Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	A	G	K	L	P	E	G	W	V	I	A	P	V	S	T	V	T	T	L	I	R	G	V	T	Y	K	K	E	Q	A	I	N	Y	L	K	D	D	Y	L	P	L	I	R	A	N	N	I	Q	N	G	K	F	D	T	T	D	L	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																?		?	?	?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	V	P	K	N	L	V	K	E	S	Q	K	I	S	P	E	D	I	V	I	A	M	S	S	G	S	K	S	V	V	G	K	S	A	H	Q	H	L	P	F	E	C	S	F	G	A	F	C	G	V	L	R	P	E	K	L	I	F	S	G
Secondary structure
SS confidence
Disorder																										?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		F	I	A	H	F	T	K	S	S	L	Y	R	N	K	I	S	S	L	S	A	G	A	N	I	N	N	I	K	P	A	S	F	D	L	I	N	I	P	I	P	P	L	A	E	Q	K	I	I	A	E	K	L	D	T	L	L	A	Q	V	D
Secondary structure
SS confidence
Disorder																		?		?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	T	K	A	R	F	E	Q	I	P	Q	I	L	K	R	F	R	Q	A	V	L	G	G	A	V	N	G	K	L	T	E	K	W	R	N	F	E	P	Q	H	S	V	F	K	K	L	N	F	E	S	I	L	T	E	L	R	N	G	L	S
Secondary structure
SS confidence
Disorder																													?	?	?	?		?	?	?	?	?																		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	K	P	N	E	S	G	V	G	H	P	I	L	R	I	S	S	V	R	A	G	H	V	D	Q	N	D	I	R	F	L	E	C	S	E	S	E	L	N	R	H	K	L	Q	D	G	D	L	L	F	T	R	Y	N	G	S	L	E	F	V
Secondary structure
SS confidence
Disorder		?	?		?	?																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	V	C	G	L	L	K	K	L	Q	H	Q	N	L	L	Y	P	D	K	L	I	R	A	R	L	T	K	D	A	L	P	E	Y	I	E	I	F	F	S	S	P	S	A	R	N	A	M	M	N	C	V	K	T	T	S	G	Q	K	G	I
Secondary structure
SS confidence
Disorder																																																				?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		S	G	K	D	I	K	S	Q	V	V	L	L	P	P	V	K	E	Q	A	E	I	V	R	R	V	E	Q	L	F	A	Y	A	D	T	I	E	K	Q	V	N	N	A	L	A	R	V	N	N	L	T	Q	S	I	L	A	K	A	F	R	G
Secondary structure
SS confidence
Disorder							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.
Sequence		E	L	T	A	Q	W	R	A	E	N	P	D	L	I	S	G	E	N	S	A	A	A	L	L	E	K	I	K	A	E	R	A	A	S	G	G	K	K	A	S	R	K	K	S
Secondary structure
SS confidence
Disorder													?		?	?	?	?																?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2y7c chain A Region: 1 - 464 Aligned: 464 Modelled: 464 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: A: PDB Molecule:type-1 restriction enzyme ecoki specificity protein; PDBTitle: atomic model of the ocr-bound methylase complex from the2 type i restriction-modification enzyme ecoki (m2s1). based3 on fitting into em map 1534. Phyre2 PDB 1yf2 chain A Region: 3 - 425 Aligned: 403 Modelled: 421 Confidence: 100.0% Identity: 15% PDB header:hydrolase regulator Chain: A: PDB Molecule:type i restriction-modification enzyme, s subunit; PDBTitle: three-dimensional structure of dna sequence specificity (s) subunit of2 a type i restriction-modification enzyme and its functional3 implications Phyre2 PDB 3okg chain B Region: 1 - 422 Aligned: 384 Modelled: 422 Confidence: 100.0% Identity: 20% PDB header:dna binding protein Chain: B: PDB Molecule:restriction endonuclease s subunits; PDBTitle: crystal structure of hsds subunit from thermoanaerobacter2 tengcongensis Phyre2 PDB 1ydx chain A Region: 9 - 421 Aligned: 359 Modelled: 377 Confidence: 100.0% Identity: 14% PDB header:dna binding protein Chain: A: PDB Molecule:type i restriction enzyme specificity protein mg438; PDBTitle: crystal structure of type-i restriction-modification system s subunit2 from m. genitalium Phyre2 PDB 1yf2 chain A domain 2 Region: 4 - 212 Aligned: 198 Modelled: 209 Confidence: 99.9% Identity: 22% Fold: DNA methylase specificity domain Superfamily: DNA methylase specificity domain Family: Type I restriction modification DNA