Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	I	F	V	Y	G	S	L	R	H	K	Q	G	N	S	H	W	M	T	N	A	Q	L	L	G	D	F	S	I	D	N	Y	Q	L	Y	S	L	G	H	Y	P	G	A	V	P	G	N	G	T	V	H	G	E	V	Y	R	I	D	N
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.
Sequence		A	T	L	A	E	L	D	A	L	R	T	R	G	G	E	Y	A	R	Q	L	I	Q	T	P	Y	G	S	A	W	M	Y	V	Y	Q	R	P	V	D	G	L	K	L	I	E	S	G	D	W	L	D	R	D	K
Secondary structure
SS confidence
Disorder																																																?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1xhs chain A Region: 1 - 113 Aligned: 113 Modelled: 113 Confidence: 100.0% Identity: 100% Fold: Gamma-glutamyl cyclotransferase-like Superfamily: Gamma-glutamyl cyclotransferase-like Family: Gamma-glutamyl cyclotransferase-like Phyre2 PDB 1v30 chain A Region: 1 - 111 Aligned: 108 Modelled: 111 Confidence: 100.0% Identity: 32% Fold: Gamma-glutamyl cyclotransferase-like Superfamily: Gamma-glutamyl cyclotransferase-like Family: Gamma-glutamyl cyclotransferase-like Phyre2 PDB 2qik chain A Region: 3 - 109 Aligned: 99 Modelled: 103 Confidence: 100.0% Identity: 29% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0131 protein ykqa; PDBTitle: crystal structure of ykqa from bacillus subtilis. northeast2 structural genomics target sr631 Phyre2 PDB 1vkb chain A Region: 2 - 108 Aligned: 107 Modelled: 107 Confidence: 99.9% Identity: 31% Fold: Gamma-glutamyl cyclotransferase-like Superfamily: Gamma-glutamyl cyclotransferase-like Family: Gamma-glutamyl cyclotransferase-like Phyre2 PDB 3jub chain A Region: 1 - 104 Aligned: 104 Modelled: 104 Confidence: 99.9% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:aig2-like domain-containing protein 1; PDBTitle: human gamma-glutamylamine cyclotransferase Phyre2 PDB 2jqv chain A Region: 2 - 108 Aligned: 102 Modelled: 107 Confidence: 99.9% Identity: 25% PDB header:structural genomics Chain: A: PDB Molecule:aig2 protein-like; PDBTitle: solution structure at3g28950.1 from arabidopsis thaliana Phyre2 PDB 2g0q chain A Region: 2 - 108 Aligned: 102 Modelled: 107 Confidence: 99.9% Identity: 26% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:at5g39720.1 protein; PDBTitle: solution structure of at5g39720.1 from arabidopsis thaliana Phyre2 PDB 2rbh chain A Region: 1 - 101 Aligned: 101 Modelled: 101 Confidence: 99.8% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:gamma-glutamyl cyclotransferase; PDBTitle: gamma-glutamyl cyclotransferase Phyre2 PDB 2o8r chain A domain 4 Region: 90 - 112 Aligned: 23 Modelled: 19 Confidence: 49.4% Identity: 22% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Polyphosphate kinase C-terminal domain Phyre2 PDB 1xdp chain A domain 4 Region: 90 - 112 Aligned: 23 Modelled: 23 Confidence: 45.9% Identity: 26% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Polyphosphate kinase C-terminal domain Phyre2 PDB 2o8r chain A Region: 90 - 112 Aligned: 23 Modelled: 19 Confidence: 25.8% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of polyphosphate kinase from2 porphyromonas gingivalis Phyre2 PDB 3eoi chain B Region: 2 - 52 Aligned: 51 Modelled: 51 Confidence: 11.8% Identity: 14% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:pilm; PDBTitle: crystal structure of putative protein pilm from escherichia coli b7a Phyre2 PDB 1hf2 chain A domain 1 Region: 2 - 10 Aligned: 9 Modelled: 9 Confidence: 8.2% Identity: 22% Fold: Single-stranded right-handed beta-helix Superfamily: Cell-division inhibitor