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| Protein Homology/analogY Recognition Engine V 2.0 | ||||||
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| Protein Homology/analogY Recognition Engine V 2.0 | ||||||
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The Phyre2.2 webserver has been developed by Harry Powell from the Phyre2 webserver which was designed and written by Dr Lawrence Kelley Phyre2 is the successor to the two web servers that Lawrence previously developed, 3D-pssm and Phyre. Phyre2 was ranked amongst the best systems of its kind as judged by the biannual Critical Assessment of Structure Prediction (CASP) meetings, prior to the release of the original AlphaFold in 2018. The work on developing the Phyre2 web server is supported by a BBSRC tools and resources grant
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| Component software |
| Template detection: HHpred 1.51 DOI: 10.1093/bioinformatics/bti125 |
| Secondary structure prediction: Psi-pred 3.5 DOI: 10.1006/jmbi.1999.3091 |
| Disorder prediction: Disopred 2.4 DOI: 10.1016/j.jmb.2004.02.002 |
| Transmembrane prediction: Memsat_SVM DOI: 10.1093/bioinformatics/btl677 |
| Multi-template modelling and ab initio: Poing 1.0 DOI: 10.1016/j.jmb.2010.01.074 |
Phyre is now FREE for commercial users!
All images and data generated by Phyre2 are free to use in any publication with acknowledgement
Accessibility Statement| Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction | |||||||||
| Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960 | |||||||||
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