Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	R	K	A	F	V	M	Q	V	N	P	D	A	H	E	E	Y	Q	R	R	H	N	P	I	W	P	E	L	E	A	V	L	K	S	H	G	A	H	N	Y	A	I	Y	L	D	K	A	R	N	L	L	F	A	M	V	E	I	E	S
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.
Sequence		E	E	R	W	N	A	V	A	S	T	D	V	C	Q	R	W	W	K	Y	M	T	D	V	M	P	A	N	P	D	N	S	P	V	S	S	E	L	Q	E	V	F	Y	L	P
Secondary structure
SS confidence
Disorder										?																	?			?	?	?	?	?	?	?		?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1x8d chain A domain 1 Region: 1 - 104 Aligned: 104 Modelled: 104 Confidence: 100.0% Identity: 100% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: YiiL-like Phyre2 PDB 2qlw chain A Region: 1 - 104 Aligned: 104 Modelled: 104 Confidence: 100.0% Identity: 38% PDB header:isomerase Chain: A: PDB Molecule:rhau; PDBTitle: crystal structure of rhamnose mutarotase rhau of rhizobium2 leguminosarum Phyre2 PDB 2qlx chain A Region: 1 - 104 Aligned: 104 Modelled: 104 Confidence: 100.0% Identity: 38% PDB header:isomerase Chain: A: PDB Molecule:l-rhamnose mutarotase; PDBTitle: crystal structure of rhamnose mutarotase rhau of rhizobium2 leguminosarum in complex with l-rhamnose Phyre2 PDB 3bm7 chain A Region: 1 - 89 Aligned: 86 Modelled: 88 Confidence: 97.2% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:protein of unknown function with ferredoxin-like fold; PDBTitle: crystal structure of a putative antibiotic biosynthesis monooxygenase2 (cc_2132) from caulobacter crescentus cb15 at 1.35 a resolution Phyre2 PDB 2fb0 chain A Region: 3 - 86 Aligned: 81 Modelled: 83 Confidence: 97.1% Identity: 17% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of conserved protein of unknown function from2 bacteroides thetaiotaomicron vpi-5482 at 2.10 a resolution, possible3 oxidoreductase Phyre2 PDB 3e8o chain B Region: 4 - 89 Aligned: 83 Modelled: 86 Confidence: 96.9% Identity: 8% PDB header:oxidoreductase Chain: B: PDB Molecule:uncharacterized protein with erredoxin-like fold; PDBTitle: crystal structure of a putative antibiotic biosynthesis monooxygenase2 (dr_2100) from deinococcus radiodurans at 1.40 a resolution Phyre2 PDB 2omo chain A domain 1 Region: 7 - 89 Aligned: 80 Modelled: 83 Confidence: 96.8% Identity: 15% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: PA3566-like Phyre2 PDB 3f44 chain A Region: 7 - 86 Aligned: 77 Modelled: 77 Confidence: 96.7% Identity: 9% PDB header:oxidoreductase Chain: A: PDB Molecule:putative monooxygenase; PDBTitle: crystal structure of putative monooxygenase (yp_193413.1) from2 lactobacillus acidophilus ncfm at 1.55 a resolution Phyre2 PDB 2omo chain C Region: 7 - 88 Aligned: 79 Modelled: 82 Confidence: 96.6% Identity: 15% PDB header:oxidoreductase Chain: C: PDB Molecule:duf176; PDBTitle: putative antibiotic biosynthesis monooxygenase from nitrosomonas2 europaea Phyre2 PDB 1y0h chain A Region: 4 - 89 Aligned: 83 Modelled: 86 Confidence: 96.6% Identity: 10% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: PA3566-like Phyre2 PDB 2gff chain B Region: 3 - 89 Aligned: 83 Modelled: 87 Confidence: 96.5% Identity: 10% PDB header:sugar binding protein Chain: B: PDB Molecule:lsrg protein; PDBTitle: crystal structure of yersinia pestis lsrg Phyre2 PDB 2bbe chain A Region: 1 - 89 Aligned: 86 Modelled: 89 Confidence: 96.5% Identity: 9% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein so0527; PDBTitle: crystal structure of protein so0527 from shewanella oneidensis