Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	Y	N	G	L	N	N	M	F	F	P	L	C	L	I	N	D	N	H	S	V	T	S	P	S	H	T	K	K	T	K	S	D	N	Y	S	K	H	H	K	N	T	L	I	D	N	K	A	L	S	L	F	K	M	D	D	H	E	K
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?															?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	I	G	L	I	Q	K	M	K	R	I	Y	D	S	L	P	S	G	K	I	T	K	E	T	D	R	K	I	H	K	Y	F	I	D	I	A	S	H	A	N	N	K	C	D	D	R	I	T	R	R	V	Y	L	N	K	D	K	E	V	S
Secondary structure
SS confidence
Disorder														?	?	?	?	?	?	?			?																									?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	K	V	V	Y	F	I	N	N	V	T	V	H	N	N	T	I	E	I	P	Q	T	V	N	G	G	Y	D	F	S	H	L	S	L	K	G	I	V	I	K	D	E	D	L	S	N	S	N	F	A	G	C	R	L	Q	N	A	I	F	Q
Secondary structure
SS confidence
Disorder				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	C	N	M	Y	K	T	N	F	N	F	A	I	M	E	K	I	L	F	D	N	C	I	L	D	D	S	N	F	A	Q	I	K	M	T	D	G	T	L	N	S	C	S	A	M	H	V	Q	F	Y	N	A	T	M	N	R	A	N	I	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		N	T	F	L	D	Y	S	N	F	Y	M	A	Y	M	A	E	V	N	L	Y	K	V	I	A	P	Y	I	N	L	F	R	A	D	L	S	F	S	K	L	D	L	I	N	F	E	H	A	D	L	S	R	V	N	L	N	K	A	T	L	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		N	I	N	L	I	D	S	K	L	F	F	T	R	L	T	N	T	F	L	E	M	V	I	C	T	D	S	N	M	A	N	V	N	F	N	N	A	N	L	S	N	C	H	F	N	C	S	V	L	T	K	A	W	M	F	N	I	R	L	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		R	V	N	F	D	E	A	S	V	Q	G	M	G	I	T	I	L	R	G	E	E	N	I	S	I	N	S	D	I	L	V	T	L	Q	K	F	F	E	E	D	C	A	T	H	T	G	M	S	Q	T	E	D	N	L	H	A	V	A	M	K
Secondary structure
SS confidence
Disorder																																								?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430
Sequence		I	T	A	D	I	M	Q	D	A	D
Secondary structure
SS confidence
Disorder								?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3du1 chain X Region: 139 - 370 Aligned: 230 Modelled: 232 Confidence: 100.0% Identity: 16% PDB header:structural protein Chain: X: PDB Molecule:all3740 protein; PDBTitle: the 2.0 angstrom resolution crystal structure of hetl, a pentapeptide2 repeat protein involved in heterocyst differentiation regulation from3 the cyanobacterium nostoc sp. strain pcc 7120 Phyre2 PDB 2xt4 chain B Region: 149 - 340 Aligned: 192 Modelled: 192 Confidence: 100.0% Identity: 15% PDB header:cell cycle Chain: B: PDB Molecule:mcbg-like protein; PDBTitle: structure of the pentapeptide repeat protein albg, a2 resistance factor for the topoisomerase poison albicidin. Phyre2 PDB 3pss chain B Region: 164 - 370 Aligned: 206 Modelled: 207 Confidence: 100.0% Identity: 13% PDB header:cell cycle Chain: B: PDB Molecule:qnr; PDBTitle: crystal structure of ahqnr, the qnr protein from aeromonas hydrophila2 (p21 crystal form) Phyre2 PDB 2xtw chain B Region: 151 - 359 Aligned: 208 Modelled: 209 Confidence: 100.0% Identity: 14% PDB header:cell cycle Chain: B: PDB Molecule:qnrb1; PDBTitle: structure of qnrb1 (full length), a plasmid-mediated2 fluoroquinolone resistance protein Phyre2 PDB 2xt4 chain A Region: 153 - 359 Aligned: 182 Modelled: 182 Confidence: 100.0% Identity: 16% PDB header:cell cycle Chain: A: PDB Molecule:mcbg-like protein; PDBTitle: structure of the pentapeptide repeat protein albg, a2 resistance factor for the topoisomerase poison albicidin. Phyre2 PDB 3nb2 chain B Region: 145 - 371 Aligned: 176 Modelled: 176 Confidence: 100.0% Identity: 14% PDB header:ligase Chain: B: PDB Molecule:secreted effector protein; PDBTitle: crystal structure of e. coli o157:h7 effector protein nlel Phyre2 PDB 2j8k chain A Region: 151 - 326 Aligned: 176 Modelled: 176 Confidence: 99.9% Identity: 19% PDB header:toxin Chain: A: PDB Molecule:np275-np276; PDBTitle: structure of