Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	S	G	H	R	F	D	A	Q	T	L	H	S	F	I	Q	A	V	F	R	Q	M	G	S	E	E	Q	E	A	K	L	V	A	D	H	L	I	A	A	N	L	A	G	H	D	S	H	G	I	G	M	I	P	S	Y	V	R	S	W
Secondary structure
SS confidence
Disorder		?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	Q	G	H	L	Q	I	N	H	H	A	K	T	V	K	E	A	G	A	A	V	T	L	D	G	D	R	A	F	G	Q	V	A	A	H	E	A	M	A	L	G	I	E	K	A	H	Q	H	G	I	A	A	V	A	L	H	N	S	H	H
Secondary structure
SS confidence
Disorder						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	G	R	I	G	Y	W	A	E	Q	C	A	A	A	G	F	V	S	I	H	F	V	S	V	V	G	I	P	M	V	A	P	F	H	G	R	D	S	R	F	G	T	N	P	F	C	V	V	F	P	R	K	D	N	F	P	L	L	L	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Y	A	T	S	A	I	A	F	G	K	T	R	V	A	W	H	K	G	V	P	V	P	P	G	C	L	I	D	V	N	G	V	P	T	T	N	P	A	V	M	Q	E	S	P	L	G	S	L	L	T	F	A	E	H	K	G	Y	A	L	A
Secondary structure
SS confidence
Disorder				?	?		?	?										?																										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	M	C	E	I	L	G	G	A	L	S	G	G	K	T	T	H	Q	E	T	L	Q	T	S	P	D	A	I	L	N	C	M	T	T	I	I	I	N	P	E	L	F	G	A	P	D	C	N	A	Q	T	E	A	F	A	E	W	V	K	A
Secondary structure
SS confidence
Disorder														?	?		?	?		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		S	P	H	D	D	D	K	P	I	L	L	P	G	E	W	E	V	N	T	R	R	E	R	Q	K	Q	G	I	P	L	D	A	G	S	W	Q	A	I	C	D	A	A	R	Q	I	G	M	P	E	E	T	L	Q	A	F	C	Q	Q	L	A
Secondary structure
SS confidence
Disorder				?		?	?	?																			?	?		?																														?	?
Disorder confidence
		.
Sequence		S
Secondary structure
SS confidence
Disorder		?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2g8y chain B Region: 5 - 361 Aligned: 357 Modelled: 357 Confidence: 100.0% Identity: 97% PDB header:oxidoreductase Chain: B: PDB Molecule:malate/l-lactate dehydrogenases; PDBTitle: the structure of a putative malate/lactate dehydrogenase from e. coli. Phyre2 PDB 3i0p chain A Region: 4 - 350 Aligned: 345 Modelled: 347 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of malate dehydrogenase from entamoeba histolytica Phyre2 PDB 1z2i chain A Region: 4 - 350 Aligned: 340 Modelled: 347 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of agrobacterium tumefaciens malate2 dehydrogenase, new york structural genomics consortium Phyre2 PDB 1vbi chain A Region: 6 - 349 Aligned: 335 Modelled: 344 Confidence: 100.0% Identity: 31% PDB header:oxidoreductase Chain: A: PDB Molecule:type 2 malate/lactate dehydrogenase; PDBTitle: crystal structure of type 2 malate/lactate dehydrogenase from thermus2 thermophilus hb8 Phyre2 PDB 1rfm chain A Region: 7 - 351 Aligned: 337 Modelled: 345 Confidence: 100.0% Identity: 32% Fold: L-sulfolactate dehydrogenase-like Superfamily: L-sulfolactate dehydrogenase-like Family: L-sulfolactate dehydrogenase-like Phyre2 PDB 1xrh chain A Region: 4 - 350 Aligned: 339 Modelled: 347 Confidence: 100.0% Identity: 28% Fold: L-sulfolactate dehydrogenase-like Superfamily: L-sulfolactate dehydrogenase-like Family: L-sulfolactate dehydrogenase-like Phyre2 PDB 1wtj chain B Region: 2 - 342 Aligned: 332 Modelled: 341 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: B: PDB Molecule:ureidoglycolate dehydrogenase; PDBTitle: crystal structure of delta1-piperideine-2-carboxylate2 reductase from pseudomonas syringae pvar.tomato Phyre2 PDB 1nxu chain A Region: 5 - 341 Aligned: 330 Modelled: 336 Confidence: 100.0% Identity: 24% Fold: L-sulfolactate dehydrogenase-like Superfamily: L-sulfolactate dehydrogenase-like Family: L-sulfolactate dehydrogenase-like Phyre2 PDB 1v9n chain A Region: 2 - 349 Aligned: 330 Modelled: 348 Confidence: 100.0% Identity: 32% PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: structure of malate dehydrogenase from pyrococcus horikoshii ot3 Phyre2 PDB 3uoe chain B Region: 3 - 342 Aligned: 316 Modelled: 322 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: B: PDB Molecule:dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from sinorhizobium meliloti Phyre2 PDB 1jmx chain A domain 1 Region: 312 - 354 Aligned: 43 Modelled: 43 Confidence: 40.9% Identity: 14% Fold: Cytochrome c Superfamily: Cytochrome c Family: Quinohemoprotein amine dehydrogenase A chain, domains 1 and 2 Phyre2 PDB 3irv chain A Region: 65 - 120 Aligned: 56 Modelled: 56 Confidence: 38.1% Identity: 9% PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a Phyre2 PDB 3eef chain A Region: 76 - 120 Aligned: 45 Modelled: 44 Confidence: 34.6% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum Phyre2 PDB 3kl2 chain K Region: 76 - 120 Aligned: 45 Modelled: 45 Confidence: 34.5% Identity: 13% PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis Phyre2 PDB 2qiw chain A Region: 14 - 120 Aligned: 88 Modelled: 107 Confidence: 34.2% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:pep phosphonomutase; PDBTitle: crystal structure of a putative phosphoenolpyruvate phosphonomutase2 (ncgl1015, cgl1060) from corynebacterium glutamicum atcc 13032 at3 1.80 a resolution Phyre2 PDB 2keb chain A Region: 316 - 352 Aligned: 37 Modelled: 37 Confidence: 31.3% Identity: 19% PDB header:dna binding protein Chain: A: PDB Molecule:dna polymerase subunit alpha b; PDBTitle: nmr solution structure of the n-terminal domain of the dna polymerase2 alpha p68 subunit Phyre2 PDB 2ze3 chain A Region: 14 - 120 Aligned: 91 Modelled: 106 Confidence: 30.4% Identity: 20% PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus Phyre2 PDB 3bzr chain A domain 1 Region: 162 - 201 Aligned: 40 Modelled: 40 Confidence: 28.4% Identity: 20% Fold: EscU C-terminal domain-like Superfamily: EscU C-terminal domain-like Family: EscU C-terminal domain-like Phyre2 PDB 3bzr chain A Region: 162 - 201 Aligned: 40 Modelled: 40 Confidence: 28.4% Identity: 20% PDB header:membrane protein, protein transport Chain: A: PDB Molecule:escu; PDBTitle: crystal structure of escu c-terminal domain with n262d mutation, space2 group p 41 21 2 Phyre2 PDB 1e0m chain A Region: 200 - 213 Aligned: 14 Modelled: 14 Confidence: 28.2% Identity: 36% PDB header:de novo protein Chain: A: PDB Molecule:wwprototype; PDBTitle: prototype ww domain Phyre2 1 c2g8yB_ 2 c3i0pA_ 3 c1z2iA_ 4 c1vbiA_ 5 d1rfma_ 6 d1xrha_ 7 c1wtjB_ 8 d1nxua_ 9 c1v9nA_ 10 c3uoeB_ 11 d1jmxa1 12 c3irvA_ 13 c3eefA_ 14 c3kl2K_ 15 c2qiwA_ 16 c2kebA_ 17 c2ze3A_ 18 d3bzra1 19 c3bzrA_ 20 c1e0mA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2g8yB_ 100.0 97 PDB header:oxidoreductase Chain: B: PDB Molecule:malate/l-lactate dehydrogenases; PDBTitle: the structure of a putative malate/lactate dehydrogenase from e. coli. 2 c3i0pA_ 100.0 26 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of malate dehydrogenase from entamoeba histolytica 3 c1z2iA_ 100.0 28 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of agrobacterium tumefaciens malate2 dehydrogenase, new york structural genomics consortium 4 c1vbiA_ 100.0 31 PDB header:oxidoreductase Chain: A: PDB Molecule:type 2 malate/lactate dehydrogenase; PDBTitle: crystal structure of type 2 malate/lactate dehydrogenase from thermus2 thermophilus hb8 5 d1rfma_ 100.0 32 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 6 d1xrha_ 100.0 28 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 7 c1wtjB_ 100.0 28 PDB header:oxidoreductase Chain: B: PDB