Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	E	Q	M	G	I	A	A	K	Q	A	S	Y	K	L	A	Q	L	S	S	R	E	K	N	R	V	L	E	K	I	A	D	E	L	E	A	Q	S	E	I	I	L	N	A	N	A	Q	D	V	A	D	A	R	A	N	G	L	S	E
Secondary structure
SS confidence
Disorder		?																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	M	L	D	R	L	A	L	T	P	A	R	L	K	G	I	A	D	D	V	R	Q	V	C	N	L	A	D	P	V	G	Q	V	I	D	G	G	V	L	D	S	G	L	R	L	E	R	R	R	V	P	L	G	V	I	G	V	I	Y	E
Secondary structure
SS confidence
Disorder																																	?		?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	R	P	N	V	T	V	D	V	A	S	L	C	L	K	T	G	N	A	V	I	L	R	G	G	K	E	T	C	R	T	N	A	A	T	V	A	V	I	Q	D	A	L	K	S	C	G	L	P	A	G	A	V	Q	A	I	D	N	P	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	A	L	V	S	E	M	L	R	M	D	K	Y	I	D	M	L	I	P	R	G	G	A	G	L	H	K	L	C	R	E	Q	S	T	I	P	V	I	T	G	G	I	G	V	C	H	I	Y	V	D	E	S	V	E	I	A	E	A	L	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	I	V	N	A	K	T	Q	R	P	S	T	C	N	T	V	E	T	L	L	V	N	K	N	I	A	D	S	F	L	P	A	L	S	K	Q	M	A	E	S	G	V	T	L	H	A	D	A	A	A	L	A	Q	L	Q	A	G	P	A	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	V	A	V	K	A	E	E	Y	D	D	E	F	L	S	L	D	L	N	V	K	I	V	S	D	L	D	D	A	I	A	H	I	R	E	H	G	T	Q	H	S	D	A	I	L	T	R	D	M	R	N	A	Q	R	F	V	N	E	V	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.
Sequence		S	S	A	V	Y	V	N	A	S	T	R	F	T	D	G	G	Q	F	G	L	G	A	E	V	A	V	S	T	Q	K	L	H	A	R	G	P	M	G	L	E	A	L	T	T	Y	K	W	I	G	I	G	D	Y	T	I	R	A
Secondary structure
SS confidence
Disorder																							?			?		?	?	?	?	?		?																				?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1o20 chain A Region: 2 - 416 Aligned: 411 Modelled: 415 Confidence: 100.0% Identity: 46% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 2h5g chain A Region: 2 - 415 Aligned: 389 Modelled: 400 Confidence: 100.0% Identity: 36% PDB header:oxidoreductase Chain: A: PDB Molecule:delta 1-pyrroline-5-carboxylate synthetase; PDBTitle: crystal structure of human pyrroline-5-carboxylate synthetase Phyre2 PDB 3haz chain A Region: 2 - 410 Aligned: 388 Modelled: 393 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:proline dehydrogenase; PDBTitle: crystal structure of bifunctional proline utilization a2 (puta) protein Phyre2 PDB 1uzb chain A Region: 2 - 411 Aligned: 391 Modelled: 398 Confidence: 100.0% Identity: 17% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 1a4s chain A Region: 2 - 417 Aligned: 392 Modelled: 401 Confidence: 100.0% Identity: 17% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 1vlu chain A Region: 2 - 416 Aligned: 383 Modelled: 393 Confidence: 100.0% Identity: 36% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 3qan chain B Region: 2 - 410 Aligned: 390 Modelled: 397 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: B: PDB Molecule:1-pyrroline-5-carboxylate dehydrogenase 1; PDBTitle: crystal structure of 1-pyrroline-5-carboxylate dehydrogenase from2 bacillus halodurans Phyre2 PDB 2jg7 chain G Region: 2 - 413 Aligned: 394 Modelled: 400 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: G: PDB Molecule:antiquitin; PDBTitle: crystal structure of seabream antiquitin and elucidation of2 its substrate specificity Phyre2 PDB 3ed6 chain B Region: 2 - 413 Aligned: 390 Modelled: 398 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: B: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: 1.7 angstrom resolution crystal structure of betaine aldehyde2 dehydrogenase (betb) from staphylococcus aureus Phyre2 PDB 1ad3 chain A Region: 2 - 412 Aligned: 391 Modelled: 404 Confidence: 100.0% Identity: 16% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 1bxs chain A Region: 2 - 414 Aligned: 390 Modelled: 399 Confidence: 100.0% Identity: 20% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 1o9j chain A Region: 2 - 417 Aligned: 393 Modelled: 402 Confidence: 100.0% Identity: 18% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 2ve5 chain H Region: 2 - 416 Aligned: 393 Modelled: 398 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: H: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystallographic structure of betaine aldehyde2 dehydrogenase from pseudomonas aeruginosa Phyre2 PDB 2d4e chain B Region: 2 - 414 Aligned: 390 Modelled: 399 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: B: PDB Molecule:5-carboxymethyl-2-hydroxymuconate semialdehyde PDBTitle: crystal structure of the hpcc from thermus thermophilus hb8 Phyre2 PDB 1ag8 chain A Region: 2 - 414 Aligned: 390 Modelled: 398 Confidence: 100.0% Identity: 18% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 2o2q chain A Region: 2 - 410 Aligned: 388 Modelled: 397 Confidence: 100.0% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:formyltetrahydrofolate dehydrogenase; PDBTitle: crystal structure of the c-terminal domain of rat2 10'formyltetrahydrofolate dehydrogenase in complex with nadp Phyre2 PDB 1euh chain A Region: 2 - 410 Aligned: 389 Modelled: 397 Confidence: 100.0% Identity: 17% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 3rh9 chain A Region: 2 - 411 Aligned: 388 Modelled: 396 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase (nad(p)(+)); PDBTitle: the crystal structure of oxidoreductase from marinobacter aquaeolei Phyre2 PDB 3prl chain D Region: 2 - 414 Aligned: 393 Modelled: 401 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: D: PDB Molecule:nadp-dependent glyceraldehyde-3-phosphate dehydrogenase; PDBTitle: crystal structure of nadp-dependent glyceraldehyde-3-phosphate2 dehydrogenase from bacillus halodurans c-125 Phyre2 PDB 1wnd chain A Region: 2 - 411 Aligned: 388 Modelled: 397 Confidence: 100.0% Identity: 16% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 1vlu chain B Region: 2 - 416 Aligned: 383 Modelled: 378 Confidence: 100.0% Identity: 38% PDB header:oxidoreductase Chain: B: PDB Molecule:gamma-glutamyl phosphate reductase; PDBTitle: crystal structure of gamma-glutamyl phosphate reductase (yor323c) from2 saccharomyces cerevisiae at 2.40 a resolution Phyre2 1 d1o20a_ 2 c2h5gA_ 3 c3hazA_ 4 d1uzba_ 5 d1a4sa_ 6 d1vlua_ 7 c3qanB_ 8 c2jg7G_ 9 c3ed6B_ 10 d1ad3a_ 11 d1bxsa_ 12 d1o9ja_ 13 c2ve5H_ 14 c2d4eB_ 15 d1ag8a_ 16 c2o2qA_ 17 d1euha_ 18 c3rh9A_ 19 c3prlD_ 20 d1wnda_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 c1vluB_ 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1o20a_ 100.0 46 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 2 c2h5gA_ 100.0 36 PDB header:oxidoreductase Chain: A: PDB Molecule:delta 1-pyrroline-5-carboxylate synthetase; PDBTitle: crystal structure of human pyrroline-5-carboxylate synthetase 3 c3hazA_ 100.0 19 PDB header:oxidoreductase Chain: A: PDB Molecule:proline dehydrogenase; PDBTitle: crystal structure of bifunctional proline utilization a2 (puta) protein 4 d1uzba_ 100.0 17 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 5 d1a4sa_ 100.0 17 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 6 d1vlua_ 100.0 36 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 7 c3qanB_ 100.0 17 PDB header:oxidoreductase Chain: B: PDB Molecule:1-pyrroline-5-carboxylate dehydrogenase 1; PDBTitle: crystal structure of 1-pyrroline-5-carboxylate dehydrogenase from2 bacillus halodurans 8 c2jg7G_ 100.0 19 PDB header:oxidoreductase Chain: G: PDB Molecule:antiquitin; PDBTitle: crystal structure of seabream antiquitin and elucidation of2 its substrate specificity 