Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	N	N	I	L	V	V	C	V	G	N	I	C	R	S	P	T	A	E	R	L	L	Q	R	Y	H	P	E	L	K	V	E	S	A	G	L	G	A	L	V	G	K	G	A	D	P	T	A	I	S	V	A	A	E	H	Q	L	S	L
Secondary structure
SS confidence
Disorder		?	?	?																																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	G	H	C	A	R	Q	I	S	R	R	L	C	R	N	Y	D	L	I	L	T	M	E	K	R	H	I	E	R	L	C	E	M	A	P	E	M	R	G	K	V	M	L	F	G	H	W	D	N	E	C	E	I	P	D	P	Y	R	K	S
Secondary structure
SS confidence
Disorder						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.
Sequence		R	E	T	F	A	A	V	Y	T	L	L	E	R	S	A	R	Q	W	A	Q	A	L	N	A	E	Q	V
Secondary structure
SS confidence
Disorder																									?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2fek chain A Region: 1 - 147 Aligned: 147 Modelled: 147 Confidence: 100.0% Identity: 100% PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine- PDBTitle: structure of a protein tyrosine phosphatase Phyre2 PDB 2wmy chain H Region: 1 - 142 Aligned: 142 Modelled: 142 Confidence: 100.0% Identity: 54% PDB header:hydrolase Chain: H: PDB Molecule:putative acid phosphatase wzb; PDBTitle: crystal structure of the tyrosine phosphatase wzb from2 escherichia coli k30 in complex with sulphate. Phyre2 PDB 1dg9 chain A Region: 1 - 143 Aligned: 142 Modelled: 143 Confidence: 100.0% Identity: 30% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 2gi4 chain A Region: 2 - 145 Aligned: 142 Modelled: 144 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:possible phosphotyrosine protein phosphatase; PDBTitle: solution structure of the low molecular weight protein2 tyrosine phosphatase from campylobacter jejuni. Phyre2 PDB 3jvi chain A Region: 4 - 147 Aligned: 141 Modelled: 144 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:protein tyrosine phosphatase; PDBTitle: product state mimic crystal structure of protein tyrosine phosphatase2 from entamoeba histolytica Phyre2 PDB 2cwd chain A Region: 3 - 142 Aligned: 139 Modelled: 140 Confidence: 100.0% Identity: 37% PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight phosphotyrosine protein phosphatase; PDBTitle: crystal structure of tt1001 protein from thermus thermophilus hb8 Phyre2 PDB 3rof chain A Region: 2 - 145 Aligned: 140 Modelled: 142 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine-phosphatase ptpa; PDBTitle: crystal structure of the s. aureus protein tyrosine phosphatase ptpa Phyre2 PDB 5pnt chain A Region: 2 - 142 Aligned: 140 Modelled: 141 Confidence: 100.0% Identity: 30% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 1p8a chain A Region: 1 - 143 Aligned: 140 Modelled: 140 Confidence: 100.0% Identity: 22% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 1zgg chain A Region: 4 - 146 Aligned: 142 Modelled: 143 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: A: PDB Molecule:putative low molecular weight protein-tyrosine- PDBTitle: solution structure of a low molecular weight protein2 tyrosine phosphatase from bacillus subtilis Phyre2 PDB 1u2p chain A Region: 3 - 145 Aligned: 140 Modelled: 143 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine- PDBTitle: crystal structure of mycobacterium tuberculosis low2 molecular protein tyrosine phosphatase (mptpa) at 1.9a3 resolution Phyre2 PDB 1d1q chain A Region: 2 - 141 Aligned: 139 Modelled: 140 Confidence: 100.0% Identity: 28% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 2l18 chain A Region: 2 - 143 Aligned: 130 Modelled: 139 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: an arsenate reductase in the phosphate binding state Phyre2 PDB 1jf8 chain A Region: 2 - 139 Aligned: 126 Modelled: 138 Confidence: 100.0% Identity: 23% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 1jl3 chain A Region: 3 - 143 Aligned: 135 Modelled: 138 Confidence: 100.0% Identity: 22% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 1y1l chain A Region: 4 - 140 Aligned: 123 Modelled: 129 Confidence: 100.0% Identity: 27% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 3rh0 chain A Region: 2 - 139 Aligned: 125 Modelled: 138 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: corynebacterium glutamicum mycothiol/mycoredoxin1-dependent arsenate2 reductase cg_arsc2 Phyre2 PDB 3t38 chain B Region: 4 - 146 Aligned: 117 Modelled: 131 Confidence: 100.0% Identity: 23% PDB header:oxidoreductase Chain: B: PDB