Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	T	L	N	R	R	D	F	P	G	A	Q	Y	P	E	R	I	I	Q	F	G	E	G	N	F	L	R	A	F	V	D	W	Q	I	D	L	L	N	E	H	T	D	L	N	S	G	V	V	V	V	R	P	I	E	T	S	F	P	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	L	S	T	Q	D	G	L	Y	T	T	I	I	R	G	L	N	E	K	G	E	A	V	S	D	A	R	L	I	R	S	V	N	R	E	I	S	V	Y	S	E	Y	D	E	F	L	K	L	A	H	N	P	E	M	R	F	V	F	S	N
Secondary structure
SS confidence
Disorder																		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	T	E	A	G	I	S	Y	H	A	G	D	K	F	D	D	A	P	A	V	S	Y	P	A	K	L	T	R	L	L	F	E	R	F	S	H	F	N	G	A	L	D	K	G	W	I	I	I	P	C	E	L	I	D	Y	N	G	D	A	L
Secondary structure
SS confidence
Disorder																																								?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	E	L	V	L	R	Y	A	Q	E	W	A	L	P	E	A	F	I	Q	W	L	D	Q	A	N	S	F	C	S	T	L	V	D	R	I	V	T	G	Y	P	R	D	E	V	A	K	L	E	E	E	L	G	Y	H	D	G	F	L	D	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	E	H	F	Y	L	F	V	I	Q	G	P	K	S	L	A	T	E	L	R	L	D	K	Y	P	L	N	V	L	I	V	D	D	I	K	P	Y	K	E	R	K	V	A	I	L	N	G	A	H	T	A	L	V	P	V	A	F	Q	A	G
Secondary structure
SS confidence
Disorder															?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	D	T	V	G	E	A	M	N	D	A	E	I	C	A	F	V	E	K	A	I	Y	E	E	I	I	P	V	L	D	L	P	R	D	E	L	E	S	F	A	S	A	V	T	G	R	F	R	N	P	Y	I	K	H	Q	L	L	S	I	A
Secondary structure
SS confidence
Disorder																																																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		L	N	G	M	T	K	F	R	T	R	I	L	P	Q	L	L	A	G	Q	K	A	N	G	T	L	P	A	R	L	T	F	A	L	A	A	L	I	A	F	Y	R	G	E	R	N	G	E	T	Y	P	V	Q	D	D	A	H	W	L	E	R
Secondary structure
SS confidence
Disorder		?	?					?	?																																					?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		Y	Q	Q	L	W	S	Q	H	R	D	R	V	I	G	T	Q	E	L	V	A	I	V	L	A	E	K	D	H	W	E	Q	D	L	T	Q	V	P	G	L	V	E	Q	V	A	N	D	L	D	A	I	L	E	K	G	M	R	E	A	V	R
Secondary structure
SS confidence
Disorder								?		?	?	?	?	?
Disorder confidence
		.	.	.
Sequence		P	L	C
Secondary structure
SS confidence
Disorder			?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1m2w chain A Region: 2 - 482 Aligned: 462 Modelled: 481 Confidence: 100.0% Identity: 23% PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol dehydrogenase; PDBTitle: pseudomonas fluorescens mannitol 2-dehydrogenase ternary complex with2 nad and d-mannitol Phyre2 PDB 3h2z chain A Region: 16 - 470 Aligned: 370 Modelled: 421 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol-1-phosphate 5-dehydrogenase; PDBTitle: the crystal structure of mannitol-1-phosphate dehydrogenase from2 shigella flexneri Phyre2 PDB 1lj8 chain A domain 4 Region: 3 - 272 Aligned: 261 Modelled: 270 Confidence: 100.0% Identity: 21% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain Phyre2 PDB 1lj8 chain A domain 3 Region: 273 - 483 Aligned: 201 Modelled: 211 Confidence: 100.0% Identity: 25% Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like Family: Mannitol 2-dehydrogenase Phyre2 PDB 2ph5 chain A Region: 8 - 194 Aligned: 164 Modelled: 171 Confidence: 88.1% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:homospermidine synthase; PDBTitle: crystal structure of the homospermidine synthase hss from legionella2 pneumophila in complex with nad, northeast structural genomics target3 lgr54 Phyre2 PDB 3cea chain A Region: 12 - 121 Aligned: 75 Modelled: 83 Confidence: 87.8% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:myo-inositol 2-dehydrogenase; PDBTitle: crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from2 lactobacillus plantarum at 2.40 a resolution Phyre2 PDB 3mtj chain A Region: 11 - 120 Aligned: 102 Modelled: 107 Confidence: 83.1% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:homoserine dehydrogenase; PDBTitle: the crystal structure of a homoserine dehydrogenase from thiobacillus2 denitrificans to 2.15a Phyre2 PDB 3c7c chain B Region: 17 - 174 Aligned: 138 Modelled: 152 Confidence: 78.2% Identity: 12% PDB header:oxidoreductase Chain: B: PDB Molecule:octopine dehydrogenase; PDBTitle: a structural