Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	K	N	S	Y	L	L	S	C	L	A	I	A	V	S	S	A	C	H	A	E	V	L	T	Y	P	D	P	L	G	S	S	Q	S	D	F	G	G	T	G	L	L	Q	M	P	N	A	R	I	A	P	E	G	E	F	S	V	N	Y
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?													?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?				?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	D	N	D	Q	Y	R	F	Y	S	T	S	V	A	L	F	P	W	L	E	G	T	I	R	Y	T	D	V	R	T	R	K	Y	S	Q	W	E	D	F	S	G	D	Q	S	Y	K	D	K	S	F	D	F	K	L	R	L	W	E	E	G
Secondary structure
SS confidence
Disorder																																?		?	?					?	?	?	?		?															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Y	W	L	P	Q	V	A	F	G	K	R	D	I	A	G	T	G	L	F	D	G	E	Y	L	V	A	S	K	Q	A	G	P	F	D	F	T	L	G	M	A	W	G	Y	A	G	N	A	G	N	I	T	N	P	F	C	R	V	S	D	K
Secondary structure
SS confidence
Disorder																			?																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Y	C	H	R	A	E	S	H	D	A	G	D	I	S	F	S	D	I	F	R	G	P	A	S	I	F	G	G	I	E	Y	Q	T	P	W	N	P	L	R	L	K	L	E	Y	D	G	N	N	Y	Q	N	D	F	A	G	K	L	P	Q	A
Secondary structure
SS confidence
Disorder					?	?		?	?	?	?								?																															?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	H	F	N	V	G	A	V	Y	R	A	A	S	W	A	D	L	N	L	S	Y	E	R	G	N	T	L	M	F	G	F	T	L	R	T	N	F	N	D	L	R	P	A	L	R	D	T	P	K	P	A	Y	Q	P	A	P	E	S	E	G
Secondary structure
SS confidence
Disorder																																						?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	Q	Y	T	T	V	A	N	Q	L	T	A	L	K	Y	N	A	G	F	D	A	P	E	I	Q	L	R	D	K	T	L	Y	M	S	G	Q	Q	Y	K	Y	R	D	S	R	E	A	V	D	R	A	N	R	I	L	V	N	N	L	P	Q
Secondary structure
SS confidence
Disorder		?	?															?						?	?			?	?													?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		G	V	E	K	I	S	V	T	Q	K	R	E	H	M	A	M	V	T	T	E	T	D	V	A	S	L	R	K	Q	L	A	G	T	A	P	G	Q	S	E	P	L	Q	Q	Q	R	V	E	A	E	D	L	S	A	F	G	R	G	Y	R	I
Secondary structure
SS confidence
Disorder													?																														?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		R	E	D	R	F	S	Y	S	F	N	P	T	L	S	Q	S	L	G	G	P	E	D	F	Y	M	F	Q	L	G	L	M	S	S	A	R	Y	W	F	T	D	H	L	L	L	D	G	G	I	F	T	N	I	Y	N	N	Y	D	K	F	K
Secondary structure
SS confidence
Disorder					?																										?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		S	S	L	L	P	A	D	S	T	L	P	R	V	R	T	H	I	R	D	Y	V	R	N	D	V	Y	L	N	N	L	Q	A	N	Y	F	A	D	L	G	N	G	F	Y	G	Q	V	Y	G	G	Y	L	E	T	M	Y	A	G	V	G	S
Secondary structure
SS confidence
Disorder					?	?		?	?																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		E	L	L	Y	R	P	L	D	A	C	W	A	L	G	V	D	V	N	Y	V	K	Q	R	D	W	D	N	M	M	R	F	T	D	Y	S	T	P	T	G	F	V	T	A	Y	W	N	P	P	T	L	N	G	V	L	M	K	L	S	V	G
Secondary structure
SS confidence
Disorder																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		Q	Y	L	A	K	D	K	G	A	T	I	D	V	A	K	R	F	D	S	G	V	A	V	G	V	W	A	A	I	S	N	V	S	K	D	D	Y	G	E	G	G	F	S	K	G	F	Y	I	S	I	P	F	D	L	M	T	I	G	P	N
Secondary structure
SS confidence
Disorder																																	?	?	?	?	?	?	?	?	?	?	?											?		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.