Molecule:arsenate reductase; PDBTitle: corynebacterium glutamicum thioredoxin-dependent arsenate reductase2 cg_arsc1' Phyre2 PDB 3fdf chain A Region: 4 - 145 Aligned: 135 Modelled: 141 Confidence: 97.5% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:fr253; PDBTitle: crystal structure of the serine phosphatase of rna2 polymerase ii ctd (ssu72 superfamily) from drosophila3 melanogaster. orthorhombic crystal form. northeast4 structural genomics consortium target fr253. Phyre2 PDB 3o2q chain B Region: 4 - 94 Aligned: 85 Modelled: 91 Confidence: 96.9% Identity: 31% PDB header:hydrolase Chain: B: PDB Molecule:rna polymerase ii subunit a c-terminal domain phosphatase PDBTitle: crystal structure of the human symplekin-ssu72-ctd phosphopeptide2 complex Phyre2 1 c2fekA_ 2 c2wmyH_ 3 d1dg9a_ 4 c2gi4A_ 5 c3jviA_ 6 c2cwdA_ 7 c3rofA_ 8 d5pnta_ 9 d1p8aa_ 10 c1zggA_ 11 c1u2pA_ 12 d1d1qa_ 13 c2l18A_ 14 d1jf8a_ 15 d1jl3a_ 16 d1y1la_ 17 c3rh0A_ 18 c3t38B_ 19 c3fdfA_ 20 c3o2qB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2fekA_ 100.0 100 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine- PDBTitle: structure of a protein tyrosine phosphatase 2 c2wmyH_ 100.0 54 PDB header:hydrolase Chain: H: PDB Molecule:putative acid phosphatase wzb; PDBTitle: crystal structure of the tyrosine phosphatase wzb from2 escherichia coli k30 in complex with sulphate. 3 d1dg9a_ 100.0 30 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 4 c2gi4A_ 100.0 24 PDB header:hydrolase Chain: A: PDB Molecule:possible phosphotyrosine protein phosphatase; PDBTitle: solution structure of the low molecular weight protein2 tyrosine phosphatase from campylobacter jejuni. 5 c3jviA_ 100.0 27 PDB header:hydrolase Chain: A: PDB Molecule:protein tyrosine phosphatase; PDBTitle: product state mimic crystal structure of protein tyrosine phosphatase2 from entamoeba histolytica 6 c2cwdA_ 100.0 37 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight phosphotyrosine protein phosphatase; PDBTitle: crystal structure of tt1001 protein from thermus thermophilus hb8 7 c3rofA_ 100.0 24 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine-phosphatase ptpa; PDBTitle: crystal structure of the s. aureus protein tyrosine phosphatase ptpa 8 d5pnta_ 100.0 30 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 9 d1p8aa_ 100.0 22 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 10 c1zggA_ 100.0 29 PDB header:hydrolase Chain: A: PDB Molecule:putative low molecular weight protein-tyrosine- PDBTitle: solution structure of a low molecular weight protein2 tyrosine phosphatase from bacillus subtilis 11 c1u2pA_ 100.0 28 PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine- PDBTitle: crystal structure of mycobacterium tuberculosis low2 molecular protein tyrosine phosphatase (mptpa) at 1.9a3 resolution 12 d1d1qa_ 100.0 28 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 13 c2l18A_ 100.0 22 PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: an arsenate reductase in the phosphate binding state 14 d1jf8a_ 100.0 23 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 15 d1jl3a_ 100.0 22 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 16 d1y1la_ 100.0 27 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 17 c3rh0A_ 100.0 21 PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: corynebacterium glutamicum mycothiol/mycoredoxin1-dependent arsenate2 reductase cg_arsc2 18 c3t38B_ 100.0 23 PDB header:oxidoreductase Chain: B: PDB Molecule:arsenate reductase; PDBTitle: corynebacterium glutamicum thioredoxin-dependent arsenate reductase2 cg_arsc1' 19 c3fdfA_ 97.5 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:fr253; PDBTitle: crystal structure of the serine phosphatase of rna2 polymerase ii ctd (ssu72 superfamily) from drosophila3 melanogaster. orthorhombic crystal form. northeast4 structural genomics consortium target fr253. 