Job Description P27240 Confidence 99.80% Date Thu Jan 5 11:43:19 GMT 2012 Rank 143 Aligned Residues 181 % Identity 12% Template c3lxnA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.50 Å

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		28	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.					.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.
Predicted Secondary structure																													.	.	.	.
Query SS confidence																													.	.	.	.
Query Sequence		F	L	S	Y	N	I	N	I	I	K	V	F	R	S	I	D	D	T	K	V	M	L	I	D	T	D	Y	.	.	.	.	G	K	L	I	L	K	V	F	S	P	K	V	K	R	N	E	R	F	F	K	S	L	L	K	G	D	Y	Y	E	R	L	F	E	Q	T	Q	K	V	R	N	E	G	L	N	T	L	N	D	F
Query Conservation																													.	.	.	.
Alig confidence																													.	.	.	.																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		F	H	K	R	Y	L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	A	D	A	G	P	Q	H	R	S	G	W	K	Q	E	I	D	I	L	R	T	L	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	H	E
Template Known Secondary structure				G	G	G											S	S										T	T	S	S	S												S	S																					.	.	.	.	.	.	.	.	.	.	.	.	.	.		T
Template Predicted Secondary structure																																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		892	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.															.	.
		104	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.										.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.		170	.	.	.
Predicted Secondary structure																																.	.	.	.	.	.	.	.	.																																					.
Query SS confidence																																.	.	.	.	.	.	.	.	.																																					.
Query Sequence		Y	L	L	A	E	R	K	T	L	R	F	V	H	T	Y	I	M	I	I	E	Y	I	D	G	I	E	L	C	D	M	.	.	.	.	.	.	.	.	.	P	D	I	D	D	A	L	K	N	K	I	Q	Q	S	I	N	A	L	H	Q	H	G	M	V	S	G	D	P	H	R	G	N	F	I	I	K	.	N	G	E	V
Query Conservation																																.	.	.	.	.	.	.	.	.																																					.
Alig confidence																																.	.	.	.	.	.	.	.	.																																					.
Template Conservation
Template Sequence		H	I	I	K	Y	K	G	C	C	E	D	A	G	A	A	S	L	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	P	R	H	S	I	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G	M	A	Y	L	H	A	Q	H	Y	I	H	R	D	L	A	A	R	N	V	L	L	D	N	D	R	L	V
Template Known Secondary structure		T	B										T	T	T	T										T	T		B					G	G	G	S																								T	T				S			S	G	G	G						T	T
Template Predicted Secondary structure
Template SS confidence
		958	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.
		174	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.												.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.
Predicted Secondary structure																											.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																											.	.	.	.	.	.	.	.	.	.	.
Query Sequence		R	I	I	D	L	S	G	K	R	A	S	A	Q	R	K	A	K	D	R	I	D	L	E	R	H	.	.	.	.	.	.	.	.	.	.	.	Y	G	I	K	N	E	I	R	D	L	G	Y	Y	L	L	V	Y	R	K	K	M	R	N	F
Query Conservation																											.	.	.	.	.	.	.	.	.	.	.
Alig confidence																											.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		K	I	G	D	F	G	L	A	K	A	V	P	E	G	H	E	Y	R	V	G	D	S	P	V	F	W	Y	A	P	E	C	L	K	E	Y	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	H	C	D	S	S
Template Known Secondary structure							T	T						T	T				B						G	G	G								S		B																			T	T	T		G	G
Template Predicted Secondary structure
Template SS confidence
		1038	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions