Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	E	D	L	R	A	N	S	W	S	L	R	P	C	C	M	V	L	A	Y	R	V	A	H	F	C	S	V	W	R	K	K	N	V	L	N	N	L	W	A	A	P	L	L	V	L	Y	R	I	I	T	E	C	F	F	G	Y	E	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?																																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	A	A	A	T	I	G	R	R	F	T	I	H	H	G	Y	A	V	V	I	N	K	N	V	V	A	G	D	D	F	T	I	R	H	G	V	T	I	G	N	R	G	A	D	N	M	A	C	P	H	I	G	N	G	V	E	L	G	A	N
Secondary structure
SS confidence
Disorder																																										?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.
Sequence		V	I	I	L	G	D	I	T	L	G	N	N	V	T	V	G	A	G	S	V	V	L	D	S	V	P	D	N	A	L	V	V	G	E	K	A	R	V	K	V	I	K
Secondary structure
SS confidence
Disorder																																										?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1t3d chain A Region: 19 - 160 Aligned: 142 Modelled: 142 Confidence: 100.0% Identity: 32% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Serine acetyltransferase Phyre2 PDB 1t3d chain B Region: 19 - 160 Aligned: 142 Modelled: 142 Confidence: 100.0% Identity: 32% PDB header:transferase Chain: B: PDB Molecule:serine acetyltransferase; PDBTitle: crystal structure of serine acetyltransferase from e.coli at 2.2a Phyre2 PDB 1ssq chain A Region: 19 - 158 Aligned: 140 Modelled: 140 Confidence: 100.0% Identity: 31% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Serine acetyltransferase Phyre2 PDB 3mc4 chain A Region: 19 - 158 Aligned: 135 Modelled: 140 Confidence: 100.0% Identity: 33% PDB header:transferase Chain: A: PDB Molecule:ww/rsp5/wwp domain:bacterial transferase PDBTitle: crystal structure of ww/rsp5/wwp domain: bacterial2 transferase hexapeptide repeat: serine o-acetyltransferase3 from brucella melitensis Phyre2 PDB 3f1x chain A Region: 3 - 157 Aligned: 147 Modelled: 155 Confidence: 100.0% Identity: 28% PDB header:transferase Chain: A: PDB Molecule:serine acetyltransferase; PDBTitle: three dimensional structure of the serine acetyltransferase from2 bacteroides vulgatus, northeast structural genomics consortium target3 bvr62. Phyre2 PDB 3q1x chain A Region: 4 - 151 Aligned: 144 Modelled: 148 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:serine acetyltransferase; PDBTitle: crystal structure of entamoeba histolytica serine acetyltransferase 12 in complex with l-serine Phyre2 PDB 2ic7 chain A Region: 57 - 162 Aligned: 106 Modelled: 106 Confidence: 100.0% Identity: 25% PDB header:transferase Chain: A: PDB Molecule:maltose transacetylase; PDBTitle: crystal structure of maltose transacetylase from2 geobacillus kaustophilus Phyre2 PDB 1ocx chain A Region: 22 - 160 Aligned: 139 Modelled: 139 Confidence: 100.0% Identity: 21% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Galactoside acetyltransferase-like Phyre2 PDB 3ftt chain A Region: 57 - 162 Aligned: 106 Modelled: 106 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:putative acetyltransferase sacol2570; PDBTitle: crystal structure of the galactoside o-acetyltransferase2 from staphylococcus aureus Phyre2 PDB 3ect chain A Region: 4 - 160 Aligned: 157 Modelled: 157 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:hexapeptide-repeat containing-acetyltransferase; PDBTitle: crystal structure of the hexapeptide-repeat containing-2 acetyltransferase vca0836 from vibrio cholerae Phyre2 PDB 3srt chain B Region: 57 - 162 Aligned: 106 Modelled: 106 Confidence: 99.9% Identity: 