MinC, C-terminal domain Family: Cell-division inhibitor MinC, C-terminal domain Phyre2 PDB 1ynh chain A domain 1 Region: 1 - 7 Aligned: 7 Modelled: 7 Confidence: 7.9% Identity: 71% Fold: Pentein, beta/alpha-propeller Superfamily: Pentein Family: Succinylarginine dihydrolase-like Phyre2 PDB 1xdo chain B Region: 71 - 112 Aligned: 42 Modelled: 42 Confidence: 6.7% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of escherichia coli polyphosphate kinase Phyre2 PDB 1hf2 chain A Region: 2 - 10 Aligned: 9 Modelled: 9 Confidence: 5.4% Identity: 22% PDB header:cell division protein Chain: A: PDB Molecule:septum site-determining protein minc; PDBTitle: crystal structure of the bacterial cell-division inhibitor2 minc from t. maritima Phyre2 1 d1xhsa_ 2 d1v30a_ 3 c2qikA_ 4 d1vkba_ 5 c3jubA_ 6 c2jqvA_ 7 c2g0qA_ 8 c2rbhA_ 9 d2o8ra4 10 d1xdpa4 11 c2o8rA_ 12 c3eoiB_ 13 d1hf2a1 14 d1ynha1 15 c1xdoB_ 16 c1hf2A_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1xhsa_ 100.0 100 Fold:Gamma-glutamyl cyclotransferase-like Superfamily:Gamma-glutamyl cyclotransferase-like Family:Gamma-glutamyl cyclotransferase-like 2 d1v30a_ 100.0 32 Fold:Gamma-glutamyl cyclotransferase-like Superfamily:Gamma-glutamyl cyclotransferase-like Family:Gamma-glutamyl cyclotransferase-like 3 c2qikA_ 100.0 29 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0131 protein ykqa; PDBTitle: crystal structure of ykqa from bacillus subtilis. northeast2 structural genomics target sr631 4 d1vkba_ 99.9 31 Fold:Gamma-glutamyl cyclotransferase-like Superfamily:Gamma-glutamyl cyclotransferase-like Family:Gamma-glutamyl cyclotransferase-like 5 c3jubA_ 99.9 27 PDB header:transferase Chain: A: PDB Molecule:aig2-like domain-containing protein 1; PDBTitle: human gamma-glutamylamine cyclotransferase 6 c2jqvA_ 99.9 25 PDB header:structural genomics Chain: A: PDB Molecule:aig2 protein-like; PDBTitle: solution structure at3g28950.1 from arabidopsis thaliana 7 c2g0qA_ 99.9 26 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:at5g39720.1 protein; PDBTitle: solution structure of at5g39720.1 from arabidopsis thaliana 8 c2rbhA_ 99.8 20 PDB header:transferase Chain: A: PDB Molecule:gamma-glutamyl cyclotransferase; PDBTitle: gamma-glutamyl cyclotransferase 9 d2o8ra4 49.4 22 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 10 d1xdpa4 45.9 26 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 11 c2o8rA_ 25.8 22 PDB header:transferase Chain: A: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of polyphosphate kinase from2 porphyromonas gingivalis 12 c3eoiB_ 11.8 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:pilm; PDBTitle: crystal structure of putative protein pilm from escherichia coli b7a 13 d1hf2a1 8.2 22 Fold:Single-stranded right-handed beta-helix Superfamily:Cell-division inhibitor MinC, C-terminal domain Family:Cell-division inhibitor MinC, C-terminal domain 14 d1ynha1 7.9 71 Fold:Pentein, beta/alpha-propeller Superfamily:Pentein Family:Succinylarginine dihydrolase-like 15 c1xdoB_ 6.7 17 PDB header:transferase Chain: B: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of escherichia coli polyphosphate kinase 16 c1hf2A_ 5.4 22 PDB header:cell division protein Chain: A: PDB Molecule:septum site-determining protein minc; PDBTitle: crystal structure of the bacterial cell-division inhibitor2 minc from t. maritima

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0