20 c3o2qB_ 96.9 31 PDB header:hydrolase Chain: B: PDB Molecule:rna polymerase ii subunit a c-terminal domain phosphatase PDBTitle: crystal structure of the human symplekin-ssu72-ctd phosphopeptide2 complex 21 c3o2sB_ not modelled 96.6 32 PDB header:hydrolase Chain: B: PDB Molecule:rna polymerase ii subunit a c-terminal domain phosphatase PDBTitle: crystal structure of the human symplekin-ssu72 complex 22 c2f00A_ not modelled 93.3 17 PDB header:ligase Chain: A: PDB Molecule:udp-n-acetylmuramate--l-alanine ligase; PDBTitle: escherichia coli murc 23 d1gpja2 not modelled 91.8 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 24 c1j6uA_ not modelled 89.0 15 PDB header:ligase Chain: A: PDB Molecule:udp-n-acetylmuramate-alanine ligase murc; PDBTitle: crystal structure of udp-n-acetylmuramate-alanine ligase2 murc (tm0231) from thermotoga maritima at 2.3 a resolution 25 d1p3da1 not modelled 87.8 20 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 26 c1gpjA_ not modelled 86.7 16 PDB header:reductase Chain: A: PDB Molecule:glutamyl-trna reductase; PDBTitle: glutamyl-trna reductase from methanopyrus kandleri 27 d1j6ua1 not modelled 83.9 14 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 28 c1gqqA_ not modelled 82.6 20 PDB header:cell wall biosynthesis Chain: A: PDB Molecule:udp-n-acetylmuramate-l-alanine ligase; PDBTitle: murc - crystal structure of the apo-enzyme from haemophilus2 influenzae 29 c2bibA_ not modelled 81.6 9 PDB header:hydrolase Chain: A: PDB Molecule:teichoic acid phosphorylcholine esterase/ choline binding PDBTitle: crystal structure of the complete modular teichioic acid2 phosphorylcholine esterase pce (cbpe) from streptococcus3 pneumoniae 30 c3eagA_ not modelled 76.0 12 PDB header:ligase Chain: A: PDB Molecule:udp-n-acetylmuramate:l-alanyl-gamma-d-glutamyl-meso- PDBTitle: the crystal structure of udp-n-acetylmuramate:l-alanyl-gamma-d-2 glutamyl-meso-diaminopimelate ligase (mpl) from neisseria3 meningitides 31 c2eq8C_ not modelled 72.3 21 PDB header:oxidoreductase Chain: C: PDB Molecule:pyruvate dehydrogenase complex, dihydrolipoamide PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdp 32 c3czcA_ not modelled 71.9 14 PDB header:transferase Chain: A: PDB Molecule:rmpb; PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans 33 d1vlva2 not modelled 71.3 8 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 34 d1u6ka1 not modelled 71.3 25 Fold:F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) Superfamily:F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) Family:F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) 35 d1vkra_ not modelled 71.2 21 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Lactose/Cellobiose specific IIB subunit 36 c1vkrA_ not modelled 71.2 21 PDB header:transferase Chain: A: PDB Molecule:mannitol-specific pts system enzyme iiabc components; PDBTitle: structure of iib domain of the mannitol-specific permease enzyme ii 37 c3ktdC_ not modelled 71.0 13 PDB header:oxidoreductase Chain: C: PDB Molecule:prephenate dehydrogenase; PDBTitle: crystal structure of a putative prephenate dehydrogenase (cgl0226)2 from corynebacterium glutamicum atcc 13032 at 2.60 a resolution 38 d1pjqa1 not modelled 70.1 22 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Siroheme synthase N-terminal domain-like 39 c3kcqA_ not modelled 69.5 15 PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase; PDBTitle: crystal structure of phosphoribosylglycinamide formyltransferase from2 anaplasma phagocytophilum 40 c3oj0A_ not modelled 64.5 22 PDB header:oxidoreductase Chain: A: PDB Molecule:glutamyl-trna reductase; PDBTitle: crystal structure of glutamyl-trna reductase from thermoplasma2 volcanium (nucleotide binding domain) 41 c3hn7A_ not modelled 63.8 13 PDB header:ligase Chain: A: PDB Molecule:udp-n-acetylmuramate-l-alanine ligase; PDBTitle: crystal structure of a murein peptide ligase mpl (psyc_0032) from2 psychrobacter arcticus 273-4 at 1.65 a resolution 42 c2ph5A_ not modelled 60.3 9 PDB header:transferase Chain: A: PDB Molecule:homospermidine synthase; PDBTitle: crystal structure of the homospermidine synthase hss from legionella2 pneumophila in complex with nad, northeast structural genomics target3 lgr54 43 c1e0cA_ not modelled 57.3 16 PDB header:sulfurtransferase Chain: A: PDB Molecule:sulfurtransferase; PDBTitle: sulfurtransferase from azotobacter vinelandii 44 c1wv9B_ not modelled 56.3 28 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:rhodanese homolog tt1651; PDBTitle: crystal structure of rhodanese homolog tt1651 from an2 extremely thermophilic bacterium thermus thermophilus hb8 45 d2czca2 not modelled 56.2 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 46 c3d1pA_ not modelled 55.9 14 PDB