specificity domain Phyre2 PDB 1yf2 chain A domain 1 Region: 4 - 213 Aligned: 200 Modelled: 210 Confidence: 99.9% Identity: 21% Fold: DNA methylase specificity domain Superfamily: DNA methylase specificity domain Family: Type I restriction modification DNA specificity domain Phyre2 PDB 1ydx chain A domain 2 Region: 6 - 208 Aligned: 176 Modelled: 188 Confidence: 99.9% Identity: 14% Fold: DNA methylase specificity domain Superfamily: DNA methylase specificity domain Family: Type I restriction modification DNA specificity domain Phyre2 PDB 1ydx chain A domain 1 Region: 7 - 202 Aligned: 173 Modelled: 182 Confidence: 99.8% Identity: 18% Fold: DNA methylase specificity domain Superfamily: DNA methylase specificity domain Family: Type I restriction modification DNA specificity domain Phyre2 PDB 1aqj chain B Region: 222 - 371 Aligned: 142 Modelled: 150 Confidence: 96.8% Identity: 9% PDB header:methyltransferase Chain: B: PDB Molecule:adenine-n6-dna-methyltransferase taqi; PDBTitle: structure of adenine-n6-dna-methyltransferase taqi Phyre2 PDB 1g38 chain A Region: 242 - 371 Aligned: 122 Modelled: 130 Confidence: 96.5% Identity: 9% PDB header:transferase/dna Chain: A: PDB Molecule:modification methylase taqi; PDBTitle: adenine-specific methyltransferase m. taq i/dna complex Phyre2 PDB 3s1s chain A Region: 310 - 419 Aligned: 108 Modelled: 110 Confidence: 91.4% Identity: 14% PDB header:hydrolase, transferase Chain: A: PDB Molecule:restriction endonuclease bpusi; PDBTitle: characterization and crystal structure of the type iig restriction2 endonuclease bpusi Phyre2 PDB 2ih2 chain A domain 2 Region: 234 - 370 Aligned: 128 Modelled: 132 Confidence: 78.3% Identity: 10% Fold: DNA methylase specificity domain Superfamily: DNA methylase specificity domain Family: TaqI C-terminal domain-like Phyre2 PDB 1yiu chain A Region: 2 - 14 Aligned: 13 Modelled: 13 Confidence: 61.7% Identity: 38% PDB header:ligase Chain: A: PDB Molecule:itchy e3 ubiquitin protein ligase; PDBTitle: itch e3 ubiquitin ligase ww3 domain Phyre2 PDB 2kyk chain A Region: 2 - 14 Aligned: 13 Modelled: 13 Confidence: 58.0% Identity: 38% PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog; PDBTitle: the sandwich region between two lmp2a py motif regulates the2 interaction between aip4ww2domain and py motif Phyre2 PDB 2djy chain A Region: 2 - 14 Aligned: 13 Modelled: 13 Confidence: 51.1% Identity: 46% PDB header:ligase/signaling protein Chain: A: PDB Molecule:smad ubiquitination regulatory factor 2; PDBTitle: solution structure of smurf2 ww3 domain-smad7 py peptide2 complex Phyre2 PDB 2jmf chain A Region: 2 - 14 Aligned: 13 Modelled: 13 Confidence: 49.5% Identity: 46% PDB header:ligase/signaling protein Chain: A: PDB Molecule:e3 ubiquitin-protein ligase suppressor of deltex; PDBTitle: solution structure of the su(dx) ww4- notch py peptide2 complex Phyre2 PDB 2ysc chain A Region: 1 - 14 Aligned: 14 Modelled: 14 Confidence: 48.8% Identity: 43% PDB header:protein binding Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family PDBTitle: solution structure of the ww domain from the human amyloid2 beta a4 precursor protein-binding family b member 3, apbb3 Phyre2 PDB 1tk7 chain A domain 2 Region: 2 - 14 Aligned: 13 Modelled: 13 Confidence: 46.7% Identity: 46% Fold: WW domain-like Superfamily: WW domain Family: WW domain Phyre2 PDB 2law chain A Region: 4 - 14 Aligned: 11 Modelled: 11 Confidence: 43.4% Identity: 55% PDB header:signaling protein/transcription Chain: A: PDB Molecule:yorkie homolog; PDBTitle: structure of the second