basis for substrate and stereo selectivity in2 octopine dehydrogenase (odh-nadh-l-arginine) Phyre2 PDB 3euw chain B Region: 14 - 184 Aligned: 134 Modelled: 151 Confidence: 77.2% Identity: 17% PDB header:oxidoreductase Chain: B: PDB Molecule:myo-inositol dehydrogenase; PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032 Phyre2 PDB 2axq chain A Region: 17 - 122 Aligned: 73 Modelled: 83 Confidence: 66.6% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine dehydrogenase; PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae Phyre2 PDB 3q2k chain B Region: 14 - 67 Aligned: 49 Modelled: 54 Confidence: 65.3% Identity: 10% PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of the wlba dehydrogenase from bordetella pertussis2 in complex with nadh and udp-glcnaca Phyre2 PDB 3ket chain A Region: 13 - 121 Aligned: 75 Modelled: 80 Confidence: 64.7% Identity: 15% PDB header:transcription/dna Chain: A: PDB Molecule:redox-sensing transcriptional repressor rex; PDBTitle: crystal structure of a rex-family transcriptional regulatory protein2 from streptococcus agalactiae bound to a palindromic operator Phyre2 PDB 3e18 chain A Region: 15 - 122 Aligned: 70 Modelled: 79 Confidence: 60.1% Identity: 23% PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of nad-binding protein from listeria innocua Phyre2 PDB 2q4e chain B Region: 15 - 193 Aligned: 118 Modelled: 135 Confidence: 60.0% Identity: 17% PDB header:oxidoreductase Chain: B: PDB Molecule:probable oxidoreductase at4g09670; PDBTitle: ensemble refinement of the protein crystal structure of gene product2 from arabidopsis thaliana at4g09670 Phyre2 PDB 1e5l chain A Region: 17 - 120 Aligned: 95 Modelled: 104 Confidence: 58.1% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine reductase; PDBTitle: apo saccharopine reductase from magnaporthe grisea Phyre2 PDB 3fd8 chain A Region: 14 - 121 Aligned: 73 Modelled: 81 Confidence: 57.9% Identity: 10% PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis Phyre2 PDB 3moi chain A Region: 14 - 121 Aligned: 72 Modelled: 80 Confidence: 55.4% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:probable dehydrogenase; PDBTitle: the crystal structure of the putative dehydrogenase from bordetella2 bronchiseptica rb50 Phyre2 PDB 3c1a chain B Region: 15 - 70 Aligned: 50 Modelled: 56 Confidence: 50.5% Identity: 10% PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase (zp_00056571.1) from2 magnetospirillum magnetotacticum ms-1 at 1.85 a resolution Phyre2 PDB 3db2 chain C Region: 15 - 65 Aligned: 45 Modelled: 51 Confidence: 48.6% Identity: 11% PDB header:oxidoreductase Chain: C: PDB Molecule:putative nadph-dependent oxidoreductase; PDBTitle: crystal structure of a putative nadph-dependent oxidoreductase2 (dhaf_2064) from desulfitobacterium hafniense dcb-2 at 1.70 a3 resolution Phyre2 PDB 1ofg chain F Region: 12 - 65 Aligned: 49 Modelled: 54 Confidence: 45.8% Identity: 6% PDB header:oxidoreductase Chain: F: PDB Molecule:glucose-fructose oxidoreductase; PDBTitle: glucose-fructose oxidoreductase Phyre2 1 c1m2wA_ 2 c3h2zA_ 3 d1lj8a4 4 d1lj8a3 5 c2ph5A_ 6 c3ceaA_ 7 c3mtjA_ 8 c3c7cB_ 9 c3euwB_ 10 c2axqA_ 11 c3q2kB_ 12 c3ketA_ 13 c3e18A_ 14 c2q4eB_ 15 c1e5lA_ 16 c3fd8A_ 17 c3moiA_ 18 c3c1aB_ 19 c3db2C_ 20 c1ofgF_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1m2wA_ 100.0 23 PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol dehydrogenase; PDBTitle: pseudomonas fluorescens mannitol 2-dehydrogenase ternary complex with2 nad and d-mannitol 2 c3h2zA_ 100.0 22 PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol-1-phosphate 5-dehydrogenase; PDBTitle: the crystal structure of mannitol-1-phosphate dehydrogenase from2 shigella flexneri 3 d1lj8a4 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 4 d1lj8a3 100.0 25 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like Family:Mannitol 2-dehydrogenase 5 c2ph5A_ 88.1 13 PDB header:transferase