Phyre2 PDB 2pd1 chain A domain 1 Region: 3 - 89 Aligned: 82 Modelled: 87 Confidence: 96.3% Identity: 10% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: PA3566-like Phyre2 PDB 1x7v chain A Region: 1 - 86 Aligned: 83 Modelled: 86 Confidence: 96.2% Identity: 13% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: PA3566-like Phyre2 PDB 3gz7 chain B Region: 3 - 88 Aligned: 83 Modelled: 86 Confidence: 96.0% Identity: 13% PDB header:biosynthetic protein Chain: B: PDB Molecule:putative antibiotic biosynthesis monooxygenase; PDBTitle: crystal structure of putative antibiotic biosynthesis2 monooxygenase (np_888398.1) from bordetella bronchiseptica3 at 2.15 a resolution Phyre2 PDB 3mcs chain B Region: 7 - 86 Aligned: 77 Modelled: 76 Confidence: 96.0% Identity: 14% PDB header:oxidoreductase Chain: B: PDB Molecule:putative monooxygenase; PDBTitle: crystal structure of putative monooxygenase (fn1347) from2 fusobacterium nucleatum subsp. nucleatum atcc 25586 at 2.55 a3 resolution Phyre2 PDB 3fgv chain B Region: 2 - 89 Aligned: 85 Modelled: 88 Confidence: 95.5% Identity: 9% PDB header:oxidoreductase Chain: B: PDB Molecule:uncharacterized protein with ferredoxin-like fold; PDBTitle: crystal structure of a putative antibiotic biosynthesis monooxygenase2 (spo2313) from silicibacter pomeroyi dss-3 at 1.30 a resolution Phyre2 PDB 3kkf chain A Region: 7 - 86 Aligned: 77 Modelled: 73 Confidence: 95.0% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:putative antibiotic biosynthesis monooxygenase; PDBTitle: crystal structure of putative antibiotic biosynthesis2 monooxygenase (np_810307.1) from bacteriodes3 thetaiotaomicron vpi-5482 at 1.30 a resolution Phyre2 PDB 1tuv chain A Region: 1 - 86 Aligned: 85 Modelled: 86 Confidence: 93.8% Identity: 20% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: PA3566-like Phyre2 PDB 1iuj chain A Region: 1 - 100 Aligned: 97 Modelled: 100 Confidence: 90.0% Identity: 13% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: PG130-like Phyre2 1 d1x8da1 2 c2qlwA_ 3 c2qlxA_ 4 c3bm7A_ 5 c2fb0A_ 6 c3e8oB_ 7 d2omoa1 8 c3f44A_ 9 c2omoC_ 10 d1y0ha_ 11 c2gffB_ 12 c2bbeA_ 13 d2pd1a1 14 d1x7va_ 15 c3gz7B_ 16 c3mcsB_ 17 c3fgvB_ 18 c3kkfA_ 19 d1tuva_ 20 d1iuja_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1x8da1 100.0 100 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:YiiL-like 2 c2qlwA_ 100.0 38 PDB header:isomerase Chain: A: PDB Molecule:rhau; PDBTitle: crystal structure of rhamnose mutarotase rhau of rhizobium2 leguminosarum 3 c2qlxA_ 100.0 38 PDB header:isomerase Chain: A: PDB Molecule:l-rhamnose mutarotase; PDBTitle: crystal structure of rhamnose mutarotase rhau of rhizobium2 leguminosarum in complex with l-rhamnose 4 c3bm7A_ 97.2 15 PDB header:oxidoreductase Chain: A: PDB Molecule:protein of unknown function with ferredoxin-like fold; PDBTitle: crystal structure of a putative antibiotic biosynthesis monooxygenase2 (cc_2132) from caulobacter crescentus cb15 at 1.35 a resolution 5 c2fb0A_ 97.1 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of conserved protein of unknown function from2 bacteroides thetaiotaomicron vpi-5482 at 2.10 a resolution, possible3 oxidoreductase 6 c3e8oB_ 96.9 8 PDB header:oxidoreductase Chain: B: PDB Molecule:uncharacterized protein with erredoxin-like fold; PDBTitle: crystal structure of a putative antibiotic biosynthesis monooxygenase2 (dr_2100) from deinococcus radiodurans at 1.40 