Job Description P43329 Confidence 100.00% Date Thu Jan 5 12:02:17 GMT 2012 Rank 6 Aligned Residues 366 % Identity 19% Template c2wv9A_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:flavivirin protease ns2b regulatory subunit, flavivirin PDBTitle: crystal structure of the ns3 protease-helicase from murray2 valley encephalitis virus Resolution 2.75 Å

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		88	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	A	I	R	D	H	Q	V	V	I	V	A	G	E	T	G	S	G	K	T	T	Q	L	P	K	I	C	M	E	L	G	R	G	I	K	G	L	I	G	H	T	Q	P	R	R	L	A	A	R	T	V	A	N	R	I	A	E	E	L	K	T	E	P	G	G	C	I	G	Y	K	V	R	F	S	D	H	V	S	D	N
Query Conservation
Alig confidence																																																										.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																										.	.	.	.	.	.	.	.	.	.	.
Template Sequence		E	M	L	K	K	R	Q	L	T	V	L	D	L	H	P	G	A	G	K	T	R	R	I	L	P	Q	I	I	K	D	A	I	Q	K	R	L	R	T	A	V	L	A	P	T	R	V	V	A	A	E	M	A	E	A	L	R	.	.	.	.	.	.	.	.	.	.	.	G	L	P	V	R	Y	L	T	P	R	E	H	S
Template Known Secondary structure		G	G	G	S	T	T									T	T	T	T	T	T	T	T												T	T								S	S											T	T	.	.	.	.	.	.	.	.	.	.	.	T	S
Template Predicted Secondary structure																																																										.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		182	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.												.	.	240	.	.	.	.	.	.	.	.	.	250
		168	.			170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.
Predicted Secondary structure				.	.
Query SS confidence				.	.
Query Sequence		T	M	.	.	V	K	L	M	T	D	G	I	L	L	A	E	I	Q	Q	D	R	L	L	M	Q	Y	D	T	I	I	I	D	E	A	H	E	R	S	L	N	I	D	F	L	L	G	Y	L	K	E	L	L	P	R	R	P	D	L	K	I	I	I	T	S	A	T	I	D	P	E	R	F	S	R	H	F	N	N	A	P
Query Conservation				.	.
Alig confidence				.	.																																																	.
Template Conservation																																																						.
Template Sequence		G	N	E	I	V	D	V	M	C	H	A	T	L	T	H	R	L	M	S	P	L	R	V	P	N	Y	N	L	F	V	M	D	E	A	H	F	T	D	P	A	S	I	A	A	R	G	Y	I	A	T	R	V	.	E	A	G	E	A	A	A	I	F	M	T	A	T	P	P	G	T	S	D	P	F	P	D	T	N	S	P
Template Known Secondary structure		S																		S	S	S						S						S	T	T																		.		T	T	S								S	S		T	T				S	S				S	S
Template Predicted Secondary structure																																																						.
Template SS confidence
		254	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.		.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.
		246	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	I	E	V	S	G	R	T	Y	P	V	E	V	R	Y	R	P	I	V	E	E	A	D	D	T	E	R	D	Q	L	Q	A	I	F	D	A	V	D	E	L	S	Q	E	S	H	G	D	I	L	I	F	M	S	G	E	R	E	I	R	D	T	A	D	A	L	N	K	L	N	L	R	H	T	E	I	L	P	L	Y	A
Query Conservation
Alig confidence		.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																															.	.	.
Template Conservation		.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																															.	.	.
Template Sequence		.	V	H	D	V	S	S	E	I	P	D	R	A	W	S	S	G	F	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	W	I	T	D	Y	A	G	K	T	V	W	F	V	A	S	V	K	M	S	N	E	I	A	Q	C	L	Q	R	A	.	.	.	G	K	R	V	I	Q	L	N	R
Template Known Secondary structure		.										S	S			S	S			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.					S			S							S	S													T	T	.	.	.	T								S
Template Predicted Secondary structure		.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																															.	.	.
Template SS confidence
			333	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.																					350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.				380	.	.	.	.	.	.	.	.
		326	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.			.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.
Predicted Secondary structure																																																	.	.
Query SS confidence																																																	.	.
Query Sequence		R	L	S	N	S	E	Q	N	R	V	F	Q	S	H	S	G	R	R	I	V	L	A	T	N	V	A	E	T	S	L	T	V	P	G	I	K	Y	V	I	D	P	G	T	A	R	I	S	.	.	R	Y	S	Y	R	T	K	V	Q	R	L	P	I	E	P	I	S	Q	A	S	A	N	Q	R	K	G	R	C	G	R	V
Query Conservation																																																	.	.
Alig confidence												.	.																						.														.	.
Template Conservation												.	.																						.
Template Sequence		K	S	Y	D	T	E	Y	P	K	C	.	.	K	N	G	D	W	D	F	V	I	T	T	D	I	S	E	M	G	A	N	F	G	.	A	S	R	V	I	D	C	R	K	S	V	K	P	T	I	L	D	E	G	E	G	R	V	I	L	S	V	P	S	A	I	T	S	A	S	A	A	Q	R	R	G	R	V	G	R	N
Template Known Secondary structure		S	S					G	G	G	G	.	.	G	T				S						G	G	G	G	T	T					.		S																S	T	T								S													T	T	S	S
Template Predicted Secondary structure												.	.																						.
Template SS confidence
		389	390	.	.	.	.	.	.	.	.			.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.		420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.
		404	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	E	G	I	C	I	R	L	Y	S	E	D	D	F	L	S	R	P	E	F	T	D	P	E	I	L	R	T	N	L	A	S	V	I	L	Q	M	T	A	L	G	L	G	D	I	A	A	F	P	F	V	E	A	P	D	K	R	N	I	Q	D	G	V	R	L	L	E	E	L	G	A	I	T	T	D	E	Q	A	S	A
Query Conservation
Alig confidence											.	.	.	.																																																									.	.	.	.	.	.	.	.	.	.	.
Template Conservation											.	.	.	.																																																									.	.	.	.	.	.	.	.	.	.	.
Template Sequence		P	S	Q	I	G	D	E	Y	H	.	.	.	.	Y	G	G	G	T	S	E	D	D	T	M	L	A	H	W	T	E	A	K	I	L	L	D	N	I	H	L	P	N	G	L	V	A	Q	L	Y	G	P	E	R	D	K	T	Y	T	M	D	G	E	Y	R	L	R	G	E	E	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		S	S								.	.	.	.			S							T	T	B												T	S		B	T	T	T	B						G	G	G	G	G	G					T	T	T	T							.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure											.	.	.	.																																																									.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		466	.	.	.	470	.	.	.	.					.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530
		484	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	K	L	T	P	L	G	R	Q	L	S	Q	L	P	V	D	P	R	L	A	R	M	V	L	E	A
Query Conservation
Alig confidence		.	.
Template Conservation		.	.
Template Sequence		.	.	R	K	T	F	L	E	L	I	K	T	A	D	L	P	V	W	L	A	Y	K	V	A	S	N
Template Known Secondary structure		.	.										T	S
Template Predicted Secondary structure		.	.
Template SS confidence
				531	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.