ww domain from human yap in complex with a2 human smad1 derived peptide Phyre2 PDB 2jmf chain A domain 1 Region: 4 - 14 Aligned: 11 Modelled: 11 Confidence: 42.4% Identity: 55% Fold: WW domain-like Superfamily: WW domain Family: WW domain Phyre2 1 c2y7cA_ 2 c1yf2A_ 3 c3okgB_ 4 c1ydxA_ 5 d1yf2a2 6 d1yf2a1 7 d1ydxa2 8 d1ydxa1 9 c1aqjB_ 10 c1g38A_ 11 c3s1sA_ 12 d2ih2a2 13 c1yiuA_ 14 c2kykA_ 15 c2djyA_ 16 c2jmfA_ 17 c2yscA_ 18 d1tk7a2 19 c2lawA_ 20 d2jmfa1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2y7cA_ 100.0 100 PDB header:transferase Chain: A: PDB Molecule:type-1 restriction enzyme ecoki specificity protein; PDBTitle: atomic model of the ocr-bound methylase complex from the2 type i restriction-modification enzyme ecoki (m2s1). based3 on fitting into em map 1534. 2 c1yf2A_ 100.0 15 PDB header:hydrolase regulator Chain: A: PDB Molecule:type i restriction-modification enzyme, s subunit; PDBTitle: three-dimensional structure of dna sequence specificity (s) subunit of2 a type i restriction-modification enzyme and its functional3 implications 3 c3okgB_ 100.0 20 PDB header:dna binding protein Chain: B: PDB Molecule:restriction endonuclease s subunits; PDBTitle: crystal structure of hsds subunit from thermoanaerobacter2 tengcongensis 4 c1ydxA_ 100.0 14 PDB header:dna binding protein Chain: A: PDB Molecule:type i restriction enzyme specificity protein mg438; PDBTitle: crystal structure of type-i restriction-modification system s subunit2 from m. genitalium 5 d1yf2a2 99.9 22 Fold:DNA methylase specificity domain Superfamily:DNA methylase specificity domain Family:Type I restriction modification DNA specificity domain 6 d1yf2a1 99.9 21 Fold:DNA methylase specificity domain Superfamily:DNA methylase specificity domain Family:Type I restriction modification DNA specificity domain 7 d1ydxa2 99.9 14 Fold:DNA methylase specificity domain Superfamily:DNA methylase specificity domain Family:Type I restriction modification DNA specificity domain 8 d1ydxa1 99.8 18 Fold:DNA methylase specificity domain Superfamily:DNA methylase specificity domain Family:Type I restriction modification DNA specificity domain 9 c1aqjB_ 96.8 9 PDB header:methyltransferase Chain: B: PDB Molecule:adenine-n6-dna-methyltransferase taqi; PDBTitle: structure of adenine-n6-dna-methyltransferase taqi 10 c1g38A_ 96.5 9 PDB header:transferase/dna Chain: A: PDB Molecule:modification methylase taqi; PDBTitle: adenine-specific methyltransferase m. taq i/dna complex 11 c3s1sA_ 91.4 14 PDB header:hydrolase, transferase Chain: A: PDB Molecule:restriction endonuclease bpusi; PDBTitle: characterization and crystal structure of the type iig restriction2 endonuclease bpusi 12 d2ih2a2 78.3 10 Fold:DNA methylase specificity domain Superfamily:DNA methylase specificity domain Family:TaqI C-terminal domain-like 13 c1yiuA_ 61.7 38 PDB header:ligase Chain: A: PDB Molecule:itchy e3 ubiquitin protein ligase; PDBTitle: itch e3 ubiquitin ligase ww3 domain 14 c2kykA_ 58.0 38 PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog; PDBTitle: the sandwich region between two lmp2a py motif regulates the2 interaction between aip4ww2domain and py motif 15 c2djyA_ 51.1 46 PDB header:ligase/signaling protein Chain: A: PDB Molecule:smad ubiquitination regulatory factor 2; PDBTitle: solution structure of smurf2 ww3 domain-smad7 py peptide2 complex 16 c2jmfA_ 49.5 46 PDB header:ligase/signaling protein Chain: A: PDB Molecule:e3 ubiquitin-protein ligase suppressor of deltex; PDBTitle: solution structure of the su(dx) ww4- notch py peptide2 complex 