Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	T	R	V	A	N	F	C	R	K	V	L	S	R	E	E	S	E	A	E	Q	A	V	A	R	P	Q	V	T	V	I	P	R	E	Q	H	A	I	S	R	K	D	I	S	E	N	A	L	K	V	M	Y	R	L	N	K	A	G	Y
Secondary structure
SS confidence
Disorder		?	?	?										?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?					?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	A	W	L	V	G	G	G	V	R	D	L	L	L	G	K	K	P	K	D	F	D	V	T	T	N	A	T	P	E	Q	V	R	K	L	F	R	N	C	R	L	V	G	R	R	F	R	L	A	H	V	M	F	G	P	E	I	I	E	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	T	F	R	G	H	H	E	G	N	V	S	D	R	T	T	S	Q	R	G	Q	N	G	M	L	L	R	D	N	I	F	G	S	I	E	E	D	A	Q	R	R	D	F	T	I	N	S	L	Y	Y	S	V	A	D	F	T	V	R	D	Y
Secondary structure
SS confidence
Disorder																		?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	G	G	M	K	D	L	K	D	G	V	I	R	L	I	G	N	P	E	T	R	Y	R	E	D	P	V	R	M	L	R	A	V	R	F	A	A	K	L	G	M	R	I	S	P	E	T	A	E	P	I	P	R	L	A	T	L	L	N	D
Secondary structure
SS confidence
Disorder																																																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		I	P	P	A	R	L	F	E	E	S	L	K	L	L	Q	A	G	Y	G	Y	E	T	Y	K	L	L	C	E	Y	H	L	F	Q	P	L	F	P	T	I	T	R	Y	F	T	E	N	G	D	S	P	M	E	R	I	I	E	Q	V	L	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		N	T	D	T	R	I	H	N	D	M	R	V	N	P	A	F	L	F	A	A	M	F	W	Y	P	L	L	E	T	A	Q	K	I	A	Q	E	S	G	L	T	Y	H	D	A	F	A	L	A	M	N	D	V	L	D	E	A	C	R	S	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		A	I	P	K	R	L	T	T	L	T	R	D	I	W	Q	L	Q	L	R	M	S	R	R	Q	G	K	R	A	W	K	L	L	E	H	P	K	F	R	A	A	Y	D	L	L	A	L	R	A	E	V	E	R	N	A	E	L	Q	R	L	V
Secondary structure
SS confidence
Disorder																						?	?	?	?	?	?																								?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.
Sequence		K	W	W	G	E	F	Q	V	S	A	P	P	D	Q	K	G	M	L	N	E	L	D	E	E	P	S	P	R	R	R	T	R	R	P	R	K	R	A	P	R	R	E	G	T	A
Secondary structure
SS confidence
Disorder									?	?	?										?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3aqn chain A Region: 28 - 438 Aligned: 388 Modelled: 388 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: A: PDB Molecule:poly(a) polymerase; PDBTitle: complex structure of bacterial protein (apo form ii) Phyre2 PDB 1miy chain B Region: 46 - 464 Aligned: 360 Modelled: 364 Confidence: 100.0% Identity: 28% PDB header:translation, transferase Chain: B: PDB Molecule:trna cca-adding enzyme; PDBTitle: crystal structure of bacillus stearothermophilus cca-adding enzyme in2 complex with ctp Phyre2 PDB 1vfg chain B Region: 51 - 447 Aligned: 342 Modelled: 354 Confidence: 100.0% Identity: 24% PDB header:transferase/rna Chain: B: PDB Molecule:poly a polymerase; PDBTitle: crystal structure of trna nucleotidyltransferase complexed2 with a primer trna and an incoming atp analog Phyre2 PDB 3h37 chain B Region: 42 - 464 Aligned: 368 Modelled: 360 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: B: PDB Molecule:trna nucleotidyl transferase-related protein; PDBTitle: the structure of cca-adding enzyme apo form i Phyre2 PDB 1ou5 chain A Region: 41 - 422 Aligned: 318 Modelled: 321 Confidence: 100.0% Identity: 26% PDB header:translation, transferase Chain: A: PDB Molecule:trna cca-adding enzyme; PDBTitle: crystal structure of human cca-adding enzyme Phyre2 PDB 1miw chain A domain 2 Region: 46 - 190 Aligned: 125 Modelled: 126 Confidence: 100.0% Identity: 38% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Poly A polymerase head domain-like Phyre2 PDB 1ou5 chain A domain 2 Region: 41 - 190 Aligned: 125 Modelled: 126 Confidence: 100.0% Identity: 35% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Poly A polymerase head domain-like Phyre2 PDB 1vfg chain A domain 2 Region: 51 - 190 Aligned: 119 Modelled: 119 Confidence: 