9 c3ed6B_ 100.0 18 PDB header:oxidoreductase Chain: B: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: 1.7 angstrom resolution crystal structure of betaine aldehyde2 dehydrogenase (betb) from staphylococcus aureus 10 d1ad3a_ 100.0 16 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 11 d1bxsa_ 100.0 20 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 12 d1o9ja_ 100.0 18 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 13 c2ve5H_ 100.0 17 PDB header:oxidoreductase Chain: H: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystallographic structure of betaine aldehyde2 dehydrogenase from pseudomonas aeruginosa 14 c2d4eB_ 100.0 17 PDB header:oxidoreductase Chain: B: PDB Molecule:5-carboxymethyl-2-hydroxymuconate semialdehyde PDBTitle: crystal structure of the hpcc from thermus thermophilus hb8 15 d1ag8a_ 100.0 18 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 16 c2o2qA_ 100.0 16 PDB header:oxidoreductase Chain: A: PDB Molecule:formyltetrahydrofolate dehydrogenase; PDBTitle: crystal structure of the c-terminal domain of rat2 10'formyltetrahydrofolate dehydrogenase in complex with nadp 17 d1euha_ 100.0 17 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 18 c3rh9A_ 100.0 17 PDB header:oxidoreductase Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase (nad(p)(+)); PDBTitle: the crystal structure of oxidoreductase from marinobacter aquaeolei 19 c3prlD_ 100.0 19 PDB header:oxidoreductase Chain: D: PDB Molecule:nadp-dependent glyceraldehyde-3-phosphate dehydrogenase; PDBTitle: crystal structure of nadp-dependent glyceraldehyde-3-phosphate2 dehydrogenase from bacillus halodurans c-125 20 d1wnda_ 100.0 16 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 21 c2w8qA_ not modelled 100.0 17 PDB header:oxidoreductase Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase, PDBTitle: the crystal structure of human ssadh in complex with ssa. 22 d1o04a_ not modelled 100.0 18 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 23 c3iwkB_ not modelled 100.0 18 PDB header:oxidoreductase Chain: B: PDB Molecule:aminoaldehyde dehydrogenase; PDBTitle: crystal structure of aminoaldehyde dehydrogenase 1 from2 pisum sativum (psamadh1) 24 d1ky8a_ not modelled 100.0 20 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 25 c3ifgH_ not modelled 100.0 16 PDB header:oxidoreductase Chain: H: PDB Molecule:succinate-semialdehyde dehydrogenase (nadp+); PDBTitle: crystal structure of succinate-semialdehyde dehydrogenase from2 burkholderia pseudomallei, part 1 of 2 26 c3ek1C_ not modelled 100.0 19 PDB header:oxidoreductase Chain: C: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from brucella2 melitensis biovar abortus 2308 27 c1t90B_ not modelled 100.0 17 PDB header:oxidoreductase Chain: B: PDB Molecule:probable methylmalonate-semialdehyde PDBTitle: crystal structure of methylmalonate semialdehyde2 dehydrogenase from bacillus subtilis 28 c3rosA_ not modelled 100.0 16 PDB header:oxidoreductase Chain: A: PDB Molecule:nad-dependent aldehyde dehydrogenase; PDBTitle: crystal structure of nad-dependent aldehyde dehydrogenase from2 lactobacillus acidophilus 29 c3r31A_ not modelled 100.0 18 PDB header:oxidoreductase Chain: A: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystal structure of betaine aldehyde dehydrogenase from agrobacterium2 tumefaciens 30 c3k2wD_ not modelled 100.0 19 PDB header:oxidoreductase Chain: D: PDB Molecule:betaine-aldehyde dehydrogenase; PDBTitle: crystal structure of betaine-aldehyde dehydrogenase from2 pseudoalteromonas atlantica t6c 31 c3jz4C_ not modelled 100.0 19 PDB header:oxidoreductase Chain: C: PDB