17 c2yscA_ 48.8 43 PDB header:protein binding Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family PDBTitle: solution structure of the ww domain from the human amyloid2 beta a4 precursor protein-binding family b member 3, apbb3 18 d1tk7a2 46.7 46 Fold:WW domain-like Superfamily:WW domain Family:WW domain 19 c2lawA_ 43.4 55 PDB header:signaling protein/transcription Chain: A: PDB Molecule:yorkie homolog; PDBTitle: structure of the second ww domain from human yap in complex with a2 human smad1 derived peptide 20 d2jmfa1 42.4 55 Fold:WW domain-like Superfamily:WW domain Family:WW domain 21 d1tk7a1 not modelled 39.9 38 Fold:WW domain-like Superfamily:WW domain Family:WW domain 22 c2dmvA_ not modelled 39.3 31 PDB header:ligase Chain: A: PDB Molecule:itchy homolog e3 ubiquitin protein ligase; PDBTitle: solution structure of the second ww domain of itchy homolog2 e3 ubiquitin protein ligase (itch) 23 c2yshA_ not modelled 39.0 31 PDB header:protein binding Chain: A: PDB Molecule:growth-arrest-specific protein 7; PDBTitle: solution structure of the ww domain from the human growth-2 arrest-specific protein 7, gas-7 24 c2lb0A_ not modelled 38.2 40 PDB header:signaling protein/transcription Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1; PDBTitle: structure of the first ww domain of human smurf1 in complex with a di-2 phosphorylated human smad1 derived peptide 25 c2lazA_ not modelled 38.2 40 PDB header:signaling protein/transcription Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1; PDBTitle: structure of the first ww domain of human smurf1 in complex with a2 mono-phosphorylated human smad1 derived peptide 26 d1seda_ not modelled 36.0 20 Fold:Hypothetical protein YhaI Superfamily:Hypothetical protein YhaI Family:Hypothetical protein YhaI 27 d1gxha_ not modelled 35.9 35 Fold:Acyl carrier protein-like Superfamily:Colicin E immunity proteins Family:Colicin E immunity proteins 28 d2vlqa1 not modelled 35.3 26 Fold:Acyl carrier protein-like Superfamily:Colicin E immunity proteins Family:Colicin E immunity proteins 29 c1pqvS_ not modelled 35.2 20 PDB header:transferase/transcription Chain: S: PDB Molecule:transcription elongation factor s-ii; PDBTitle: rna polymerase ii-tfiis complex 30 d1ayia_ not modelled 34.3 30 Fold:Acyl carrier protein-like Superfamily:Colicin E immunity proteins Family:Colicin E immunity proteins 31 c1wmvA_ not modelled 34.1 43 PDB header:oxidoreductase, apoptosis Chain: A: PDB Molecule:ww domain containing oxidoreductase; PDBTitle: solution structure of the second ww domain of wwox 32 c2ysgA_ not modelled 33.9 38 PDB header:protein binding Chain: A: PDB Molecule:syntaxin-binding protein 4; PDBTitle: solution structure of the ww domain from the human syntaxin-2 binding protein 4 33 c1wr7A_ not modelled 33.7 29 PDB header:ligase Chain: A: PDB Molecule:nedd4-2; PDBTitle: solution structure of the third ww domain of nedd4-2 34 d1pina1 not modelled 33.6 56 Fold:WW domain-like Superfamily:WW domain Family:WW domain 35 c2dwvB_ not modelled 32.9 29 PDB header:protein binding Chain: B: PDB Molecule:salvador homolog 1 protein; PDBTitle: solution structure of the second ww domain from mouse2 salvador homolog 1 protein (mww45) 36 c3l4hA_ not modelled 32.9 38 PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase hecw1; PDBTitle: helical box domain and second ww domain of the human e3 ubiquitin-2 protein ligase hecw1 37 c2l4jA_ not modelled 32.9 70 PDB header:transcription Chain: A: PDB Molecule:yes-associated protein 2 (yap2); PDBTitle: yap ww2 38 c1y1yS_ not modelled 32.5 20 PDB header:transferase/transcription/dna-rna hybrid Chain: S: PDB Molecule:transcription elongation factor s-ii; PDBTitle: rna polymerase ii-tfiis-dna/rna complex 39 c3m9hB_ not modelled 32.2 24 PDB header:chaperone Chain: B: PDB Molecule:proteasome-associated atpase; PDBTitle: crystal structure of the amino terminal coiled coil domain of the2 mycobacterium tuberculosis proteasomal atpase mpa 40 c2no8A_ not modelled 32.1 35 PDB header:immune system Chain: A: PDB Molecule:colicin-e2 immunity protein; PDBTitle: nmr structure analysis of the colicin immuntiy protein im2 41 d1i5hw_ not modelled 30.9 38 Fold:WW domain-like Superfamily:WW domain Family:WW domain 42 c2ysfA_ not modelled 30.7 38 PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog; PDBTitle: solution structure of the fourth ww domain from the human2 e3 ubiquitin-protein ligase itchy homolog, itch 43 d2p0ta1 not modelled 30.7 16 Fold:PSPTO4464-like Superfamily:PSPTO4464-like Family:PSPTO4464-like 44 c2p0tA_ not modelled 30.7 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0307 protein pspto_4464; PDBTitle: structural genomics, the crystal structure of a conserved putative2 protein from pseudomonas syringae pv. tomato str. dc3000 45 c2ysdA_ not modelled 30.0 50 PDB header:protein binding Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz PDBTitle: solution structure of the first ww domain from the human2 membrane-associated guanylate kinase, ww and pdz domain-3 containing protein 1. magi-1 46 c3bc1F_ not modelled 29.9 17 PDB header:signaling protein/transport protein Chain: F: PDB Molecule:synaptotagmin-like protein 2; PDBTitle: crystal structure of the complex rab27a-slp2a 47 d1i8gb_ not modelled 29.2 56 Fold:WW domain-like Superfamily:WW domain Family:WW domain 48 c3p8cE_ not modelled 28.6 16 PDB header:protein binding Chain: E: PDB Molecule:probable protein brick1; PDBTitle: structure and control of the actin regulatory wave complex 49 d2crua1 not modelled 25.9 16 Fold:RuvA C-terminal domain-like Superfamily:Double-stranded DNA-binding domain Family:Double-stranded DNA-binding domain 50 c1yw5A_ not modelled 23.9 38 PDB header:isomerase Chain: A: PDB Molecule:peptidyl prolyl cis/trans isomerase; PDBTitle: peptidyl-prolyl isomerase ess1 from candida albicans 51 c2dmeA_ not modelled 23.4 23 PDB header:metal binding protein Chain: A: PDB Molecule:phd finger protein 3; PDBTitle: solution structure of the tfiis domain ii of human phd2 finger protein 3 52 c2gl2B_ not modelled 22.9 17 PDB header:cell adhesion Chain: B: PDB Molecule:adhesion a; PDBTitle: crystal structure of the tetra muntant (t66g,r67g,f68g,2 y69g) of bacterial adhesin fada 53 c3le4A_ not modelled 22.3 44 PDB header:nuclear protein Chain: A: PDB Molecule:microprocessor complex subunit dgcr8; PDBTitle: crystal structure of the dgcr8 dimerization domain 54 c1tk7A_ not modelled 21.8 38 PDB header:signaling protein Chain: A: PDB Molecule:cg4244-pb; PDBTitle: nmr structure of ww domains (ww3-4) from suppressor of2 deltex 55 c1e0mA_ not modelled 21.7 44 PDB header:de novo protein Chain: A: PDB Molecule:wwprototype; PDBTitle: prototype ww domain 56 c1ymzA_ not modelled 21.4 40 PDB header:unknown function Chain: A: PDB Molecule:cc45; PDBTitle: cc45, an artificial ww domain designed using statistical2 coupling analysis 57 d2f21a1 not modelled 20.6 44 Fold:WW domain-like Superfamily:WW domain Family:WW domain 58 d2itka1 not modelled 20.5 63 Fold:WW domain-like Superfamily:WW domain Family:WW domain 59 c2ysbA_ not modelled 20.4 36 