100.0% Identity: 40% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Poly A polymerase head domain-like Phyre2 PDB 1miw chain A domain 1 Region: 191 - 464 Aligned: 234 Modelled: 238 Confidence: 100.0% Identity: 21% Fold: Poly A polymerase C-terminal region-like Superfamily: Poly A polymerase C-terminal region-like Family: Poly A polymerase C-terminal region-like Phyre2 PDB 1vfg chain A domain 1 Region: 191 - 427 Aligned: 203 Modelled: 215 Confidence: 100.0% Identity: 18% Fold: Poly A polymerase C-terminal region-like Superfamily: Poly A polymerase C-terminal region-like Family: Poly A polymerase C-terminal region-like Phyre2 PDB 1ou5 chain A domain 1 Region: 191 - 422 Aligned: 193 Modelled: 208 Confidence: 100.0% Identity: 19% Fold: Poly A polymerase C-terminal region-like Superfamily: Poly A polymerase C-terminal region-like Family: Poly A polymerase C-terminal region-like Phyre2 PDB 2la3 chain A Region: 45 - 193 Aligned: 123 Modelled: 134 Confidence: 96.7% Identity: 21% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the nmr structure of the protein np_344798.1 reveals a cca-adding2 enzyme head domain Phyre2 PDB 2fcl chain A domain 1 Region: 43 - 119 Aligned: 77 Modelled: 77 Confidence: 91.6% Identity: 22% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: TM1012-like Phyre2 PDB 2qgs chain A domain 1 Region: 284 - 377 Aligned: 80 Modelled: 93 Confidence: 86.8% Identity: 10% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 2pq7 chain A domain 1 Region: 264 - 378 Aligned: 105 Modelled: 114 Confidence: 80.8% Identity: 7% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 1r89 chain A domain 2 Region: 41 - 120 Aligned: 79 Modelled: 80 Confidence: 69.0% Identity: 20% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Archaeal tRNA CCA-adding enzyme catalytic domain Phyre2 PDB 3djb chain A domain 1 Region: 285 - 374 Aligned: 74 Modelled: 90 Confidence: 63.8% Identity: 14% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 1y81 chain A domain 1 Region: 38 - 105 Aligned: 66 Modelled: 68 Confidence: 58.2% Identity: 23% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 2d59 chain A domain 1 Region: 45 - 105 Aligned: 60 Modelled: 61 Confidence: 46.9% Identity: 23% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 1jms chain A domain 4 Region: 32 - 88 Aligned: 48 Modelled: 57 Confidence: 43.2% Identity: 19% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: DNA polymerase beta-like Phyre2 1 c3aqnA_ 2 c1miyB_ 3 c1vfgB_ 4 c3h37B_ 5 c1ou5A_ 6 d1miwa2 7 d1ou5a2 8 d1vfga2 9 d1miwa1 10 d1vfga1 11 d1ou5a1 12 c2la3A_ 13 d2fcla1 14 d2qgsa1 15 d2pq7a1 16 d1r89a2 17 d3djba1 18 d1y81a1 19 d2d59a1 20 d1jmsa4 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3aqnA_ 100.0 100 PDB header:transferase Chain: A: PDB Molecule:poly(a) polymerase; PDBTitle: complex structure of bacterial protein (apo form ii) 2 c1miyB_ 100.0 28 PDB header:translation, transferase Chain: B: PDB Molecule:trna cca-adding enzyme; PDBTitle: crystal structure of bacillus stearothermophilus cca-adding enzyme in2 complex with ctp 3 c1vfgB_ 100.0 24 PDB header:transferase/rna Chain: B: PDB Molecule:poly a polymerase; PDBTitle: crystal structure of trna nucleotidyltransferase complexed2 with a primer trna and an incoming atp analog 4 c3h37B_ 100.0 21 PDB header:transferase Chain: B: PDB Molecule:trna nucleotidyl transferase-related protein; PDBTitle: the structure of cca-adding enzyme apo form i 5 c1ou5A_ 100.0 26 PDB header:translation, transferase Chain: A: PDB Molecule:trna cca-adding enzyme; PDBTitle: crystal structure of human cca-adding enzyme 6 d1miwa2 100.0 