30% PDB header:transferase Chain: B: PDB Molecule:maltose o-acetyltransferase; PDBTitle: the crystal structure of a maltose o-acetyltransferase from2 clostridium difficile 630 Phyre2 PDB 1krr chain A Region: 56 - 160 Aligned: 105 Modelled: 105 Confidence: 99.9% Identity: 30% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Galactoside acetyltransferase-like Phyre2 PDB 1mr7 chain A Region: 58 - 162 Aligned: 105 Modelled: 105 Confidence: 99.9% Identity: 25% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Galactoside acetyltransferase-like Phyre2 PDB 3cj8 chain B Region: 57 - 161 Aligned: 103 Modelled: 105 Confidence: 99.9% Identity: 38% PDB header:transferase Chain: B: PDB Molecule:2,3,4,5-tetrahydropyridine-2-carboxylate n- PDBTitle: crystal structure of 2,3,4,5-tetrahydropyridine-2-carboxylate n-2 succinyltransferase from enterococcus faecalis v583 Phyre2 PDB 3eev chain C Region: 60 - 162 Aligned: 103 Modelled: 103 Confidence: 99.9% Identity: 19% PDB header:transferase Chain: C: PDB Molecule:chloramphenicol acetyltransferase; PDBTitle: crystal structure of chloramphenicol acetyltransferase vca0300 from2 vibrio cholerae o1 biovar eltor Phyre2 PDB 1xat chain A Region: 60 - 162 Aligned: 103 Modelled: 103 Confidence: 99.9% Identity: 26% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Galactoside acetyltransferase-like Phyre2 PDB 3r0s chain A Region: 57 - 161 Aligned: 103 Modelled: 105 Confidence: 99.9% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o- PDBTitle: udp-n-acetylglucosamine acyltransferase from campylobacter jejuni Phyre2 PDB 1j2z chain A Region: 57 - 161 Aligned: 103 Modelled: 105 Confidence: 99.9% Identity: 22% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: UDP N-acetylglucosamine acyltransferase Phyre2 PDB 3i3a chain C Region: 57 - 162 Aligned: 104 Modelled: 106 Confidence: 99.9% Identity: 21% PDB header:transferase Chain: C: PDB Molecule:acyl-[acyl-carrier-protein]--udp-n- PDBTitle: structural basis for the sugar nucleotide and acyl chain2 selectivity of leptospira interrogans lpxa Phyre2 PDB 2jf2 chain A domain 1 Region: 57 - 161 Aligned: 103 Modelled: 105 Confidence: 99.9% Identity: 22% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: UDP N-acetylglucosamine acyltransferase Phyre2 1 d1t3da_ 2 c1t3dB_ 3 d1ssqa_ 4 c3mc4A_ 5 c3f1xA_ 6 c3q1xA_ 7 c2ic7A_ 8 d1ocxa_ 9 c3fttA_ 10 c3ectA_ 11 c3srtB_ 12 d1krra_ 13 d1mr7a_ 14 c3cj8B_ 15 c3eevC_ 16 d1xata_ 17 c3r0sA_ 18 d1j2za_ 19 c3i3aC_ 20 d2jf2a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1t3da_ 100.0 32 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:Serine acetyltransferase 2 c1t3dB_ 100.0 32 PDB header:transferase Chain: B: PDB Molecule:serine acetyltransferase; PDBTitle: crystal structure of serine acetyltransferase from e.coli at 2.2a 3 d1ssqa_ 100.0 31 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:Serine acetyltransferase 4 c3mc4A_ 100.0 33 PDB header:transferase Chain: A: PDB Molecule:ww/rsp5/wwp domain:bacterial transferase PDBTitle: crystal structure of ww/rsp5/wwp domain: bacterial2 transferase hexapeptide repeat: serine o-acetyltransferase3 from brucella melitensis 5 c3f1xA_ 100.0 28 PDB header:transferase Chain: A: PDB Molecule:serine acetyltransferase; PDBTitle: three dimensional structure of the serine acetyltransferase from2 bacteroides vulgatus, northeast structural genomics consortium target3 bvr62. 