Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	N	F	K	H	L	P	E	P	F	R	I	R	V	I	E	P	V	K	R	T	T	R	A	Y	R	E	E	A	I	I	K	S	G	M	N	P	F	L	L	D	S	E	D	V	F	I	D	L	L	T	D	S	G	T	G	A	V	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?													?	?	?	?	?																																			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	S	M	Q	A	A	M	M	R	G	D	E	A	Y	S	G	S	R	S	Y	Y	A	L	A	E	S	V	K	N	I	F	G	Y	Q	Y	T	I	P	T	H	Q	G	R	G	A	E	Q	I	Y	I	P	V	L	I	K	K	R	E	Q	E
Secondary structure
SS confidence
Disorder												?	?			?																																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		K	G	L	D	R	S	K	M	V	A	F	S	N	Y	F	F	D	T	T	Q	G	H	S	Q	I	N	G	C	T	V	R	N	V	Y	I	K	E	A	F	D	T	G	V	R	Y	D	F	K	G	N	F	D	L	E	G	L	E	R	G	I
Secondary structure
SS confidence
Disorder																																						?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	E	V	G	P	N	N	V	P	Y	I	V	A	T	I	T	S	N	S	A	G	G	Q	P	V	S	L	A	N	L	K	A	M	Y	S	I	A	K	K	Y	D	I	P	V	V	M	D	S	A	R	F	A	E	N	A	Y	F	I	K	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		R	E	A	E	Y	K	D	W	T	I	E	Q	I	T	R	E	T	Y	K	Y	A	D	M	L	A	M	S	A	K	K	D	A	M	V	P	M	G	G	L	L	C	M	K	D	D	S	F	F	D	V	Y	T	E	C	R	T	L	C	V	V
Secondary structure
SS confidence
Disorder			?		?	?																									?	?																										?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		Q	E	G	F	P	T	Y	G	G	L	E	G	G	A	M	E	R	L	A	V	G	L	Y	D	G	M	N	L	D	W	L	A	Y	R	I	A	Q	V	Q	Y	L	V	D	G	L	E	E	I	G	V	V	C	Q	Q	A	G	G	H	A	A
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		F	V	D	A	G	K	L	L	P	H	I	P	A	D	Q	F	P	A	Q	A	L	A	C	E	L	Y	K	V	A	G	I	R	A	V	E	I	G	S	F	L	L	G	R	D	P	K	T	G	K	Q	L	P	C	P	A	E	L	L	R	L
Secondary structure
SS confidence
Disorder																																															?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.
Sequence		T	I	P	R	A	T	Y	T	Q	T	H	M	D	F	I	I	E	A	F	K	H	V	K	E	N	A	A	N	I	K	G	L	T	F	T	Y	E	P	K	V	L	R	H	F	T	A	K	L	K	E	V
Secondary structure
SS confidence
Disorder					?	?																											?																		?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2v1p chain A domain 1 Region: 5 - 471 Aligned: 465 Modelled: 467 Confidence: 100.0% Identity: 100% Fold: PLP-dependent transferase-like Superfamily: PLP-dependent transferases Family: Beta-eliminating lyases Phyre2 PDB 1ax4 chain A Region: 5 - 471 Aligned: 462 Modelled: 467 Confidence: 100.0% Identity: 52% Fold: PLP-dependent transferase-like Superfamily: PLP-dependent transferases Family: Beta-eliminating lyases Phyre2 PDB 1c7g chain A Region: 4 - 471 Aligned: 455 Modelled: 468 Confidence: 100.0% Identity: 44% Fold: PLP-dependent transferase-like Superfamily: PLP-dependent transferases Family: Beta-eliminating lyases Phyre2 PDB 1tpl chain A Region: 4 - 471 Aligned: 425 Modelled: 434 Confidence: 100.0% Identity: 44% Fold: PLP-dependent transferase-like Superfamily: PLP-dependent transferases Family: Beta-eliminating lyases Phyre2 PDB 1m6s chain A Region: 47 - 446 Aligned: 334 Modelled: 343 Confidence: 100.0% Identity: 20% Fold: PLP-dependent transferase-like Superfamily: PLP-dependent transferases Family: AAT-like Phyre2 PDB 3h7f chain B Region: 40 - 448 Aligned: 336 Modelled: 387 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:serine hydroxymethyltransferase 1; PDBTitle: crystal structure of serine hydroxymethyltransferase from2 mycobacterium tuberculosis Phyre2 PDB 3n5m chain D Region: 4 - 445 Aligned: 402 Modelled: 426 Confidence: 100.0% Identity: 12% PDB header:transferase Chain: D: PDB