Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	D	Y	L	L	L	F	V	G	T	V	L	V	N	N	F	V	L	V	K	F	L	G	L	C	P	F	M	G	V	S	K	K	L	E	T	A	M	G	M	G	L	A	T	T	F	V	M	T	L	A	S	I	C	A	W	L	I	D
Secondary structure
SS confidence
Disorder		?	?	?																												?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	W	I	L	I	P	L	N	L	I	Y	L	R	T	L	A	F	I	L	V	I	A	V	V	V	Q	F	T	E	M	V	V	R	K	T	S	P	V	L	Y	R	L	L	G	I	F	L	P	L	I	T	T	N	C	A	V	L	G	V	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	L	N	I	N	L	G	H	N	F	L	Q	S	A	L	Y	G	F	S	A	A	V	G	F	S	L	V	M	V	L	F	A	A	I	R	E	R	L	A	V	A	D	V	P	A	P	F	R	G	N	A	I	A	L	I	T	A	G	L	M
Secondary structure
SS confidence
Disorder							?	?																																						?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.
Sequence		S	L	A	F	M	G	F	S	G	L	V	K	L
Secondary structure
SS confidence
Disorder									?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1ha7 chain B Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 42.7% Identity: 18% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 1cpc chain B Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 33.8% Identity: 18% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 1b8d chain A Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 31.1% Identity: 27% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 1f99 chain B Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 30.2% Identity: 18% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 1jbo chain B Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 26.6% Identity: 20% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 1lia chain A Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 24.4% Identity: 23% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 1xg0 chain C Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 22.9% Identity: 23% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 2ql2 chain A Region: 155 - 171 Aligned: 17 Modelled: 17 Confidence: 22.5% Identity: 41% PDB header:transcription/dna Chain: A: PDB Molecule:transcription factor e2-alpha; PDBTitle: crystal structure of the basic-helix-loop-helix domains of2 the heterodimer e47/neurod1 bound to dna Phyre2 PDB 2c7j chain B Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 21.5% Identity: 14% PDB header:electron transport Chain: B: PDB Molecule:phycoerythrocyanin beta chain; PDBTitle: phycoerythrocyanin from mastigocladus laminosus, 295 k,2 3.0 a Phyre2 PDB 1lia chain B Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 19.9% Identity: 30% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 3m7b chain A Region: 141 - 192 Aligned: 50 Modelled: 52 Confidence: 19.8% Identity: 12% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tellurite resistance protein teha homolog; PDBTitle: crystal structure of plant slac1 homolog teha Phyre2 PDB 2vml chain D Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 19.5% Identity: 27% PDB header:photosynthesis Chain: D: PDB Molecule:phycocyanin beta chain; PDBTitle: the monoclinic structure of phycocyanin from gloeobacter2 violaceus Phyre2 PDB 1b8d chain B Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 18.9% Identity: 23% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 1phn chain B Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 18.2% Identity: 20% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 3din chain D Region: 55 - 105 Aligned: 47 Modelled: 51 Confidence: 17.1% Identity: 17% PDB header:membrane protein, protein transport Chain: D: PDB Molecule:preprotein translocase subunit sece; PDBTitle: crystal structure of the protein-translocation complex formed by the2 secy channel and the seca atpase Phyre2 PDB 1eyx chain B Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 16.6% Identity: 30% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 1cpc chain A Region: 70 - 116 Aligned: 44 Modelled: 47 Confidence: 15.1% Identity: 18% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 1l4t chain A Region: 166 - 177 Aligned: 12 Modelled: 12 Confidence: 14.0% Identity: 25% PDB header:hormone/growth factor receptor Chain: A: PDB Molecule:gastrin/cholecystokinin type b receptor; PDBTitle: solution nmr structure of the cck2e3 Phyre2 PDB 1hzn chain A Region: 166 - 175 Aligned: 10 Modelled: 10 Confidence: 13.5% Identity: 30% PDB header:hormone/growth factor Chain: A: PDB Molecule:cholecystokinin type a receptor; PDBTitle: nmr solution structure of the third extracellular loop of2 the cholecystokinin a receptor Phyre2 PDB 2wwb chain A Region: 17 - 184 Aligned: 168 Modelled: 168 Confidence: 