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 Protein Homology/analogY Recognition Engine V 2.0


 

New fold library entries added 2013 Feb 16

Fold library idPDB HeaderMoleculeTitle
c4he8M_ oxidoreductase Chain: M: nadh-quinone oxidoreductase subunit 13; crystal structure of the membrane domain of respiratory complex i from2 thermus thermophilus
c4dpgK_ ligase/apoptosis Chain: K: aminoacyl trna synthase complex-interacting multifunctional crystal structure of human lysrs: p38/aimp2 complex i
c4bduC_ apoptosis Chain: C: green fluorescent protein, apoptosis regulator bax; bax bh3-in-groove dimer (gfp)
c4i66A_ structural genomics, unknown function Chain: A: uncharacterized protein hoch_4089; crystal structure of hoch_4089 protein from haliangium ochraceum
c4i6mD_ transcription/hydrolase Chain: D: regulator of ty1 transposition protein 102; structure of arp7-arp9-snf2(hsa)-rtt102 subcomplex of swi/snf2 chromatin remodeler.
c4hw9E_ membrane protein Chain: E: mechanosensitive channel mscs; crystal structure of helicobacter pylori mscs (closed state)
c3zeyE_ ribosome Chain: E: 40s ribosomal proteins s11, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4geeA_ isomerase/isomerase inhibitor Chain: A: dna gyrase subunit b; pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv,2 part i: structure guided discovery and optimization of dual targeting3 agents with potent, broad-spectrum enzymatic activity.
c3zf7t_ ribosome Chain: T: 60s ribosomal protein l19, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zey9_ ribosome Chain: 9: ubiquitin/ribosomal protein s27a, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4isdA_ transferase Chain: A: glutathione s-transferase; crystal structure of glutathione transferase homolog from burkholderia2 gl bgr1, target efi-501803, with bound glutathione
c4he8H_ oxidoreductase Chain: H: nadh-quinone oxidoreductase subunit 8; crystal structure of the membrane domain of respiratory complex i from2 thermus thermophilus
c4h13H_ photosynthesis Chain: H: cytochrome b6-f complex subunit 8; crystal structure of the cytochrome b6f complex from mastigocladus2 laminosus with tds
c3zf7a_ ribosome Chain: A: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4heaT_ oxidoreductase Chain: T: nadh-quinone oxidoreductase subunit 12; crystal structure of the entire respiratory complex i from thermus2 thermophilus
c4igdA_ hydrolase Chain: A: mannan-binding lectin serine protease 1; crystal structure of the zymogen catalytic region of human masp-1
c3zf7u_ ribosome Chain: U: 60s ribosomal protein l21e, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zeyQ_ ribosome Chain: Q: ribosomal protein s20, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4hymA_ isomerase/isomerase inhibitor Chain: A: topoisomerase iv, subunit b; pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv,2 part i: structure guided discovery and optimization of dual targeting3 agents with potent, broad-spectrum enzymatic activity.
c4heaJ_ oxidoreductase Chain: J: nadh-quinone oxidoreductase subunit 10; crystal structure of the entire respiratory complex i from thermus2 thermophilus
c4iw7A_ transferase Chain: A: 8-amino-7-oxononanoate synthase; crystal structure of 8-amino-7-oxononanoate synthase (biof) from2 francisella tularensis.
c3zf7K_ ribosome Chain: K: 60s ribosomal protein l10, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4b91B_ signaling protein Chain: B: dihydropyrimidinase-related protein 5; crystal structure of truncated human crmp-5
c4doyE_ oxidoreductase Chain: E: dibenzothiophene desulfurization enzyme c; crystal structure of dibenzothiophene desulfurization enzyme c
c3zeyI_ ribosome Chain: I: 40s ribosomal protein s15, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4devE_ hydrolase Chain: E: acetyl-xylan esterase est2a; an acetyl xylan esterase (est2a) from the rumen bacterium butyrivibrio2 proteoclasticus.