a resolution 7 d2omoa1 96.8 15 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PA3566-like 8 c3f44A_ 96.7 9 PDB header:oxidoreductase Chain: A: PDB Molecule:putative monooxygenase; PDBTitle: crystal structure of putative monooxygenase (yp_193413.1) from2 lactobacillus acidophilus ncfm at 1.55 a resolution 9 c2omoC_ 96.6 15 PDB header:oxidoreductase Chain: C: PDB Molecule:duf176; PDBTitle: putative antibiotic biosynthesis monooxygenase from nitrosomonas2 europaea 10 d1y0ha_ 96.6 10 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PA3566-like 11 c2gffB_ 96.5 10 PDB header:sugar binding protein Chain: B: PDB Molecule:lsrg protein; PDBTitle: crystal structure of yersinia pestis lsrg 12 c2bbeA_ 96.5 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein so0527; PDBTitle: crystal structure of protein so0527 from shewanella oneidensis 13 d2pd1a1 96.3 10 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PA3566-like 14 d1x7va_ 96.2 13 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PA3566-like 15 c3gz7B_ 96.0 13 PDB header:biosynthetic protein Chain: B: PDB Molecule:putative antibiotic biosynthesis monooxygenase; PDBTitle: crystal structure of putative antibiotic biosynthesis2 monooxygenase (np_888398.1) from bordetella bronchiseptica3 at 2.15 a resolution 16 c3mcsB_ 96.0 14 PDB header:oxidoreductase Chain: B: PDB Molecule:putative monooxygenase; PDBTitle: crystal structure of putative monooxygenase (fn1347) from2 fusobacterium nucleatum subsp. nucleatum atcc 25586 at 2.55 a3 resolution 17 c3fgvB_ 95.5 9 PDB header:oxidoreductase Chain: B: PDB Molecule:uncharacterized protein with ferredoxin-like fold; PDBTitle: crystal structure of a putative antibiotic biosynthesis monooxygenase2 (spo2313) from silicibacter pomeroyi dss-3 at 1.30 a resolution 18 c3kkfA_ 95.0 18 PDB header:oxidoreductase Chain: A: PDB Molecule:putative antibiotic biosynthesis monooxygenase; PDBTitle: crystal structure of putative antibiotic biosynthesis2 monooxygenase (np_810307.1) from bacteriodes3 thetaiotaomicron vpi-5482 at 1.30 a resolution 19 d1tuva_ 93.8 20 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PA3566-like 20 d1iuja_ 90.0 13 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PG130-like 21 d1vqsa_ not modelled 89.1 16 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:NIPSNAP 22 d1vqya1 not modelled 87.3 11 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:NIPSNAP 23 c3kngA_ not modelled 84.3 10 PDB header:oxidoreductase Chain: A: PDB Molecule:snoab; PDBTitle: crystal structure of snoab, a cofactor-independent oxygenase2 from streptomyces nogalater, determined to 1.9 resolution 24 d1q8ba_ not modelled 70.9 18 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Hypothetical protein YjcS 25 c3hx9B_ not modelled 64.4 17 PDB header:oxidoreductase Chain: B: PDB Molecule:protein rv3592; PDBTitle: structure of heme-degrader, mhud (rv3592), from2 mycobacterium tuberculosis with two hemes bound in its3 active site 26 d2atza1 not modelled 55.8 19 Fold:Prim-pol domain Superfamily:Prim-pol domain Family:HP0184-like 27 d1tuwa_ not modelled 29.0 17 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Polyketide synthesis cyclase 28 c3louB_ not modelled 21.9 11 PDB header:hydrolase Chain: B: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of formyltetrahydrofolate deformylase (yp_105254.1)2 from burkholderia mallei atcc 23344 at 1.90 a resolution 