Molecule:ureidoglycolate dehydrogenase; PDBTitle: crystal structure of delta1-piperideine-2-carboxylate2 reductase from pseudomonas syringae pvar.tomato 8 d1nxua_ 100.0 24 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 9 c1v9nA_ 100.0 32 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: structure of malate dehydrogenase from pyrococcus horikoshii ot3 10 c3uoeB_ 100.0 26 PDB header:oxidoreductase Chain: B: PDB Molecule:dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from sinorhizobium meliloti 11 d1jmxa1 40.9 14 Fold:Cytochrome c Superfamily:Cytochrome c Family:Quinohemoprotein amine dehydrogenase A chain, domains 1 and 2 12 c3irvA_ 38.1 9 PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a 13 c3eefA_ 34.6 22 PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum 14 c3kl2K_ 34.5 13 PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis 15 c2qiwA_ 34.2 15 PDB header:transferase Chain: A: PDB Molecule:pep phosphonomutase; PDBTitle: crystal structure of a putative phosphoenolpyruvate phosphonomutase2 (ncgl1015, cgl1060) from corynebacterium glutamicum atcc 13032 at3 1.80 a resolution 16 c2kebA_ 31.3 19 PDB header:dna binding protein Chain: A: PDB Molecule:dna polymerase subunit alpha b; PDBTitle: nmr solution structure of the n-terminal domain of the dna polymerase2 alpha p68 subunit 17 c2ze3A_ 30.4 20 PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus 18 d3bzra1 28.4 20 Fold:EscU C-terminal domain-like Superfamily:EscU C-terminal domain-like Family:EscU C-terminal domain-like 19 c3bzrA_ 28.4 20 PDB header:membrane protein, protein transport Chain: A: PDB Molecule:escu; PDBTitle: crystal structure of escu c-terminal domain with n262d mutation, space2 group p 41 21 2 20 c1e0mA_ 28.2 36 PDB header:de novo protein Chain: A: PDB Molecule:wwprototype; PDBTitle: prototype ww domain 21 c2k29A_ not modelled 27.8 12 PDB header:transcription Chain: A: PDB Molecule:antitoxin relb; PDBTitle: structure of the dbd domain of e. coli antitoxin relb 22 c1yiuA_ not modelled 27.3 50 PDB header:ligase Chain: A: PDB Molecule:itchy e3 ubiquitin protein ligase; PDBTitle: itch e3 ubiquitin ligase ww3 domain 23 c3b8iF_ not modelled 26.9 14 PDB header:lyase Chain: F: PDB Molecule:pa4872 oxaloacetate decarboxylase; PDBTitle: crystal structure of oxaloacetate decarboxylase from pseudomonas2 aeruginosa (pa4872) in complex with oxalate and mg2+. 24 c3ih1A_ not modelled 26.4 21 PDB header:lyase Chain: A: PDB Molecule:methylisocitrate lyase; PDBTitle: crystal structure of carboxyvinyl-carboxyphosphonate phosphorylmutase2 from bacillus anthracis 25 c3ot4F_ not modelled 26.2 20 PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf 26 c2b34C_ not modelled 25.9 13 PDB header:hydrolase Chain: C: PDB Molecule:mar1 ribonuclease; PDBTitle: structure of mar1 ribonuclease from caenorhabditis elegans 27 c2ysbA_ not modelled 25.9 29 PDB header:protein binding Chain: A: PDB Molecule:salvador homolog 1 protein; PDBTitle: solution structure of the first ww domain from the mouse2 salvador homolog 1 protein (sav1) 28 c2jlhA_ not modelled 25.7 23 PDB header:protein transport Chain: A: PDB Molecule:yop proteins translocation protein u; PDBTitle: crystal structure of the cytoplasmic domain of yersinia2 pestis yscu n263a mutant 29 c3l4hA_ not modelled 25.5 17 PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase hecw1; PDBTitle: helical box domain and second ww domain of the human e3 ubiquitin-2 protein ligase hecw1 30 d1nf9a_ not modelled 25.5 11 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 31 d2ebfx2 