Molecule:succinate-semialdehyde dehydrogenase [nadp+]; PDBTitle: crystal structure of e. coli nadp dependent enzyme 32 c3b4wA_ not modelled 100.0 19 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of mycobacterium tuberculosis aldehyde dehydrogenase2 complexed with nad+ 33 c3i44A_ not modelled 100.0 16 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from bartonella2 henselae at 2.0a resolution 34 c1vluB_ 100.0 38 PDB header:oxidoreductase Chain: B: PDB Molecule:gamma-glutamyl phosphate reductase; PDBTitle: crystal structure of gamma-glutamyl phosphate reductase (yor323c) from2 saccharomyces cerevisiae at 2.40 a resolution 35 c3k9dD_ not modelled 100.0 19 PDB header:oxidoreductase Chain: D: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of probable aldehyde dehydrogenase from listeria2 monocytogenes egd-e 36 c2hg2A_ not modelled 100.0 19 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase a; PDBTitle: structure of lactaldehyde dehydrogenase 37 c3pqaA_ not modelled 100.0 16 PDB header:oxidoreductase Chain: A: PDB Molecule:lactaldehyde dehydrogenase; PDBTitle: crystal structure of glyceraldehyde-3-phosphate dehydrogenase gapn2 from methanocaldococcus jannaschii dsm 2661 38 c3v4cB_ not modelled 100.0 18 PDB header:oxidoreductase Chain: B: PDB Molecule:aldehyde dehydrogenase (nadp+); PDBTitle: crystal structure of a semialdehyde dehydrogenase from sinorhizobium2 meliloti 1021 39 c3efvC_ not modelled 100.0 17 PDB header:oxidoreductase Chain: C: PDB Molecule:putative succinate-semialdehyde dehydrogenase; PDBTitle: crystal structure of a putative succinate-semialdehyde dehydrogenase2 from salmonella typhimurium lt2 with bound nad 40 d1ez0a_ not modelled 100.0 18 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 41 c3ju8B_ not modelled 100.0 20 PDB header:oxidoreductase Chain: B: PDB Molecule:succinylglutamic semialdehyde dehydrogenase; PDBTitle: crystal structure of succinylglutamic semialdehyde dehydrogenase from2 pseudomonas aeruginosa. 42 d1bi9a_ not modelled 100.0 18 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 43 c2vroB_ not modelled 100.0 20 PDB header:oxidoreductase Chain: B: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from2 burkholderia xenovorans lb400 44 c3lnsD_ not modelled 100.0 18 PDB header:oxidoreductase Chain: D: PDB Molecule:benzaldehyde dehydrogenase; PDBTitle: benzaldehyde dehydrogenase, a class 3 aldehyde dehydrogenase, with2 bound nadp+ and benzoate adduct 45 c3r64A_ not modelled 100.0 17 PDB header:oxidoreductase Chain: A: PDB Molecule:nad dependent benzaldehyde dehydrogenase; PDBTitle: crystal structure of a nad-dependent benzaldehyde dehydrogenase from2 corynebacterium glutamicum 46 c3my7A_ not modelled 100.0 19 PDB header:oxidoreductase Chain: A: PDB Molecule:alcohol dehydrogenase/acetaldehyde dehydrogenase; PDBTitle: the crystal structure of the acdh domain of an alcohol dehydrogenase2 from vibrio parahaemolyticus to 2.25a 47 d1k75a_ not modelled 98.5 16 Fold:ALDH-like Superfamily:ALDH-like Family:L-histidinol dehydrogenase HisD 48 c3jtpB_ not modelled 50.5 14 PDB header:protein binding Chain: B: PDB Molecule:adapter protein meca 1; PDBTitle: crystal structure of the c-terminal domain of meca 49 c2yukA_ not modelled 47.6 26 PDB header:transferase Chain: A: PDB Molecule:myeloid/lymphoid or mixed-lineage leukemia PDBTitle: solution structure of the hmg box of human myeloid/lymphoid2 or mixed-lineage leukemia protein 3 homolog 50 d1k99a_ not modelled 36.6 17 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 51 d1s7ia_ not modelled 35.7 11 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:DGPF