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Job DescriptionP27240
Confidence99.66%DateThu Jan 5 11:43:19 GMT 2012
Rank202Aligned Residues177
% Identity18%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   28.30.........40.........50.........60.........70.........80.........90.........100.......
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Query Sequence  FLSYNINIIKVFRSIDDTKVMLIDTDYGKLILKVFSPKVKRNERFFKSLLKGDYYERLFEQTQKVRNEGLNTLNDFYLLA
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Template Sequence  TVARDITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWF. . . . . . . . . . . . . . . . . . RETELYNTVMLRHENILG
Template Known Secondary structure 
TTTTTTTT
GGG..................S



TTB

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   203......210.........220.........230.........240...... ...250.........260....
 
   108.110. ........120.........130... ......140.........150...... ...160........
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Query Sequence  ERKT. . . . LRFVHTYIMIIEYIDGIELCDM. . . . . . . PDIDDALKNKIQQSINALHQHGM. . . . . . . . VSGDPHRGNFII
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Template Sequence  FIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILV
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TT
B

B
S
B
STT
B

S

SGGG
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   265....270.........280.........290.........300.........310.........320.........330.........340....
 
   169 170.........180.........190........ .200.........210.........220..
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Query Sequence  K. NGEVRIIDLSGKRASAQRKAKDRIDLERH. . . . . . . . . . . . . . . . . . . . . . YGIKNEIRDLGYYLLVYRKKMRNF
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Template Sequence  KKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSN
Template Known Secondary structure 
TTS



TT
TTTT








GGG

TT


TT
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BT
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   345....350.........360.........370.........380.........390.........400.........410.........420.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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