Sequence		R	N	R	A	V	V	S	W	T	P	L	T	R	D	G	G	Q	M	L	S	R	K	Y	Q	L	Y	P	M	T	A	E	R	E	V	P	V	G	Q
Secondary structure
SS confidence
Disorder		?		?															?	?	?	?	?										?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2k0l chain A Region: 68 - 295 Aligned: 152 Modelled: 154 Confidence: 95.0% Identity: 22% PDB header:membrane protein Chain: A: PDB Molecule:outer membrane protein a; PDBTitle: nmr structure of the transmembrane domain of the outer2 membrane protein a from klebsiella pneumoniae in dhpc3 micelles. Phyre2 PDB 3bry chain B Region: 199 - 276 Aligned: 77 Modelled: 77 Confidence: 94.2% Identity: 25% PDB header:transport protein Chain: B: PDB Molecule:tbux; PDBTitle: crystal structure of the ralstonia pickettii toluene2 transporter tbux Phyre2 PDB 1p4t chain A Region: 68 - 251 Aligned: 125 Modelled: 133 Confidence: 76.7% Identity: 10% Fold: Transmembrane beta-barrels Superfamily: OMPA-like Family: Outer membrane protein Phyre2 PDB 3dwo chain X Region: 11 - 278 Aligned: 234 Modelled: 234 Confidence: 73.9% Identity: 15% PDB header:membrane protein Chain: X: PDB Molecule:probable outer membrane protein; PDBTitle: crystal structure of a pseudomonas aeruginosa fadl homologue Phyre2 PDB 1pho chain A Region: 134 - 251 Aligned: 91 Modelled: 92 Confidence: 71.6% Identity: 19% Fold: Transmembrane beta-barrels Superfamily: Porins Family: Porin Phyre2 PDB 3nb3 chain C Region: 54 - 251 Aligned: 123 Modelled: 144 Confidence: 62.1% Identity: 21% PDB header:virus Chain: C: PDB Molecule:outer membrane protein a; PDBTitle: the host outer membrane proteins ompa and ompc are packed at specific2 sites in the shigella phage sf6 virion as structural components Phyre2 PDB 1qjp chain A Region: 70 - 251 Aligned: 106 Modelled: 127 Confidence: 46.3% Identity: 24% Fold: Transmembrane beta-barrels Superfamily: OMPA-like Family: Outer membrane protein Phyre2 PDB 2x27 chain X Region: 151 - 251 Aligned: 88 Modelled: 100 Confidence: 44.2% Identity: 10% PDB header:membrane protein Chain: X: PDB Molecule:outer membrane protein oprg; PDBTitle: crystal structure of the outer membrane protein oprg from2 pseudomonas aeruginosa Phyre2 PDB 3a2r chain X Region: 139 - 277 Aligned: 116 Modelled: 116 Confidence: 42.0% Identity: 15% PDB header:membrane protein Chain: X: PDB Molecule:outer membrane protein ii; PDBTitle: crystal structure of outer membrane protein porb from neisseria2 meningitidis Phyre2 PDB 2jvf chain A Region: 307 - 336 Aligned: 30 Modelled: 30 Confidence: 41.0% Identity: 7% PDB header:de novo protein Chain: A: PDB Molecule:de novo protein m7; PDBTitle: solution structure of m7, a computationally-designed2 artificial protein Phyre2 PDB 2jmm chain A Region: 50 - 254 Aligned: 145 Modelled: 161 Confidence: 37.4% Identity: 10% PDB header:membrane protein Chain: A: PDB Molecule:outer membrane protein a; PDBTitle: nmr solution structure of a minimal transmembrane beta-2 barrel platform protein Phyre2 PDB 1qys chain A Region: 307 - 336 Aligned: 30 Modelled: 30 Confidence: 35.8% Identity: 20% PDB header:de novo protein Chain: A: PDB Molecule:top7; PDBTitle: crystal structure of top7: a computationally designed2 protein with a novel fold Phyre2 PDB 1t16 chain A Region: 71 - 263 Aligned: 160 Modelled: 172 Confidence: 35.7% Identity: 13% Fold: Transmembrane beta-barrels Superfamily: Porins Family: Outer membrane protein transport protein Phyre2 PDB 3qra chain A Region: 50 - 251 Aligned: 140 Modelled: 150 Confidence: 30.3% Identity: 19% PDB header:cell invasion Chain: A: PDB Molecule:attachment invasion locus protein; PDBTitle: the crystal structure of ail, the attachment invasion locus protein of2 yersinia pestis Phyre2 PDB 2lhf chain A Region: 155 - 251 Aligned: 74 Modelled: 75 Confidence: 26.8% Identity: 23% PDB header:membrane protein Chain: A: PDB Molecule:outer membrane protein h1; PDBTitle: solution structure of outer membrane protein h (oprh) from p.2 aeruginosa in dhpc micelles Phyre2 PDB 1ynj chain A domain 1 Region: 319 - 358 Aligned: 40 Modelled: 40 Confidence: 26.4% Identity: 23% Fold: DCoH-like Superfamily: RBP11-like subunits of RNA polymerase Family: RNA polymerase alpha subunit dimerisation domain Phyre2 PDB 2f1t chain B Region: 38 - 251 Aligned: 156 Modelled: 157 Confidence: 26.0% Identity: 13% PDB header:membrane protein Chain: B: PDB Molecule:outer membrane protein w; PDBTitle: outer membrane protein ompw Phyre2 PDB 2zfg chain A domain 1 Region: 140 - 251 Aligned: 85 Modelled: 86 Confidence: 22.2% Identity: 19% Fold: Transmembrane beta-barrels Superfamily: Porins Family: Porin Phyre2 PDB 1g90 chain A Region: 521 - 660 Aligned: 139 Modelled: 140 Confidence: 20.6% Identity: 13% Fold: Transmembrane beta-barrels Superfamily: OMPA-like Family: Outer membrane protein Phyre2 PDB 2fgq chain X domain 1 Region: 140 - 277 Aligned: 105 Modelled: 110 Confidence: 19.9% Identity: 20% Fold: Transmembrane beta-barrels Superfamily: Porins Family: Porin Phyre2 1 c2k0lA_ 2 c3bryB_ 3 d1p4ta_ 4 c3dwoX_ 5 d1phoa_ 6 c3nb3C_ 7 d1qjpa_ 8 c2x27X_ 9 c3a2rX_ 10 c2jvfA_ 11 c2jmmA_ 12 c1qysA_ 13 d1t16a_ 14 c3qraA_ 15 c2lhfA_ 16 d1ynja1 17 c2f1tB_ 18 d2zfga1 19 d1g90a_ 20 d2fgqx1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54