domain (Pfam 04946) 52 d1g62a_ not modelled 32.9 17 Fold:Pentein, beta/alpha-propeller Superfamily:Pentein Family:Ribosome anti-association factor eIF6 (aIF6) 53 c2crjA_ not modelled 31.2 18 PDB header:gene regulation Chain: A: PDB Molecule:swi/snf-related matrix-associated actin- PDBTitle: solution structure of the hmg domain of mouse hmg domain2 protein hmgx2 54 c3fghA_ not modelled 30.2 13 PDB header:transcription Chain: A: PDB Molecule:transcription factor a, mitochondrial; PDBTitle: human mitochondrial transcription factor a box b 55 c2ec4A_ not modelled 29.1 8 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:fas-associated factor 1; PDBTitle: solution structure of the uas domain from human fas-2 associated factor 1 56 c2qguA_ not modelled 27.7 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:probable signal peptide protein; PDBTitle: three-dimensional structure of the phospholipid-binding protein from2 ralstonia solanacearum q8xv73_ralsq in complex with a phospholipid at3 the resolution 1.53 a. northeast structural genomics consortium4 target rsr89 57 c3c8eB_ not modelled 26.3 21 PDB header:transferase Chain: B: PDB Molecule:yghu, glutathione s-transferase homologue; PDBTitle: crystal structure analysis of yghu from e. coli 58 c2eqzA_ not modelled 26.3 15 PDB header:transcription Chain: A: PDB Molecule:high mobility group protein b3; PDBTitle: solution structure of the first hmg-box domain from high2 mobility group protein b3 59 d1acoa2 not modelled 25.8 7 Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain 60 d1j3xa_ not modelled 25.6 13 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 61 c1j3xA_ not modelled 25.6 13 PDB header:dna binding protein Chain: A: PDB Molecule:high mobility group protein 2; PDBTitle: solution structure of the n-terminal domain of the hmgb2 62 d1wo8a1 not modelled 24.4 10 Fold:Methylglyoxal synthase-like Superfamily:Methylglyoxal synthase-like Family:Methylglyoxal synthase, MgsA 63 c3e5bB_ not modelled 24.3 16 PDB header:lyase Chain: B: PDB Molecule:isocitrate lyase; PDBTitle: 2.4 a crystal structure of isocitrate lyase from brucella2 melitensis 64 c2cs1A_ not modelled 23.8 26 PDB header:dna binding protein Chain: A: PDB Molecule:pms1 protein homolog 1; PDBTitle: solution structure of the hmg domain of human dna mismatch2 repair protein 65 d1y5ea1 not modelled 23.6 14 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 66 d1hsma_ not modelled 21.1 19 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 67 d2ftsa3 not modelled 21.0 14 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MoeA central domain-like 68 c5acnA_ not modelled 20.8 7 PDB header:lyase(carbon-oxygen) Chain: A: PDB Molecule:aconitase; PDBTitle: structure of activated aconitase. formation of the (4fe-4s)2 cluster in the crystal 69 d1j46a_ not modelled 20.5 20 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 70 c2co9A_ not modelled 20.4 15 PDB header:transcription Chain: A: PDB Molecule:thymus high mobility group box protein tox; PDBTitle: solution structure of the hmg_box domain of thymus high2 mobility group box protein tox from mouse 71 d1lwma_ not modelled 20.4 16 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 72 d1vdha_ not modelled 20.3 7 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Chlorite dismutase-like 73 c3g5oC_ not modelled 20.2 24 PDB header:toxin/antitoxin Chain: C: PDB Molecule:uncharacterized protein rv2866; PDBTitle: the crystal structure of the toxin-antitoxin complex relbe2 (rv2865-2 2866) from mycobacterium tuberculosis 74 d1eucb2 not modelled 20.0 4 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Succinyl-CoA