header:transferase Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase yor285w; PDBTitle: atomic resolution structure of uncharacterized protein from2 saccharomyces cerevisiae 47 c2k0zA_ not modelled 55.7 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein hp1203; PDBTitle: solution nmr structure of protein hp1203 from helicobacter pylori2 26695. northeast structural genomics consortium (nesg) target3 pt1/ontario center for structural proteomics target hp1203 48 d1w4ha1 not modelled 55.0 16 Fold:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Superfamily:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Family:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 49 d1yt8a4 not modelled 54.8 12 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 50 d1bala_ not modelled 54.8 19 Fold:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Superfamily:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Family:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 51 d2z06a1 not modelled 54.6 18 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TTHA0625-like 52 d2fug21 not modelled 54.5 29 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:NQO2-like 53 c3fojA_ not modelled 53.9 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of ssp1007 from staphylococcus2 saprophyticus subsp. saprophyticus. northeast structural3 genomics target syr101a. 54 d1w85i_ not modelled 53.7 13 Fold:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Superfamily:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Family:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 55 c2i99A_ not modelled 53.3 15 PDB header:oxidoreductase Chain: A: PDB Molecule:mu-crystallin homolog; PDBTitle: crystal structure of human mu_crystallin at 2.6 angstrom 56 c1tvmA_ not modelled 53.3 24 PDB header:transferase Chain: A: PDB Molecule:pts system, galactitol-specific iib component; PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system 57 c3c1oA_ not modelled 52.4 8 PDB header:oxidoreductase Chain: A: PDB Molecule:eugenol synthase; PDBTitle: the multiple phenylpropene synthases in both clarkia2 breweri and petunia hybrida represent two distinct lineages 58 c2eq9C_ not modelled 51.7 25 PDB header:oxidoreductase Chain: C: PDB Molecule:pyruvate dehydrogenase complex, dihydrolipoamide PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdb 59 d1wraa1 not modelled 49.7 9 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Pce catalytic domain-like 60 c3dfzB_ not modelled 49.6 16 PDB header:oxidoreductase Chain: B: PDB Molecule:precorrin-2 dehydrogenase; PDBTitle: sirc, precorrin-2 dehydrogenase 61 d1cmca_ not modelled 49.5 15 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Met repressor, MetJ (MetR) 62 c2auvA_ not modelled 49.0 21 PDB header:oxidoreductase Chain: A: PDB Molecule:potential nad-reducing hydrogenase subunit; PDBTitle: solution structure of hndac : a thioredoxin-like [2fe-2s]2 ferredoxin involved in the nadp-reducing hydrogenase3 complex 63 c2eq7C_ not modelled 48.2 19 PDB header:oxidoreductase Chain: C: PDB Molecule:2-oxoglutarate dehydrogenase e2 component; PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdo 64 d2cyua1 not modelled 48.2 19 Fold:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Superfamily:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex Family:Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 65 c3tqrA_ not modelled 48.0 15 PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase; PDBTitle: structure of the phosphoribosylglycinamide formyltransferase (purn) in2 complex with ches from coxiella burnetii 66 c3emeA_ not modelled 46.9 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:rhodanese-like domain protein; PDBTitle: crystal structure of rhodanese-like domain protein from2 staphylococcus aureus 67 c1zwvA_ not modelled 46.3 22 PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase component of branched- PDBTitle: solution structure of the subunit binding domain (hbsbd) of2 the human mitochondrial branched-chain alpha-ketoacid3 dehydrogenase 68 c1w3dA_ not modelled 46.2 13 PDB header:transferase Chain: A: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase PDBTitle: nmr structure of the peripheral-subunit binding domain of2 bacillus stearothermophilus e2p 69 c2jrlA_ not modelled 