c3zeyX_ ribosome Chain: X: 40s ribosomal protein s3, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4hyrB_ lyase Chain: B: glucarate dehydratase; structure of putative glucarate dehydratase from acidaminococcus sp.2 d21 with unusual static disorder
c3zf7b_ ribosome Chain: B: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7i_ ribosome Chain: I: 60s ribosomal protein l18; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4heaK_ oxidoreductase Chain: K: nadh-quinone oxidoreductase subunit 11; crystal structure of the entire respiratory complex i from thermus2 thermophilus
c4ivfH_ transferase Chain: H: putative uncharacterized protein; crystal structure of glutathione transferase homolog from lodderomyces2 elongisporus, target efi-501753, with two gsh per subunit
c3zf7L_ ribosome Chain: L: 60s ribosomal protein l11, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zeyW_ ribosome Chain: W: 40s ribosomal protein s27, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4bdwA_ hydrolase Chain: A: coagulation factor xiia heavy chain; the stucture of the fni-egf tandem domain of coagulation factor xii2 in complex with holmium
c3zf7g_ ribosome Chain: G: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4ii3A_ ligase Chain: A: ubiquitin-activating enzyme e1 1; crystal structure of s. pombe ubiquitin activating enzyme 1 (uba1) in2 complex with ubiquitin and atp/mg
c4di7A_ oxidoreductase Chain: A: amphi; structure of a2-type ketoreductase of modular polyketide synthases
c3zeyL_ ribosome Chain: L: 40s ribosomal protein s17, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4h0lH_ photosynthesis Chain: H: cytochrome b6-f complex subunit 8; cytochrome b6f complex crystal structure from mastigocladus laminosus2 with n-side inhibitor nqno
c2m47A_ structural genomics, unknown function Chain: A: uncharacterized protein cgl2373; solution nmr structure of the polyketide_cyc-like protein cgl2372 from2 corynebacterium glutamicum, northeast structural genomics consortium3 target cgr160
c4efcA_ lyase Chain: A: adenylosuccinate lyase; crystal structure of adenylosuccinate lyase from trypanosoma brucei,2 tb427tmp.160.5560
c3vepA_ membrane protein/transcription Chain: A: probable rna polymerase sigma-d factor; crystal structure of sigd4 in complex with its negative regulator rsda
c4gu0E_ oxidoreductase Chain: E: histone h3.3; crystal structure of lsd2 with h3
c3zf7I_ ribosome Chain: I: 60s ribosomal protein l18; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7O_ ribosome Chain: O: 60s ribosomal protein l13a, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7Y_ ribosome Chain: Y: 60s ribosomal protein l24, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3vepX_ membrane protein/transcription Chain: X: uncharacterized protein rv3413c/mt3522; crystal structure of sigd4 in complex with its negative regulator rsda
c3zf7v_ ribosome Chain: V: 60s ribosomal protein l22, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7h_ ribosome Chain: H: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zeyZ_ ribosome Chain: Z: 40s ribosomal protein s33, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zeyT_ ribosome Chain: T: 40s ribosomal protein s24; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zdlB_ cell adhesion Chain: B: amyloid beta a4 precursor protein-binding family b member vinculin head (1-258) in complex with a riam fragment
c3v9mB_ hydrolase Chain: B: phospholipase a2 isozyme pa-11; phospholipase acii4 from australian king brown snake
c4id2B_ structural genomics, unknown function Chain: B: uncharacterized protein; crystal structure of a hypothetical protein (bacova_05496) from2 bacteroides ovatus atcc 8483 at 2.15 a resolution
c3zeyC_ ribosome Chain: C: 40s ribosomal protein sa, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7U_ ribosome Chain: U: 60s ribosomal protein l21e, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4iumA_ hydrolase/protein binding Chain: A: papain-like protease 2; equine arteritis virus papain-like protease 2 (plp2) covalently bound2 to ubiquitin
c2lqgA_ cell adhesion, structural protein Chain: A: talin-1; solution structure of the r4 domain of talin
c4heaO_ oxidoreductase Chain: O: nadh-quinone oxidoreductase subunit 9; crystal structure of the entire respiratory complex i from thermus2 thermophilus
c4i6mA_ transcription/hydrolase Chain: A: actin-related protein 7; structure of arp7-arp9-snf2(hsa)-rtt102 subcomplex of swi/snf2 chromatin remodeler.