29 c3fj2A_ not modelled 21.5 8 PDB header:unknown function Chain: A: PDB Molecule:monooxygenase-like protein; PDBTitle: crystal structure of a monooxygenase-like protein (lin2316) from2 listeria innocua at 1.85 a resolution 30 d2cz4a1 not modelled 20.5 33 Fold:Ferredoxin-like Superfamily:GlnB-like Family:Prokaryotic signal transducing protein 31 d2zdpa1 not modelled 18.9 17 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PG130-like 32 c2x7vA_ not modelled 18.3 19 PDB header:hydrolase Chain: A: PDB Molecule:probable endonuclease 4; PDBTitle: crystal structure of thermotoga maritima endonuclease iv in2 the presence of zinc 33 c3thdD_ not modelled 18.0 22 PDB header:hydrolase Chain: D: PDB Molecule:beta-galactosidase; PDBTitle: crystal structure of human beta-galactosidase in complex with 1-2 deoxygalactonojirimycin 34 d2ns1b1 not modelled 16.1 17 Fold:Ferredoxin-like Superfamily:GlnB-like Family:Prokaryotic signal transducing protein 35 c2jdjB_ not modelled 12.2 5 PDB header:biosynthetic protein Chain: B: PDB Molecule:redy-like protein; PDBTitle: crystal structure of hapk from hahella chejuensis 36 c2rodB_ not modelled 11.7 33 PDB header:apoptosis Chain: B: PDB Molecule:noxa; PDBTitle: solution structure of mcl-1 complexed with noxaa 37 c3obiC_ not modelled 10.9 15 PDB header:hydrolase Chain: C: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (np_949368)2 from rhodopseudomonas palustris cga009 at 1.95 a resolution 38 c2qqdG_ not modelled 10.8 31 PDB header:lyase Chain: G: PDB Molecule:pyruvoyl-dependent arginine decarboxylase (ec PDBTitle: n47a mutant of pyruvoyl-dependent arginine decarboxylase2 from methanococcus jannashii 39 d1vfja_ not modelled 10.3 11 Fold:Ferredoxin-like Superfamily:GlnB-like Family:Prokaryotic signal transducing protein 40 c3mhyC_ not modelled 10.2 22 PDB header:signaling protein Chain: C: PDB Molecule:pii-like protein pz; PDBTitle: a new pii protein structure 41 c3o8wA_ not modelled 10.1 11 PDB header:signaling protein Chain: A: PDB Molecule:nitrogen regulatory protein p-ii (glnb-1); PDBTitle: archaeoglobus fulgidus glnk1 42 d2hh8a1 not modelled 10.1 21 Fold:YdfO-like Superfamily:YdfO-like Family:YdfO-like 43 c3hfkB_ not modelled 9.8 22 PDB header:isomerase Chain: B: PDB Molecule:4-methylmuconolactone methylisomerase; PDBTitle: crystal structure of 4-methylmuconolactone methylisomerase2 (h52a) in complex with 4-methylmuconolactone 44 c3d3aA_ not modelled 9.7 22 PDB header:hydrolase Chain: A: PDB Molecule:beta-galactosidase; PDBTitle: crystal structure of a beta-galactosidase from bacteroides2 thetaiotaomicron 45 c2hfqA_ not modelled 9.4 33 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: nmr structure of protein ne1680 from nitrosomonas europaea:2 northeast structural genomics consortium target net5 46 d2hfqa1 not modelled 9.4 33 Fold:NE1680-like Superfamily:NE1680-like Family:NE1680-like 47 c2rd5D_ not modelled 9.2 12 PDB header:protein binding Chain: D: PDB Molecule:pii protein; PDBTitle: structural basis for the regulation of n-acetylglutamate kinase by pii2 in arabidopsis thaliana 48 c2pfuA_ not modelled 9.1 13 PDB header:transport protein Chain: A: PDB Molecule:biopolymer transport exbd protein; PDBTitle: nmr strcuture determination of the periplasmic domain of exbd from2 e.coli 49 d1tafa_ not modelled 9.0 21 Fold:Histone-fold Superfamily:Histone-fold Family:TBP-associated factors, TAFs 50 c3bzqA_ not