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Protein Homology/analogY Recognition Engine V 2.2 |
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gives you access to our Expert Mode
features.
I recommend that people do not submit any jobs that are likely to be running when the system is scheduled to be unavailable. Any finished jobs will be available again once the system is up and running (it's possible that the webserver will not be affected, so you might be able to access these jobs). |
We are pleased to announce the release of Phyre2.2, which contains a number of new features
(see the help menu for more details).
If you really need to use the old version, checking the "Traditional Phyre2" button will allow this. |
One-to-One Threading![]() ![]() |
Please do not use "intensive mode" unless your search using "normal mode" indicates that a
single model does not cover most of your sequence.
E-mail address: | |||
Optional Job description | |||
or
upload contents of sequence file
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or
UniProt accession
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Modelling Mode
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Please tick as appropriate.
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Examples of running Phyre2.2 on UniProt accession P0DV45 in
Normal,
Intensive
and
AlphaThread
modes
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Missense3D Portal: | a suite of resources for the analysis of amino acid substitutions in proteins |
GWYRE: | contains modeled and experimentally determined structures of human proteins and protein complexes, annotated by phenotypic effects of genetic mutations. |
Phyre is now FREE for commercial users!
All images and data generated by Phyre2 are free to use in any publication with acknowledgement
Accessibility StatementPlease cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction | |||||||||
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960 | |||||||||
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