c4dpgJ_ ligase/apoptosis Chain: J: aminoacyl trna synthase complex-interacting multifunctional crystal structure of human lysrs: p38/aimp2 complex i
c3zf7w_ ribosome Chain: W: 60s ribosomal protein l23, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4he8B_ oxidoreductase Chain: B: nadh-quinone oxidoreductase subunit 7; crystal structure of the membrane domain of respiratory complex i from2 thermus thermophilus
c4if8B_ hydrolase inhibitor Chain: B: serpin a12; structure of vaspin
c3zeyK_ ribosome Chain: K: 40s ribosomal protein s16, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7m_ ribosome Chain: M: 60s ribosomal protein l12, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zey8_ ribosome Chain: 8: ribosomal protein s29, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4fczB_ transport protein Chain: B: toluene-tolerance protein; crystal structure of toluene-tolerance protein from pseudomonas putida2 (strain kt2440), northeast structural genomics consortium (nesg)3 target ppr99
c3zeyF_ ribosome Chain: F: 40s ribosomal protein s12; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4ii1A_ transcription Chain: A: zinc finger ccch-type with g patch domain-containing crystal structure of the zinc finger of zgpat
c3zeyY_ ribosome Chain: Y: 40s ribosomal protein s30, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3ziaJ_ hydrolase Chain: J: atpase inhibitor, mitochondrial; the structure of f1-atpase from saccharomyces cerevisiae2 inhibited by its regulatory protein if1
c3zf7X_ ribosome Chain: X: 60s ribosomal protein l23a; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zey7_ ribosome Chain: 7: guanine nucleotide-binding protein beta subunit-like high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7Z_ ribosome Chain: Z: 60s ribosomal protein l26, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7J_ ribosome Chain: J: ribosomal protein; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zey6_ ribosome Chain: 6: 40s ribosomal protein s9, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7e_ ribosome Chain: E: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4hxdB_ hydrolase/viral protein Chain: B: rna-directed rna polymerase l; diversity of ubiquitin and isg15 specificity amongst nairoviruses2 viral ovarian tumor domain proteases
c3zeyV_ ribosome Chain: V: ribosomal protein s26, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4he8I_ oxidoreductase Chain: I: nadh-quinone oxidoreductase subunit 14; crystal structure of the membrane domain of respiratory complex i from2 thermus thermophilus
c3zf7x_ ribosome Chain: X: 60s ribosomal protein l23a; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7M_ ribosome Chain: M: 60s ribosomal protein l12, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7k_ ribosome Chain: K: 60s ribosomal protein l10, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7n_ ribosome Chain: N: 60s ribosomal protein l13; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4h13E_ photosynthesis Chain: E: cytochrome b6-f complex subunit 6; crystal structure of the cytochrome b6f complex from mastigocladus2 laminosus with tds
c3vepC_ membrane protein/transcription Chain: C: uncharacterized protein rv3413c/mt3522; crystal structure of sigd4 in complex with its negative regulator rsda
c4iyqB_ protein binding Chain: B: divalent ion tolerance protein cuta1; crystal structure of divalent ion tolerance protein cuta1 from2 ehrlichia chaffeensis
c4hsuC_ oxidoreductase Chain: C: histone h3; crystal structure of lsd2-npac with h3(1-26)in space group p21
c3zey5_ ribosome Chain: 5: 40s ribosomal protein s8; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zey0_ ribosome Chain: 0: 40s ribosomal protein s3a, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7q_ ribosome Chain: Q: ribosomal protein l15; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zeyS_ ribosome Chain: S: 40s ribosomal protein s23, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zeyM_ ribosome Chain: M: 40s ribosomal protein s18, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7f_ ribosome Chain: F: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4h0lE_ photosynthesis Chain: E: cytochrome b6-f complex subunit 6; cytochrome b6f complex crystal structure from mastigocladus laminosus2 with n-side inhibitor nqno
c3zf7P_ ribosome Chain: P: probable 60s ribosomal protein l14; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c2m3kA_ motor protein Chain: A: minor pilin comp; global fold of the type iv pilin comp from neisseria meningitidis
c4ijdA_ transferase Chain: A: histone-lysine n-methyltransferase prdm9; crystal structure of methyltransferase domain of human pr domain-2 containing protein 9
c3zf7l_ ribosome Chain: L: 60s ribosomal protein l11, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7c_ ribosome Chain: C: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zey4_ ribosome Chain: 4: ribosomal protein s7, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7V_ ribosome Chain: V: 60s ribosomal protein l22, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3vqzA_ hydrolase/hydrolase inhibitor Chain: A: metallo-beta-lactamase; crystal structure of metallo-beta-lactamase, smb-1, in a complex with2 mercaptoacetic acid
c4i6mC_ transcription/hydrolase Chain: C: actin-like protein arp9; structure of arp7-arp9-snf2(hsa)-rtt102 subcomplex of swi/snf2 chromatin remodeler.