synthetase, beta-chain, N-terminal domain 75 d1v64a_ not modelled 19.4 18 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 76 d1v63a_ not modelled 19.2 5 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 77 d1j3da_ not modelled 19.0 21 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 78 d1u2ca2 not modelled 18.9 14 Fold:Dystroglycan, domain 2 Superfamily:Dystroglycan, domain 2 Family:Dystroglycan, domain 2 79 c2yvqA_ not modelled 18.7 23 PDB header:ligase Chain: A: PDB Molecule:carbamoyl-phosphate synthase; PDBTitle: crystal structure of mgs domain of carbamoyl-phosphate2 synthetase from homo sapiens 80 d1hmfa_ not modelled 18.5 19 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 81 c1hmfA_ not modelled 18.5 19 PDB header:dna-binding Chain: A: PDB Molecule:high mobility group protein fragment-b; PDBTitle: structure of the hmg box motif in the b-domain of hmg1 82 d2lefa_ not modelled 18.1 14 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 83 d1t0tv_ not modelled 17.9 7 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Chlorite dismutase-like 84 d2b3ya2 not modelled 17.5 14 Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain 85 d1ckta_ not modelled 16.5 14 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 86 c3labA_ not modelled 16.0 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate) PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica 87 c2b3yB_ not modelled 15.4 14 PDB header:lyase Chain: B: PDB Molecule:iron-responsive element binding protein 1; PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1) 88 d1gt0d_ not modelled 15.2 14 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 89 c1wx2A_ not modelled 15.1 16 PDB header:oxidoreductase/metal transport Chain: A: PDB Molecule:tyrosinase; PDBTitle: crystal structure of the oxy-form of the copper-bound streptomyces2 castaneoglobisporus tyrosinase complexed with a caddie protein3 prepared by the addition of hydrogenperoxide 90 d1wmia1 not modelled 14.9 25 Fold:RelE-like Superfamily:RelE-like Family:RelE-like 91 c2vxhF_ not modelled 14.5 12 PDB header:oxidoreductase Chain: F: PDB Molecule:chlorite dismutase; PDBTitle: the crystal structure of chlorite dismutase: a detox enzyme2 producing molecular oxygen 92 c1v8dC_ not modelled 14.2 21 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:hypothetical protein (tt1679); PDBTitle: crystal structure of the conserved hypothetical protein2 tt1679 from thermus thermophilus 93 d2dlxa1 not modelled 14.0 8 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:UAS domain 94 c1aabA_ not modelled 13.5 15 PDB header:dna-binding Chain: A: PDB Molecule:high mobility group protein; PDBTitle: nmr structure of rat hmg1 hmga fragment 95 d1aaba_ not modelled 13.5 15 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 96 c1usdA_ not modelled 13.5 28 PDB header:signaling protein Chain: A: PDB Molecule:vasodilator-stimulated phosphoprotein; PDBTitle: human vasp tetramerisation domain l352m 97 d2nu7b2 not modelled 13.2 9 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Succinyl-CoA synthetase, beta-chain, N-terminal domain 98 c2lhjA_ not modelled 12.8 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:high mobility group protein homolog nhp1; PDBTitle: nmr structure of the high mobility group protein-like protein nhp12 from babesia bovis t2bo (baboa.00841.a) 99 c3bpqD_ not modelled 12.7 14 PDB header:toxin Chain: D: PDB Molecule:toxin rele3; PDBTitle: crystal structure of relb-rele antitoxin-toxin complex from2 methanococcus jannaschii

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0