|   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | R | P | V | R | L | D | H | T | V | V | R | E | R | L | L | A | K | L | S | G | A | N | . |
. |
. |
. |
. |
N | F | R | L | A | L | I | T | S | P | A | G | Y | G | K | T | T | L | I | S | Q | W | . |
. |
. |
. |
. |
. |
A | A | G | K | N | D | I | G | W | Y | S | L | D | E | G | D | N | Q | Q | E | R | F | A | S |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |
|   |   |   |   | . | . | . | . | . |   |   |   |   |
|   |
|   |
|   |   |
|
|
|
|
|   |
|   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | V | P | Q | R | P | V | V | F | V | T | R | K | K | L | V | N | A | I | Q | Q | K | L | S | K | L | K | G | E | P | G | W | V | T | I | H | G | M | A | G | C | G | K | S | V | L | A | A | E | A | V | R | D | H | S | L | L | E | G | C | F | P | G | G | V | H | W | V | S | V | G | K | Q | D | K | S | G | L | L | M |
Template Known Secondary structure |   |
T |
|
|
|
|
| S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | T | S | T | T | S |
|  |  |  |  |  |  |
|
| T | T | S | S |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
| T | T |
|  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
118 | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . |
  |
  |   |
77 | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | L | I | A | A | V | Q | Q | A | T | N | G | H | C | A | I | C | E | T | M | A | Q | K | R | Q | Y | A | S | L | T | S | L | F | A | Q | L | F | I | E | L | A | E | W | H | S | P | L | Y | L | V | I | D | D | Y | H | L | I | T | N | P | V | I | H | E | S | M | R | F | F | I | R | H | Q | P | E | N | L | T | L | V |
Query Conservation |   |
  |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
K | L | Q | N | L | C | T | R | L | D | . |
. |
. |
. |
. |
. |
Q | D | E | S | F | S | Q | R | L | P | L | N | I | E | E | A | K | D | R | L | R | I | L | M | L | R | K | H | P | R | S | L | L | I | L | D | D | V | W | D | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | V | L | K | A | F | D | S | Q | C | Q | I | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | T | T |
|
| S |
| S | S |
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T |
|  |  |  |  |  |  |  |
|
|  | . | . | . | . | . | . | . | . | . | . |  |  |  |  | T | T |
| S | S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
198 | . | 200 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | 250 | . | . | . | . | . | . | . | . | . | 260 | . |
  |
  |   |
157 | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
|
. | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | S | R | N | L | P | Q | L | G | I | A | N | L | R | V | R | D | Q | L | L | E | I | G | S | Q | Q | L | A | F | T | H | Q | E | A | K | Q | F | F | D | C | R | L | S | S | P | I | E | A | . |
. |
A | E | S | S | R | I | C | D | D | V | S | G | W | A | T | A | L | Q | L | I | A | L | S | A | R | Q | N | T | H |
Query Conservation |   |
  |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |
|   |   |   |   |   | . | . |   |   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |   | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
L | T | T | R | D | K | . |
. |
. |
. |
. |
S | V | T | D | S | V | M | G | P | K | Y | V | V | P | V | E | S | S | L | G | K | E | K | G | L | E | I | L | S | L | F | V | N | M | K | K | A | D | L | P | E | Q | A | H | S | I | I | K | E | C | K | G | S | P | L | V | V | S | L | I | G | A | L | L | R | D | F | P | N |
Template Known Secondary structure |   |
 |  |  | S |
| G | . | . | . | . | . | G | G | G | T | T |
|
| S |
|  |  |  |  |  |
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | S |
| G | G | G | S |
| T |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|  | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
262 | . | . | . | . | . | |
|
|
|
|
. | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . |
  |
  |   |
235 | . | . | . | . | 240 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | A | H | K | S | A | R | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | A | G | I | N | A | S | H | L | S | D | Y | L | V | D | E | V | L | D | N | V | D | L | A | T | R | H | F | L | L | K | S | A | I | L | R | S | . |
. |
. |
. |
. |
M | N | D | A | L | I | T | R | V | T | G | E | E | N | G | Q | M | R | L | E |
Query Conservation |   |
  |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
R | W | E | Y | Y | L | K | Q | L | Q | N | K | Q | F | K | R | I | R | K | S | S | S | Y | D | Y | E | A | L | D | E | A | M | S | I | S | V | E | M | L | R | E | D | I | K | D | Y | Y | T | D | L | S | I | L | Q | K | D | V | K | V | P | T | K | V | L | C | I | L | W | D | M | E | T | E | E | V | E | D | I | L | Q |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  | S |
|
|
|
|
| S | S |
|
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |  |  |  |  | G | G | G |
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
337 | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . |
  |
  |   |
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | I | E | R | Q | G | L | F | L | Q | R | M | D | D | T | G | E | W | F | C | Y | H | P | L | F | G | N | F | L | R | Q | R | C | Q | W |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
E | F | V | N | K | S | L | L | F | C | D | R | N | G | K | S | F | R | Y | Y | L | H | D | L | Q | V | D | F | L | T | E | K | N | C | S |
Template Known Secondary structure |   |
 |  |  |  | T | T | S | S |  |  |  |  |  | T | T |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | T | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
417 | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . |
  |