Chain: A: PDB Molecule:homospermidine synthase; PDBTitle: crystal structure of the homospermidine synthase hss from legionella2 pneumophila in complex with nad, northeast structural genomics target3 lgr54 6 c3ceaA_ 87.8 16 PDB header:oxidoreductase Chain: A: PDB Molecule:myo-inositol 2-dehydrogenase; PDBTitle: crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from2 lactobacillus plantarum at 2.40 a resolution 7 c3mtjA_ 83.1 18 PDB header:oxidoreductase Chain: A: PDB Molecule:homoserine dehydrogenase; PDBTitle: the crystal structure of a homoserine dehydrogenase from thiobacillus2 denitrificans to 2.15a 8 c3c7cB_ 78.2 12 PDB header:oxidoreductase Chain: B: PDB Molecule:octopine dehydrogenase; PDBTitle: a structural basis for substrate and stereo selectivity in2 octopine dehydrogenase (odh-nadh-l-arginine) 9 c3euwB_ 77.2 17 PDB header:oxidoreductase Chain: B: PDB Molecule:myo-inositol dehydrogenase; PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032 10 c2axqA_ 66.6 21 PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine dehydrogenase; PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae 11 c3q2kB_ 65.3 10 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of the wlba dehydrogenase from bordetella pertussis2 in complex with nadh and udp-glcnaca 12 c3ketA_ 64.7 15 PDB header:transcription/dna Chain: A: PDB Molecule:redox-sensing transcriptional repressor rex; PDBTitle: crystal structure of a rex-family transcriptional regulatory protein2 from streptococcus agalactiae bound to a palindromic operator 13 c3e18A_ 60.1 23 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of nad-binding protein from listeria innocua 14 c2q4eB_ 60.0 17 PDB header:oxidoreductase Chain: B: PDB Molecule:probable oxidoreductase at4g09670; PDBTitle: ensemble refinement of the protein crystal structure of gene product2 from arabidopsis thaliana at4g09670 15 c1e5lA_ 58.1 18 PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine reductase; PDBTitle: apo saccharopine reductase from magnaporthe grisea 16 c3fd8A_ 57.9 10 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis 17 c3moiA_ 55.4 17 PDB header:oxidoreductase Chain: A: PDB Molecule:probable dehydrogenase; PDBTitle: the crystal structure of the putative dehydrogenase from bordetella2 bronchiseptica rb50 18 c3c1aB_ 50.5 10 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase (zp_00056571.1) from2 magnetospirillum magnetotacticum ms-1 at 1.85 a resolution 19 c3db2C_ 48.6 11 PDB header:oxidoreductase Chain: C: PDB Molecule:putative nadph-dependent oxidoreductase; PDBTitle: crystal structure of a putative nadph-dependent oxidoreductase2 (dhaf_2064) from desulfitobacterium hafniense dcb-2 at 1.70 a3 resolution 20 c1ofgF_ 45.8 6 PDB header:oxidoreductase Chain: F: PDB Molecule:glucose-fructose oxidoreductase; PDBTitle: glucose-fructose oxidoreductase 21 c1evjC_ not modelled 45.4 6 PDB header:oxidoreductase Chain: C: PDB Molecule:glucose-fructose oxidoreductase; PDBTitle: crystal structure of glucose-fructose oxidoreductase (gfor)2 delta1-22 s64d 22 c1zh8B_ not modelled 41.1 15 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of oxidoreductase (tm0312) from thermotoga maritima2 at 2.50 a resolution 23 c1h6dL_ not modelled 40.8 8 PDB header:protein translocation Chain: L: PDB Molecule:precursor form of glucose-fructose PDBTitle: oxidized precursor form of glucose-fructose oxidoreductase2 from zymomonas mobilis complexed with glycerol 24 c3ezyB_ not modelled 39.5 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:dehydrogenase; PDBTitle: crystal structure of probable dehydrogenase tm_0414 from2 thermotoga maritima 25 c3nt5B_ not modelled 38.6 16 PDB header:oxidoreductase Chain: B: PDB Molecule:inositol 2-dehydrogenase/d-chiro-inositol 3-dehydrogenase; PDBTitle: crystal structure of myo-inositol dehydrogenase from bacillus subtilis2 with bound cofactor and product inosose 26 d1q0qa2 not