38 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Poly A polymerase head domain-like 7 d1ou5a2 100.0 35 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Poly A polymerase head domain-like 8 d1vfga2 100.0 40 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Poly A polymerase head domain-like 9 d1miwa1 100.0 21 Fold:Poly A polymerase C-terminal region-like Superfamily:Poly A polymerase C-terminal region-like Family:Poly A polymerase C-terminal region-like 10 d1vfga1 100.0 18 Fold:Poly A polymerase C-terminal region-like Superfamily:Poly A polymerase C-terminal region-like Family:Poly A polymerase C-terminal region-like 11 d1ou5a1 100.0 19 Fold:Poly A polymerase C-terminal region-like Superfamily:Poly A polymerase C-terminal region-like Family:Poly A polymerase C-terminal region-like 12 c2la3A_ 96.7 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the nmr structure of the protein np_344798.1 reveals a cca-adding2 enzyme head domain 13 d2fcla1 91.6 22 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:TM1012-like 14 d2qgsa1 86.8 10 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 15 d2pq7a1 80.8 7 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 16 d1r89a2 69.0 20 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Archaeal tRNA CCA-adding enzyme catalytic domain 17 d3djba1 63.8 14 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 18 d1y81a1 58.2 23 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 19 d2d59a1 46.9 23 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 20 d1jmsa4 43.2 19 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:DNA polymerase beta-like 21 d1iowa1 not modelled 39.9 20 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:D-Alanine ligase N-terminal domain 22 c2q14A_ not modelled 38.4 7 PDB header:hydrolase Chain: A: PDB Molecule:phosphohydrolase; PDBTitle: crystal structure of phosphohydrolase (bt4208) from bacteroides2 thetaiotaomicron vpi-5482 at 2.20 a resolution 23 c3mdoB_ not modelled 34.9 32 PDB header:ligase Chain: B: PDB Molecule:putative phosphoribosylformylglycinamidine cyclo-ligase; PDBTitle: crystal structure of a putative phosphoribosylformylglycinamidine2 cyclo-ligase (bdi_2101) from parabacteroides distasonis atcc 8503 at3 1.91 a resolution 24 d1b7go1 not modelled 34.9 27 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 25 d2fmpa3 not modelled 33.0 26 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:DNA polymerase beta-like 26 c3skdA_ not modelled 31.0 11 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein tthb187; PDBTitle: crystal structure of the thermus thermophilus cas3 hd domain in the2 presence of ni2+ 27 c3fpnA_ not modelled 30.3 18 PDB header:dna binding protein Chain: A: PDB Molecule:geobacillus stearothermophilus uvra interaction PDBTitle: crystal structure of uvra-uvrb interaction domains 28 d1n57a_ not modelled 29.2 17 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:DJ-1/PfpI 29 c2duwA_ not modelled 28.9 21 PDB header:ligand binding protein Chain: A: PDB Molecule:putative coa-binding protein; PDBTitle: solution structure of putative coa-binding protein of2 klebsiella pneumoniae 30 c1x60A_ not modelled 28.5 30 PDB header:hydrolase Chain: A: PDB Molecule:sporulation-specific n-acetylmuramoyl-l-alanine PDBTitle: solution structure of the peptidoglycan binding domain of2 b. subtilis cell wall lytic enzyme cwlc 31 c2pcnA_ not modelled 28.5 18 PDB header:transferase Chain: A: PDB Molecule:s-adenosylmethionine:2-demethylmenaquinone PDBTitle: crystal structure of s-adenosylmethionine: 2-dimethylmenaquinone2 methyltransferase (gk_1813) from geobacillus kaustophilus hta426 32 c2ze5A_ not modelled 28.0 13 PDB header:transferase Chain: A: PDB Molecule:isopentenyl transferase; PDBTitle: crystal structure of adenosine phosphate-isopentenyltransferase 33 d2bcqa3 not modelled 27.6 23 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:DNA polymerase beta-like 34 c3k4iC_ not modelled 27.0 18 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein pspto_3204 from2 pseudomonas syringae pv. tomato str. dc3000 35 d2bdua1 not modelled 26.9 21 Fold:HAD-like Superfamily:HAD-like Family:Pyrimidine 5'-nucleotidase (UMPH-1) 36 c3c8oB_ not modelled 24.9 32 PDB header:hydrolase regulator Chain: B: PDB Molecule:regulator of ribonuclease activity a; PDBTitle: the crystal structure of rraa from pao1 37 d1vi4a_ not modelled 24.9 27 Fold:The "swivelling" beta/beta/alpha domain Superfamily:RraA-like Family:RraA-like 38 d1no5a_ not modelled 24.0 25 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Catalytic subunit of bi-partite nucleotidyltransferase 39 d1clia2 not modelled 23.9 32 Fold:PurM C-terminal domain-like Superfamily:PurM C-terminal domain-like Family:PurM C-terminal domain-like 40 d1j3la_ not modelled 23.8 32 Fold:The "swivelling" beta/beta/alpha domain Superfamily:RraA-like Family:RraA-like 41 d2vana2 not modelled 23.5 26 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:DNA polymerase beta-like 42 d1q5xa_ not modelled 23.3 18 Fold:The "swivelling" beta/beta/alpha domain Superfamily:RraA-like Family:RraA-like 43 d1iuka_ not modelled 23.3 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 44 c3m5fA_ not modelled 23.2 10 PDB header:hydrolase Chain: A: PDB Molecule:metal dependent phosphohydrolase; PDBTitle: structure of mj0384, a cas3 protein from methanocaldococcus jannaschii 45 c1nxjA_ not modelled 23.1 27 PDB header:unknown function Chain: A: PDB Molecule:probable s-adenosylmethionine:2- PDBTitle: structure of rv3853 from mycobacterium tuberculosis 46 d1nxja_ not modelled 23.1 27 Fold:The "swivelling" beta/beta/alpha domain Superfamily:RraA-like Family:RraA-like 47 c2c5qE_ not modelled 22.7 23 PDB header:structural genomics,unknown function Chain: E: PDB Molecule:rraa-like protein yer010c; PDBTitle: crystal structure of yeast yer010cp 48 c3a8tA_ not modelled 22.6 15 PDB header:transferase Chain: A: PDB Molecule:adenylate isopentenyltransferase; PDBTitle: plant adenylate isopentenyltransferase in complex with atp 49 d1wota_ not modelled 22.5 12 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Catalytic subunit of bi-partite nucleotidyltransferase 50 d2vkqa1 not modelled 22.2 19 Fold:HAD-like Superfamily:HAD-like Family:Pyrimidine 5'-nucleotidase (UMPH-1) 51 d1yt8a4 not modelled 21.9 20 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 52 c3d54I_ not modelled 21.3 22 PDB header:ligase Chain: I: PDB Molecule:phosphoribosylformylglycinamidine synthase ii; PDBTitle: stucture of purlqs from thermotoga maritima 53 c3g5jA_ not modelled 21.1 22 PDB header:nucleotide binding protein Chain: A: PDB Molecule:putative atp/gtp binding protein; PDBTitle: crystal structure of n-terminal domain of putative atp/gtp binding2 protein from clostridium difficile 630 54 c2w9mB_ not modelled 21.0 19 PDB header:dna replication Chain: B: PDB Molecule:polymerase x; PDBTitle: structure of family x dna polymerase from deinococcus2 radiodurans 55 d2fuea1 not modelled 20.0 14 Fold:HAD-like Superfamily:HAD-like Family:Predicted hydrolases Cof 56 c3exaD_ not modelled 19.9 18 PDB header:transferase Chain: D: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of the full-length trna2 isopentenylpyrophosphate transferase (bh2366) from3 bacillus halodurans, northeast structural genomics4 consortium target bhr41. 