Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP39381
DateThu Jan 5 12:00:13 GMT 2012
Unique Job ID731affe7b0c8820e

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1pw4a_
Top template information
Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:Glycerol-3-phosphate transporter
Confidence and coverage
Confidence:100.0% Coverage: 98%
385 residues ( 98% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MPSSTHPVERFSFSTALFGMLVLTLGMGLGRFLYTPMLPVMMAEGSFSFSQLSWIASGNY
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   .........70.........80.........90.........100.........110.........120
Sequence  AGYLAGSLLFSFGAFHQPSRLRPFLLASALASGLLILAMAWLPPFILVLLIRVLAGVASA
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   .........130.........140.........150.........160.........170.........180
Sequence  GMLIFGSTLIMQHTRHPFVLAALFSGVGIGIALGNEYVLAGLHFDLSSQTLWQGAGALSG
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   .........190.........200.........210.........220.........230.........240
Sequence  MMLIALTLLMPSKKHAITPMPLAKTEQQIMSWWLLAILYGLAGFGYIIVATYLPLMAKDA
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?

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   .........250.........260.........270.........280.........290.........300
Sequence  GSPLLTAHLWTLVGLSIVPGCFGWLWAAKRWGALPCLTANLLVQAICVLLTLASDSPLLL
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   .........310.........320.........330.........340.........350.........360
Sequence  IISSLGFGGTFMGTTSLVMTIARQLSVPGNLNLLGFVTLIYGIGQILGPALTSMLSNGTS
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   .........370.........380.........390..
Sequence  ALASATLCGAAALFIAALISTVQLFKLQVVTS
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?????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1pw4 chain A

3D model

Region: 1 - 388
Aligned: 385
Modelled: 388
Confidence: 100.0%
Identity: 12%
Fold: MFS general substrate transporter
Superfamily: MFS general substrate transporter
Family: Glycerol-3-phosphate transporter

Phyre2

PDB 1pv7 chain A

3D model

Region: 9 - 391
Aligned: 378
Modelled: 383
Confidence: 100.0%
Identity: 13%
Fold: MFS general substrate transporter
Superfamily: MFS general substrate transporter
Family: LacY-like proton/sugar symporter

Phyre2

PDB 2gfp chain A

3D model

Region: 17 - 375
Aligned: 359
Modelled: 359
Confidence: 100.0%
Identity: 12%
PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein d;
PDBTitle: structure of the multidrug transporter emrd from2 escherichia coli

Phyre2

PDB 3o7p chain A

3D model

Region: 11 - 387
Aligned: 371
Modelled: 377
Confidence: 100.0%
Identity: 12%
PDB header:transport protein
Chain: A: PDB Molecule:l-fucose-proton symporter;
PDBTitle: crystal structure of the e.coli fucose:proton symporter, fucp (n162a)

Phyre2

PDB 2xut chain C

3D model

Region: 13 - 382
Aligned: 365
Modelled: 370
Confidence: 99.9%
Identity: 10%
PDB header:transport protein
Chain: C: PDB Molecule:proton/peptide symporter family protein;
PDBTitle: crystal structure of a proton dependent oligopeptide (pot)2 family transporter.

Phyre2

PDB 3pro chain C domain 1

3D model

Region: 37 - 52
Aligned: 16
Modelled: 16
Confidence: 21.4%
Identity: 19%
Fold: Alpha-lytic protease prodomain-like
Superfamily: Alpha-lytic protease prodomain
Family: Alpha-lytic protease prodomain

Phyre2

PDB 2xq2 chain A

3D model

Region: 75 - 212
Aligned: 132
Modelled: 138
Confidence: 9.3%
Identity: 10%
PDB header:transport protein
Chain: A: PDB Molecule:sodium/glucose cotransporter;
PDBTitle: structure of the k294a mutant of vsglt

Phyre2

PDB 3qnq chain D

3D model

Region: 146 - 208
Aligned: 63
Modelled: 63
Confidence: 7.0%
Identity: 10%
PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system

Phyre2
1

d1pw4a_
2

d1pv7a_
3

c2gfpA_
4

c3o7pA_
5

c2xutC_
6

d3proc1
7

c2xq2A_
8

c3qnqD_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1pw4a_



100.0 12 Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:Glycerol-3-phosphate transporter
2d1pv7a_



100.0 13 Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:LacY-like proton/sugar symporter
3c2gfpA_



100.0 12 PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein d;
PDBTitle: structure of the multidrug transporter emrd from2 escherichia coli
4c3o7pA_



100.0 12 PDB header:transport protein
Chain: A: PDB Molecule:l-fucose-proton symporter;
PDBTitle: crystal structure of the e.coli fucose:proton symporter, fucp (n162a)
5c2xutC_



99.9 10 PDB header:transport protein
Chain: C: PDB Molecule:proton/peptide symporter family protein;
PDBTitle: crystal structure of a proton dependent oligopeptide (pot)2 family transporter.
6d3proc1



21.4 19 Fold:Alpha-lytic protease prodomain-like
Superfamily:Alpha-lytic protease prodomain
Family:Alpha-lytic protease prodomain
7c2xq2A_



9.3 10 PDB header:transport protein
Chain: A: PDB Molecule:sodium/glucose cotransporter;
PDBTitle: structure of the k294a mutant of vsglt
8c3qnqD_



7.0 10 PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0