6 c3q1xA_ 100.0 27 PDB header:transferase Chain: A: PDB Molecule:serine acetyltransferase; PDBTitle: crystal structure of entamoeba histolytica serine acetyltransferase 12 in complex with l-serine 7 c2ic7A_ 100.0 25 PDB header:transferase Chain: A: PDB Molecule:maltose transacetylase; PDBTitle: crystal structure of maltose transacetylase from2 geobacillus kaustophilus 8 d1ocxa_ 100.0 21 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:Galactoside acetyltransferase-like 9 c3fttA_ 100.0 26 PDB header:transferase Chain: A: PDB Molecule:putative acetyltransferase sacol2570; PDBTitle: crystal structure of the galactoside o-acetyltransferase2 from staphylococcus aureus 10 c3ectA_ 100.0 21 PDB header:transferase Chain: A: PDB Molecule:hexapeptide-repeat containing-acetyltransferase; PDBTitle: crystal structure of the hexapeptide-repeat containing-2 acetyltransferase vca0836 from vibrio cholerae 11 c3srtB_ 99.9 30 PDB header:transferase Chain: B: PDB Molecule:maltose o-acetyltransferase; PDBTitle: the crystal structure of a maltose o-acetyltransferase from2 clostridium difficile 630 12 d1krra_ 99.9 30 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:Galactoside acetyltransferase-like 13 d1mr7a_ 99.9 25 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:Galactoside acetyltransferase-like 14 c3cj8B_ 99.9 38 PDB header:transferase Chain: B: PDB Molecule:2,3,4,5-tetrahydropyridine-2-carboxylate n- PDBTitle: crystal structure of 2,3,4,5-tetrahydropyridine-2-carboxylate n-2 succinyltransferase from enterococcus faecalis v583 15 c3eevC_ 99.9 19 PDB header:transferase Chain: C: PDB Molecule:chloramphenicol acetyltransferase; PDBTitle: crystal structure of chloramphenicol acetyltransferase vca0300 from2 vibrio cholerae o1 biovar eltor 16 d1xata_ 99.9 26 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:Galactoside acetyltransferase-like 17 c3r0sA_ 99.9 20 PDB header:transferase Chain: A: PDB Molecule:acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o- PDBTitle: udp-n-acetylglucosamine acyltransferase from campylobacter jejuni 18 d1j2za_ 99.9 22 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:UDP N-acetylglucosamine acyltransferase 19 c3i3aC_ 99.9 21 PDB header:transferase Chain: C: PDB Molecule:acyl-[acyl-carrier-protein]--udp-n- PDBTitle: structural basis for the sugar nucleotide and acyl chain2 selectivity of leptospira interrogans lpxa 20 d2jf2a1 99.9 22 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:UDP N-acetylglucosamine acyltransferase 21 c3jqyB_ not modelled 99.9 23 PDB header:transferase Chain: B: PDB Molecule:polysialic acid o-acetyltransferase; PDBTitle: crystal strucutre of the polysia specific acetyltransferase neuo 22 c2wlgA_ not modelled 99.9 30 PDB header:transferase Chain: A: PDB Molecule:polysialic acid o-acetyltransferase; PDBTitle: crystallographic analysis of the polysialic acid o-2 acetyltransferase oatwy 23 c2iu9C_ not modelled 99.9 27 PDB header:transferase Chain: C: PDB Molecule:udp-3-o-[3-hydroxymyristoyl] glucosamine PDBTitle: chlamydia trachomatis lpxd with 100mm udpglcnac (complex ii) 24 c3mqhD_ not modelled 99.9 35 PDB header:transferase Chain: D: PDB Molecule:lipopolysaccharides biosynthesis acetyltransferase; PDBTitle: crystal structure of the 3-n-acetyl transferase wlbb from bordetella2 petrii in complex with coa and udp-3-amino-2-acetamido-2,3-dideoxy3 