13.1% Identity: 12% PDB header:ribosome Chain: A: PDB Molecule:protein transport protein sec61 subunit alpha isoform 1; PDBTitle: cryo-em structure of the mammalian sec61 complex bound to the2 actively translating wheat germ 80s ribosome Phyre2 1 d1ha7b_ 2 d1cpcb_ 3 d1b8da_ 4 d1f99b_ 5 d1jbob_ 6 d1liaa_ 7 d1xg0c_ 8 c2ql2A_ 9 c2c7jB_ 10 d1liab_ 11 c3m7bA_ 12 c2vmlD_ 13 d1b8db_ 14 d1phnb_ 15 c3dinD_ 16 d1eyxb_ 17 d1cpca_ 18 c1l4tA_ 19 c1hznA_ 20 c2wwbA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1ha7b_ 42.7 18 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 2 d1cpcb_ 33.8 18 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 3 d1b8da_ 31.1 27 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 4 d1f99b_ 30.2 18 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 5 d1jbob_ 26.6 20 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 6 d1liaa_ 24.4 23 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 7 d1xg0c_ 22.9 23 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 8 c2ql2A_ 22.5 41 PDB header:transcription/dna Chain: A: PDB Molecule:transcription factor e2-alpha; PDBTitle: crystal structure of the basic-helix-loop-helix domains of2 the heterodimer e47/neurod1 bound to dna 9 c2c7jB_ 21.5 14 PDB header:electron transport Chain: B: PDB Molecule:phycoerythrocyanin beta chain; PDBTitle: phycoerythrocyanin from mastigocladus laminosus, 295 k,2 3.0 a 10 d1liab_ 19.9 30 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 11 c3m7bA_ 19.8 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tellurite resistance protein teha homolog; PDBTitle: crystal structure of plant slac1 homolog teha 12 c2vmlD_ 19.5 27 PDB header:photosynthesis Chain: D: PDB Molecule:phycocyanin beta chain; PDBTitle: the monoclinic structure of phycocyanin from gloeobacter2 violaceus 13 d1b8db_ 18.9 23 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 14 d1phnb_ 18.2 20 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 15 c3dinD_ 17.1 17 PDB header:membrane protein, protein transport Chain: D: PDB Molecule:preprotein translocase subunit sece; PDBTitle: crystal structure of the protein-translocation complex formed by the2 secy channel and the seca atpase 16 d1eyxb_ 16.6 30 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 17 d1cpca_ 15.1 18 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 18 c1l4tA_ 14.0 25 PDB header:hormone/growth factor receptor Chain: A: PDB Molecule:gastrin/cholecystokinin type b receptor; PDBTitle: solution nmr structure of the cck2e3 19 c1hznA_ 13.5 30 PDB header:hormone/growth factor Chain: A: PDB Molecule:cholecystokinin type a receptor; PDBTitle: nmr solution structure of the third extracellular loop of2 the cholecystokinin a receptor 20 c2wwbA_ 13.1 12 PDB header:ribosome Chain: A: PDB Molecule:protein transport protein sec61 subunit alpha isoform 1; PDBTitle: cryo-em structure of the mammalian sec61 complex bound to the2 actively translating wheat germ 80s ribosome 21 d1kn1a_ not modelled 12.5 25 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 22 d1eyxa_ not modelled 12.5 23 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 23 c2kbcB_ not modelled 11.3 45 PDB header:hormone Chain: B: PDB Molecule:insl5_b-chain; PDBTitle: solution structure of human insulin-like peptide 5 (insl5) 24 d1u5ta1 not modelled 10.6 26 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Vacuolar sorting protein domain 25 d1jboa_ not modelled 9.6 18 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 26 d1ha7a_ not modelled 9.1 20 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 27 c2ntxB_ not modelled 9.0 14 PDB header:signaling protein Chain: B: PDB Molecule:emb cab41934.1; 28 d1f99a_ not modelled 9.0 18 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 29 c2j96B_ not modelled 7.7 23 PDB header:photosynthesis Chain: B: PDB Molecule:phycoerythrocyanin alpha chain; PDBTitle: the e-configuration of alfa-phycoerythrocyanin 30 c3hwpA_ not modelled 6.0 38 PDB header:hydrolase Chain: A: PDB Molecule:phlg; PDBTitle: crystal structure and computational analyses provide insights into the2 catalytic mechanism of 2, 4-diacetylphloroglucinol hydrolase phlg3 from pseudomonas fluorescens 31 d1mzga_ not modelled 5.5 26 Fold:SufE/NifU Superfamily:SufE/NifU Family:SufE-like 32 d1allb_ not modelled 5.2 25 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 33 d1phna_ not modelled 5.0 11 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 34 d1b33a_ not modelled 5.0 25 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0