not modelled 25.5 16 Fold:EreA/ChaN-like Superfamily:EreA/ChaN-like Family:PMT domain-like 32 c3t7yB_ not modelled 24.9 23 PDB header:protein transport Chain: B: PDB Molecule:yop proteins translocation protein u; PDBTitle: structure of an autocleavage-inactive mutant of the cytoplasmic domain2 of ct091, the yscu homologue of chlamydia trachomatis 33 d1nbaa_ not modelled 24.8 20 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 34 d1vp8a_ not modelled 24.3 24 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 35 c1ymzA_ not modelled 24.1 50 PDB header:unknown function Chain: A: PDB Molecule:cc45; PDBTitle: cc45, an artificial ww domain designed using statistical2 coupling analysis 36 d1qusa_ not modelled 23.6 17 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:Bacterial muramidase, catalytic domain 37 d1t57a_ not modelled 23.2 23 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 38 c3mcwA_ not modelled 23.0 12 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution 39 c2ysdA_ not modelled 22.7 27 PDB header:protein binding Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz PDBTitle: solution structure of the first ww domain from the human2 membrane-associated guanylate kinase, ww and pdz domain-3 containing protein 1. magi-1 40 c3i44A_ not modelled 22.0 18 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from bartonella2 henselae at 2.0a resolution 41 d1yaca_ not modelled 21.5 8 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 42 d1j2ra_ not modelled 21.4 18 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 43 d1f8ab1 not modelled 21.3 27 Fold:WW domain-like Superfamily:WW domain Family:WW domain 44 c2djyA_ not modelled 21.0 36 PDB header:ligase/signaling protein Chain: A: PDB Molecule:smad ubiquitination regulatory factor 2; PDBTitle: solution structure of smurf2 ww3 domain-smad7 py peptide2 complex 45 c2hjpA_ not modelled 20.5 12 PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++ 46 d1wh7a_ not modelled 20.4 17 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Homeodomain 47 d1k9ra_ not modelled 20.0 29 Fold:WW domain-like Superfamily:WW domain Family:WW domain 48 c1wr7A_ not modelled 20.0 47 PDB header:ligase Chain: A: PDB Molecule:nedd4-2; PDBTitle: solution structure of the third ww domain of nedd4-2 49 c3hb7G_ not modelled 19.9 13 PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a 50 d1pbya1 not modelled 19.8 17 Fold:Cytochrome c Superfamily:Cytochrome c Family:Quinohemoprotein amine dehydrogenase A chain, domains 1 and 2 51 c2lawA_ not modelled 19.5 29 PDB header:signaling protein/transcription Chain: A: PDB Molecule:yorkie homolog; PDBTitle: structure of the second ww domain from human yap in complex with a2 human smad1 derived peptide 52 d1lqaa_ not modelled 19.4 13 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 53 c2gbbA_ not modelled 19.2 11 PDB header:isomerase Chain: A: PDB Molecule:putative chorismate mutase; PDBTitle: crystal structure of secreted chorismate mutase from2 yersinia pestis 54 c1wr4A_ not modelled 19.0 29 PDB header:ligase Chain: A: PDB Molecule:ubiquitin-protein ligase nedd4-2; PDBTitle: solution structure of the second ww domain of nedd4-2 55 c2kykA_ not modelled 18.9 43 PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog; PDBTitle: the sandwich region between two lmp2a py motif regulates the2 interaction between aip4ww2domain and py motif 56 d3ci0k2 not modelled 18.5 19 Fold:SAM domain-like Superfamily:GspK insert domain-like Family:GspK insert domain-like 57 c3iwfA_ not modelled 18.2 9 PDB header:transcription