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| Protein Homology/analogY Recognition Engine V 2.2 | ||||||||
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gives you access to our Expert Mode
features.
Phyre2-ligand βWe are pleased to announce the β-release of a new feature - Phyre2-ligandIt is available through buttons that are next to those for Phyre-investigator for the top 20 results from a Phyre2.2 run in Normal and Intensive mode. We hope to make it available in the near future for jobs run in One-to-One and AlphaThread modes |
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One-to-One Threading |
Please do not use "intensive mode" unless your search using "normal mode" indicates that a
single model does not cover most of your sequence. ![]()
| E-mail address: | |||
| Optional Job description | |||
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or
upload contents of sequence file
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or
UniProt accession
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Modelling Mode
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Please tick as appropriate.
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Examples of running Phyre2.2 on UniProt accession P0DV45 in
Normal,
Intensive
and
AlphaThread
modes
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| Missense3D Portal: | a suite of resources for the analysis of amino acid substitutions in proteins |
| GWYRE: | contains modeled and experimentally determined structures of human proteins and protein complexes, annotated by phenotypic effects of genetic mutations. |
Phyre is now FREE for commercial users!
All images and data generated by Phyre2 are free to use in any publication with acknowledgement
Accessibility Statement| Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction | |||||||||
| Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960 | |||||||||
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