45.3 19 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: solution structure of the beryllofluoride-activated ntrc4 receiver2 domain dimer 70 c3i2vA_ not modelled 44.9 29 PDB header:transferase Chain: A: PDB Molecule:adenylyltransferase and sulfurtransferase mocs3; PDBTitle: crystal structure of human mocs3 rhodanese-like domain 71 d1t71a_ not modelled 43.6 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:DR1281-like 72 c1w4kA_ not modelled 43.2 19 PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase e2; PDBTitle: peripheral-subunit binding domains from mesophilic,2 thermophilic, and hyperthermophilic bacteria fold by3 ultrafast, apparently two-state transitions 73 c3ilmD_ not modelled 42.5 24 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:alr3790 protein; PDBTitle: crystal structure of the alr3790 protein from anabaena sp. northeast2 structural genomics consortium target nsr437h 74 c2e85B_ not modelled 42.5 23 PDB header:hydrolase Chain: B: PDB Molecule:hydrogenase 3 maturation protease; PDBTitle: crystal structure of the hydrogenase 3 maturation protease 75 d1f0ya2 not modelled 42.1 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 76 c2cooA_ not modelled 41.6 25 PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase component of branched- PDBTitle: solution structure of the e3_binding domain of2 dihydrolipoamide branched chaintransacylase 77 d1rrma_ not modelled 41.0 7 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 78 d1w85b2 not modelled 41.0 11 Fold:TK C-terminal domain-like Superfamily:TK C-terminal domain-like Family:Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain 79 d1f37b_ not modelled 40.8 22 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioredoxin-like 2Fe-2S ferredoxin 80 c2rgwD_ not modelled 40.5 10 PDB header:transferase Chain: D: PDB Molecule:aspartate carbamoyltransferase; PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase 81 c3k96B_ not modelled 38.7 9 PDB header:oxidoreductase Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+]; PDBTitle: 2.1 angstrom resolution crystal structure of glycerol-3-phosphate2 dehydrogenase (gpsa) from coxiella burnetii 82 c3g5jA_ not modelled 38.6 24 PDB header:nucleotide binding protein Chain: A: PDB Molecule:putative atp/gtp binding protein; PDBTitle: crystal structure of n-terminal domain of putative atp/gtp binding2 protein from clostridium difficile 630 83 c2weuD_ not modelled 36.9 20 PDB header:antifungal protein Chain: D: PDB Molecule:tryptophan 5-halogenase; PDBTitle: crystal structure of tryptophan 5-halogenase (pyrh) complex2 with substrate tryptophan 84 c3dv0I_ not modelled 36.6 18 PDB header:oxidoreductase/transferase Chain: I: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase PDBTitle: snapshots of catalysis in the e1 subunit of the pyruvate2 dehydrogenase multi-enzyme complex 85 d1jzta_ not modelled 36.4 9 Fold:YjeF N-terminal domain-like Superfamily:YjeF N-terminal domain-like Family:YjeF N-terminal domain-like 86 d1okga2 not modelled 35.4 9 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 87 c3gt0A_ not modelled 35.2 9 PDB header:oxidoreductase Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase; PDBTitle: crystal structure of pyrroline 5-carboxylate reductase from bacillus2 cereus. northeast structural genomics consortium target bcr38b 88 c3luyA_ not modelled 34.6 11 PDB header:isomerase Chain: A: PDB Molecule:probable chorismate mutase; PDBTitle: putative chorismate mutase from bifidobacterium adolescentis 89 c3dcjA_ not modelled 34.5 18 PDB header:transferase Chain: A: PDB Molecule:probable 5'-phosphoribosylglycinamide PDBTitle: crystal structure of glycinamide formyltransferase (purn)2 from mycobacterium tuberculosis in complex with 5-methyl-5,3 6,7,8-tetrahydrofolic acid derivative 90 d1cfza_ not modelled 32.7 37 Fold:Phosphorylase/hydrolase-like Superfamily:HybD-like Family:Hydrogenase maturating endopeptidase HybD 91 d1urha1 not modelled 32.6 21 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 92 c3l6dB_ not modelled 32.3 11 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase from pseudomonas putida2 kt2440 93 d1e0ca1 not modelled 32.2 16 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 94 c2hi1A_ not modelled 32.2 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 2; PDBTitle: the structure of a putative 4-hydroxythreonine-4-phosphate2 dehydrogenase from salmonella typhimurium. 