regulator Chain: A: PDB Molecule:transcription regulator rpir family; PDBTitle: the crystal structure of the n-terminal domain of a rpir2 transcriptional regulator from staphylococcus epidermidis to 1.4a 58 c2jmfA_ not modelled 18.2 33 PDB header:ligase/signaling protein Chain: A: PDB Molecule:e3 ubiquitin-protein ligase suppressor of deltex; PDBTitle: solution structure of the su(dx) ww4- notch py peptide2 complex 59 c1wmvA_ not modelled 18.2 28 PDB header:oxidoreductase, apoptosis Chain: A: PDB Molecule:ww domain containing oxidoreductase; PDBTitle: solution structure of the second ww domain of wwox 60 c2p7vA_ not modelled 17.9 29 PDB header:transcription Chain: A: PDB Molecule:regulator of sigma d; PDBTitle: crystal structure of the escherichia coli regulator of sigma 70, rsd,2 in complex with sigma 70 domain 4 61 d1tk7a1 not modelled 17.8 29 Fold:WW domain-like Superfamily:WW domain Family:WW domain 62 c2pmzF_ not modelled 17.6 20 PDB header:translation, transferase Chain: F: PDB Molecule:dna-directed rna polymerase subunit f; PDBTitle: archaeal rna polymerase from sulfolobus solfataricus 63 d1i5hw_ not modelled 17.0 36 Fold:WW domain-like Superfamily:WW domain Family:WW domain 64 d2jmfa1 not modelled 16.8 36 Fold:WW domain-like Superfamily:WW domain Family:WW domain 65 d1bdga1 not modelled 16.6 17 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Hexokinase 66 c2uygF_ not modelled 16.0 24 PDB header:lyase Chain: F: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystallogaphic structure of the typeii 3-dehydroquinase2 from thermus thermophilus 67 c1zlpA_ not modelled 15.9 22 PDB header:lyase Chain: A: PDB Molecule:petal death protein; PDBTitle: petal death protein psr132 with cysteine-linked glutaraldehyde forming2 a thiohemiacetal adduct 68 c3e0kA_ not modelled 15.9 13 PDB header:transferase Chain: A: PDB Molecule:amino-acid acetyltransferase; PDBTitle: crystal structure of c-termianl domain of n-acetylglutamate synthase2 from vibrio parahaemolyticus 69 d2cfua2 not modelled 15.5 17 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Alkylsulfatase-like 70 c3eooL_ not modelled 15.1 19 PDB header:lyase Chain: L: PDB Molecule:methylisocitrate lyase; PDBTitle: 2.9a crystal structure of methyl-isocitrate lyase from2 burkholderia pseudomallei 71 c2ez5W_ not modelled 14.9 33 PDB header:signalling protein,ligase Chain: W: PDB Molecule:e3 ubiquitin-protein ligase nedd4; PDBTitle: solution structure of the dnedd4 ww3* domain- comm lpsy2 peptide complex 72 c2js5B_ not modelled 14.8 26 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: nmr structure of protein q60c73_metca. northeast structural2 genomics consortium target mcr1 73 c3hn2A_ not modelled 14.2 11 PDB header:oxidoreductase Chain: A: PDB Molecule:2-dehydropantoate 2-reductase; PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from geobacter2 metallireducens gs-15 74 c2yshA_ not modelled 14.1 27 PDB header:protein binding Chain: A: PDB Molecule:growth-arrest-specific protein 7; PDBTitle: solution structure of the ww domain from the human growth-2 arrest-specific protein 7, gas-7 75 c2yy9A_ not modelled 14.0 31 PDB header:transcription Chain: A: PDB Molecule:zinc finger and btb domain-containing protein 48; PDBTitle: crystal structure of btb domain from mouse hkr3 76 d2csua3 not modelled 14.0 17 Fold:Flavodoxin-like Superfamily:Succinyl-CoA synthetase domains Family:Succinyl-CoA synthetase domains 77 c2q81C_ not modelled 13.6 19 PDB header:transcription Chain: C: PDB Molecule:miz-1 protein; PDBTitle: crystal structure