the fusion of np275 and np276, pentapeptide2 repeat proteins from nostoc punctiforme Phyre2 PDB 2bm5 chain A domain 1 Region: 158 - 371 Aligned: 179 Modelled: 179 Confidence: 99.9% Identity: 15% Fold: Single-stranded right-handed beta-helix Superfamily: Pentapeptide repeat-like Family: Pentapeptide repeats Phyre2 PDB 2w7z chain B Region: 164 - 360 Aligned: 187 Modelled: 197 Confidence: 99.9% Identity: 18% PDB header:inhibitor Chain: B: PDB Molecule:pentapeptide repeat family protein; PDBTitle: structure of the pentapeptide repeat protein efsqnr, a dna2 gyrase inhibitor. free amines modified by cyclic3 pentylation with glutaraldehyde. Phyre2 PDB 2j8k chain A domain 1 Region: 139 - 306 Aligned: 168 Modelled: 168 Confidence: 99.9% Identity: 23% Fold: Single-stranded right-handed beta-helix Superfamily: Pentapeptide repeat-like Family: Pentapeptide repeats Phyre2 PDB 2o6w chain A Region: 148 - 290 Aligned: 142 Modelled: 143 Confidence: 99.9% Identity: 14% PDB header:unknown function Chain: A: PDB Molecule:repeat five residue (rfr) protein or PDBTitle: crystal structure of a pentapeptide repeat protein (rfr23)2 from the cyanobacterium cyanothece 51142 Phyre2 PDB 3n90 chain A Region: 145 - 309 Aligned: 140 Modelled: 141 Confidence: 99.9% Identity: 16% PDB header:unknown function Chain: A: PDB Molecule:thylakoid lumenal 15 kda protein 1, chloroplastic; PDBTitle: the 1.7 angstrom resolution crystal structure of at2g44920, a2 pentapeptide repeat protein from arabidopsis thaliana thylakoid3 lumen. Phyre2 PDB 2g0y chain A Region: 266 - 395 Aligned: 130 Modelled: 130 Confidence: 99.8% Identity: 11% PDB header:unknown function Chain: A: PDB Molecule:pentapeptide repeat protein; PDBTitle: crystal structure of a lumenal pentapeptide repeat protein from2 cyanothece sp 51142 at 2.3 angstrom resolution. tetragonal crystal3 form Phyre2 PDB 2qza chain A Region: 152 - 421 Aligned: 208 Modelled: 217 Confidence: 99.8% Identity: 14% PDB header:ligase Chain: A: PDB Molecule:secreted effector protein; PDBTitle: crystal structure of salmonella effector protein sopa Phyre2 PDB 2j8i chain B Region: 261 - 374 Aligned: 114 Modelled: 114 Confidence: 99.8% Identity: 13% PDB header:toxin Chain: B: PDB Molecule:np275; PDBTitle: structure of np275, a pentapeptide repeat protein from2 nostoc punctiforme Phyre2 PDB 2f3l chain A domain 1 Region: 262 - 389 Aligned: 128 Modelled: 128 Confidence: 99.8% Identity: 17% Fold: Single-stranded right-handed beta-helix Superfamily: Pentapeptide repeat-like Family: Pentapeptide repeats Phyre2 PDB 2j8i chain A domain 1 Region: 139 - 230 Aligned: 92 Modelled: 92 Confidence: 99.7% Identity: 18% Fold: Single-stranded right-handed beta-helix Superfamily: Pentapeptide repeat-like Family: Pentapeptide repeats Phyre2 PDB 2y0s chain Q Region: 62 - 90 Aligned: 29 Modelled: 29 Confidence: 26.4% Identity: 31% PDB header:transferase Chain: Q: PDB Molecule:rna polymerase subunit 13; PDBTitle: crystal structure of sulfolobus shibatae rna polymerase in2 p21 space group Phyre2 PDB 2y0s chain J Region: 62 - 90 Aligned: 29 Modelled: 29 Confidence: 26.4% Identity: 31% PDB header:transferase Chain: J: PDB Molecule:rna polymerase subunit 13; PDBTitle: crystal structure of sulfolobus shibatae rna polymerase in2 p21 space group Phyre2 1 c3du1X_ 2 c2xt4B_ 3 c3pssB_ 4 c2xtwB_ 5 c2xt4A_ 6 c3nb2B_ 7 c2j8kA_ 8 d2bm5a1 9 c2w7zB_ 10 d2j8ka1 11 c2o6wA_ 12 c3n90A_ 13 c2g0yA_ 14 c2qzaA_ 15 c2j8iB_ 16 d2f3la1 17 d2j8ia1 18 c2y0sQ_ 19 c2y0sJ_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3du1X_ 100.0 16 PDB header:structural protein Chain: X: PDB Molecule:all3740 protein; PDBTitle: the 2.0 angstrom resolution crystal structure of hetl, a pentapeptide2 repeat protein involved in heterocyst differentiation regulation from3 the cyanobacterium nostoc sp. strain pcc 7120 2 c2xt4B_ 100.0 15 PDB header:cell cycle Chain: B: PDB Molecule:mcbg-like protein; PDBTitle: structure of the pentapeptide repeat protein albg, a2 resistance factor for the topoisomerase poison albicidin. 