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Protein Homology/analogY Recognition Engine V 2.2 |
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We are pleased to announce the release of Phyre2.2, which contains a number of new features
(see the help menu for more details).
If you really need to use the old version, checking the "Traditional Phyre2" button will allow this. |
One-to-One Threading![]() ![]() |
Please do not use "intensive mode" unless your search using "normal mode" indicates that a
single model does not cover most of your sequence.
E-mail address: | |||
Optional Job description | |||
or
upload contents of sequence file
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or
UniProt accession
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Modelling Mode
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Please tick as appropriate.
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Examples of running Phyre2.2 on UniProt accession P0DV45 in
Normal,
Intensive
and
AlphaThread
modes
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Missense3D Portal: | a suite of resources for the analysis of amino acid substitutions in proteins |
GWYRE: | contains modeled and experimentally determined structures of human proteins and protein complexes, annotated by phenotypic effects of genetic mutations. |
Phyre is now FREE for commercial users!
All images and data generated by Phyre2 are free to use in any publication with acknowledgement
Accessibility StatementPlease cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction | |||||||||
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960 | |||||||||
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