glucuronic acid 25 d3bswa1 not modelled 99.9 20 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:PglD-like 26 d1g97a1 not modelled 99.9 25 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:GlmU C-terminal domain-like 27 c3fsbB_ not modelled 99.9 43 PDB header:transferase Chain: B: PDB Molecule:qdtc; PDBTitle: crystal structure of qdtc, the dtdp-3-amino-3,6-dideoxy-d-2 glucose n-acetyl transferase from thermoanaerobacterium3 thermosaccharolyticum in complex with coa and dtdp-3-amino-4 quinovose 28 c1hm8A_ not modelled 99.8 28 PDB header:transferase Chain: A: PDB Molecule:udp-n-acetylglucosamine-1-phosphate uridyltransferase; PDBTitle: crystal structure of s.pneumoniae n-acetylglucosamine-1-phosphate2 uridyltransferase, glmu, bound to acetyl coenzyme a 29 c3pmoA_ not modelled 99.8 27 PDB header:transferase Chain: A: PDB Molecule:udp-3-o-[3-hydroxymyristoyl] glucosamine n-acyltransferase; PDBTitle: the structure of lpxd from pseudomonas aeruginosa at 1.3 a resolution 30 c2v0hA_ not modelled 99.8 25 PDB header:transferase Chain: A: PDB Molecule:bifunctional protein glmu; PDBTitle: characterization of substrate binding and catalysis of the2 potential antibacterial target n-acetylglucosamine-1-3 phosphate uridyltransferase (glmu) 31 d2oi6a1 not modelled 99.8 28 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:GlmU C-terminal domain-like 32 c3eh0C_ not modelled 99.8 30 PDB header:transferase Chain: C: PDB Molecule:udp-3-o-[3-hydroxymyristoyl] glucosamine n- PDBTitle: crystal structure of lpxd from escherichia coli 33 c2oi6A_ not modelled 99.8 23 PDB header:transferase Chain: A: PDB Molecule:bifunctional protein glmu; PDBTitle: e. coli glmu- complex with udp-glcnac, coa and glcn-1-po4 34 c3eg4A_ not modelled 99.8 15 PDB header:transferase Chain: A: PDB Molecule:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate n- PDBTitle: crystal structure of 2,3,4,5-tetrahydropyridine-2-2 carboxylate n-succinyltransferase from brucella melitensis3 biovar abortus 2308 35 c3ixcA_ not modelled 99.8 17 PDB header:transferase Chain: A: PDB Molecule:hexapeptide transferase family protein; PDBTitle: crystal structure of hexapeptide transferase family protein from2 anaplasma phagocytophilum 36 d3tdta_ not modelled 99.8 16 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD 37 d1v3wa_ not modelled 99.7 24 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:gamma-carbonic anhydrase-like 38 d1xhda_ not modelled 99.7 26 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:gamma-carbonic anhydrase-like 39 c3r1wA_ not modelled 99.7 23 PDB header:lyase Chain: A: PDB Molecule:carbonic anhydrase; PDBTitle: crystal structure of a carbonic anhydrase from a crude oil degrading2 psychrophilic library 40 c3fsyC_ not modelled 99.7 26 PDB header:transferase Chain: C: PDB Molecule:tetrahydrodipicolinate n-succinyltransferase; PDBTitle: structure of tetrahydrodipicolinate n-succinyltransferase2 (rv1201c;dapd) in complex with succinyl-coa from mycobacterium3 tuberculosis 41 c3r3rA_ not modelled 99.7 22 PDB header:transferase Chain: A: PDB Molecule:ferripyochelin binding protein; PDBTitle: structure of the yrda ferripyochelin binding protein from salmonella2 enterica 42 c2ggqA_ not modelled 99.7 21 PDB header:transferase Chain: A: PDB Molecule:401aa long hypothetical glucose-1-phosphate PDBTitle: complex of hypothetical glucose-1-phosphate