Log in (top left-hand corner of this web page) to use our Expert Mode features, including batch job submission
and One-to-One threading. Registering for this is quick and easy on our Login page .
You can use "One-to-One Threading" to model your
sequence against your own in-house structures and those from the Protein Data Bank, as well as models downloaded from the AlphaFold Protein Structure Database.
If you have more than 5 or 6 sequences to model, it is easier for you (and better for everyone!) if you
use "batch" processing (under Expert Mode).
Please do not use "intensive mode" unless your search using "normal mode" indicates that a single model does not cover most of your sequence. For most users, most of the time, 'normal mode'
will give you the answer you require in a fraction of the time.
Current Phyre2 server load = 3% (normal running)
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