|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 40 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
T | S | S | L | Y | A | A | I | D | L | G | S | N | S | F | H | M | L | V | V | R | E | V | A | G | S | I | Q | T | L | T | R | I | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | K | V | R | L | A | A | G |
Query Conservation |   |
  |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |
|
|
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | N | V | Y | V | X | A | L | D | F | G | N | G | F | V | K | G | K | I | N | D | E | K | F | V | I | P | S | R | I | G | R | K | T | N | E | N | N | Q | L | K | G | F | V | D | N | K | L | D | V | S | E | F | I | I | N | G | N | N | D | E | V | L | L | F | G | N | D | L | D | K | T | T | N | T | G | K | D | T | A |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  | T | T |  |  |  |  |  |  | S |  |  |  |  |
|
| S | S |
|
| S | S | T | T | T | S |
|
|
|
| S |
|  |  |  |  |  | T | T |
| T | T |
|
|  |  |  | S | T | T |  |  |  |  |
| S |
|
|  |  |
|
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
46 | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 110 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
Query Sequence |   |
L | N | S | E | N | A | L | S | N | E | A | M | E | R | G | W | Q | C | L | R | L | F | A | E | R | L | Q | D | I | P | P | S | Q | I | R | V | V | A | T | A | T | L | R | L | A | V | N | A | G | D | F | I | A | K | A | Q | E | I | L | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
C | P | V | Q | V | I | S |
Query Conservation |   |
  |   |   |   |
|   |
|
|   |
|
|
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|
|
|
|
|   |
|   |
|   |   |   |
|
|   |   |
|   |   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |
|   |   |
|   |
|   |
|
Template Sequence |   |
S | T | N | D | R | Y | D | I | K | S | F | K | D | L | V | E | C | S | I | G | L | L | A | R | E | V | P | E | E | V | V | N | V | V | I | A | T | G | X | P | S | N | E | I | G | T | D | K | Q | A | K | F | E | K | L | L | N | K | S | R | L | I | E | I | D | G | I | A | K | T | I | N | V | K | G | V | K | I | V | A |
Template Known Secondary structure |   |
| S | T | T | G | G | G | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| S | S |  |  |  |  |  |  |  |  |  |  |
| G | G | G | T | T | S |  |  |  |  |  |  |  |  |  |  | S | S |
|  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
  |
  |   |
113 | . | . | . | . | . | . | 120 | . | . | |
|
|
. | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | |
|
. | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
170 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  | . | . |  |  |  |  |  |
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
G | E | E | E | A | R | L | I | Y | Q | . |
. |
. |
G | V | A | H | T | T | G | G | A | D | Q | R | L | V | V | D | I | G | G | A | S | T | E | L | V | T | G | T | G | A | Q | T | T | . |
. |
S | L | F | S | L | S | M | G | C | V | T | W | L | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | Y | F | A | D | R | N | L |
Query Conservation |   |
|   |
|
|
|   |
|   |
|   | . | . | . |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   | . | . |   |   |   |
|
|   |
|
|   |
|
|
|   |
| . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
Template Sequence |   |
Q | P | X | G | T | L | L | D | L | N | X | E | N | G | K | V | F | K | A | F | T | E | G | K | Y | S | V | L | D | F | G | S | G | T | T | I | I | D | T | Y | Q | N | X | K | R | V | E | E | E | S | F | V | I | N | K | G | T | I | D | F | Y | K | R | I | A | S | H | V | S | T | P | R | M | I | E | K | G | L | E | F |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T |  |  | T | T |  |  |
|  |  |  |  | T |
|  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  | T | T |  |  |
| G | G | G |
|  |  |  | S |
|
|  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  | S |
|
|
|
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
  |
  |   |
178 | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | |
. | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | Q | E | N | F | D | A | A | E | K | A | A | R | E | V | L | R | P | V | A | D | E | L | R | Y | . |
H | G | W | K | V | C | V | G | A | S | G | T | V | Q | A | L | Q | E | I | M | M | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |
|
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|
|   |   |
|   |   |   |
|   |   |
Template Sequence |   |
K | D | E | F | Y | K | E | Q | D | S | L | I | E | E | V | X | S | N | F | E | I | T | V | G | N | I | N | S | I | D | R | I | I | V | T | G | G | G | A | N | I | H | F | D | S | L | S | H |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T | S |
| S |  |  |  |  |  | S | T | T |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
263 | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 |
  |