Molecule:adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PDBTitle: crystals structure of a bacillus anthracis aminotransferase Phyre2 PDB 1eji chain A Region: 24 - 457 Aligned: 364 Modelled: 406 Confidence: 100.0% Identity: 17% Fold: PLP-dependent transferase-like Superfamily: PLP-dependent transferases Family: GABA-aminotransferase-like Phyre2 PDB 1bj4 chain A Region: 40 - 450 Aligned: 352 Modelled: 387 Confidence: 100.0% Identity: 16% Fold: PLP-dependent transferase-like Superfamily: PLP-dependent transferases Family: GABA-aminotransferase-like Phyre2 PDB 1wyu chain B domain 1 Region: 81 - 449 Aligned: 317 Modelled: 332 Confidence: 100.0% Identity: 17% Fold: PLP-dependent transferase-like Superfamily: PLP-dependent transferases Family: Glycine dehydrogenase subunits (GDC-P) Phyre2 PDB 3hmu chain A Region: 1 - 448 Aligned: 405 Modelled: 414 Confidence: 100.0% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:aminotransferase, class iii; PDBTitle: crystal structure of a class iii aminotransferase from2 silicibacter pomeroyi Phyre2 PDB 1zod chain A domain 1 Region: 1 - 446 Aligned: 393 Modelled: 421 Confidence: 100.0% Identity: 15% Fold: PLP-dependent transferase-like Superfamily: PLP-dependent transferases Family: GABA-aminotransferase-like Phyre2 PDB 3a8u chain X Region: 8 - 445 Aligned: 392 Modelled: 393 Confidence: 100.0% Identity: 14% PDB header:transferase Chain: X: PDB Molecule:omega-amino acid--pyruvate aminotransferase; PDBTitle: crystal structure of omega-amino acid:pyruvate aminotransferase Phyre2 PDB 1rv3 chain A Region: 57 - 458 Aligned: 355 Modelled: 378 Confidence: 100.0% Identity: 16% Fold: PLP-dependent transferase-like Superfamily: PLP-dependent transferases Family: GABA-aminotransferase-like Phyre2 PDB 3n0l chain A Region: 57 - 450 Aligned: 318 Modelled: 349 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:serine hydroxymethyltransferase; PDBTitle: crystal structure of serine hydroxymethyltransferase from2 campylobacter jejuni Phyre2 PDB 3fcr chain A Region: 8 - 445 Aligned: 400 Modelled: 410 Confidence: 100.0% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:putative aminotransferase; PDBTitle: crystal structure of putative aminotransferase (yp_614685.1) from2 silicibacter sp. tm1040 at 1.80 a resolution Phyre2 PDB 3ruy chain B Region: 8 - 443 Aligned: 367 Modelled: 403 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:ornithine aminotransferase; PDBTitle: crystal structure of the ornithine-oxo acid transaminase rocd from2 bacillus anthracis Phyre2 PDB 2byl chain A domain 1 Region: 8 - 445 Aligned: 375 Modelled: 405 Confidence: 100.0% Identity: 12% Fold: PLP-dependent transferase-like Superfamily: PLP-dependent transferases Family: GABA-aminotransferase-like Phyre2 PDB 3i5t chain B Region: 1 - 452 Aligned: 402 Modelled: 407 Confidence: 100.0% Identity: 14% PDB header:transferase Chain: B: PDB Molecule:aminotransferase; PDBTitle: crystal structure of aminotransferase prk07036 from rhodobacter2 sphaeroides kd131 Phyre2 PDB 1oat chain B Region: 8 - 445 Aligned: 375 Modelled: 405 Confidence: 100.0% Identity: 12% PDB header:aminotransferase Chain: B: PDB Molecule:ornithine aminotransferase; PDBTitle: ornithine aminotransferase Phyre2 1 d2v1pa1 2 d1ax4a_ 3 d1c7ga_ 4 d1tpla_ 5 d1m6sa_ 6 c3h7fB_ 7 c3n5mD_ 8 d1ejia_ 9 d1bj4a_ 10 d1wyub1 11 c3hmuA_ 12 d1zoda1 13 c3a8uX_ 14 d1rv3a_ 15 c3n0lA_ 16 c3fcrA_ 17 c3ruyB_ 18 d2byla1 19 c3i5tB_ 20 c1oatB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404