Job Description P43329 Confidence 100.00% Date Thu Jan 5 12:02:17 GMT 2012 Rank 5 Aligned Residues 419 % Identity 20% Template c2vbcA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:dengue 4 ns3 full-length protein; PDBTitle: crystal structure of the ns3 protease-helicase from dengue2 virus Resolution 3.15 Å

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		90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.		160	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																								.
Query SS confidence																																																																								.
Query Sequence		I	R	D	H	Q	V	V	I	V	A	G	E	T	G	S	G	K	T	T	Q	L	P	K	I	C	M	E	L	G	R	G	I	K	G	L	I	G	H	T	Q	P	R	R	L	A	A	R	T	V	A	N	R	I	A	E	E	L	K	T	E	P	G	G	C	I	G	Y	K	V	R	.	F	S	D	H	V	S	D	N	T
Query Conservation																																																																								.
Alig confidence																																																								.	.	.	.	.	.	.										.
Template Conservation																																																								.	.	.	.	.	.	.
Template Sequence		F	R	K	K	R	L	T	I	M	D	L	H	P	G	A	G	K	T	K	R	I	L	P	S	I	V	R	E	A	L	K	R	R	L	R	T	L	I	L	A	P	T	R	V	V	A	A	E	M	E	E	A	L	R	.	.	.	.	.	.	.	G	L	P	I	R	Y	Q	T	P	A	V	K	S	D	H	T	G	R	E
Template Known Secondary structure			S	T	T									T	T	T			T	T	T												T	T								S	S											T	T	.	.	.	.	.	.	.	T	S							T	T		S						S	S
Template Predicted Secondary structure																																																								.	.	.	.	.	.	.
Template SS confidence
		183	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.								.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.
		169	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	V	K	L	M	T	D	G	I	L	L	A	E	I	Q	Q	D	R	L	L	M	Q	Y	D	T	I	I	I	D	E	A	H	E	R	S	L	N	I	D	F	L	L	G	Y	L	K	E	L	L	P	R	R	P	D	L	K	I	I	I	T	S	A	T	I	D	P	E	R	F	S	R	H	F	N	N	A	P	I	I	E
Query Conservation
Alig confidence																																																				.														.	.	.	.	.	.	.	.	.	.
Template Conservation																																																				.														.	.	.	.	.	.	.	.	.	.
Template Sequence		I	V	D	L	M	C	H	A	T	F	T	T	R	L	L	S	S	T	R	V	P	N	Y	N	L	I	V	M	D	E	A	H	F	T	D	P	C	S	V	A	A	R	G	Y	I	S	T	R	V	E	.	M	G	E	A	A	A	I	F	M	T	A	T	P	.	.	.	.	.	.	.	.	.	.	P	G	S	T	D	P
Template Known Secondary structure																			S						S						S	T	T			S																.		T	S								S	S		.	.	.	.	.	.	.	.	.	.	T	T				S
Template Predicted Secondary structure																																																				.														.	.	.	.	.	.	.	.	.	.
Template SS confidence
		256	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.		.	.	.	.	310	.	.	.	.	.	.	.	.											.	320	.	.	.	.
		249	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	S	G	R	T	Y	P	V	E	V	R	Y	R	P	I	V	E	E	A	D	D	T	E	R	D	Q	L	Q	A	I	F	D	A	V	D	E	L	S	Q	E	S	H	G	D	I	L	I	F	M	S	G	E	R	E	I	R	D	T	A	D	A	L	N	K	L	N	L	R	H	T	E	I	L	P	L	Y	A	R	L	S
Query Conservation
Alig confidence																															.	.	.	.	.	.	.	.	.	.	.																										.	.	.
Template Conservation																															.	.	.	.	.	.	.	.	.	.	.																										.	.	.
Template Sequence		F	P	Q	S	N	S	P	I	E	D	I	E	R	E	I	P	E	R	S	W	N	T	G	F	D	W	I	T	D	.	.	.	.	.	.	.	.	.	.	.	Y	Q	G	K	T	V	W	F	V	P	S	I	K	A	G	N	D	I	A	N	C	L	R	K	S	.	.	.	G	K	R	V	I	Q	L	S	R	K	T	F
Template Known Secondary structure		S				S	S											S	S				S	S							.	.	.	.	.	.	.	.	.	.	.			S							S	S													T	T	.	.	.	T								T	T	T
Template Predicted Secondary structure																															.	.	.	.	.	.	.	.	.	.	.																										.	.	.