57 d1wpga2 not modelled 19.4 13 Fold:HAD-like Superfamily:HAD-like Family:Meta-cation ATPase, catalytic domain P 58 d1vk3a1 not modelled 18.7 53 Fold:Bacillus chorismate mutase-like Superfamily:PurM N-terminal domain-like Family:PurM N-terminal domain-like 59 c3d3qB_ not modelled 18.1 15 PDB header:transferase Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of trna delta(2)-isopentenylpyrophosphate2 transferase (se0981) from staphylococcus epidermidis.3 northeast structural genomics consortium target ser100 60 c3ib6B_ not modelled 17.6 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein from listeria2 monocytogenes serotype 4b 61 d2heka1 not modelled 17.4 17 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 62 c2zodB_ not modelled 16.7 18 PDB header:transferase Chain: B: PDB Molecule:selenide, water dikinase; PDBTitle: crystal structure of selenophosphate synthetase from2 aquifex aeolicus 63 c2cx9C_ not modelled 16.6 16 PDB header:oxidoreductase Chain: C: PDB Molecule:acyl-coa dehydrogenase; PDBTitle: crystal structure of acyl-coa dehydrogenase 64 c3kizA_ not modelled 16.2 24 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylformylglycinamidine cyclo-ligase; PDBTitle: crystal structure of putative phosphoribosylformylglycinamidine cyclo-2 ligase (yp_676759.1) from cytophaga hutchinsonii atcc 33406 at 1.50 a3 resolution 65 c3crqA_ not modelled 16.0 22 PDB header:transferase Chain: A: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: structure of trna dimethylallyltransferase: rna2 modification through a channel 66 c2yxbA_ not modelled 16.0 25 PDB header:isomerase Chain: A: PDB Molecule:coenzyme b12-dependent mutase; PDBTitle: crystal structure of the methylmalonyl-coa mutase alpha-subunit from2 aeropyrum pernix 67 c1wv9B_ not modelled 15.8 32 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:rhodanese homolog tt1651; PDBTitle: crystal structure of rhodanese homolog tt1651 from an2 extremely thermophilic bacterium thermus thermophilus hb8 68 c1sz1A_ not modelled 15.6 20 PDB header:transferase/rna Chain: A: PDB Molecule:trna nucleotidyltransferase; PDBTitle: mechanism of cca-adding enzymes specificity revealed by crystal2 structures of ternary complexes 69 c3nojA_ not modelled 15.6 36 PDB header:lyase Chain: A: PDB Molecule:4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate PDBTitle: the structure of hmg/cha aldolase from the protocatechuate degradation2 pathway of pseudomonas putida 70 c2pfrB_ not modelled 15.5 22 PDB header:transferase Chain: B: PDB Molecule:arylamine n-acetyltransferase 2; PDBTitle: human n-acetyltransferase 2 71 d2b8ea1 not modelled 15.5 21 Fold:HAD-like Superfamily:HAD-like Family:Meta-cation ATPase, catalytic domain P 72 c3d9wA_ not modelled 15.0 25 PDB header:transferase Chain: A: PDB Molecule:putative acetyltransferase; PDBTitle: crystal structure analysis of nocardia farcinica arylamine2 n-acetyltransferase 73 d1p49a_ not modelled 14.6 13 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 74 d1w4ta1 not modelled 13.7 40 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Arylamine N-acetyltransferase 75 c2crlA_ not modelled 12.7 32 PDB header:chaperone Chain: A: PDB Molecule:copper chaperone for superoxide dismutase; PDBTitle: the apo form of hma domain of copper chaperone for2 superoxide dismutase 76 c3ff4A_ not modelled 12.3 32 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein chu_1412 77 c3lnbA_ not modelled 12.1 33 PDB header:transferase