modelled 38.3 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 27 d2nvwa1 not modelled 38.2 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 28 d1zh8a1 not modelled 37.7 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 29 d1ydwa1 not modelled 36.3 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 30 d1k4ia_ not modelled 36.3 20 Fold:YrdC/RibB Superfamily:YrdC/RibB Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB 31 d1gzsb_ not modelled 34.9 18 Fold:SopE-like GEF domain Superfamily:SopE-like GEF domain Family:SopE-like GEF domain 32 c2ixaA_ not modelled 30.5 12 PDB header:hydrolase Chain: A: PDB Molecule:alpha-n-acetylgalactosaminidase; PDBTitle: a-zyme, n-acetylgalactosaminidase 33 c3rbvA_ not modelled 29.8 13 PDB header:sugar binding protein Chain: A: PDB Molecule:sugar 3-ketoreductase; PDBTitle: crystal structure of kijd10, a 3-ketoreductase from actinomadura2 kijaniata incomplex with nadp 34 d1snna_ not modelled 29.2 29 Fold:YrdC/RibB Superfamily:YrdC/RibB Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB 35 d2dt5a2 not modelled 27.9 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Transcriptional repressor Rex, C-terminal domain 36 c1z9bA_ not modelled 27.8 11 PDB header:translation Chain: A: PDB Molecule:translation initiation factor if-2; PDBTitle: solution structure of the c1-subdomain of bacillus2 stearothermophilus translation initiation factor if2 37 c3mioA_ not modelled 27.4 22 PDB header:lyase Chain: A: PDB Molecule:3,4-dihydroxy-2-butanone 4-phosphate synthase; PDBTitle: crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase2 domain from mycobacterium tuberculosis at ph 6.00 38 c3e9mC_ not modelled 25.8 9 PDB header:oxidoreductase Chain: C: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis 39 c2dt5A_ not modelled 24.6 13 PDB header:dna binding protein Chain: A: PDB Molecule:at-rich dna-binding protein; PDBTitle: crystal structure of ttha1657 (at-rich dna-binding protein) from2 thermus thermophilus hb8 40 c1r0lD_ not modelled 23.9 14 PDB header:oxidoreductase Chain: D: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase; PDBTitle: 1-deoxy-d-xylulose 5-phosphate reductoisomerase from2 zymomonas mobilis in complex with nadph 41 d1f06a1 not modelled 23.7 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 42 c3dapB_ not modelled 23.3 19 PDB header:oxidoreductase Chain: B: PDB Molecule:diaminopimelic acid dehydrogenase; PDBTitle: c. glutamicum dap dehydrogenase in complex with nadp+ and2 the inhibitor 5s-isoxazoline 43 c2eghA_ not modelled 22.4 13 PDB header:oxidoreductase Chain: A: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase; PDBTitle: crystal structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase2 complexed with a magnesium ion, nadph and fosmidomycin 44 d2o8ra3 not modelled 22.3 33 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 45 d1yqga2 not modelled 21.1 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 46 c3kuxA_ not modelled 21.1 19 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: structure of the ypo2259 putative oxidoreductase from yersinia pestis 47 c2glxD_ not modelled 20.6 20 PDB header:oxidoreductase Chain: D: PDB Molecule:1,5-anhydro-d-fructose reductase; PDBTitle: crystal structure analysis of bacterial 1,5-af reductase 48 c3ff6D_ not modelled 20.5 16 PDB header:ligase Chain: D: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: human acc2 ct domain with cp-640186 49 c2ho3D_ not modelled 18.8 8 PDB header:oxidoreductase Chain: D: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of oxidoreductase, gfo/idh/moca family from2 streptococcus pneumoniae 50 c2nvwB_ not modelled 18.3 13 PDB header:transcription Chain: B: PDB Molecule:galactose/lactose metabolism regulatory protein PDBTitle: crystal sctucture of transcriptional regulator gal80p from2 kluyveromymes lactis 51 c2o48X_ not modelled 16.8 17 PDB header:oxidoreductase Chain: X: PDB Molecule:dimeric dihydrodiol dehydrogenase; PDBTitle: crystal structure of mammalian dimeric dihydrodiol dehydrogenase 52 c3ec7C_ not modelled 15.7 15 PDB header:oxidoreductase Chain: C: PDB Molecule:putative dehydrogenase; PDBTitle: crystal structure of putative dehydrogenase from salmonella2 typhimurium lt2 53 c3uuwB_ not modelled 15.7 11 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase with nad(p)-binding rossmann-fold PDBTitle: 1.63 angstrom resolution crystal structure of dehydrogenase (mvim)2 from clostridium difficile. 