c3zf7o_ ribosome Chain: O: 60s ribosomal protein l13a, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4dg3A_ transferase/transferase inhibitor Chain: A: camp-dependent protein kinase inhibitor alpha; crystal structure of r336a mutant of camp-dependent protein kinase2 with unphosphorylated turn motif.
c3zey1_ ribosome Chain: 1: 40s ribosomal protein s4, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7R_ ribosome Chain: R: 60s ribosomal protein l17, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7r_ ribosome Chain: R: 60s ribosomal protein l17, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4ic7B_ transferase Chain: B: dual specificity mitogen-activated protein kinase kinase 5; crystal structure of the erk5 kinase domain in complex with an mkk52 binding fragment
c3zeyD_ ribosome Chain: D: 40s ribosomal protein s10, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zeyP_ ribosome Chain: P: 40s ribosomal protein s2, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4idlA_ immune system Chain: A: single domain antibody vhh a9; low melting temperature anti-cholera toxin llama vhh domain
c3zey3_ ribosome Chain: 3: 40s ribosomal protein s6; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3uleB_ structural protein Chain: B: actin-related protein 2; structure of bos taurus arp2/3 complex with bound inhibitor ck-869 and2 atp
c3ziaT_ hydrolase Chain: T: atpase inhibitor, mitochondrial; the structure of f1-atpase from saccharomyces cerevisiae2 inhibited by its regulatory protein if1
c4i6mB_ transcription/hydrolase Chain: B: actin-like protein arp9; structure of arp7-arp9-snf2(hsa)-rtt102 subcomplex of swi/snf2 chromatin remodeler.
c4gu0F_ oxidoreductase Chain: F: histone h3.3; crystal structure of lsd2 with h3
c4iwhA_ oxidoreductase Chain: A: 3-isopropylmalate dehydrogenase; crystal structure of a 3-isopropylmalate dehydrogenase from2 burkholderia pseudomallei
c3zf7y_ ribosome Chain: Y: 60s ribosomal protein l24, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3w3sA_ ligase/rna Chain: A: type-2 serine--trna ligase; crystal structure of a. aeolicus trnasec in complex with m. kandleri2 serrs
c3zeyG_ ribosome Chain: G: 40s ribosomal protein s13, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7S_ ribosome Chain: S: 60s ribosomal protein l18a; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7p_ ribosome Chain: P: probable 60s ribosomal protein l14; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zey2_ ribosome Chain: 2: 40s ribosomal protein s5, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7Q_ ribosome Chain: Q: ribosomal protein l15; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7N_ ribosome Chain: N: 60s ribosomal protein l13; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7d_ ribosome Chain: D: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zeyO_ ribosome Chain: O: ribosomal protein s19, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c4iqzD_ unknown function Chain: D: dna-directed rna polymerase subunit beta'; the crystal structure of a large insert in rna polymerase (rpoc)2 subunit from e. coli
c3zf7T_ ribosome Chain: T: 60s ribosomal protein l19, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zeyU_ ribosome Chain: U: 40s ribosomal protein s25, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zf7j_ ribosome Chain: J: ribosomal protein; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c3zeyR_ ribosome Chain: R: 40s ribosomal protein s21, putative; high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
c2m46A_ oxidoreductase Chain: A: arsenate reductase, putative; solution nmr structure of sacol0876 from staphylococcus aureus col,2 nesg target zr353 and csgid target idp00841


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Please cite: The Phyre2 web portal for protein modeling, prediction and analysis
Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]
 
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Lawrence Kelley, Michael Sternberg 
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