thymidylyltransferase from2 sulfolobus tokodaii 43 c3c8vA_ not modelled 99.6 17 PDB header:transferase Chain: A: PDB Molecule:putative acetyltransferase; PDBTitle: crystal structure of putative acetyltransferase (yp_390128.1) from2 desulfovibrio desulfuricans g20 at 2.28 a resolution 44 c1qreA_ not modelled 99.4 24 PDB header:lyase Chain: A: PDB Molecule:carbonic anhydrase; PDBTitle: a closer look at the active site of gamma-carbonic anhydrases: high2 resolution crystallographic studies of the carbonic anhydrase from3 methanosarcina thermophila 45 d1qrea_ not modelled 99.4 24 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:gamma-carbonic anhydrase-like 46 d2f9ca1 not modelled 99.2 14 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:YdcK-like 47 c2rijA_ not modelled 99.2 26 PDB header:transferase Chain: A: PDB Molecule:putative 2,3,4,5-tetrahydropyridine-2-carboxylate n- PDBTitle: crystal structure of a putative 2,3,4,5-tetrahydropyridine-2-2 carboxylate n-succinyltransferase (cj1605c, dapd) from campylobacter3 jejuni at 1.90 a resolution 48 c2qkxA_ not modelled 99.1 19 PDB header:transferase Chain: A: PDB Molecule:bifunctional protein glmu; PDBTitle: n-acetyl glucosamine 1-phosphate uridyltransferase from mycobacterium2 tuberculosis complex with n-acetyl glucosamine 1-phosphate 49 c3d98A_ not modelled 99.0 18 PDB header:transferase Chain: A: PDB Molecule:bifunctional protein glmu; PDBTitle: crystal structure of glmu from mycobacterium tuberculosis, ligand-free2 form 50 d1yp2a1 not modelled 99.0 16 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:GlmU C-terminal domain-like 51 c3kwdA_ not modelled 99.0 20 PDB header:lyase, protein binding, photosynthesis Chain: A: PDB Molecule:carbon dioxide concentrating mechanism protein; PDBTitle: inactive truncation of the beta-carboxysomal gamma-carbonic anhydrase,2 ccmm, form 1 52 d1fxja1 not modelled 99.0 27 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:GlmU C-terminal domain-like 53 c1yp3C_ not modelled 98.8 14 PDB header:transferase Chain: C: PDB Molecule:glucose-1-phosphate adenylyltransferase small PDBTitle: crystal structure of potato tuber adp-glucose2 pyrophosphorylase in complex with atp 54 c1fwyA_ not modelled 98.7 22 PDB header:transferase Chain: A: PDB Molecule:udp-n-acetylglucosamine pyrophosphorylase; PDBTitle: crystal structure of n-acetylglucosamine 1-phosphate2 uridyltransferase bound to udp-glcnac 55 c3brkX_ not modelled 98.5 14 PDB header:transferase Chain: X: PDB Molecule:glucose-1-phosphate adenylyltransferase; PDBTitle: crystal structure of adp-glucose pyrophosphorylase from2 agrobacterium tumefaciens 56 d2icya1 not modelled 30.7 34 Fold:Single-stranded left-handed beta-helix Superfamily:Trimeric LpxA-like enzymes Family:GlmU C-terminal domain-like 57 d2z1ca1 not modelled 6.4 21 Fold:OB-fold Superfamily:HupF/HypC-like Family:HupF/HypC-like 58 c1dvaY_ not modelled 5.8 30 PDB header:hydrolase/hydrolase inhibitor Chain: Y: PDB Molecule:peptide e-76; PDBTitle: crystal structure of the complex between the peptide exosite inhibitor2 e-76 and coagulation factor viia 59 c1dvaX_ not modelled 5.8 30 PDB header:hydrolase/hydrolase inhibitor Chain: X: PDB Molecule:peptide e-76; PDBTitle: crystal structure of the complex between the peptide exosite inhibitor2 e-76 and coagulation factor viia

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0