54 c3updA_ not modelled 15.0 12 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: 2.9 angstrom crystal structure of ornithine carbamoyltransferase2 (argf) from vibrio vulnificus 55 d1v29a_ not modelled 14.4 33 Fold:Nitrile hydratase alpha chain Superfamily:Nitrile hydratase alpha chain Family:Nitrile hydratase alpha chain 56 c1ceuA_ not modelled 14.1 11 PDB header:viral protein Chain: A: PDB Molecule:protein (hiv-1 regulatory protein n-terminal PDBTitle: nmr structure of the (1-51) n-terminal domain of the hiv-12 regulatory protein 57 d1im8a_ not modelled 13.9 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Hypothetical protein HI0319 (YecO) 58 d1ebfa1 not modelled 13.8 24 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 59 d1tlta1 not modelled 13.6 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 60 c2ejwB_ not modelled 13.6 14 PDB header:oxidoreductase Chain: B: PDB Molecule:homoserine dehydrogenase; PDBTitle: homoserine dehydrogenase from thermus thermophilus hb8 61 c3qyhG_ not modelled 13.2 29 PDB header:lyase Chain: G: PDB Molecule:co-type nitrile hydratase alpha subunit; PDBTitle: crystal structure of co-type nitrile hydratase beta-h71l from2 pseudomonas putida. 62 d2v0fa1 not modelled 13.1 33 Fold:GYF/BRK domain-like Superfamily:BRK domain-like Family:BRK domain-like 63 d1ugpa_ not modelled 13.0 21 Fold:Nitrile hydratase alpha chain Superfamily:Nitrile hydratase alpha chain Family:Nitrile hydratase alpha chain 64 c3v5nA_ not modelled 13.0 19 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase; PDBTitle: the crystal structure of oxidoreductase from sinorhizobium meliloti 65 c3eywA_ not modelled 12.0 18 PDB header:transport protein Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff 66 c3btuD_ not modelled 11.9 10 PDB header:transcription Chain: D: PDB Molecule:galactose/lactose metabolism regulatory protein PDBTitle: crystal structure of the super-repressor mutant of gal80p2 from saccharomyces cerevisiae; gal80(s2) [e351k] 67 c3e82A_ not modelled 11.8 12 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase from2 klebsiella pneumoniae 68 c3m2tA_ not modelled 11.8 11 PDB header:oxidoreductase Chain: A: PDB Molecule:probable dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from chromobacterium2 violaceum 69 d2qdya1 not modelled 11.6 38 Fold:Nitrile hydratase alpha chain Superfamily:Nitrile hydratase alpha chain Family:Nitrile hydratase alpha chain 70 d1p32a_ not modelled 11.4 14 Fold:Mitochondrial glycoprotein MAM33-like Superfamily:Mitochondrial glycoprotein MAM33-like Family:Mitochondrial glycoprotein MAM33-like 71 d2py6a1 not modelled 11.2 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:FkbM-like 72 c3qv0A_ not modelled 11.2 15 PDB header:protein binding Chain: A: PDB Molecule:mitochondrial acidic protein mam33; PDBTitle: crystal structure of saccharomyces cerevisiae mam33 73 c3ogiC_ not modelled 10.6 26 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:putative esat-6-like protein 6; PDBTitle: crystal structure of the mycobacterium tuberculosis h37rv esxop2 complex (rv2346c-rv2347c) 74 c3tsuA_ not modelled 10.6 5 PDB header:transferase Chain: A: PDB Molecule:transcriptional regulatory protein; PDBTitle: crystal structure of e. coli hypf with amp-pnp and carbamoyl phosphate 75 d2atca2 not modelled 10.6 26 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 76 c3gcgB_ not modelled 10.5 21 PDB header:signaling protein/transcription Chain: B: PDB Molecule:l0028 (mitochondria associated protein); PDBTitle: crystal structure of map and cdc42 complex 77 c3ingA_ not modelled 10.2 26 PDB header:oxidoreductase Chain: A: PDB Molecule:homoserine dehydrogenase; PDBTitle: crystal structure of homoserine dehydrogenase (np_394635.1) from2 thermoplasma acidophilum at 1.95 a resolution 78 c3fggA_ not modelled 10.2 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein bce2196; PDBTitle: crystal structure of putative ecf-type sigma factor negative effector2 from bacillus cereus 79 d1ekxa2 not modelled 10.0 20 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 80 c3guzB_ not modelled 9.5 18 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: structural and substrate-binding studies of pantothenate2 synthenate (ps)provide insights into homotropic inhibition3 by pantoate in ps's 81 c1iq5B_ not modelled 9.4 57 PDB header:metal binding protein/protein binding Chain: B: PDB Molecule:ca2+/calmodulin dependent kinase kinase; PDBTitle: calmodulin/nematode ca2+/calmodulin dependent kinase kinase2 fragment 82 d1hcia1 not modelled 9.2 19 Fold:Spectrin repeat-like Superfamily:Spectrin repeat Family:Spectrin repeat 83 d1yqfa1 not modelled 9.0 15 Fold:Mitochondrial glycoprotein MAM33-like Superfamily:Mitochondrial glycoprotein MAM33-like Family:Mitochondrial glycoprotein MAM33-like 84 c3jv1A_ not modelled 8.9 19 PDB header:hydrolase Chain: A: PDB Molecule:p22 protein; PDBTitle: crystal structure of the trypanosoma brucei p22 protein 85 c2x24B_ not modelled 8.6 13 PDB header:ligase Chain: B: PDB Molecule:acetyl-coa carboxylase; PDBTitle: bovine acc2 ct domain in complex with inhibitor 86 c3ip3D_ not modelled 8.6 14 PDB header:oxidoreductase Chain: D: PDB Molecule:oxidoreductase, putative; PDBTitle: structure of putative oxidoreductase (tm_0425) from2 thermotoga maritima 87 c3b20R_ not modelled 8.5 17 PDB header:oxidoreductase Chain: R: PDB Molecule:glyceraldehyde 3-phosphate dehydrogenase (nadp+); PDBTitle: crystal structure analysis of dehydrogenase complexed with nad 88 d1mv8a2 not modelled 8.3 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 89 c2dxbR_ not modelled 8.1 25 PDB header:hydrolase Chain: R: PDB Molecule:thiocyanate hydrolase subunit gamma; PDBTitle: recombinant thiocyanate hydrolase comprising partially-modified cobalt2 centers 90 d1xdpa3 not modelled 8.0 50 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 91 c2z8jA_ not modelled 7.9 26 PDB header:transferase Chain: A: PDB Molecule:gamma-glutamyltranspeptidase; PDBTitle: crystal structure of escherichia coli gamma-2 glutamyltranspeptidase in complex with azaserine prepared3 in the dark 92 c2ew2B_ not modelled 7.9 12 PDB header:oxidoreductase Chain: B: PDB Molecule:2-dehydropantoate 2-reductase, putative; PDBTitle: crystal structure of the putative 2-dehydropantoate 2-reductase from2 enterococcus faecalis 93 c3d1lB_ not modelled 7.8 15 PDB header:oxidoreductase Chain: B: PDB Molecule:putative nadp oxidoreductase bf3122; PDBTitle: crystal structure of putative nadp oxidoreductase bf3122 from2 bacteroides fragilis 94 d2ouxa1 not modelled 7.8 17 Fold:alpha-alpha superhelix Superfamily:MgtE N-terminal domain-like Family:MgtE N-terminal domain-like 95 d1ryda1 not modelled 7.8 6 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 96 c2jz1A_ not modelled 7.8 23 PDB header:transcription Chain: A: PDB Molecule:protein doublesex; PDBTitle: dsx_long 97 d1g7sa3 not modelled 7.7 7 Fold:Initiation factor IF2/eIF5b, domain 3 Superfamily:Initiation factor IF2/eIF5b, domain 3 Family:Initiation factor IF2/eIF5b, domain 3 98 c3pu6A_ not modelled 7.7 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of an uncharacterized protein from wolinella2 succinogenes 99 d1ebda2 not modelled 7.7 13 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0