Template SS confidence
		325	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.												.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.				.	380	.	.	.	.	.	.	.	.	.	390
		329	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.			.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.
Predicted Secondary structure																																									.	.
Query SS confidence																																									.	.
Query Sequence		N	S	E	Q	N	R	V	F	Q	S	H	S	G	R	R	I	V	L	A	T	N	V	A	E	T	S	L	T	V	P	G	I	K	Y	V	I	D	P	G	.	.	T	A	R	I	S	R	Y	S	Y	R	T	K	V	Q	R	L	P	I	E	P	I	S	Q	A	S	A	N	Q	R	K	G	R	C	G	R	V	S	E	G
Query Conservation																																									.	.
Alig confidence									.	.																						.									.	.																																							.
Template Conservation									.	.																						.																																																	.
Template Sequence		D	T	E	Y	P	K	T	.	.	K	L	T	D	W	D	F	V	V	T	T	D	I	S	E	M	G	A	N	F	R	.	A	G	R	V	I	D	P	R	R	C	L	K	P	V	I	L	T	D	G	P	E	R	V	I	L	A	G	P	I	P	V	T	P	A	S	A	A	Q	R	R	G	R	I	G	R	N	P	A	.
Template Known Secondary structure					T				.	.			S			S						G	G	G	G	T	T					.		S																S	S	S																						T	S	S		S			.
Template Predicted Secondary structure									.	.																						.																																																	.
Template SS confidence
		391	.	.	.	.	.	.			.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.		.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.
		407	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.						.	.	.	.	.	.	.	.	480	.
Predicted Secondary structure																																																																			.	.	.	.	.
Query SS confidence																																																																			.	.	.	.	.
Query Sequence		I	C	I	R	L	Y	S	E	D	D	F	L	S	R	P	E	F	T	D	P	E	I	L	R	T	N	L	A	S	V	I	L	Q	M	T	A	L	G	L	G	D	I	A	A	F	P	F	V	E	A	P	D	K	R	N	I	Q	D	G	V	R	L	L	E	E	.	.	.	.	.	L	G	A	I	T	T	D	E	Q	A
Query Conservation																																																																			.	.	.	.	.
Alig confidence		.	.	.																																																															.	.	.	.	.										.
Template Conservation		.	.	.																																																																													.
Template Sequence		.	.	.	Q	E	D	D	Q	Y	V	F	S	G	D	P	L	K	N	D	E	D	H	A	H	W	T	E	A	K	M	L	L	D	N	I	Y	T	P	E	G	I	I	P	T	L	F	G	P	E	R	E	K	T	Q	A	I	D	G	E	F	R	L	R	G	E	Q	R	K	T	F	V	E	L	M	R	R	G	D	L	.
Template Known Secondary structure		.	.	.	S	S								S							T	T	B											T	T	S			T	T								G	G	G	G	G	G			S		T	T	T	T				T	T											T	S			.
Template Predicted Secondary structure		.	.	.																																																																													.
Template SS confidence
					467	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.
		482	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.					.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.					.	.	550	.	.
Predicted Secondary structure																																				.	.	.	.																																	.	.	.	.
Query SS confidence																																				.	.	.	.																																	.	.	.	.
Query Sequence		S	A	Y	K	L	T	P	L	G	R	Q	L	S	Q	L	P	V	D	P	R	L	A	R	M	V	L	E	A	Q	K	H	G	C	V	.	.	.	.	R	E	A	M	I	I	T	S	A	L	S	I	Q	D	P	R	E	R	P	M	D	K	Q	Q	A	S	D	E	K	H	R	R	.	.	.	.	F	H	D	K	E
Query Conservation																																				.	.	.	.																																	.	.	.	.
Alig confidence		.	.	.	.																															.	.	.	.																																	.	.	.	.
Template Conservation		.	.	.	.
Template Sequence		.	.	.	.	P	V	W	L	S	Y	K	V	A	S	A	G	I	S	Y	K	D	R	E	W	C	F	T	G	E	R	N	N	Q	I	L	E	E	N	M	E	V	E	I	W	T	R	E	G	E	K	K	K	L	R	P	K	W	L	D	A	R	V	Y	A	D	P	M	A	L	K	D	F	K	E	F	A	S	G	R
Template Known Secondary structure		.	.	.	.										T	T	T			S	S			T	T	T	T				G	G	G					T	T								S	S									S	S		B	G	G	G	T	S	S													T
Template Predicted Secondary structure		.	.	.	.
Template SS confidence
						543	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.