Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	A	Y	W	L	A	Q	G	V	G	V	I	A	F	L	I	G	I	T	T	F	F	N	R	D	E	R	R	F	K	K	Q	L	S	V	Y	S	A	V	I	G	V	H	F	F	L	L	G	T	Y	P	A	G	A	S	A	I	L	N
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	I	R	T	L	I	T	L	R	T	R	S	L	W	V	M	A	I	F	I	V	L	T	G	G	I	G	L	A	K	F	H	H	P	V	E	L	L	P	V	I	G	T	I	V	S	T	W	A	L	F	C	C	K	G	L	T	M	R	C
Secondary structure
SS confidence
Disorder																																																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	M	W	F	S	T	C	C	W	V	I	H	N	F	W	A	G	S	I	G	G	T	M	I	E	G	S	F	L	L	M	N	G	L	N	I	I	R	F	W	R	M	Q	K	R	G	I	D	P	F	K	V	E	K	T	P	S	A	V	D
Secondary structure
SS confidence
Disorder																																														?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.
Sequence		E	R	G
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2dch chain X Region: 158 - 178 Aligned: 21 Modelled: 21 Confidence: 14.0% Identity: 38% PDB header:hydrolase Chain: X: PDB Molecule:putative homing endonuclease; PDBTitle: crystal structure of archaeal intron-encoded homing endonuclease i-2 tsp061i Phyre2 PDB 1sfu chain A Region: 159 - 177 Aligned: 19 Modelled: 19 Confidence: 10.0% Identity: 16% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Z-DNA binding domain Phyre2 PDB 3mku chain A Region: 94 - 175 Aligned: 76 Modelled: 82 Confidence: 7.7% Identity: 21% PDB header:transport protein Chain: A: PDB Molecule:multi antimicrobial extrusion protein (na(+)/drug PDBTitle: structure of a cation-bound multidrug and toxin compound extrusion2 (mate) transporter Phyre2 PDB 3lj4 chain I Region: 172 - 183 Aligned: 12 Modelled: 12 Confidence: 7.1% Identity: 33% PDB header:viral protein Chain: I: PDB Molecule:portal protein; PDBTitle: bacteriophage p22 portal protein bound to middle tail factor gp4. this2 file contain the first biological assembly Phyre2 PDB 1xrd chain A domain 1 Region: 25 - 49 Aligned: 25 Modelled: 25 Confidence: 6.1% Identity: 16% Fold: Light-harvesting complex subunits Superfamily: Light-harvesting complex subunits Family: Light-harvesting complex subunits Phyre2 PDB 1xmk chain A domain 1 Region: 159 - 176 Aligned: 18 Modelled: 18 Confidence: 5.4% Identity: 17% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Z-DNA binding domain Phyre2 PDB 1v54 chain F Region: 162 - 182 Aligned: 21 Modelled: 21 Confidence: 5.3% Identity: 33% Fold: Rubredoxin-like Superfamily: Rubredoxin-like Family: Cytochrome c oxidase Subunit F Phyre2 PDB 3be3 chain A Region: 160 - 181 Aligned: 22 Modelled: 22 Confidence: 5.3% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a protein belonging to pfam duf16532 from bordetella bronchiseptica Phyre2 1 c2dchX_ 2 d1sfua_ 3 c3mkuA_ 4 c3lj4i_ 5 d1xrda1 6 d1xmka1 7 d1v54f_ 8 c3be3A_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2dchX_ 14.0 38 PDB header:hydrolase Chain: X: PDB Molecule:putative homing endonuclease; PDBTitle: crystal structure of archaeal intron-encoded homing endonuclease i-2 tsp061i 2 d1sfua_ 10.0 16 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Z-DNA binding domain 3 c3mkuA_ 7.7 21 PDB header:transport protein Chain: A: PDB Molecule:multi antimicrobial extrusion protein (na(+)/drug PDBTitle: structure of a cation-bound multidrug and toxin compound extrusion2 (mate) transporter 4 c3lj4i_ 7.1 33 PDB header:viral protein Chain: I: PDB Molecule:portal protein; PDBTitle: bacteriophage p22 portal protein bound to middle tail factor gp4. this2 file contain the first biological assembly 5 d1xrda1 6.1 16 Fold:Light-harvesting complex subunits Superfamily:Light-harvesting complex subunits Family:Light-harvesting complex subunits 6 d1xmka1 5.4 17 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Z-DNA binding domain 7 d1v54f_ 5.3 33 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Cytochrome c oxidase Subunit F 8 c3be3A_ 5.3 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a protein belonging to pfam duf16532 from bordetella bronchiseptica

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0