| ||Protein Homology/analogY Recognition Engine V 2.0|
Please do not use 'intensive mode' unless you are an experienced user and understand its pitfalls (and your search has already failed with 'normal mode'). For most users, most of the time, 'normal mode' will give you the answer you require
If you have more than 5 or 6 sequences to model, it is easier for you (and better for everyone!) if you use "batch" mode, which is available under the Expert Mode after you log in (top left of the interface). If you haven't registered for a Login, you can do so on the Login page.
4760736 submissions since Feb 14 2011
Missense3D: Analyse structural impact of missense variants
PhyreRisk: A dynamic database to view human sequences and structures and map genetic variants
Cambridge 2019 Workshop | Older Workshops | Phyre2 paper
Half of the human population has a defective TMPRSS2 protein that significantly reduces the chance of developing severe COVID-19: read our preprint at https://doi.org/10.1101/2021.03.04.21252931
If you are interested in joining the Phyre development team, please contact Prof. Michael Sternberg for further information.
Phyre is now FREE for commercial users!
All images and data generated by Phyre2 are free to use in any publication with acknowledgementAccessibility Statement
|Please cite: The Phyre2 web portal for protein modeling, prediction and analysis|
|Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]|