like
Superfamily: Aquaporin-like
Family: Aquaporin-like

Phyre2

PDB 2j83 chain B

3D model

Region: 256 - 268
Aligned: 13
Modelled: 13
Confidence: 9.1%
Identity: 38%
PDB header:hydrolase
Chain: B: PDB Molecule:ulilysin;
PDBTitle: ulilysin metalloprotease in complex with batimastat.

Phyre2

PDB 3llq chain B

3D model

Region: 65 - 236
Aligned: 138
Modelled: 143
Confidence: 8.9%
Identity: 13%
PDB header:membrane protein
Chain: B: PDB Molecule:aquaporin z 2;
PDBTitle: aquaporin structure from plant pathogen agrobacterium tumerfaciens

Phyre2

PDB 1fx8 chain A

3D model

Region: 65 - 154
Aligned: 90
Modelled: 90
Confidence: 8.7%
Identity: 12%
Fold: Aquaporin-like
Superfamily: Aquaporin-like
Family: Aquaporin-like

Phyre2

PDB 2d57 chain A

3D model

Region: 65 - 163
Aligned: 99
Modelled: 99
Confidence: 7.0%
Identity: 17%
PDB header:transport protein
Chain: A: PDB Molecule:aquaporin-4;
PDBTitle: double layered 2d crystal structure of aquaporin-4 (aqp4m23) at 3.2 a2 resolution by electron crystallography

Phyre2

PDB 1lda chain A

3D model

Region: 65 - 238
Aligned: 154
Modelled: 168
Confidence: 6.5%
Identity: 18%
PDB header:transport protein
Chain: A: PDB Molecule:glycerol uptake facilitator protein;
PDBTitle: crystal structure of the e. coli glycerol facilitator (glpf) without2 substrate glycerol

Phyre2

PDB 1ymg chain A domain 1

3D model

Region: 65 - 157
Aligned: 93
Modelled: 93
Confidence: 6.5%
Identity: 15%
Fold: Aquaporin-like
Superfamily: Aquaporin-like
Family: Aquaporin-like

Phyre2

PDB 1ymg chain A

3D model

Region: 65 - 157
Aligned: 93
Modelled: 93
Confidence: 6.5%
Identity: 15%
PDB header:membrane protein
Chain: A: PDB Molecule:lens fiber major intrinsic protein;
PDBTitle: the channel architecture of aquaporin o at 2.2 angstrom resolution

Phyre2

PDB 3klz chain E

3D model

Region: 18 - 104
Aligned: 87
Modelled: 87
Confidence: 6.3%
Identity: 17%
PDB header:membrane protein
Chain: E: PDB Molecule:putative formate transporter 1;
PDBTitle: pentameric formate channel with formate bound

Phyre2

PDB 1cii chain A

3D model

Region: 193 - 235
Aligned: 43
Modelled: 43
Confidence: 6.2%
Identity: 16%
PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia

Phyre2

PDB 1u7g chain A

3D model

Region: 50 - 205
Aligned: 155
Modelled: 156
Confidence: 5.9%
Identity: 12%
Fold: Ammonium transporter
Superfamily: Ammonium transporter
Family: Ammonium transporter

Phyre2

PDB 3c02 chain A

3D model

Region: 65 - 233
Aligned: 152
Modelled: 169
Confidence: 5.8%
Identity: 16%
PDB header:membrane protein
Chain: A: PDB Molecule:aquaglyceroporin;
PDBTitle: x-ray structure of the aquaglyceroporin from plasmodium falciparum

Phyre2

PDB 3hfw chain A

3D model

Region: 216 - 241
Aligned: 26
Modelled: 26
Confidence: 5.7%
Identity: 8%
PDB header:hydrolase
Chain: A: PDB Molecule:protein adp-ribosylarginine hydrolase;
PDBTitle: crystal structure of human adp-ribosylhydrolase 1 (harh1)

Phyre2

PDB 1rc2 chain A

3D model

Region: 65 - 201
Aligned: 137
Modelled: 137
Confidence: 5.6%
Identity: 10%
Fold: Aquaporin-like
Superfamily: Aquaporin-like
Family: Aquaporin-like

Phyre2

PDB 1h6i chain A

3D model

Region: 65 - 163
Aligned: 99
Modelled: 99
Confidence: 5.5%
Identity: 8%
Fold: Aquaporin-like
Superfamily: Aquaporin-like
Family: Aquaporin-like

Phyre2

PDB 2ht2 chain B

3D model

Region: 71 - 257
Aligned: 165
Modelled: 174
Confidence: 5.5%
Identity: 11%
PDB header:membrane protein
Chain: B: PDB Molecule:h(+)/cl(-) exchange transporter clca;
PDBTitle: structure of the escherichia coli clc chloride channel2 y445h mutant and fab complex