PDB header:protein binding Chain: A: PDB Molecule:salvador homolog 1 protein; PDBTitle: solution structure of the first ww domain from the mouse2 salvador homolog 1 protein (sav1) 60 d1k9ra_ not modelled 20.1 38 Fold:WW domain-like Superfamily:WW domain Family:WW domain 61 c2zajA_ not modelled 19.6 40 PDB header:protein binding Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz PDBTitle: solution structure of the short-isoform of the second ww2 domain from the human membrane-associated guanylate kinase,3 ww and pdz domain-containing protein 1 (magi-1) 62 c1wr4A_ not modelled 18.5 44 PDB header:ligase Chain: A: PDB Molecule:ubiquitin-protein ligase nedd4-2; PDBTitle: solution structure of the second ww domain of nedd4-2 63 c2kq0A_ not modelled 18.4 44 PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase nedd4; PDBTitle: human nedd4 3rd ww domain complex with ebola zaire virus matrix2 protein vp40 derived peptide ilptappeymea 64 d3dlqi1 not modelled 18.0 27 Fold:4-helical cytokines Superfamily:4-helical cytokines Family:Interferons/interleukin-10 (IL-10) 65 c2jv4A_ not modelled 18.0 38 PDB header:isomerase Chain: A: PDB Molecule:peptidyl-prolyl cis/trans isomerase; PDBTitle: structure characterisation of pina ww domain and comparison2 with other group iv ww domains, pin1 and ess1 66 c2ez5W_ not modelled 17.6 23 PDB header:signalling protein,ligase Chain: W: PDB Molecule:e3 ubiquitin-protein ligase nedd4; PDBTitle: solution structure of the dnedd4 ww3* domain- comm lpsy2 peptide complex 67 d1ig4a_ not modelled 17.2 17 Fold:DNA-binding domain Superfamily:DNA-binding domain Family:Methyl-CpG-binding domain, MBD 68 d2ho2a1 not modelled 17.0 36 Fold:WW domain-like Superfamily:WW domain Family:WW domain 69 d1f8ab1 not modelled 16.8 36 Fold:WW domain-like Superfamily:WW domain Family:WW domain 70 c3olmA_ not modelled 15.6 63 PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase rsp5; PDBTitle: structure and function of a ubiquitin binding site within the2 catalytic domain of a hect ubiquitin ligase 71 d1dd5a_ not modelled 14.8 17 Fold:RRF/tRNA synthetase additional domain-like Superfamily:Ribosome recycling factor, RRF Family:Ribosome recycling factor, RRF 72 c2gleA_ not modelled 14.0 7 PDB header:protein binding Chain: A: PDB Molecule:neurabin-1; PDBTitle: solution structure of neurabin sam domain 73 c1bm4A_ not modelled 14.0 41 PDB header:viral protein Chain: A: PDB Molecule:protein (moloney murine leukemia virus capsid); PDBTitle: momlv capsid protein major homology region peptide analog 74 c2fh0A_ not modelled 14.0 13 PDB header:unknown function Chain: A: PDB Molecule:hypothetical 16.0 kda protein in abf2-chl12 PDBTitle: nmr ensemble of the yeast saccharomyces cerevisiae protein2 ymr074cp core region 75 d1ek8a_ not modelled 13.3 20 Fold:RRF/tRNA synthetase additional domain-like Superfamily:Ribosome recycling factor, RRF Family:Ribosome recycling factor, RRF 76 d2ysca1 not modelled 13.1 44 Fold:WW domain-like Superfamily:WW domain Family:WW domain 77 c3uorB_ not modelled 12.6 18 PDB header:sugar binding protein Chain: B: PDB Molecule:abc transporter sugar binding protein; PDBTitle: the structure of the sugar-binding protein male from the phytopathogen2 xanthomonas citri 78 c3kxeD_ not modelled 12.1 13 PDB header:protein binding Chain: D: PDB Molecule:antitoxin protein pard-1; PDBTitle: a conserved mode of protein recognition and binding in a2 pard-pare toxin-antitoxin complex 79 d1wqga1 not modelled 12.0 19 Fold:RRF/tRNA synthetase additional domain-like Superfamily:Ribosome