Chain: A: PDB Molecule:n-acetyltransferase family protein; PDBTitle: crystal structure analysis of arylamine n-acetyltransferase c from2 bacillus anthracis 78 d1r9la_ not modelled 12.0 19 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 79 d1zpda1 not modelled 11.9 16 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 80 c3ix9B_ not modelled 11.9 19 PDB header:oxidoreductase Chain: B: PDB Molecule:dihydrofolate reductase; PDBTitle: crystal structure of streptococcus pneumoniae dihydrofolate2 reductase - sp9 mutant 81 c1cliD_ not modelled 11.8 32 PDB header:ligase Chain: D: PDB Molecule:protein (phosphoribosyl-aminoimidazole synthetase); PDBTitle: x-ray crystal structure of aminoimidazole ribonucleotide synthetase2 (purm), from the e. coli purine biosynthetic pathway, at 2.5 a3 resolution 82 d1jcea2 not modelled 11.5 29 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 83 d1fe0a_ not modelled 11.5 21 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 84 d1xpja_ not modelled 11.4 8 Fold:HAD-like Superfamily:HAD-like Family:Hypothetical protein VC0232 85 d1xbta1 not modelled 11.4 10 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Type II thymidine kinase 86 c2pr7A_ not modelled 11.3 11 PDB header:hydrolase Chain: A: PDB Molecule:haloacid dehalogenase/epoxide hydrolase family; PDBTitle: crystal structure of uncharacterized protein (np_599989.1) from2 corynebacterium glutamicum atcc 13032 kitasato at 1.44 a resolution 87 d2b7oa1 not modelled 11.2 46 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class-II DAHP synthetase 88 c3u1nC_ not modelled 11.0 10 PDB header:hydrolase Chain: C: PDB Molecule:sam domain and hd domain-containing protein 1; PDBTitle: structure of the catalytic core of human samhd1 89 c2jtqA_ not modelled 11.0 22 PDB header:transferase Chain: A: PDB Molecule:phage shock protein e; PDBTitle: rhodanese from e.coli 90 c3fozB_ not modelled 11.0 27 PDB header:transferase/rna Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate transferase; PDBTitle: structure of e. coli isopentenyl-trna transferase in complex with e.2 coli trna(phe) 91 c3fryB_ not modelled 11.0 35 PDB header:hydrolase Chain: B: PDB Molecule:probable copper-exporting p-type atpase a; PDBTitle: crystal structure of the copa c-terminal metal binding domain 92 c2i7dB_ not modelled 10.9 15 PDB header:hydrolase Chain: B: PDB Molecule:5'(3')-deoxyribonucleotidase, cytosolic type; PDBTitle: structure of human cytosolic deoxyribonucleotidase in2 complex with deoxyuridine, alf4 and mg2+ 93 d1z5ga1 not modelled 10.8 21 Fold:HAD-like Superfamily:HAD-like Family:Class B acid phosphatase, AphA 94 c2kmvA_ not modelled 10.7 21 PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 1; PDBTitle: solution structure of the nucleotide binding domain of the2 human menkes protein in the atp-free form 95 c2v9yA_ not modelled 10.7 23 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylformylglycinamidine cyclo-ligase; PDBTitle: human aminoimidazole ribonucleotide synthetase 96 c2z01A_ not modelled 10.7 27 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylformylglycinamidine cyclo-ligase; PDBTitle: crystal structure of phosphoribosylaminoimidazole2 synthetase from geobacillus kaustophilus 97 d1nlna_ not modelled 10.5 13 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Adenain-like 98 d2bsza1 not modelled 10.4 27 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Arylamine N-acetyltransferase 99 d1u6za1 not modelled 10.3 10 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:Ppx associated domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0