Phyre2

PDB 3g9d chain B

3D model

Region: 216 - 241
Aligned: 26
Modelled: 26
Confidence: 5.4%
Identity: 19%
PDB header:hydrolase
Chain: B: PDB Molecule:dinitrogenase reductase activacting
PDBTitle: crystal structure glycohydrolase

Phyre2

PDB 2jp3 chain A

3D model

Region: 111 - 142
Aligned: 32
Modelled: 32
Confidence: 5.3%
Identity: 16%
PDB header:transcription
Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4;
PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles

Phyre2
1

c3lrcC_
2

c3giaA_
3

d1j4na_
4

c2j83B_
5

c3llqB_
6

d1fx8a_
7

c2d57A_
8

c1ldaA_
9

d1ymga1
10

c1ymgA_
11

c3klzE_
12

c1ciiA_
13

d1u7ga_
14

c3c02A_
15

c3hfwA_
16

d1rc2a_
17

d1h6ia_
18

c2ht2B_
19

c3g9dB_
20

c2jp3A_
21






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3lrcC_



14.9 10 PDB header:transport protein
Chain: C: PDB Molecule:arginine/agmatine antiporter;
PDBTitle: structure of e. coli adic (p1)
2c3giaA_



13.6 10 PDB header:transport protein
Chain: A: PDB Molecule:uncharacterized protein mj0609;
PDBTitle: crystal structure of apct transporter
3d1j4na_



11.7 11 Fold:Aquaporin-like
Superfamily:Aquaporin-like
Family:Aquaporin-like
4c2j83B_



9.1 38 PDB header:hydrolase
Chain: B: PDB Molecule:ulilysin;
PDBTitle: ulilysin metalloprotease in complex with batimastat.
5c3llqB_



8.9 13 PDB header:membrane protein
Chain: B: PDB Molecule:aquaporin z 2;
PDBTitle: aquaporin structure from plant pathogen agrobacterium tumerfaciens
6d1fx8a_



8.7 12 Fold:Aquaporin-like
Superfamily:Aquaporin-like
Family:Aquaporin-like
7c2d57A_



7.0 17 PDB header:transport protein
Chain: A: PDB Molecule:aquaporin-4;
PDBTitle: double layered 2d crystal structure of aquaporin-4 (aqp4m23) at 3.2 a2 resolution by electron crystallography
8c1ldaA_



6.5 18 PDB header:transport protein
Chain: A: PDB Molecule:glycerol uptake facilitator protein;
PDBTitle: crystal structure of the e. coli glycerol facilitator (glpf) without2 substrate glycerol
9d1ymga1



6.5 15 Fold:Aquaporin-like
Superfamily:Aquaporin-like
Family:Aquaporin-like
10c1ymgA_



6.5 15 PDB header:membrane protein
Chain: A: PDB Molecule:lens fiber major intrinsic protein;
PDBTitle: the channel architecture of aquaporin o at 2.2 angstrom resolution
11c3klzE_



6.3 17 PDB header:membrane protein
Chain: E: PDB Molecule:putative formate transporter 1;
PDBTitle: pentameric formate channel with formate bound
12c1ciiA_



6.2 16 PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
13d1u7ga_



5.9 12 Fold:Ammonium transporter
Superfamily:Ammonium transporter
Family:Ammonium transporter
14c3c02A_



5.8 16 PDB header:membrane protein
Chain: A: PDB Molecule:aquaglyceroporin;
PDBTitle: x-ray structure of the aquaglyceroporin from plasmodium falciparum
15c3hfwA_



5.7 8 PDB header:hydrolase
Chain: A: PDB Molecule:protein adp-ribosylarginine hydrolase;
PDBTitle: crystal structure of human adp-ribosylhydrolase 1 (harh1)
16d1rc2a_



5.6 10 Fold:Aquaporin-like
Superfamily:Aquaporin-like
Family:Aquaporin-like
17d1h6ia_



5.5 8 Fold:Aquaporin-like
Superfamily:Aquaporin-like
Family:Aquaporin-like
18c2ht2B_



5.5 11 PDB header:membrane protein
Chain: B: PDB Molecule:h(+)/cl(-) exchange transporter clca;
PDBTitle: structure of the escherichia coli clc chloride channel2 y445h mutant and fab complex
19c3g9dB_



5.4 19 PDB header:hydrolase
Chain: B: PDB Molecule:dinitrogenase reductase activacting
PDBTitle: crystal structure glycohydrolase
20c2jp3A_



5.3 16 PDB header:transcription
Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4;
PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles
21d1kqfb2



not modelled 5.2 12 Fold:Single transmembrane helix
Superfamily:Iron-sulfur subunit of formate dehydrogenase N, transmembrane anchor
Family:Iron-sulfur subunit of formate dehydrogenase N, transmembrane anchor

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0