95 c3bfjK_ not modelled 31.5 12 PDB header:oxidoreductase Chain: K: PDB Molecule:1,3-propanediol oxidoreductase; PDBTitle: crystal structure analysis of 1,3-propanediol oxidoreductase 96 c3nbmA_ not modelled 31.5 20 PDB header:transferase Chain: A: PDB Molecule:pts system, lactose-specific iibc components; PDBTitle: the lactose-specific iib component domain structure of the2 phosphoenolpyruvate:carbohydrate phosphotransferase system (pts) from3 streptococcus pneumoniae. 97 d1iiba_ not modelled 30.7 11 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Lactose/Cellobiose specific IIB subunit 98 c3ippA_ not modelled 29.7 11 PDB header:transferase Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase ynje; PDBTitle: crystal structure of sulfur-free ynje 99 d1e6ca_ not modelled 29.0 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Shikimate kinase (AroK) 100 c2jtqA_ not modelled 28.6 19 PDB header:transferase Chain: A: PDB Molecule:phage shock protein e; PDBTitle: rhodanese from e.coli 101 d1umdb2 not modelled 28.2 13 Fold:TK C-terminal domain-like Superfamily:TK C-terminal domain-like Family:Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain 102 d2jfga1 not modelled 28.2 12 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 103 d1ekxa2 not modelled 28.0 13 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 104 d2bw0a2 not modelled 27.8 12 Fold:Formyltransferase Superfamily:Formyltransferase Family:Formyltransferase 105 c1s3iA_ not modelled 26.5 12 PDB header:hydrolase, oxidoreductase Chain: A: PDB Molecule:10-formyltetrahydrofolate dehydrogenase; PDBTitle: crystal structure of the n terminal hydrolase domain of 10-2 formyltetrahydrofolate dehydrogenase 106 d1meoa_ not modelled 26.1 10 Fold:Formyltransferase Superfamily:Formyltransferase Family:Formyltransferase 107 c3gk5A_ not modelled 26.0 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized rhodanese-related protein PDBTitle: crystal structure of rhodanese-related protein (tvg0868615)2 from thermoplasma volcanium, northeast structural genomics3 consortium target tvr109a 108 c1ulzA_ not modelled 25.6 29 PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase n-terminal domain; PDBTitle: crystal structure of the biotin carboxylase subunit of pyruvate2 carboxylase 109 d1dxha2 not modelled 25.6 15 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 110 d1t70a_ not modelled 25.3 20 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:DR1281-like 111 d1duvg2 not modelled 25.2 11 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 112 c3nhzA_ not modelled 24.9 27 PDB header:dna binding protein Chain: A: PDB Molecule:two component system transcriptional regulator mtra; PDBTitle: structure of n-terminal domain of mtra 113 c3nhvE_ not modelled 24.9 13 PDB header:structural genomics, unknown function Chain: E: PDB Molecule:bh2092 protein; PDBTitle: crystal structure of bh2092 protein from bacillus halodurans,2 northeast structural genomics consortium target bhr228f 114 c3aaxB_ not modelled 24.7 16 PDB header:transferase Chain: B: PDB Molecule:putative thiosulfate sulfurtransferase; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase2 cysa3 (rv3117) from mycobacterium tuberculosis: monoclinic3 form 115 d1uara2 not modelled 24.3 16 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 116 c3cm0A_ not modelled 24.1 21 PDB header:transferase Chain: A: PDB Molecule:adenylate kinase; PDBTitle: crystal structure of adenylate kinase from thermus2 thermophilus hb8 117 c3klbA_ not modelled 23.7 30 PDB header:flavoprotein Chain: A: PDB Molecule:putative flavoprotein; PDBTitle: crystal structure of putative flavoprotein in complex with fmn2 (yp_213683.1) from bacteroides fragilis nctc 9343 at 1.75 a3 resolution 118 d1rhsa1 not modelled 23.6 13 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 119 d2qmwa2 not modelled 22.9 13 Fold:Ferredoxin-like Superfamily:ACT-like Family:Phenylalanine metabolism regulatory domain 120 c2dumD_ not modelled 22.3 16 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:hypothetical protein ph0823; PDBTitle: crystal structure of hypothetical protein, ph0823

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0