modelled 8.9 11 PDB header:signaling protein/transcription Chain: A: PDB Molecule:nitrogen regulatory protein p-ii; PDBTitle: high resolution crystal structure of nitrogen regulatory protein2 (rv2919c) of mycobacterium tuberculosis 51 c3ncpD_ not modelled 8.4 26 PDB header:signaling protein Chain: D: PDB Molecule:nitrogen regulatory protein p-ii (glnb-2); PDBTitle: glnk2 from archaeoglobus fulgidus 52 d1qy7a_ not modelled 8.1 17 Fold:Ferredoxin-like Superfamily:GlnB-like Family:Prokaryotic signal transducing protein 53 c2lf3A_ not modelled 7.6 28 PDB header:signaling protein Chain: A: PDB Molecule:effector protein hopab3; PDBTitle: solution nmr structure of hoppmal_281_385 from pseudomonas syringae2 pv. maculicola str. es4326, midwest center for structural genomics3 target apc40104.5 and northeast structural genomics consortium target4 pst2a 54 c3ogrA_ not modelled 7.5 15 PDB header:hydrolase Chain: A: PDB Molecule:beta-galactosidase; PDBTitle: complex structure of beta-galactosidase from trichoderma reesei with2 galactose 55 c1xc6A_ not modelled 7.2 15 PDB header:hydrolase Chain: A: PDB Molecule:beta-galactosidase; PDBTitle: native structure of beta-galactosidase from penicillium sp. in complex2 with galactose 56 c2k42A_ not modelled 7.1 19 PDB header:signaling protein Chain: A: PDB Molecule:wiskott-aldrich syndrome protein; PDBTitle: solution structure of the gtpase binding domain of wasp in2 complex with espfu, an ehec effector 57 d2piia_ not modelled 7.0 11 Fold:Ferredoxin-like Superfamily:GlnB-like Family:Prokaryotic signal transducing protein 58 c1ceeB_ not modelled 7.0 18 PDB header:structural protein regulation Chain: B: PDB Molecule:wiskott-aldrich syndrome protein wasp; PDBTitle: solution structure of cdc42 in complex with the gtpase2 binding domain of wasp 59 c2dclB_ not modelled 6.6 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical upf0166 protein ph1503; PDBTitle: structure of ph1503 protein from pyrococcus horikoshii ot3 60 c3s8sA_ not modelled 6.6 21 PDB header:transcription Chain: A: PDB Molecule:histone-lysine n-methyltransferase setd1a; PDBTitle: crystal structure of the rrm domain of human setd1a 61 c2j9dG_ not modelled 6.0 11 PDB header:membrane transport Chain: G: PDB Molecule:hypothetical nitrogen regulatory pii-like PDBTitle: structure of glnk1 with bound effectors indicates2 regulatory mechanism for ammonia uptake 62 d1gx5a_ not modelled 5.7 11 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:RNA-dependent RNA-polymerase 63 c3n0vD_ not modelled 5.7 15 PDB header:hydrolase Chain: D: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pp_0327)2 from pseudomonas putida kt2440 at 2.25 a resolution 64 d1hwua_ not modelled 5.5 16 Fold:Ferredoxin-like Superfamily:GlnB-like Family:Prokaryotic signal transducing protein 65 c3mjkE_ not modelled 5.2 20 PDB header:hormone Chain: E: PDB Molecule:platelet-derived growth factor subunit a; PDBTitle: structure of a growth factor precursor 66 c3nrbD_ not modelled 5.2 15 PDB header:hydrolase Chain: D: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (puru,2 pp_1943) from pseudomonas putida kt2440 at 2.05 a resolution 67 d1p42a1 not modelled 5.1 20 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC 68 d1qw1a1 not modelled 5.1 8 Fold:SH3-like barrel Superfamily:C-terminal domain of transcriptional repressors Family:FeoA-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0