recycling factor, RRF Family:Ribosome recycling factor, RRF 80 c3cqxD_ not modelled 12.0 30 PDB header:chaperone Chain: D: PDB Molecule:bag family molecular chaperone regulator 2; PDBTitle: chaperone complex 81 d1nmva1 not modelled 11.6 46 Fold:WW domain-like Superfamily:WW domain Family:WW domain 82 d1zkea1 not modelled 11.4 12 Fold:ROP-like Superfamily:HP1531-like Family:HP1531-like 83 d1ge9a_ not modelled 11.3 29 Fold:RRF/tRNA synthetase additional domain-like Superfamily:Ribosome recycling factor, RRF Family:Ribosome recycling factor, RRF 84 c2ky8A_ not modelled 11.3 19 PDB header:transcription/dna Chain: A: PDB Molecule:methyl-cpg-binding domain protein 2; PDBTitle: solution structure and dynamic analysis of chicken mbd2 methyl binding2 domain bound to a target methylated dna sequence 85 c2ysiA_ not modelled 11.2 23 PDB header:protein binding Chain: A: PDB Molecule:transcription elongation regulator 1; PDBTitle: solution structure of the first ww domain from the mouse2 transcription elongation regulator 1, transcription factor3 ca150 86 c2ejxA_ not modelled 10.8 36 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:st0812; PDBTitle: crystal structure of the hypothetical protein st0812 from2 sulfolobus tokodaii 87 d1eh1a_ not modelled 10.8 14 Fold:RRF/tRNA synthetase additional domain-like Superfamily:Ribosome recycling factor, RRF Family:Ribosome recycling factor, RRF 88 c1f8aB_ not modelled 10.6 42 PDB header:isomerase Chain: B: PDB Molecule:peptidyl-prolyl cis-trans isomerase nima- PDBTitle: structural basis for the phosphoserine-proline recognition2 by group iv ww domains 89 d1is1a_ not modelled 10.4 17 Fold:RRF/tRNA synthetase additional domain-like Superfamily:Ribosome recycling factor, RRF Family:Ribosome recycling factor, RRF 90 d2gsva1 not modelled 10.0 21 Fold:Open three-helical up-and-down bundle Superfamily:YvfG-like Family:YvfG-like 91 c1lypA_ not modelled 9.4 17 PDB header:lipopolysaccharide-binding protein Chain: A: PDB Molecule:cap18; PDBTitle: the solution structure of the active domain of cap18: a2 lipopolysaccharide binding protein from rabbit leukocytes 92 d2clyb1 not modelled 9.3 12 Fold:ATP synthase D chain-like Superfamily:ATP synthase D chain-like Family:ATP synthase D chain-like 93 c3npfB_ not modelled 9.2 13 PDB header:hydrolase Chain: B: PDB Molecule:putative dipeptidyl-peptidase vi; PDBTitle: crystal structure of a putative dipeptidyl-peptidase vi (bacova_00612)2 from bacteroides ovatus at 1.72 a resolution 94 d2evra2 not modelled 9.2 13 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:NlpC/P60 95 d2nrka1 not modelled 9.2 11 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:GrpB-like 96 c3qufB_ not modelled 9.0 17 PDB header:transport protein Chain: B: PDB Molecule:extracellular solute-binding protein, family 1; PDBTitle: the structure of a family 1 extracellular solute-binding protein from2 bifidobacterium longum subsp. infantis 97 c2oarA_ not modelled 8.9 16 PDB header:membrane protein Chain: A: PDB Molecule:large-conductance mechanosensitive channel; PDBTitle: mechanosensitive channel of large conductance (mscl) 98 c3pmdA_ not modelled 8.9 29 PDB header:lipid binding protein Chain: A: PDB Molecule:conserved domain protein; PDBTitle: crystal structure of the sporulation inhibitor pxo1-118 from bacillus2 anthracis 99 c2xzmW_ not modelled 8.7 14 PDB header:ribosome Chain: W: PDB Molecule:40s ribosomal protein s4; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 1

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0