3 c3pssB_ 100.0 13 PDB header:cell cycle Chain: B: PDB Molecule:qnr; PDBTitle: crystal structure of ahqnr, the qnr protein from aeromonas hydrophila2 (p21 crystal form) 4 c2xtwB_ 100.0 14 PDB header:cell cycle Chain: B: PDB Molecule:qnrb1; PDBTitle: structure of qnrb1 (full length), a plasmid-mediated2 fluoroquinolone resistance protein 5 c2xt4A_ 100.0 16 PDB header:cell cycle Chain: A: PDB Molecule:mcbg-like protein; PDBTitle: structure of the pentapeptide repeat protein albg, a2 resistance factor for the topoisomerase poison albicidin. 6 c3nb2B_ 100.0 14 PDB header:ligase Chain: B: PDB Molecule:secreted effector protein; PDBTitle: crystal structure of e. coli o157:h7 effector protein nlel 7 c2j8kA_ 99.9 19 PDB header:toxin Chain: A: PDB Molecule:np275-np276; PDBTitle: structure of the fusion of np275 and np276, pentapeptide2 repeat proteins from nostoc punctiforme 8 d2bm5a1 99.9 15 Fold:Single-stranded right-handed beta-helix Superfamily:Pentapeptide repeat-like Family:Pentapeptide repeats 9 c2w7zB_ 99.9 18 PDB header:inhibitor Chain: B: PDB Molecule:pentapeptide repeat family protein; PDBTitle: structure of the pentapeptide repeat protein efsqnr, a dna2 gyrase inhibitor. free amines modified by cyclic3 pentylation with glutaraldehyde. 10 d2j8ka1 99.9 23 Fold:Single-stranded right-handed beta-helix Superfamily:Pentapeptide repeat-like Family:Pentapeptide repeats 11 c2o6wA_ 99.9 14 PDB header:unknown function Chain: A: PDB Molecule:repeat five residue (rfr) protein or PDBTitle: crystal structure of a pentapeptide repeat protein (rfr23)2 from the cyanobacterium cyanothece 51142 12 c3n90A_ 99.9 16 PDB header:unknown function Chain: A: PDB Molecule:thylakoid lumenal 15 kda protein 1, chloroplastic; PDBTitle: the 1.7 angstrom resolution crystal structure of at2g44920, a2 pentapeptide repeat protein from arabidopsis thaliana thylakoid3 lumen. 13 c2g0yA_ 99.8 11 PDB header:unknown function Chain: A: PDB Molecule:pentapeptide repeat protein; PDBTitle: crystal structure of a lumenal pentapeptide repeat protein from2 cyanothece sp 51142 at 2.3 angstrom resolution. tetragonal crystal3 form 14 c2qzaA_ 99.8 14 PDB header:ligase Chain: A: PDB Molecule:secreted effector protein; PDBTitle: crystal structure of salmonella effector protein sopa 15 c2j8iB_ 99.8 13 PDB header:toxin Chain: B: PDB Molecule:np275; PDBTitle: structure of np275, a pentapeptide repeat protein from2 nostoc punctiforme 16 d2f3la1 99.8 17 Fold:Single-stranded right-handed beta-helix Superfamily:Pentapeptide repeat-like Family:Pentapeptide repeats 17 d2j8ia1 99.7 18 Fold:Single-stranded right-handed beta-helix Superfamily:Pentapeptide repeat-like Family:Pentapeptide repeats 18 c2y0sQ_ 26.4 31 PDB header:transferase Chain: Q: PDB Molecule:rna polymerase subunit 13; PDBTitle: crystal structure of sulfolobus shibatae rna polymerase in2 p21 space group 19 c2y0sJ_ 26.4 31 PDB header:transferase Chain: J: PDB Molecule:rna polymerase subunit 13; PDBTitle: crystal structure of sulfolobus shibatae rna polymerase in2 p21 space group

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0