Covid-19 news
Half of the human population has a defective TMPRSS2 protein that significantly reduces the chance of developing severe COVID-19: read our preprint at https://doi.org/10.1101/2021.03.04.21252931
Position opening
If you are interested in joining the Phyre development team, please contact Prof. Michael Sternberg for further information.
Other Resources
Missense3D: Analyse structural impact of missense variants
PhyreRisk: A dynamic database to view human sequences and structures and map genetic variants
Cambridge 2019 Workshop | Older Workshops | Phyre2 paper
Please do not use 'intensive mode' unless you are an experienced user and understand its pitfalls (and your search has already failed with 'normal mode'). For most users, most of the time, 'normal mode' will give you the answer you require
Type a gene name, GI number, Uniprot code, free text etc. More..
A search is also performed on the sequence descriptor line. Please note the list of available identifiers is not exhaustive as there are so many naming conventions in use. However, hopefully you'll find what you're looking for.
e.g. BRCA1, tafazzin homo sapiens, A0EM47
If you come across what you consider to be clear omissions from the database, please let me know: Harry Powell