of the miz-1 btb/poz domain 78 c3fa4D_ not modelled 13.6 20 PDB header:lyase Chain: D: PDB Molecule:2,3-dimethylmalate lyase; PDBTitle: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate2 lyase superfamily member, triclinic crystal form 79 d3djba1 not modelled 13.5 17 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 80 d1xn7a_ not modelled 13.1 24 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Hypothetical protein YhgG 81 d1dq3a2 not modelled 13.1 32 Fold:dsRBD-like Superfamily:YcfA/nrd intein domain Family:PI-Pfui intein middle domain 82 c3le4A_ not modelled 12.9 33 PDB header:nuclear protein Chain: A: PDB Molecule:microprocessor complex subunit dgcr8; PDBTitle: crystal structure of the dgcr8 dimerization domain 83 c1ks9A_ not modelled 12.8 11 PDB header:oxidoreductase Chain: A: PDB Molecule:2-dehydropantoate 2-reductase; PDBTitle: ketopantoate reductase from escherichia coli 84 d1j9ia_ not modelled 12.8 25 Fold:Putative DNA-binding domain Superfamily:Putative DNA-binding domain Family:Terminase gpNU1 subunit domain 85 c2r73C_ not modelled 12.7 13 PDB header:transport protein Chain: C: PDB Molecule:trichosurin; PDBTitle: crystal structure of the possum milk whey lipocalin2 trichosurin at ph 8.2 86 c2l4jA_ not modelled 12.5 33 PDB header:transcription Chain: A: PDB Molecule:yes-associated protein 2 (yap2); PDBTitle: yap ww2 87 d2ieca1 not modelled 12.5 17 Fold:MK0786-like Superfamily:MK0786-like Family:MK0786-like 88 d1dzka_ not modelled 12.3 23 Fold:Lipocalins Superfamily:Lipocalins Family:Retinol binding protein-like 89 c2jt1A_ not modelled 12.2 21 PDB header:transcription Chain: A: PDB Molecule:pefi protein; PDBTitle: solution nmr structure of pefi (plasmid-encoded fimbriae regulatory)2 protein from salmonella typhimurium. northeast structural genomics3 target str82 90 c2h0rD_ not modelled 12.2 12 PDB header:hydrolase Chain: D: PDB Molecule:nicotinamidase; PDBTitle: structure of the yeast nicotinamidase pnc1p 91 c3fiqA_ not modelled 12.1 21 PDB header:transport protein Chain: A: PDB Molecule:odorant-binding protein 1f; PDBTitle: odorant binding protein obp1 92 c2px0D_ not modelled 12.1 11 PDB header:biosynthetic protein Chain: D: PDB Molecule:flagellar biosynthesis protein flhf; PDBTitle: crystal structure of flhf complexed with gmppnp/mg(2+) 93 c2lfcA_ not modelled 11.9 29 PDB header:oxidoreductase Chain: A: PDB Molecule:fumarate reductase, flavoprotein subunit; PDBTitle: solution nmr structure of fumarate reductase flavoprotein subunit from2 lactobacillus plantarum, northeast structural genomics consortium3 target lpr145j 94 c3drzE_ not modelled 11.9 13 PDB header:unknown function Chain: E: PDB Molecule:btb/poz domain-containing protein kctd5; PDBTitle: x-ray crystal structure of the n-terminal btb domain of human kctd52 protein 95 c3fpvC_ not modelled 11.9 21 PDB header:heme binding protein Chain: C: PDB Molecule:extracellular haem-binding protein; PDBTitle: crystal structure of hbps 96 d2i52a1 not modelled 11.6 17 Fold:MK0786-like Superfamily:MK0786-like Family:MK0786-like 97 d1bj7a_ not modelled 11.4 13 Fold:Lipocalins Superfamily:Lipocalins Family:Retinol binding protein-like 98 c2fq1A_ not modelled 11.4 15 PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains 99 c2lazA_ not modelled 11.4 29 PDB header:signaling protein/transcription Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1; PDBTitle: structure of the first ww domain of human smurf1 in complex with a2 mono-phosphorylated human smad1 derived peptide

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0