Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP31675
DateThu Jan 5 11:48:32 GMT 2012
Unique Job ID0ca69579bc30f76f

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1pv7a_
Top template information
Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:LacY-like proton/sugar symporter
Confidence and coverage
Confidence:100.0% Coverage: 98%
385 residues ( 98% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MIWIMTMARRMNGVYAAFMLVAFMMGVAGALQAPTLSLFLSREVGAQPFWIGLFYTVNAI
Secondary structure 
















SS confidence 



























































Disorder  ?????????????














































Disorder confidence 



























































 
   .........70.........80.........90.........100.........110.........120
Sequence  AGIGVSLWLAKRSDSQGDRRKLIIFCCLMAIGNALLFAFNRHYLTLITCGVLLASLANTA
Secondary structure 





SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........130.........140.........150.........160.........170.........180
Sequence  MPQLFALAREYADNSAREVVMFSSVMRAQLSLAWVIGPPLAFMLALNYGFTVMFSIAAGI
Secondary structure 




SS confidence 



























































Disorder 











?


?










































Disorder confidence 



























































 
   .........190.........200.........210.........220.........230.........240
Sequence  FTLSLVLIAFMLPSVARVELPSENALSMQGGWQDSNVRMLFVASTLMWTCNTMYIIDMPL
Secondary structure 



















SS confidence 



























































Disorder 












???????????????

???


























Disorder confidence 



























































 
   .........250.........260.........270.........280.........290.........300
Sequence  WISSELGLPDKLAGFLMGTAAGLEIPAMILAGYYVKRYGKRRMMVIAVAAGVLFYTGLIF
Secondary structure 







SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........310.........320.........330.........340.........350.........360
Sequence  FNSRMALMTLQLFNAVFIGIVAGIGMLWFQDLMPGRAGAATTLFTNSISTGVILAGVIQG
Secondary structure 




SS confidence 



























































Disorder 






























?
?

?






















Disorder confidence 



























































 
   .........370.........380.........390..
Sequence  AIAQSWGHFAVYWVIAVISVVALFLTAKVKDV
Secondary structure 




SS confidence 































Disorder 



























????
Disorder confidence 































 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1pv7 chain A

3D model

Region: 7 - 391
Aligned: 385
Modelled: 385
Confidence: 100.0%
Identity: 11%
Fold: MFS general substrate transporter
Superfamily: MFS general substrate transporter
Family: LacY-like proton/sugar symporter

Phyre2

PDB 1pw4 chain A

3D model

Region: 6 - 391
Aligned: 384
Modelled: 386
Confidence: 100.0%
Identity: 14%
Fold: MFS general substrate transporter
Superfamily: MFS general substrate transporter
Family: Glycerol-3-phosphate transporter

Phyre2

PDB 2gfp chain A

3D model

Region: 16 - 383
Aligned: 365
Modelled: 368
Confidence: 100.0%
Identity: 10%
PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein d;
PDBTitle: structure of the multidrug transporter emrd from2 escherichia coli

Phyre2

PDB 3o7p chain A

3D model

Region: 13 - 391
Aligned: 375
Modelled: 379
Confidence: 100.0%
Identity: 10%
PDB header:transport protein
Chain: A: PDB Molecule:l-fucose-proton symporter;
PDBTitle: crystal structure of the e.coli fucose:proton symporter, fucp (n162a)

Phyre2

PDB 2xut chain C

3D model

Region: 18 - 389
Aligned: 372
Modelled: 372
Confidence: 100.0%
Identity: 12%
PDB header:transport protein
Chain: C: PDB Molecule:proton/peptide symporter family protein;
PDBTitle: crystal structure of a proton dependent oligopeptide (pot)2 family transporter.

Phyre2
1

d1pv7a_
2

d1pw4a_
3

c2gfpA_
4

c3o7pA_
5

c2xutC_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1pv7a_



100.0 11 Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:LacY-like proton/sugar symporter
2d1pw4a_



100.0 14 Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:Glycerol-3-phosphate transporter
3c2gfpA_



100.0 10 PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein d;
PDBTitle: structure of the multidrug transporter emrd from2 escherichia coli
4c3o7pA_



100.0 10 PDB header:transport protein
Chain: A: PDB Molecule:l-fucose-proton symporter;
PDBTitle: crystal structure of the e.coli fucose:proton symporter, fucp (n162a)
5c2xutC_



100.0 12 PDB header:transport protein
Chain: C: PDB Molecule:proton/peptide symporter family protein;
PDBTitle: crystal structure of a proton dependent oligopeptide (pot)2 family transporter.

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0